Abstract: The present invention provides preventive, ameliorating, and/or therapeutic agents for diseases caused by a disturbed balance between bone formation and bone resorption. The decoys of the present invention induce normal bone metabolism by inhibiting the differentiation-inducing factors of cells involved in bone metabolism. For example, bone resorption can be controlled by using a decoy of the present invention to inhibit NF-?B, a transcriptional regulatory factor that regulates osteoclast differentiation. This method uses a mechanism different from those of previous pharmaceutical agents; therefore, one can expect it to be effective for cases in which existing pharmaceutical agents were not effective.

Abstract: A walking assistance device comprises a pelvic frame (10) extending from a lower back to each lateral side of a user, and a belly belt (20) for securing the pelvic frame in position. A power generator (30) is attached to each lateral side of the pelvic frame. A power transmitting arm (40) can be attached to an output member (33) of the power generator simply by hooking an upper part of a base end (41) of the power transmitting arm onto an upper groove (38) of the output member, and pushing a latch member or a slider (46) provided in a lower part of the base end onto a lower groove (39) of the output member. Therefore, the user wearing the pelvic frame (10) can easily attach the power transmitting arm (40) to the output end of the power generator (30) by using a single hand with ease and without requiring a help from a caretaker.

Abstract: Sheet-like audio information recording/reproducing means capable of recording/reproducing audio information is sandwiched between two support sheets from front and back only in part of the area thereof and these two support sheets are further sandwiched between two surface sheets and the support sheets and surface sheets are bonded together.

Abstract: A switching power supply has a full-wave AC rectifier circuit; a chopper circuit including an inductor, a capacitor smoothing current from the inductor, and a switching device for on-off control of the current fed to the capacitor. The rectifier circuit further has an input voltage detector circuit detecting chopper circuit input voltage; an output voltage error detector circuit detecting an error between an output voltage from the chopper circuit and a set voltage; a current control signal generator circuit generating a current control signal in-phase with an input voltage detection signal having a waveform similar to the input voltage detection signal and an amplitude proportional to an output voltage error signal; a current detector circuit detecting inductor current flow; a frequency setting circuit; an oscillator circuit; and a switching control circuit switching the switching device based on oscillation circuit signal, the current control signal, and the current detection signal.

Abstract: A guanidine compound having a biaryl skeleton represented by the following formula (1), which is useful as a catalyst for various asymmetric reactions.

Abstract: A cache controller is connected to a processor and a main memory. The cache controller is also connected to a cache memory that can read and write at a speed higher than the main memory. The cache memory is provided with a plurality of cache lines that include a tag area storing an address on the main memory, a capacity area storing a capacity value of a cache block, and a cache block. When a read request is executed from the processor to the main memory, the cache controller checks whether the requested data is present in the cache memory or not. A cache capacity determination unit determines a capacity value for the cache block and supplies to a capacity area.

Abstract: Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity.

Abstract: Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity.

Abstract: In a switching power supply apparatus, multiplier 9 multiplies error voltage Verr generated in voltage error amplifier 8 and input voltage Vin to generate first threshold signal Vth1 in-phase with and similar to input voltage Vin and having an amplitude proportional to error voltage Verr. Second threshold signal generator circuit 14 generates second threshold signal Vth2 from first threshold signal Vth1. Switching device 7 is turned on and off so that the inductor current may change between first and second threshold signals Vth1 and Vth2. The switching frequency is detected and the proportional factor of first and second threshold signals Vth1 and Vth2 is changed to control the average switching frequency almost at a constant value for reducing the high frequency noises and the switching losses. The switching power supply apparatus facilitates reducing the noises and losses, improving the power factor thereof, and preventing the response performances thereof from being impaired.

Abstract: The power source contains a plurality of batteries stacked in more than three tiers within a battery case divided into a first sub holder case and second sub holder case, and the first sub holder case contains the batteries in a larger number of tiers than the second sub holder case. An intermediary duct is provided between the two sub holder cases, and a first outer duct and a second outer duct are respectively provided outside each of the two sub holder cases. The batteries in the holder case are cooled by the cooling air which flows from the intermediary duct through the holder case into the outer duct for exhaustion. Further, the second outer duct is designed to experience a larger pressure loss than the first outer duct.

Abstract: By suppressing transcription activation by NF?B, the present invention was demonstrated to suppress alveolar bone resorption in periodontal disease models, and promote restoration of alveolar bone in periodontal disease-caused bone defect models. Therefore, the present invention provides agents for treating, preventing, and improving periodontal diseases and alveolar bone defects caused by surgical operations, said agents comprising as an active ingredient, a NF?B decoy or such that suppresses the transcription activity of NF?B.

