Abstract: This optical coupler for coupling a plurality of visible light beams having different wavelengths includes: a substrate made of a material different from lithium niobate; and an optical coupling function layer formed on a main surface of the substrate. The optical coupling function layer includes: two multimode-interference-type optical coupling parts; optical-input-side waveguides and an optical-output-side waveguide connected to one multimode-interference-type optical coupling part, and optical-input-side waveguides and an optical-output-side waveguide connected to the other multimode-interference-type optical coupling part. The multimode-interference-type optical coupling parts, the optical-input-side waveguides, and the optical-output-side waveguides are made of a lithium niobate film.

Abstract: A parking mechanism includes an actuator having a manual shaft rotating around the first axis, a flange provided on an outer periphery of the manual shaft, a cam rod having a coupling portion coupled to the flange and a rod body moveable along a second axis orthogonal to the first axis with a movement of the flange, a coil spring attached to the rod body, a cam that is attached to the rod body and moves along the second axis by motion of the rod body transmitting via the coil spring, a pawl member having a meshing portion and operating with a movement of the cam, and a parking gear having a tooth portion with which the meshing portion meshes. The self-holding torque of the actuator is larger than the torque applied to the manual shaft at the time of maximum compression of the coil spring.

Abstract: The present invention relates to a use of compounds having TRPV4 inhibitory activity or pharmaceutically acceptable salts thereof, or pharmaceutical compositions containing them for the manufacture of a medicament for preventing or treating a retinal disease accompanied with blood flow disorder or cell disorder. It also relates to a method for preventing or treating the disease, wherein the method comprises administering the compounds or the pharmaceutical compositions containing them to humans or animals. The compounds, the pharmaceutically acceptable salts thereof, or the pharmaceutical compositions containing them may be used in combination with one or more second active agents. The present invention relates to a pharmaceutical composition and a kit containing a compound having TRPV4 inhibitory activity or a pharmaceutically acceptable salt thereof, which is used for preventing or treating the disease.

Abstract: Provided is a composition useful for preventing and/or treating neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. The composition is for preventing and/or treating a neurodegenerative disorder, and contains, as an active ingredient, a compound represented by the following formula (I): or an isomer thereof, or a salt thereof.

Abstract: A carrier system and method carries an object to an object mounting member provided with an object mounting section. The system includes: a measurement device which obtains information related to a flatness of the object; a carrier member that carries the object; and a controller which controls a driving speed of the carrier member using the information related to the flatness of the object obtained by the measurement device.

Abstract: The present invention provides a novel composition for increasing the retention of a carotenoid in blood. More specifically, a composition for increasing the retention of a carotenoid in blood, the composition comprising one or more asymmetric carotenoids or a pharmaceutically acceptable salt thereof, is used.

Abstract: A carrier system and method carries an object to an object mounting member provided with an object mounting section. The system includes: a measurement device which obtains information related to a flatness of the object; a carrier member that carries the object; and a controller which controls a driving speed of the carrier member using the information related to the flatness of the object obtained by the measurement device.

Abstract: The present invention provides a novel composition for inhibition or treatment of brain tumors or symptoms attributable thereto. More specifically, the present invention provides a composition for inhibition or treatment of brain tumors or symptoms attributable thereto, comprising one or more carotenoids selected from astaxanthin, adonirubin, adonixanthin, zeaxanthin, and a pharmaceutically acceptable salt thereof.

Abstract: A carrier system and method carries a plate-like object to an object mounting section. The system imparts vibration to the object that has been moved such that the object is vibrating when the object is placed onto the mounting section.

Abstract: Provided is a pharmaceutical for preventing or treating an ophthalmic disease associated with intraocular neovascularization and/or increased intraocular vascular permeability. The inventors of the present invention have made investigations on a pharmaceutical for preventing or treating an ophthalmic disease associated with intraocular neovascularization and/or increased intraocular vascular permeability, and have confirmed that a selective S1P receptor agonist having agonist activity at an S1P1 receptor has an intraocular neovascularization-reducing action and an intraocular vascular permeability-reducing action, thus completing the present invention.

Abstract: A carrier system and method carries a plate-like object to an object mounting section. The system imparts vibration to the object that has been moved such that the object is vibrating when the object is placed onto the mounting section.

