Abstract: Structures including an optical component and methods of fabricating a structure including an optical component. The structure includes a substrate, an optical component including a waveguide core, and a back-end-of-line stack including a heat spreader layer. The optical component is positioned in a vertical direction between the substrate and the back-end-of-line stack. The waveguide core contains a first material having a first thermal conductivity, and the heat spreader layer contains a second material having a second thermal conductivity that is greater than the first thermal conductivity of the first material.

Abstract: A taste-masking composition for pharmaceutical uses is provided comprising a rho kinase inhibitor, a pharmaceutically acceptable salt thereof, a hydrate thereof, a prodrug thereof, a substituted derivative thereof, or a metabolite thereof, or any combination thereof, the rho kinase inhibitor having a bitter taste and being present at a concentration above a taste threshold concentration. The rho kinase inhibitor can comprise fasudil. The composition further comprises a taste-masking agent that masks the bitter taste. The taste-masking agent can partially or fully mask the bitter taste of the rho kinase inhibitor. The taste-masking agent can comprise one or more agents. The composition can be formulated to treat a neurodegenerative disease, for example one or more symptoms of such diseases such as wandering. A method of treating a neurodegenerative disease using such a composition is also provided. Methods of manufacturing the compositions of the present disclosure are further provided.

Abstract: Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.

Abstract: An example of a system may include a processor and a memory device comprising instructions, which when executed by the processor, cause the processor to: access a patient metric of a subject; use the patient metric as an input to a machine learning algorithm, the machine learning algorithm to search a plurality of neuromodulation parameter sets and to identify a candidate neuromodulation parameter set of the plurality of neuromodulation parameter sets, the candidate neuromodulation parameter set designed to produce a non-regular waveform that varies over a time domain and a space domain; and program a neuromodulator using the candidate neuromodulation parameter set to stimulate the subject.

Abstract: The disclosure relates to a system for evaluating movement of a body of a user. The system may include a video display, one or more digital cameras, and a processor. The processor may control the one or more cameras to generate images of at least the part of the body over a period of time. The processor may estimate a position of a plurality of joints of the body. The processor may receive a selection of a tracked pose, and determine, from the plurality of joints, a set of joints associated with the tracked pose. The processor may generate at least one joint vector connecting joints in the set of joints, and assign, based on changes in the joint vector over the period of time, a form score to a performance of the tracked pose. The processor may then generate a user interface that depicts the form score.

Abstract: A memory device comprising a plurality of memory cells, a memory cell of the plurality of memory cells comprising a phase change material (PM) region and a select device (SD) region in series with the PM region; a first address line and a second address line coupled to the memory cell; and memory controller circuitry to interface with the first address line and the second address line, the memory controller circuitry to encode a state in the memory cell by applying, through the first address line and second address line, a current spike and a programming pulse to the memory cell to cause the PM region to be placed into an amorphous state and the SD region of the memory cell to be placed into a high threshold voltage state.

Abstract: A data storage system can have a hardware interposer connected inline between a plurality of controllers and a plurality of memories. A bus of the hardware interposer may be monitored with a security breach monitor of the hardware interposer to allow a deviation from a predetermined address range to be detected by the security breach monitor, which prompts the security breach monitor to block access through the hardware interposer for a first controller of the plurality of controllers.

Abstract: Systems and methods can improve passenger safety for an Autonomous Vehicle (AV) based on the integration of sensor data captured by the AV's interior and exterior sensors. The AV can determine passenger occupancy data corresponding to where each passenger is detected within the AV by the interior sensors. The AV can determine multiple sets of one or more driving actions that the AV can perform at a future time. The AV can generate crash impact data corresponding to where each passenger is detected from one or more simulated collisions between the AV and one or more objected detected by the exterior sensors when the AV performs one or more sets of driving actions from among the multiple sets. The AV can determine ranked sets of driving actions based on the passenger occupancy data and the crash impact data.

Abstract: Dynamically scaling control plane for ingress services for large numbers of applications with minimal traffic disruption includes receiving an estimate of a number of applications to be executed by multiple clusters implemented by an orchestrator platform. Each cluster includes multiple containers. The multiple clusters implement a centralized controller that control execution of the applications by the multiple clusters. The centralized controller is sharded into a variable number of controllers that collectively control the estimated number of applications based on the estimate of the number of applications and a pre-determined number of applications that each controller can control. Each controller of the variable number of controllers controls an execution of a respective subset of the applications. In response to a change in the number of applications over time, the number of controllers is modified based on a number of applications to be executed by the multiple clusters at any given time.

Abstract: Methods, systems, and devices for wireless communications are described. A transmitting device may determine a phase noise profile and may transmit the phase noise profile to a receiving device. The receiving device may use the phase noise profile and received phase tracking reference signals to more accurately determine phase errors on a wireless channel between the two devices and compensate for the phase noise errors. In examples where the UE transmits the phase noise profile to the base station, the UE may include the phase noise profile in a measurement report or in a radio resource control (RRC) message, among other examples. In examples where the base station transmits the phase noise profile to a UE, the base station may include the phase noise profile in a broadcast message, a unicast message, or an RRC message.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: Systems and methods for providing electrostimulation to a neural target are discussed. An example system comprises an implantable stimulator and a controller. The implantable stimulator can provide burst stimulation comprising a pulse train followed by a pulse-free period. The controller can detect an indication of frequency drift of an intrinsic oscillatory neural activity, and in response to the indication of frequency drift, calibrate a burst stimulation parameter including a burst frequency or a timing for initiating the burst stimulation at a particular phase of an oscillation cycle of the intrinsic oscillatory neural activity. The controller can generate a control signal to the implantable stimulator to generate burst stimulation in accordance with the calibrated burst stimulation parameter.