Abstract: An error voltage Verr, being a difference between DC output voltage Vout and output reference voltage Vref, and an input voltage Vin are multiplied to produce first threshold voltage signal Vth1 in phase with and similar to input voltage Vin and proportional to Verr. Second threshold voltage signal Vth2 is produced from first threshold voltage signal Vth1. The input current is detected as a current detection signal Vi across a resistor 12, whether it is between the threshold value signals is detected by a current range detecting circuit, and accordingly, the timing of turning on or off switching device is controlled so that at least one of an duration on and an off duration of the switching device is limited to enhance a power factor. Unfixed off duration disperses a noise spectrum to prevent an increase in switching frequency, to reduce noise.

Abstract: According to an aspect of the invention, Montgomery arithmetic can be achieved while omitting division in an input stage. That is, the aspect of the invention is configured to obtain a Montgomery transform result m? (=mR mod p) of n-bit from an input m of 2n-bit without using the division, with using Montgomery reduction and Montgomery multiplication instead of conventional mod arithmetic and the Montgomery transform. Accordingly, Montgomery arithmetic can be achieved while omitting the division in the input stage.

Abstract: An electric power source used with a vehicle includes: a battery block composed of a rechargeable battery; a cooling plate thermally coupled with the battery block to cool the battery; a cooling mechanism for cooling the cooling plate; and a controller for controlling the cooling mechanism to switch the cooling plate into a cooled state and an uncooled state. The controller controls the cooling mechanism both in accordance with temperature of the battery block and temperature of the cooling plate, and switches the cooling plate into the cooled state and the uncooled state.

Abstract: Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity.

Abstract: A battery system includes a battery block, a cooling pipe, and a coolant feeding device. The battery block includes a plurality of rectangular batteries that have a width greater than a thickness and are securely arranged in array alignment by a battery holder. The cooling pipe cools the rectangular batteries of the battery block. The coolant feeding device feeds coolant to the cooling pipe. In the battery system, the cooling pipe is arranged on the surface of the battery block in a thermally-coupled state so that the rectangular batteries are cooled by the coolant, which is circulated through the cooling pipe.

Abstract: The battery system cooled via coolant has a battery block 3 with a plurality of rectangular batteries 1 retained in a stacked configuration by a battery holder 4; a cooling plate 8 disposed in thermal contact with the bottom surface of the battery block 3 and having a hollow region 18 inside; cooling pipe 6 disposed inside the hollow region 18 of the cooling plate 8; and a coolant supply device 7 to supply coolant to the cooling pipe 6. The hollow cooling plate 8 has a surface plate 8A that makes thermal contact with the bottom surface of the battery block 3, and cooling pipe 6 is disposed within the hollow region 18 in contact with the inside of the surface plate 8A. Further, the cooling plate 8 hollow region 18 is filled with plastic foam 9.

Abstract: A battery system includes: a battery block defining a cooling gap between battery cells composed of a plurality of rectangular/prismatic cells; and a gas blower forcibly blowing the gas through the gap in the block. The block, set in two separate arrays, is provided therebetween with an intermediate duct connected to each of the gaps. An outer duct is provided outside the block set in two separate arrays, and the plurality of gaps are parallel-connected between the outer duct and the intermediate duct. The gas blower forcibly blows the gas from the intermediate duct to the outer duct, and the gas forcibly blown is branched from the intermediate duct to be blown through each of the gaps to cool the cells. The gas having passed through the gaps and cooled the cells is collected at and exhausted from the outer duct.

Abstract: A cache controller is connected to a processor and a main memory. The cache controller is also connected to a cache memory that can read and write at a speed higher than the main memory. The cache memory is provided with a plurality of cache lines that include a tag area storing an address on the main memory, a capacity area storing a capacity value of a cache block, and a cache block. When a read request is executed from the processor to the main memory, the cache controller checks whether the requested data is present in the cache memory or not. A cache capacity determination unit determines a capacity value for the cache block and supplies to a capacity area.

Abstract: A method for treating a bone metabolic disease by administering to a human a pharmacologically effective amount of an angiotensin II receptor antagonist which is a compound of the following formula (I), a pharmacologically acceptable salt thereof or a pharmacologically acceptable ester thereof: wherein R1 represents a C1-C4 alkyl; R2 and R3 are the same or different and each represent hydrogen or a C1-C4 alkyl; R4 represents hydrogen or a C1-C4 alkyl; R5 represents hydrogen, a C1-C4 alkyl, a C2-C5 alkanoyloxymethyl, 1-(C2-C5 alkanoyloxy)ethyl, a C1-C4 alkoxycarbonyloxymethyl, 1-(C1-C4 alkoxycarbonyloxy)ethyl, a (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl, a (5-phenyl-2-oxo-1,3-dioxolen-4-yl)methyl or a phthalidyl; and R6 represents a carboxy or a tetrazole-5-yl.