Patents by Inventor George Khoury

George Khoury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7977345
    Abstract: A compound for modulating kinase activity according to Formula I, or a pharmaceutically acceptable salt thereof, Wherein J1, J2, J3, R2, J4, Z, Ar and R3 are as defined in the specification, compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: July 12, 2011
    Assignee: Exelixis, Inc.
    Inventors: Lynne Canne Bannen, Diva Sze-Ming Chan, Lisa Esther Dalrymple, Vasu Jammalamadaka, Richard George Khoury, James William Leahy, Morrisson B. Mac, Grace Mann, Larry W. Mann, John M. Nuss, Jason Jevious Parks, Yong Wang, Wie Xu
  • Publication number: 20110156115
    Abstract: Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
    Type: Application
    Filed: March 8, 2011
    Publication date: June 30, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Maroun Georges Khoury, Hongyue Liu, Brian Lee, Andrew John Gjevre Carter
  • Publication number: 20110149639
    Abstract: A non-volatile memory cell array and associated method of use. In accordance with various embodiments, the array includes a plurality of programmable resistive sense elements (RSEs) coupled to a shared switching device. The switching device has a common source region and multiple drain regions, each drain region connected to an associated RSE from said plurality of RSEs.
    Type: Application
    Filed: March 1, 2011
    Publication date: June 23, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Andrew John Carter, Maroun Georges Khoury, Yong Lu, Roger Glenn Rolbiecki
  • Patent number: 7961497
    Abstract: Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: June 14, 2011
    Assignee: Seagate Technology LLC
    Inventors: Maroun Georges Khoury, Hongyue Liu, Brian Lee, Andrew John Gjevre Carter
  • Patent number: 7951972
    Abstract: The present invention provides compounds useful for inhibiting the ADAM-10 protein. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological processes. The present invention also comprises pharmaceutical compositions comprising one or more ADAM-10 inhibitors according to the invention in combination with a pharmaceutically acceptable carrier. Such compositions are useful for the treatment of cancer, arthritis, and diseases related to angiogenesis. Correspondingly, the invention also comprises methods of treating forms of cancer, arthritis, and diseases related to angiogenesis in which ADAM-10 plays a critical role. The invention also provides methods for making bis-aryl ether sulfonyl chlorides and ADAM-10 modulators therefrom.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: May 31, 2011
    Assignee: Exelixis, Inc.
    Inventors: S. David Brown, Lynne Canne-Bannen, Erick Wang Co, Vasu Jammalamadaka, Rickard George Khoury, Moon Hwan Kim, Donna T. Le, Amy Lew Tsuhako, Morrison B. Mac, Shumeye Mamo, John M. Nuss, Michael P. Prisbylla, Wei Xu
  • Patent number: 7935619
    Abstract: Methods of forming polarity dependent switches for resistive sense memory are described. Methods for forming a memory unit include implanting dopant material more heavily in a source contact than a bit contact of a semiconductor transistor, and electrically connecting a resistive sense memory cell to the bit contact. The resistive sense memory cell is configured to switch between a high resistance state and a low resistance state upon passing a current through the resistive sense memory cell.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: May 3, 2011
    Assignee: Seagate Technology LLC
    Inventors: Chulmin Jung, Maroun Georges Khoury, Yong Lu, Young Pil Kim
  • Patent number: 7936583
    Abstract: Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: May 3, 2011
    Assignee: Seagate Technology LLC
    Inventors: Maroun Georges Khoury, Hongyue Liu, Brian Lee, Andrew John Gjevre Carter
  • Patent number: 7933136
    Abstract: A non-volatile memory cell array and associated method of use. In accordance with various embodiments, the array includes a plurality of programmable resistive sense elements (RSEs) coupled to a shared switching device. The switching device has a common source region and multiple drain regions, each drain region connected to an associated RSE from said plurality of RSEs.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 26, 2011
    Assignee: Seagate Technology LLC
    Inventors: Andrew John Carter, Maroun Georges Khoury, Yong Lu, Roger Glenn Rolbiecki
  • Publication number: 20110077233
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate, and/or modulate kinase receptor, particularly c-Met, KDF, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.
    Type: Application
    Filed: October 25, 2010
    Publication date: March 31, 2011
    Applicant: Exelixis, Inc.
    Inventors: Lynne Canne Bannen, Diva Sze-Ming Chan, Jeff Chen, Lisa Esther Dalrymple, Timothy Patrick Forsyth, Tai Phat Huynh, Vasu Jammalamadaka, Richard George Khoury, James William Leahy, Morrison B. Mac, Grace Mann, Larry W. Mann, John M. Nuss, Jason Jevious Parks, Craig Stacy Takeuchi, Yong Wang, Wei Xu
  • Publication number: 20110058404
    Abstract: Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
    Type: Application
    Filed: November 12, 2010
    Publication date: March 10, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Maroun Georges Khoury, Hongyue Liu, Brian Lee, Andrew John Gjevre Carter
  • Publication number: 20110032748
    Abstract: A memory unit includes a resistive sense memory cell configured to switch between a high resistance state and a low resistance state upon passing a current through the resistive sense memory cell and a semiconductor transistor in electrical connection with the resistive sense memory cell. The semiconductor transistor includes a gate element formed on a substrate. The semiconductor transistor includes a source contact and a bit contact. The gate element electrically connects the source contact and the bit contact. The resistive sense memory cell electrically is connected to the bit contact. The source contact is more heavily implanted with dopant material then the bit contact.