Abstract: A wireless device (e.g., a UE or a base station) may generate a hybrid symbol including a CP portion, a data portion, and at least one of a header portion or a tail portion. The CP portion may be located at a beginning of the hybrid symbol, and may include one or more CP samples that correspond to a predefined number of samples at an end of the hybrid symbol. The data portion may be located after the header portion or before the tail portion. The header portion may be located after the CP portion, and may include one or more predefined header samples. The tail portion may be located at the end of the hybrid symbol, and may include one or more predefined tail samples. The wireless device may generate a waveform including the generated hybrid symbol. The wireless device may transmit a signal based on the generated waveform.

Abstract: Systems, methods, and apparatus are provided for intelligent cybersecurity processing of a product update. A fetcher application may access an updated version of a software product, a prior version of the product, and a version control system for the product. A malicious software identification engine may process the data using batch or stream processing to identify suspect code and metadata anomalies in the updated version. The engine may decompile executable binary code to obtain source code for the updated version and the prior version. A machine learning engine may receive input from the malicious software identification engine and classify the input using an NER-based machine learning model. Based on output from the machine learning engine, a control dashboard may block installation of a malicious product update.

Abstract: A magnetic field sensor may include a plurality of MTJ elements. Each MTJ element of has a state indicated by a magnetic moment direction of a sensing layer relative to a pinned, reference layer in an absence of an external magnetic field. The plurality of MTJ elements are arranged into two identical sets of at least two MTJ elements, where each MTJ element in each respective set has a different state. The states of the MTJ elements are arranged in a manner to measure the external magnetic field regardless of the direction of the external magnetic field. The MTJ elements include identical layers, and are electrically serially connected.

Abstract: Methods, systems, and devices for wireless communications are described in which control information is transmitted using a single carrier (SC) waveform in time domain blocks without a cyclic prefix (CP). A base station may configure a user equipment (UE) for control information transmissions using a SC waveform without CPs in time domain blocks, and may activate the SC waveform without CPs in time domain blocks based on one or more parameters. The control information may be non-uniformly segmented across two or more time domain blocks or two or more portions of a time domain block. A reference signal, such as a demodulation reference signal, may be transmitted in the time domain blocks, where the reference signals may be distributed evenly or unevenly across the time domain blocks.

Abstract: Methods and systems are disclosed for remote code execution between computing environments having various dissimilarities. Client requests at a source environment lead to calls of various types lacking immediate support within the source environment. Calls are delegated to the target environment, where function schemas, data schemas, or copies of source-side schemas are variously used to reconcile called source-side entities with their target-side counterparts. Inconsistencies between name and data representations and datatypes are also addressed. Serially communicated (JSON) parameters are resolved into required target-side multi-level parameter structures, and vice versa. Expedited bulk data access to/from a database layer is supported. A use case is described for phased migration of a software application. Generic and extensible remote code execution allows rapid migration, adaptation, or deployment of software applications across diverse computing environments.

Abstract: An access point that detects a duplicate address is described. During operation, the access point may receive a request associated with an electronic device, where the request includes an address of the electronic device (such as an IP address). In response, the access point may perform a comparison of the address to stored addresses of one or more electronic devices that are associated with the access point. When the comparison indicates that the address is in use by another electronic device in the one or more electronic devices, the access point may provide a response addressed to the electronic device that indicates that the address is in use. Otherwise, the access point may check with a remainder of a network to see if the address is in use. If the address is in use, the access point may provide the response.

Abstract: Payment authentication using OS-based (operating system-based) and issuer-based authenticator applications is provided. The described authenticator applications perform processes including managing a resource with information about registered users; receiving user identifiable information; authenticating a user using the user identifiable information and the information stored in the resource; upon authenticating the user using the user identifiable information and the information stored in the resource, generating a key tied to existing biometric authentication of the user and mapped to the user identifiable information; and communicating with a support server to provide the key and a notification of a potential transaction.

Abstract: A wireless device (e.g., a UE or a base station) may identify a first subcarrier mapping associated with one or more redundant subcarriers. The one or more redundant subcarriers may correspond to one or more UWs in a UW-OFDM waveform. The wireless device may identify a second subcarrier mapping associated with one or more reference signals. A simultaneous application of the first subcarrier mapping and the second subcarrier mapping may be associated with one or more collisions. The wireless device may modify at least one of the first subcarrier mapping or the second subcarrier mapping to eliminate the one or more collisions. The wireless device may generate the UW-OFDM waveform based on the modified at least one of the first subcarrier mapping or the second subcarrier mapping. The wireless device may transmit a signal based on the generated UW-OFDM waveform.