Patents by Inventor Guoqing Zhang

Guoqing Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12295269
    Abstract: A low-cost and high-strength Bi-based superconducting wire/tape and a preparation method thereof, the preparation method includes: 1. subjecting a first Bi-based superconducting wire/tape to electrochemical silver reduction to remove a Ag alloy layer to obtain a second Bi-based superconducting wire/tape; and 2. subjecting the second Bi-based superconducting wire/tape to surface enhancement, such that a Cu layer is formed to obtain the low-cost and high-strength Bi-based superconducting wire/tape. An electrochemical silver reduction technology combines with an electrochemical additive method to remove a Ag alloy layer on a surface of a Bi-based superconducting wire/tape and coat a high-strength Cu layer, such that a low-cost and high-strength Bi-based superconducting wire/tape can be prepared, which reduces a preparation cost and improves a strength of a Bi-based superconducting wire/tape to meet the application requirements of large super-strong magnets.
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: May 6, 2025
    Assignee: NORTHWEST INSTITUTE FOR NONFERROUS METAL RESEARCH
    Inventors: Qingbin Hao, Jianfeng Li, Shengnan Zhang, Lihua Jin, Xiaoyan Xu, Gaofeng Jiao, Kai Yao, Chengshan Li, Guoqing Liu, Zhenbao Li, Xueqian Liu, Gaoshan Li, Jianqing Feng, Pingxiang Zhang
  • Publication number: 20250134983
    Abstract: A viral vector delivery system for both respiratory and digestive tracts of pigs and an application thereof are provided. The viral vector delivery system includes a backbone plasmid and a helper plasmid. The backbone plasmid is produced by inserting a full-length cDNA of porcine enterovirus B (PEVB) into a pUC57 plasmid. The helper plasmid is produced by inserting a green fluorescent protein-coding gene into a plasmid pCAG-T7-polymerase. The viral vector delivery system can be constructed with high efficiency, can quickly cause a cytopathic effect (CPE) after infecting cells, has a viral titer up to 107.75 TCID50/mL, and can maintain high stability. A pathogenic epitope for the respiratory and digestive tracts of pigs is inserted into the backbone plasmid to produce a vaccine antigen, which is non-pathogenic, has high stability and a high viral titer, and allows a prominent immunization effect after being inoculated in pigs.
    Type: Application
    Filed: January 8, 2025
    Publication date: May 1, 2025
    Applicants: JIANGSU ACADEMY OF AGRICULTURAL SCIENCES, SNU R&DB FOUNDATION, GUOTAI (TAIZHOU) CENTER OF TECHNOLOGY INNOVATION FOR VETERINARY BIOLOGICALS, TAIZHOU
    Inventors: Xing XIE, Zhixin FENG, Daesub SONG, Rong CHEN, Fei HAO, Lulu XU, Minjoo YEOM, Jongwoo LIM, Lei ZHANG, Yuan GAN, Long ZHAO, Wenliang LI, Qiyan XIONG, Yongjie LIU, Beibei LIU, Yanfei YU, Yun BAI, Guoqing SHAO
  • Publication number: 20250140623
    Abstract: A high-temperature wide-bandgap power module and a preparation method thereof is provided in the present application. In the high-temperature wide-bandgap power module, SiC power chips are arranged in the cavity, and bonding wires are used to establish electrical connections. An ultrathin composite conformal coating consists of inorganic film and Parylene-HT film is arranged on the surface of the circuit to provide long-term reliable insulation while only imposing minor thermo-mechanical stresses on bonding joint at high-temperatures, which prolongs the module's life time. In addition, the hermetic sealing adopted in the present application blocks the external water, oxygen and chemical pollution, thereby alleviating the thermal degradation of the conformal coating and safeguards the internal circuit. Overall, the hermetic sealing and conformal coating ensure the long-term 250 degrees high-temperature working capability of the wide-bandgap power module.
    Type: Application
    Filed: December 27, 2023
    Publication date: May 1, 2025
    Applicant: Huazhong University of Science and Technology
    Inventors: Zhiqiang WANG, Yunchan WU, Rong ZHANG, Guoqing XIN, Xiaojie SHI
  • Publication number: 20250131940
    Abstract: A data-driven audio codec system that involves producing multiple compressed streams comprising encoded information (e.g., codeword indices) at different time scales (time intervals or frequency). This may allow for separation of different properties of speech, such as content and aspects of style (prosody), into the different compressed streams without explicitly enforcing it, i.e., in an unsupervised manner. Speech audio is encoded to produce a plurality of encoded streams comprising encoded information for the speech audio at different time scales. The plurality of encoded streams are decoded to generate output audio.
