Abstract: The present disclosure provides use of doxepin hydrochloride in preparation of an antiviral drug and relates to the technical field of medicine. Studies show that the doxepin hydrochloride exhibits strong antiviral activity against Coxsackievirus B type 1, type 2 and type 3 and has a 50% minimal inhibitory concentration (IC50) value of 10.12±0.85 ?M. In addition, it is also found that the doxepin hydrochloride inhibits virus replication at an early stage of an infection cycle, rather than affecting an entry or assembly process. Meanwhile, some host genes associated with a mechanism are found through target prediction and gene association network analysis. The above findings provide a foundation and a basis for use of the doxepin hydrochloride in treatment of Coxsackievirus B infection.

Abstract: Systems and methods for reconstructing images for computed tomography are provided. Image reconstruction can be based on a realistic polychromatic physical model, and can include use of both an analytical algorithm and a single-variable optimization method. The optimization method can be used to solve the non-linear polychromatic X-ray integral model in the projection domain, resulting in an accurate decomposition for sinograms of two physical basis components.

Abstract: The present disclosure provides an array substrate, a liquid crystal display panel and a liquid crystal display device, including: a base substrate; gate lines each extending in a first direction on the base substrate; data lines each extending in a second direction intersecting the first direction; pixel units located in regions defined by the gate lines and the data lines; each pixel unit has a first side and a second side each extending in the second direction and opposite to each other in the first direction; each pixel unit includes a first electrode including a plurality of strip-shaped electrodes, at least part of the strip-shaped electrodes each have a first part and a second part extending in different directions, first parts are connected at the first side, second parts are disconnected at the second side, and lengths of the first part and the second part are different.

Abstract: Disclosed are a metal aluminum nano-adjuvant, a vaccine composition and a preparation method therefor and a use thereof. The vaccine adjuvant comprises metal aluminum nanoparticles, and can be used as a candidate adjuvant for preventive vaccines and therapeutic vaccines for various diseases such as infections, autoimmune diseases and tumors. The combined use of the vaccine adjuvant provided by the present disclosure and antigen can effectively enhance the humoral immune response and the cellular immune response of the vaccine, and the enhancement effect is significantly better than that of the commercially available aluminum hydroxide adjuvant.

Abstract: An electronic device may include a display system configured to produce light and a lens assembly that receives the light from the display panel. The lens assembly may include one or more lens elements, one or more cholesteric liquid crystal layers, one or more quarter wave plates, one or more linear polarizers, one or more reflective polarizers, and/or a partially reflective layer. The display system may include a display panel, a linear polarizer, one or more quarter wave plates, and/or a geometric phase lens.

Abstract: Disclosed are apparatus, electronic device, and method for stitching dual-camera images. The method includes collecting two images having overlapping photographic content. The method includes extracting and matching feature points of the two images. The method includes roughly aligning the two images by using a homography matrix. The method includes accurately aligning the two images by using a least squares method to complete stitching the two images.

Abstract: A color filter substrate, a display panel and a display device are provided. The color filter substrate includes: a base substrate; a color conversion layer on the base substrate; a covering layer on a side of the color conversion layer away from the base substrate; and a polarizing layer on a side of the covering layer away from the base substrate. The polarizing layer includes a wire grid polarizer. The covering layer includes a first covering sub-layer and a second covering sub-layer, the first covering sub-layer is located on the side of the color conversion layer away from the base substrate, the second covering sub-layer is located on a side of the first covering sub-layer away from the base substrate, and a material of the first covering sub-layer is different from a material of the second covering sub-layer.

Abstract: Disclosed is a chip-level disc-type acousto-optic standing wave gyroscope including a substrate and a gyroscope structure placed on an upper surface of the substrate; the substrate is in a shape of a circular disc; the gyroscope structure includes an acoustic wave drive module and an optical detection module, the acoustic wave drive module is arranged in a circular shape taking the center of the circular disc as an origin and extending outward radially, and the optical detection module is arranged in the middle of the acoustic wave drive module and is annular; the acoustic wave drive module includes an annular interdigitated transducer, a metal electrode layer group uniformly sputtered on the annular interdigitated transducer, annularly arranged metallic pillars and an annular reflection grating, respectively placed in sequence from center of the disk radially to periphery of the disk; the optical detection module includes a first grating coupler, an optical waveguide at a light source input end, a first coup

Abstract: A light-emitting substrate includes a pixel layer including a plurality of sub-pixels. Each sub-pixel includes a light-emitting element, a first light extraction layer, a first material layer, and a second material layer. The light-emitting element is configured to emit light of a first color. The first light extraction layer is configured to deflect the light emitted from the light-emitting element into the first material layer at a preset angle. The first material layer and the second material layer are configured to enable the light deflected at the preset angle to propagate in the first material layer and the second material layer. The plurality of sub-pixels include at least one first sub-pixel. Of a first material layer and a second material layer included in the at least one first sub-pixel, at least the second material layer includes a first light conversion material.

Abstract: The present invention provides a built-in ripple injection circuit and a control chip, in which a divided feedback voltage is obtained by division of an output voltage by a feedback circuit, and high-frequency ripple in the output voltage is obtained by an operational amplifier and a first capacitor. Moreover, the high-frequency ripple is injected at a third terminal of a source follower. As a result, the feedback voltage is a superimposition of the divided feedback voltage with the high-frequency ripple. This can enhance stability and interference resilience of a power supply system operating in a ripple-based COT control mode. Further, the built-in ripple circuit can be integrated in the control chip. This dispenses with the use of a large capacitor and satisfactorily addresses applications requiring on-chip integration of the feedback circuit, reducing the cost of the power supply system.

