Abstract: The present invention reveals a comprehensive health evaluation method and system for the top cover drainage system of a hydroelectric generating set. It analyzes health evaluation factors at multiple levels, processing the drainage system into a component evaluation set and a state variable evaluation set. A combined weighting method, incorporating both initial weight and objective weighting methods, is used for comprehensive weighting across the levels. Standard requirements and scoring criteria are established, enabling sequential calculation of scores from state variables to components, then to the top cover drainage system, progressing from low to high levels. This process evaluates the health degrees at each level, resulting in a comprehensive and reliable health evaluation outcome. Consequently, it effectively addresses technical issues in prior art, such as limitations in health evaluation methods and the low reliability and universality of evaluation results.

Abstract: The present disclosure provides a triggering method of an intervention prompt on the basis of user smoking behavior records, comprising: receiving smoking behavior record data associated with a user, wherein the smoking behavior record data includes a plurality of smoking behavior records; analyzing the smoking behavior record data to determine smoking behavior location data associated with each of the plurality of smoking behavior records; calculating a distance between locations indicated by every two smoking behavior location data; recording a first number of smoking behavior records in which the distance is less than a first distance as a set of smoking behavior record data; in a case where the first number is greater than a first threshold, determining a prompt range on the basis of the smoking behavior location data associated with the set of smoking behavior record data, wherein the prompt range includes consecutive areas or spaces that are connected and further includes locations indicated by the resp

Abstract: A device includes a handle including a mount surface, and a display unit rotatably arranged at the mount surface and reversibly switchable between a first state and a second state. The display unit includes a display surface perpendicular to a rotation axis of the display unit. The display surface faces away from the mount surface in both the first state and the second state. A dimension of the display unit in the first state along a lateral direction of the handle is smaller than the dimension of the display unit in the second state along the lateral direction of the handle.

Abstract: The invention relates to the field of biomedicine. Specifically, the present invention relates to aptamers against sclerostin and uses thereof, especially uses in the treatment of sclerostin-related diseases such as osteoporosis.

Abstract: An exosomal composition is provided that includes a therapeutic agent encapsulated by an exosome. The therapeutic agent can be a phytochemical agent, a chemotherapeutic agent, or a Stat3 inhibitor. Pharmaceutical compositions that contain the exosomal compositions are also provided. Methods for treating an inflammatory disease or a cancer are further provided and include administering an effective amount of an exosomal composition to a subject in need thereof to thereby treat the inflammatory disorder or the cancer.

Abstract: Provided are methods for modulating gut microbiota in subjects. In some embodiments, the methods include administering to a subject an effective amount of a composition that includes a first edible plant-derived nanoparticle encapsulating an effective amount of RNA. Also provided are methods for preventing and/or treating gut dysbiosis, methods for modulating bacterial growth, methods for modulating inflammatory cytokines, methods for reducing migration of bacterial from the gut to gut-associated bloodstream, and compositions for use in the presently disclosed methods, including pharmaceutical compositions.

Abstract: Provided are compositions that include an isoamyl alcohol (IAA) sequestration agent, wherein the IAA sequestration agent includes an IAA binding moiety. In some embodiments, the IAA binding moiety is a nucleotide sequence or a peptide or polypeptide (e.g., and antibody or a fragment thereof that includes a paratope) to which IAA binds. In some embodiments, the composition further includes comprising a pharmaceutically acceptable carrier, excipient, or diluent, optionally a pharmaceutically acceptable carrier, excipient, or diluent that is pharmaceutically acceptable for use in a human. The presently disclosed subject matter also provides oligonucleotides, optionally further including a tag, and/or the oligonucleotide includes at least one modified base. Also provided are methods for using the same to reduce and/or delay cognitive decline associated with neurodegenerative disease and/or for sequestering isoamyl alcohol (IAA) produced by microbiota in the gut of subjects.

Abstract: Structural variants of 2D polymers and composites thereof are described.

Abstract: Compositions are provided that comprise a microvesicle derived from an edible plant. The microvesicles are coated with a plasma membrane derived from a targeting cell and can further be utilized to encapsulate a therapeutic agent. Methods for treating an inflammatory disorder and/or a cancer are further provided and include the step of administering to a subject an effective amount of a composition that includes a microvesicle coated with a plasma membrane derived from a targeting cell.

Abstract: The present disclosure is directed toward systems, methods, and non-transitory computer-readable media for determining for a folder a file organization score and providing a free flow element based on the file organization score selectable to transition from providing a folder view to providing a free flow view. In some embodiments, the disclosed systems determine the file organization score indicating file organizational patterns associated with content items within the folder. Furthermore, based on receiving an indication of a selection of the free flow element, the disclosed systems transition from providing the folder view of the folder to providing the free flow view depicting graphical representations of the content items. Moreover, the graphical representations of the content items are arranged according to one or more content features associated with the content items.