    Type: Application
    Filed: December 14, 2023
    Publication date: April 24, 2025
    Inventors: Rafal Pilarczyk, Amir Salah Abdelsamie Abdelwahed, Hui-Ling Lu, Ivana Balic, Yusuf Ziya Isik, David Guoqing Zhang, Xuehong Mao, Samer Lutfi Hijazi
  • Patent number: 12272082
    Abstract: The disclosed method includes acquiring sample models and marking sample feature points; selecting target feature points and regional points on bones; transforming the target feature points and the regional points, and registering the target feature points with the sample feature points; formulating a strategy for assigning impact factors to the sample models, linearly combining all sample models to construct an initial model, and determining initial feature points corresponding to the target feature points in the initial model; adjusting the strategy according to the distance between initial feature points and the target feature points, selecting the strategy corresponding to the minimum distance as an optimal strategy, and determining an optimal initial model; determining a matching point corresponding to each regional point in the optimal initial model, and calculating a transformation relationship; and transmitting all points of the optimal initial model according to the transformation relationship to obt
    Type: Grant
    Filed: March 13, 2024
    Date of Patent: April 8, 2025
    Assignees: Vostro Medical Technology (Tianjin) Co., Ltd, The Fourth Medical Center of PLA General Hospital
    Inventors: Mingjun Fu, Wei Chai, Yuan Zhang, Mingmin Ren, Guoqing Yu, Linshuai He, Mingcheng Shen, Zhongwei Wang, Chengcheng Shang
  • Patent number: 12264134
    Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: April 1, 2025
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Dane Clausen, Ping Chen, Xavier Fradera, Liangqin Guo, Yongxin Han, Shuwen He, Xianhai Huang, Joseph Kozlowski, Guoqing Li, Theodore A. Martinot, Alexander Pasternak, Andreas Verras, Li Xiao, Feng Ye, Wensheng Yu, Rui Zhang
  • Publication number: 20250087215
    Abstract: Presented herein are techniques in which a device detecting a phrase spoken in an online collaboration session between a plurality of users, the phrase being spoken by a first user to one or more second users. The device determines that the phrase indicates an issue with a quality of user experience of the online collaboration session, labels a log of metrics associated with the online collaboration session with a time stamp corresponding to a time when the phrase was spoken; and performs one or more actions to improve the user experience based on detecting the phrase.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 13, 2025
    Inventors: Ali Mouline, Christopher Rowen, David Guoqing Zhang, Francis Anthony Kurupacheril
  • Publication number: 20250074964
    Abstract: The disclosure described herein provides for enzymatically stable and potent GLP-1 analogs (i.e., derivatives) for the treatment of metabolic disease or disorder in a subject. In some embodiments, the GLP-1 analog is a derivatized GLP-1 peptide, wherein the derivatized peptide has 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10 amino acid differences from any one of GLP-1, GLP-1(7-39), GLP-1(7-36), GLP-1(7-37). In certain embodiments, the GLP-1 analog comprises at least one lysine substituent. The GLP-1 analogs described herein demonstrate potent receptor binding and extended plasma half-life. A pharmaceutical composition of the GLP-1 analogs is described herein for the treatment of metabolic disease or disorder in a subject, such as diabetes or obesity.
    Type: Application
    Filed: September 5, 2024
    Publication date: March 6, 2025
    Inventors: Juncai BAI, Guoqing ZHANG, Fuliang ZHANG, Michael William PENNINGTON, Simrat P. SINGH
  • Publication number: 20250065815
    Abstract: The present application discloses a base station for mounting vehicle accessories. The base station includes a first guide rail, a second guide rail and a mounting portion. The first guide rail and the second guide rail are mounted on the back side of the vehicle-mounted display screen, and the second guide rail is connected to the first guide rail; the first guide rail and the second guide rail are used to mount multiple vehicle accessories at the same time, the mounting portion is connected to at least one of the first guide rail and the second guide rail, the first guide rail and the second guide rail are fixed to the vehicle-mounted display screen via the mounting portion. The base station for mounting vehicle accessories of the present application can reduce damage to the vehicle-mounted display screen caused by the mounting of vehicle accessory.