    Type: Application
    Filed: October 13, 2010
    Publication date: February 10, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Chulmin Jung, Maroun Georges Khoury, Yong Lu, Young Pil Kim
  • Publication number: 20110026307
    Abstract: Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
    Type: Application
    Filed: October 14, 2010
    Publication date: February 3, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Maroun Georges Khoury, Hongyue Liu, Brian Lee, Andrew John Gjevre Carter
  • Publication number: 20110007543
    Abstract: A resistive sense memory apparatus includes a bipolar select device having a semiconductor substrate, a plurality of collector contacts disposed in a first side of the of the semiconductor substrate, an emitter contact layer disposed in a second side of the semiconductor substrate, and a base layer separating the plurality of collector contacts from the emitter contact layer. Each collector contact is electrically isolated from each other. A resistive sense memory cells is electrically coupled to each collector contacts and a bit line. The base layer and the emitter contact layer provide an electrical path for the plurality of collector contacts.
    Type: Application
    Filed: July 7, 2009
    Publication date: January 13, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventor: Maroun Georges Khoury
  • Publication number: 20110007547
    Abstract: A semiconductor device for accessing non-volatile memory cell is provided. In some embodiments, the semiconductor device has a vertical stack of semiconductor layers including a source, a drain, and a well. An application of a drain-source bias voltage to the semiconductor device generates a punchthrough mechanism across the well to initiate a flow of current between the source and the drain.
    Type: Application
    Filed: July 13, 2009
    Publication date: January 13, 2011
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Maroun Georges Khoury, Hyung-Kyu Lee, Peter Nicholas Manos, Chulmin Jung, YoungPil Kim
  • Patent number: 7825478
    Abstract: Polarity dependent switches for resistive sense memory are described. A memory unit includes a resistive sense memory cell configured to switch between a high resistance state and a low resistance state upon passing a current through the resistive sense memory cell and a semiconductor transistor in electrical connection with the resistive sense memory cell. The semiconductor transistor includes a gate element formed on a substrate. The semiconductor transistor includes a source contact and a bit contact. The gate element electrically connects the source contact and the bit contact. The resistive sense memory cell electrically connects to the bit contact. The source contact and the bit contact are asymmetrically implanted with dopant material.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: November 2, 2010
    Assignee: Seagate Technology LLC
    Inventors: Chulmin Jung, Maroun Georges Khoury, Yong Lu, Young Pil Kim
  • Publication number: 20100210095
    Abstract: Methods of forming polarity dependent switches for resistive sense memory are described. Methods for forming a memory unit include implanting dopant material more heavily in a source contact than a bit contact of a semiconductor transistor, and electrically connecting a resistive sense memory cell to the bit contact. The resistive sense memory cell is configured to switch between a high resistance state and a low resistance state upon passing a current through the resistive sense memory cell.
    Type: Application
    Filed: May 5, 2010
    Publication date: August 19, 2010
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Chulmin Jung, Maroun Georges Khoury, Yong Lu, Young Pil Kim
  • Publication number: 20100117160
    Abstract: Polarity dependent switches for resistive sense memory are described. A memory unit includes a resistive sense memory cell configured to switch between a high resistance state and a low resistance state upon passing a current through the resistive sense memory cell and a semiconductor transistor in electrical connection with the resistive sense memory cell. The semiconductor transistor includes a gate element formed on a substrate. The semiconductor transistor includes a source contact and a bit contact. The gate element electrically connects the source contact and the bit contact. The resistive sense memory cell electrically connects to the bit contact. The source contact and the bit contact are asymmetrically implanted with dopant material.
    Type: Application
    Filed: March 20, 2009
    Publication date: May 13, 2010
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Chulmin Jung, Maroun Georges Khoury, Yong Lu, Young Pil Kim
  • Publication number: 20100118589
    Abstract: A non-volatile memory cell array and associated method of use are disclosed. In accordance with various embodiments, the array includes a plurality of programmable resistive sense elements (RSEs) coupled to a shared switching device. The switching device has a common source region and multiple drain regions, each drain region connected to an associated RSE from said plurality of RSEs.
    Type: Application
    Filed: April 15, 2009
    Publication date: May 13, 2010
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Andrew John Carter, Maroun Georges Khoury, Yong Lu, Roger Glenn Rolbiecki
  • Publication number: 20100110756
    Abstract: Variable resistive punchthrough access methods are described. The methods include switching a variable resistive data cell from a high resistance state to a low resistance state by passing a write current through the magnetic tunnel junction data cell in a first direction. The write current is provided by a transistor being electrically coupled to the variable resistive data cell and a source line. The write current passes through the transistor in punchthrough mode.
    Type: Application
    Filed: October 30, 2008
    Publication date: May 6, 2010
    Applicant: SEAGATE TECHNOLOGY LLC
    Inventors: Maroun Georges Khoury, Hongyue Liu, Brian Lee, Andrew John Gjevre Carter
  • Publication number: 20100105953
    Abstract: The present invention provides compounds useful for inhibiting the ADAM-10 protein, with selectivity versus MMP-1. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological processes. The present invention also comprises pharmaceutical compositions comprising one or more ADAM-10 inhibitors according to the invention in combination with a pharmaceutically acceptable carrier. Such compositions are useful for the treatment of cancer, arthritis, and diseases related to angiogenesis. Correspondingly, the invention also comprises methods of treating forms of cancer, arthritis, and diseases related to angiogenesis in which ADAM-10 plays a critical role.
    Type: Application
    Filed: October 23, 2009
    Publication date: April 29, 2010
    Applicant: Symphony Evolution, Inc.
    Inventors: Lynne Canne Bannen, Erick W. Co, Vasu Jammalamadaka, John M. Nuss, Moon Hwan Kim, Donna Tra Le, Amy Lew, Morrison B. Mac, Shumeye Mamo, Zhaoyang Wen, Wei Xu, Richard George Khoury