Abstract: This application provides a stiffener ring and a surface packaging assembly. The stiffener ring is configured to correct warpage of a substrate of the surface packaging assembly. The stiffener ring includes an annular stiffener ring body and an adjustment block that is disposed at a same layer as the stiffener ring body and that is fastened to at least one corner of the stiffener ring body. A coefficient of thermal expansion of the adjustment block is less than a coefficient of thermal expansion of the stiffener ring body. Coordination between the adjustment block and the stiffener ring body alleviates an “M-shape” overpressure phenomenon of a warpage deformation caused by the stiffener ring to the substrate at a high temperature, reduces warpage of the substrate, and improves flatness of the surface packaging assembly.

Abstract: The present invention relates to the field of biomedicine. Specifically, the present invention relates to an aptamer against DKK1 and uses thereof, in particular to uses in the treatment of DKK1-related diseases such as DKK1-related cancer.

Abstract: The present disclosure provides an action camera, a selfie control method and apparatus, a movable platform, and a storage medium. The action camera includes: a camera body; a lens assembly, disposed on one side of the camera body; a first display apparatus, disposed on the same side as the lens assembly of the camera body, where the first display apparatus is configured to display an image obtained by the lens assembly; and a second display apparatus, disposed on another side of the camera body and opposite to the first display apparatus, where the second display apparatus is configured to obtain a touch operation, and generate a control command based on the touch operation to control, according to the control command, displaying performed by the first display apparatus. The action camera controls a front screen through “back-touch” by using a “rear screen”.

Abstract: Embodiments of the present disclosure discloses a method, apparatus, a device, and a storage medium for message processing. The method includes: displaying a received predetermined message in a conversation interface; in response to determining that the current user triggers jumping to a detail interface of the predetermined message and returns to the conversation interface, determining whether a predetermined condition is satisfied; and in response to a determining result that the predetermined condition is satisfied, displaying, in the conversation interface, at least one shortcut operation control corresponding to the predetermined message.

Abstract: Embodiments of the present disclosure provide an interaction method and apparatus, an electronic device, a storage medium, and a computer program product. The method includes: presenting a multimedia player interface, and presenting a break reminder setting window on the multimedia player interface, where the break reminder setting window displays reminder setting options; and obtaining, in response to a setting confirmation in the break reminder setting window, a reminder triggering condition corresponding to a target reminder setting option selected in the break reminder setting window, and closing the break reminder setting window.

Abstract: The present disclosure provides an action camera, a selfie control method and apparatus, a movable platform, and a storage medium. The action camera includes: a camera body; a lens assembly, disposed on one side of the camera body; a first display apparatus, disposed on the same side as the lens assembly of the camera body, where the first display apparatus is configured to display an image obtained by the lens assembly; and a second display apparatus, disposed on another side of the camera body and opposite to the first display apparatus, where the second display apparatus is configured to obtain a touch operation, and generate a control command based on the touch operation to control, according to the control command, displaying performed by the first display apparatus. The action camera controls a front screen through “back-touch” by using a “rear screen”.

Abstract: Provided are methods for modulating gut microbiota in subjects. In some embodiments, the methods include administering to a subject an effective amount of a composition that includes a first edible plant-derived nanoparticle encapsulating an effective amount of RNA. Also provided are methods for preventing and/or treating gut dysbiosis, methods for modulating bacterial growth, methods for modulating inflammatory cytokines, methods for reducing migration of bacterial from the gut to gut-associated bloodstream, and compositions for use in the presently disclosed methods, including pharmaceutical compositions.

Abstract: The invention relates to the field of biomedicine. In particular, the present invention relates to a nucleic acid molecule conjugate with extended in vivo half-life, wherein the nucleic acid molecule is conjugated to a fatty acid and a coumarin derivative. More specifically, the nucleic acid molecule is an aptamer, in particular an aptamer against sclerostin.

Abstract: The present disclosure is directed toward systems, methods, and non-transitory computer-readable media for determining for a folder a file organization score and providing a free flow element based on the file organization score selectable to transition from providing a folder view to providing a free flow view. In some embodiments, the disclosed systems determine the file organization score indicating file organizational patterns associated with content items within the folder. Furthermore, based on receiving an indication of a selection of the free flow element, the disclosed systems transition from providing the folder view of the folder to providing the free flow view depicting graphical representations of the content items. Moreover, the graphical representations of the content items are arranged according to one or more content features associated with the content items.

Abstract: The present disclosure provides a data processing method, apparatus and device and a storage medium.