    Type: Application
    Filed: November 23, 2023
    Publication date: February 27, 2025
    Inventors: SHUAI ZHANG, ZHIQIANG ZHAO, CHANGJIANG LIU, LIWEI CHEN, GUOQING SUN
  • Patent number: 12230262
    Abstract: Presented herein are techniques in which a device detecting a phrase spoken in an online collaboration session between a plurality of users, the phrase being spoken by a first user to one or more second users. The device determines that the phrase indicates an issue with a quality of user experience of the online collaboration session, labels a log of metrics associated with the online collaboration session with a time stamp corresponding to a time when the phrase was spoken, to provide a labeled log of metrics; and performs one or more actions to improve the user experience based on detecting the phrase.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: February 18, 2025
    Assignee: CISCO TECHNOLOGY, INC.
    Inventors: Ali Mouline, Christopher Rowen, David Guoqing Zhang, Francis Anthony Kurupacheril
  • Publication number: 20250051002
    Abstract: A variable-diameter blade suitable for a trans-media aircraft. The blade is divided into a blade root section, telescopic sections, and a blade tip section in a direction from the root to the tip. The blade further includes a telescopic rod, the blade root section and the blade tip section are fixed to the telescopic rod, respectively, and the telescopic rod is fixed to the trans-media aircraft; a spring arranged in the telescopic rod, the spring is used to drive the telescopic rod to extend; a pulley installed on the trans-media aircraft, the pulley is closer to the blade root section; a pull rope, an end of the pull rope passes through an inside of the blade and is fixed to the blade tip section, and the other end of the pull rope is wound on the pulley; and a driving device for driving the pulley to rotate.
    Type: Application
    Filed: August 9, 2024
    Publication date: February 13, 2025
    Inventors: Xi CHEN, Qijun ZHAO, Fan YANG, Muyang LIN, Guoqing ZHAO, Xiayang ZHANG, Bo WANG, Kaixuan HUANG
  • Publication number: 20250052792
    Abstract: Optical calculation method and system for relay protection based on Faraday magneto-optical rotation effect are provided. A cascaded optical computing approach is employed, where three optical current transformers are connected in series on a single optical path. Final output optical signal represented as a cascaded multiplication of outputs of three optical current transformers, carries a Faraday rotation angle containing differential current information. Differential current required for protection is computed by modulation ratio which is calculated by use of a carrier and modulation wave signals of the output optical signal detecting by filtering circuit from the third optical current transformer.
    Type: Application
    Filed: November 22, 2023
    Publication date: February 13, 2025
    Applicant: HARBIN INSTITUTE OF TECHNOLOGY
    Inventors: Caiyun MO, Guoqing ZHANG, Wenbin YU, Yuxin ZHANG, Ying XU, Zhizhong GUO
  • Patent number: 12222374
    Abstract: Optical calculation method and system for relay protection based on Faraday magneto-optical rotation effect are provided. A cascaded optical computing approach is employed, where three optical current transformers are connected in series on a single optical path. Final output optical signal represented as a cascaded multiplication of outputs of three optical current transformers, carries a Faraday rotation angle containing differential current information. Differential current required for protection is computed by modulation ratio which is calculated by use of a carrier and modulation wave signals of the output optical signal detecting by filtering circuit from the third optical current transformer.
    Type: Grant
    Filed: November 22, 2023
    Date of Patent: February 11, 2025
    Assignee: HARBIN INSTITUTE OF TECHNOLOGY
    Inventors: Caiyun Mo, Guoqing Zhang, Wenbin Yu, Yuxin Zhang, Ying Xu, Zhizhong Guo
  • Publication number: 20250045899
    Abstract: The present invention discloses to a selective-laser-melting (SLM) printing defect detection and repair method and system based on a deep learning network and belongs to the technical field of additive manufacturing.