Abstract: A carrier system and method carries a plate-like object to an object mounting member provided with an object mounting section. The system includes an adjustment device that changes a shape of the plate-like object into a predetermined shape before the plate-like object is mounted onto the object mounting section. The plate-like object whose shape is changed into the predetermined shape is mounted onto the object mounting section.

Abstract: A carrier system and method carries a plate-like object to an object mounting member provided with an object mounting section. The system includes an adjustment device that changes a shape of the plate-like object into a predetermined shape before the plate-like object is mounted onto the object mounting section. The plate-like object whose shape is changed into the predetermined shape is mounted onto the object mounting section.

Abstract: A carrier system and method carries a plate-like object to an object mounting member provided with an object mounting section. The system includes an adjustment device that changes a shape of the plate-like object into a predetermined shape before the plate-like object is mounted onto the object mounting section. The plate-like object whose shape is changed into the predetermined shape is mounted onto the object mounting section.

Abstract: A painting booth includes a pair of first inner surfaces facing each other in a first horizontal direction with a painting treatment area therebetween, an air supply duct arranged at the center, in the first horizontal direction, of the upper part of the inside of the painting booth, and an air blow-out port which is formed ranging from a central part to both side parts, in the first horizontal direction, of the air supply duct and which blows out air right downward at the central part and blows out air in an obliquely downward direction of each of the first inner surfaces on the both side parts.

Abstract: An exposure apparatus includes a projection system having an optical element; a substrate stage which has a holder configured to hold a substrate and which is movable below the projection system; a first nozzle member having a liquid supply port; a second nozzle member having a liquid recovery port which is arranged such that the liquid recovery port faces an upper surface of the substrate during exposure; and a driving system having a motor, which moves the second nozzle member in a direction substantially perpendicular to an optical axis of the optical element. The second nozzle member is moved based on a movement condition of the substrate stage. The substrate is exposed via liquid covering a portion of the upper surface of the substrate. The liquid supply via the liquid supply port is performed parallel to the liquid recovery via the liquid recovery port.

Abstract: An exposure apparatus includes a projection system having an optical element via which an exposure beam is projected; an immersion area forming member having an opening through which the exposure beam is projected, the immersion area forming member having a liquid supply inlet facing downward, a liquid recovery outlet facing downward, and a liquid supply port disposed between the liquid supply inlet and the liquid recovery outlet; a frame by which the projection system and the immersion area forming member are supported; a first vibration isolator by which transmission of vibration from the frame to the projection system is limited; and a second vibration isolator by which transmission of vibration from the immersion area forming member to the frame is limited. A liquid immersion area is formed, using the immersion area forming member, on a portion of an upper surface of a substrate, which is exposed to the exposure beam.

Abstract: A coating booth includes a coating processing area that is provided in the coating booth and in which a workpiece is to be coated with atomized paint and a ceiling part from which air flows downward to remove atomized paint not adhered to the workpiece The ceiling part has an approximately quadrangular planar shape and includes a pair of air delivery units that have band-shaped areas extending along a pair of outer edge parts opposed to each other in the ceiling part, and are configured to deliver air downward, and a normal ceiling part that is provided between the pair of band-shaped areas and is configured not to deliver air. The coating processing area is entirely included in an area vertically below the normal ceiling part. The air delivered from the air delivery units has an air speed of from 0.05 m/s to 0.20 m/s.

Abstract: A painting booth includes a pair of first inner surfaces facing each other in a first horizontal direction with a painting treatment area therebetween and a pair of first inclined ceiling surfaces inclined downward from a position close to a center, in the first horizontal direction, in an upper part of the inside to an upper end part of each of the pair of first inner surfaces. An air supply duct is disposed at a center of the upper part of the inside, and a side air blow-out port is provided on the air supply duct to blow air against the pair of first inclined ceiling surfaces.

Abstract: An exposure apparatus includes a projection system, a stage having a holder on which a substrate is held, a supply system having a supply flow path via which liquid is supplied to form an immersion area under the projection system, a first recovery system having a recovery port via which the supplied liquid is recovered from above the stage, a second recovery system having a recovery flow path provided in the stage via which the supplied liquid is recovered, and a third recovery system which has a path and which removes liquid in the supply flow path using the path. The substrate is exposed via the liquid immersion area covering a portion of an upper surface of the substrate with exposure light from the projection system.