Abstract: Methods, systems, and computer-readable storage media for receiving a workload period, during which a workload is applied to a database system, providing a set of ML models based on historical data representative of historical executions of the workload over the workload period, each ML model configured to predict a cluster arrival rate curve (cARC), and during execution of the workload period and, for each timeslice of a plurality of timeslice of the workload period: providing a predicted cARC from each ML model, the predicted cARC representative of a predicted workload, determining column visiting times for each of a plurality of columns of each of a plurality of tables stored in the database system, generating a column list based on the column visiting times, and loading column data representative of columns included in the column list into low-latency memory prior to execution of a workload during the respective timeslice.

Abstract: Qubit devices require fast operation, long coherence, and large scalability to be viable for implementation in quantum computing systems. A qubit platform device having long coherence, scalability, and fast operation includes a substrate, or trap region, configured to structurally support solid neon thereon. A trap electrode is configured to provide a trap voltage to the trap region and which creates a confining electrical field to a confining region adjacent to the trap region. The confining region being a region of space to confine an electron therein, confining the electron against the solid neon. First and second sets of guard electrodes are configured to provide variable electric potentials to first and second guard regions to allow for trapping and manipulation of a single electron in the confining region.

Abstract: Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.

Abstract: Systems and methods, for selecting a neural network for a machine learning (ML) problem, are disclosed. A method includes accessing an input matrix, and accessing an ML problem space associated with an ML problem and multiple untrained candidate neural networks for solving the ML problem. The method includes computing, for each untrained candidate neural network, at least one expressivity measure capturing an expressivity of the candidate neural network with respect to the ML problem. The method includes computing, for each untrained candidate neural network, at least one trainability measure capturing a trainability of the candidate neural network with respect to the ML problem. The method includes selecting, based on the at least one expressivity measure and the at least one trainability measure, at least one candidate neural network for solving the ML problem. The method includes providing an output representing the selected at least one candidate neural network.

Abstract: Provided herein are methods and systems for reducing roughness of an EUV resist and improving etched features. The methods involve descumming an EUV resist, filling divots of the EUV resist, and protecting EUV resists with a cap. The resulting EUV resist has smoother features and increased selectivity to an underlying layer, which improves the quality of etched features. Following etching of the underlying layer, the cap may be removed.

Abstract: The present invention provides a marker set for evaluating the development of an infant's communication ability. The marker set is composed of the following fatty acids: C18:3n6, C18:2n6t, C20:3n3, C18:3n3, C18:2n6c, C20:4n6, C20:3n6, C22:6n3, and C20:5n3. The present invention further provides a method for evaluating the development of an infant's communication ability using the marker set. The present invention achieves the evaluation on the development of an infant's communication ability by extracting and detecting the contents of particular fatty acids in a breast milk or dairy product sample fed to an infant, and the development level of the infant among the peers can be inferred based on the evaluation result, so as to give suggestions relevant to diet and nutrition for the mother timely. The method is low in cost, simple and effective, and suitable for large-scale evaluation.

Abstract: Systems and methods for selecting a neural network for a machine learning problem are disclosed. A method includes accessing an input matrix. The method includes accessing a machine learning problem space associated with a machine learning problem and multiple untrained candidate neural networks for solving the machine learning problem. The method includes computing, for each untrained candidate neural network, at least one expressivity measure capturing an expressivity of the candidate neural network with respect to the machine learning problem. The method includes computing, for each untrained candidate neural network, at least one trainability measure capturing a trainability of the candidate neural network with respect to the machine learning problem. The method includes selecting, based on the at least one expressivity measure and the at least one trainability measure, at least one candidate neural network for solving the machine learning problem.

Abstract: A deep neural network-based method for detecting living cell morphology may include identifying and locating one or more living cells within an acquired image to be detected by using a deep neural network-based target detection model, so as to extract one or more living single cell images. segmenting the image of the one or more living single cells by using a deep neural network-based cell segmentation model, so as to obtain one or more feature part of the one or more living single cells. and analyzing and determining a morphological parameter of the one or more living single cells based on the one or more feature parts. Thus, the activity of the detected cells can be ensured, and a non-destructive, accurate, and rapid detection of living cell morphology can be achieved.

Abstract: The present disclosure provides a preparation method for hydrothermal synthesis of fly ash silicate aggregate including: mixing sodium metasilicate, potassium hydroxide, and inorganic-organic hybrid excitation monomer as raw materials to obtain an inorganic-organic composite activator; preparing a silicate aggregate raw material, mixing measured fly ash, carbide slag, quicklime, and vitrified micro bubble by mass, adding the inorganic-organic composite activator and continue stirring to produce a mixture; forming a ball disc, wetting an expanded perlite that forms a core of the ball by spraying water, adding a prepared mixture, spraying water while adding, standing and curing, performing a maturation and activation treatment in an autoclave, undergoing a silicon calcium reaction for a hydrothermal synthesis to obtain the silicate aggregates.

Abstract: The present invention belongs to the technical field of biomedicine, and mainly relates to a miR-7-5p mimic for inhibiting migration and invasion of breast cancer, a screening method and an application thereof. The sequence of the miR-7-5p is shown in SEQ ID NO.1. The present invention has found that the miR-7-5p mimic generates a significant inhibitory effect on breast cancer through targeted inhibition of the molecular mechanism of RYK. In vitro culture system, the miR-7-5p mimic can function to inhibit migration and invasion capabilities of breast cancer. The miR-7-5p mimic can inhibit RYK protein and mRNA levels in breast cancer. In nude mice, the miR-7-5p mimic can also significantly inhibit migration and invasion capabilities of breast cancer. Therefore, the present invention demonstrates that the miR-7-5p mimic can be a small-nucleic-acid drug to significantly inhibit breast cancer metastasis.