    Type: Application
    Filed: October 16, 2024
    Publication date: February 6, 2025
    Inventors: Fang Dong, Zihan Yang, Xiangyu Lu, Junlai Zhao, Guoqing Zhang, Yongzhen Jia
  • Publication number: 20250042867
    Abstract: The present invention relates to a process for producing succinic anhydride by maleic anhydride hydrogenation, comprising (1) feeding a maleic anhydride solution and a hydrogen raw material respectively to a first-stage hydrogenation reactor from an upper liquid-phase feed port and a top gas-phase feed port of the first-stage hydrogenation reactor for a first-stage hydrogenation reaction to obtain a first-stage hydrogenation product; (2) feeding the first-stage hydrogenation product to a second-stage hydrogenation reactor for a second-stage hydrogenation reaction to obtain a second-stage hydrogenation product, optionally, before entering the second-stage hydrogenation reactor, subjecting the first-stage hydrogenation product to a first-stage gas-liquid separation to obtain a first-stage gas phase and a first-stage liquid phase, and then feeding the first-stage gas phase and the first-stage liquid phase respectively from a top gas-phase feed port and an upper liquid-phase feed port of the second-stage hydrogen
    Type: Application
    Filed: October 21, 2022
    Publication date: February 6, 2025
    Inventors: Changjiang WU, Guoqing WANG, Dongfeng LI, Liang GUO, Lijun ZHANG, Yan LI, Hui PENG, Shujuan LUO, Jun TIAN, Huimin SHI, Yuehui ZHU, Dongshun ZHANG, Jieming YE, Chunfang LI, Shuliang LU, Yang XU, Qian SHI
  • Patent number: 12209931
    Abstract: Provided is a leakage monitoring device for a pneumatic drain valve of a steam turbine. The disclosure relates to the technical field of leakage monitoring of drain valve. The device includes an additional valve body, a top flange of the additional valve body is provided with an additional sealing cover, a bucket is installed in a middle of an inner side of the additional valve body, an upper part of a left side of an outer surface of the additional valve body is fixedly connected with a water inlet pipe, a first guide cavity is vertically arranged on the inner side of the additional valve body and close to the water inlet pipe and is communicated with the water inlet pipe.
    Type: Grant
    Filed: July 10, 2024
    Date of Patent: January 28, 2025
    Assignee: HUANENG TAIYUAN DONGSHAN GAS TURBINE COGENERATION CO., LTD.
    Inventors: Guoqing Hu, Qinglong Kong, Jiajia Xu, Qiang Han, Xiaochao Zhang
  • Patent number: 12176226
    Abstract: A method for temperature control includes: acquiring the present temperature of a reaction window in a process chamber of a semiconductor machine; comparing the present temperature with the preset temperature to acquire a comparison result; and adjusting the exhaust amount of an exhaust passage of the process chamber based on the comparison result to control the temperature of the reaction window.
    Type: Grant
    Filed: January 12, 2022
    Date of Patent: December 24, 2024
    Assignee: CHANGXIN MEMORY TECHNOLOGIES, INC.
    Inventors: Guoqing Zhang, Su Yang, Duocai Sun, Xingfeng Hong, Yiqun Li
  • Patent number: 12146003
    Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.
    Type: Grant
    Filed: November 16, 2023
    Date of Patent: November 19, 2024
    Assignee: Bausch Health Ireland Limited
    Inventors: Kunwar Shailubhai, Stephen Comiskey, Rong Feng, Juncai Bai, Ruoping Zhang, Jun Jia, Junfeng Zhou, Qiao Zhao, Guoqing Zhang
  • Publication number: 20240370002
    Abstract: The present invention, belonging to the technical field of additive manufacturing, discloses a deep-learning-based SLM (Selective Laser Melting) online quality monitoring and repairing methods and a deep-learning-based SLM (Selective Laser Melting) online quality monitoring and repairing system. The deep-learning-based SLM (Selective Laser Melting) online quality monitoring method comprises: designing and printing a first defective part; collecting monitoring data of a molten pool of the first defective part in the printing process and performing pre-processing; acquiring defect information distribution of the first defective part and constructing a first data set; training a first convolution neural network model through the first data set; and carrying out online defect information identification on a to-be-tested part by using the trained first convolution neural network model.
    Type: Application
    Filed: July 18, 2024
    Publication date: November 7, 2024
    Inventors: Fang Dong, Xiangyu Lu, Guoqing Zhang, Zihan Yang, Sheng Gao, Sheng Liu
  • Publication number: 20240287137
    Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.
    Type: Application
    Filed: November 16, 2023
    Publication date: August 29, 2024
    Inventors: KUNWAR SHAILUBHAI, Stephen Comiskey, Rong Feng, Juncai Bai, Ruoping Zhang, Jun Jia, Junfeng Zhou, Qiao Zhao, Guoqing Zhang