Patents by Inventor Hiroaki Hayashi

Hiroaki Hayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5219864
    Abstract: Disclosed is a thienopyridine derivative represented by formula (I): ##STR1## wherein one of A and B represents --S-- and the other represents --CH.dbd.; R represents hydrogen or lower alkyl, and Z represents pyridyl; or a pharmaceutically acceptable salt thereof.The thienopyridine derivative is useful as an immunoregulator and for the prevention and treatment of osteoporosis.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: June 15, 1993
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Yoshikazu Miwa, Hiroaki Hayashi, Takeshi Kuroda, Kenji Ohmori, Hiroshi Nakajima
  • Patent number: 5155115
    Abstract: Disclosed is a thienopyridine derivative represented by formula (I): ##STR1## wherein one of A and B represents --S-- and the other represents --CH.dbd.; X represents --O-- or --NH--; R.sup.1 represents hydrogen or lower alkyl; R.sup.2 represents lower alkyl; and n represents 0 or 1; or a pharmaceutically acceptable salt thereof.The thienopyridine derivative is useful as anti-emetics and suppressant of migraine.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: October 13, 1992
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Yoshikazu Miwa, Hiroaki Hayashi, Akio Ishii, Shunji Ichikawa, Ichiro Miki
  • Patent number: 5120737
    Abstract: A hexitol derivative represented by formula (I) ##STR1## wherein R represents hydrogen, unsubstituted or lower alkyl-substituted cycloalkyl, lower alkenyl, lower alkoxy, lower alkanoyl, piperidyl or ##STR2## wherein each of m and n independently represents an integer of 0 to 3; each of X, Y and Z independently represents hydrogen, lower alkyl, lower alkoxy, lower alkanoyl, lower alkanoyloxy, hydroxyl, halogen or nitro or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 24, 1991
    Date of Patent: June 9, 1992
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Hiroaki Hayashi, Kazuhiro Kubo, Junichi Ikeda
  • Patent number: 5102634
    Abstract: A method for purifying an exhaust gas containing catalyst poison(s) by subjecting the gas to a catalytic treatment which comprises previously passing the gas through a layer packed with a highly activated alumina to remove the catalyst poison(s); and an apparatus for purifying exhaust gas containing catalyst poison(s) by subjecting the gas to a catalytic treatment, wherein a layer packed with a highly activated alumina for removal of the catalyst poison(s) and a layer packed with an oxidation catalyst for removal of harmful substances in the gas are separately arranged.
    Type: Grant
    Filed: August 12, 1991
    Date of Patent: April 7, 1992
    Assignee: Nippon Shokubai Kagaky Kogyo Co., Ltd.
    Inventors: Hiroaki Hayashi, Kunio Sano, Yasushi Hattori, Kazuyoshi Nishikawa
  • Patent number: 5053408
    Abstract: Disclosed is a hexitol derivative represented by the formula (I): ##STR1## wherein Q represents a formula selected from the group consisting of ##STR2## wherein a represents NH, O or S;each of b, c and d independently represents CH or N;each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represents hydrogen, lower alkyl, trifluoromethyl, aryl, lower alkanoyloxy, amino, lower alkylamino, lower alkanoylamino, lower alkanoyl, aroyl, halogen, nitro, (CH.sub.2).sub.m OR.sup. 7, (CH.sub.2).sub.m SR.sup.7, (CH.sub.2).sub.m CO.sub.2 R.sup.7 where R.sup.7 represents hydrogen or lower alkyl and m represents an integer of 0 to 3;each of R.sup.5 and R.sup.6 independently represents hydrogen or lower alkyl;U represents >N-- or ##STR3## W represents a single bond, --O-- or --S--; X represents ##STR4## wherein each of Y.sup.1 and Y.sup.2 independently represents hydrogen, lower alkyl, hydroxyl, lower alkanoyloxy, nitrile or phenyl; or Y.sup.1 and Y.sup.2 are combined together to form oxygen;each of Y.sup.3 and Y.
    Type: Grant
    Filed: April 13, 1990
    Date of Patent: October 1, 1991
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Hiroaki Hayashi, Takeshi Kuroda, Kazuhiro Kubo, Junichi Ikeda
  • Patent number: 4934440
    Abstract: A mold surface treatment process comprises: providing a fluidized bed of a treating powder; holding the mold in the fluidized bed to fill up the depressions of the mold surfaces with the treating powder by employing a surface treating member for pushing the treating powder into the depressions; and taking the mold out of the fluidized bed. The mold surface treatment allows to make molten metal less likely penetrate into the walls of mold, and to manufacture a mold which generates less amount of gum causing defects during casting.
    Type: Grant
    Filed: September 1, 1988
    Date of Patent: June 19, 1990
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha
    Inventors: Yuji Sakakibara, Takatoshi Suzuki, Hiroaki Hayashi, Yasuo Takada, Akihiko Suda, Yoshiro Hayashi, Kenji Kaida, Ryuuichi Masuda, Masahiro Taguchi
  • Patent number: 4788583
    Abstract: A semiconductor device has such a construction that free tip ends of stage bars extending from a stage do not extend to side surfaces of a resin package, and the resin package is constituted by an inner resin package portion and an outer resin package portion. The free tip ends of the stage bars are located inside the outer resin package portion and are completely sealed. A method of producing the semiconductor device includes steps of providing wires for electrically connecting terminals of a semiconductor element which is mounted on the stage with corresponding leads and forming the inner resin package portion over the semiconductor element and its vicinity including portions of the leads and stage bars which are connected to the stage.
    Type: Grant
    Filed: July 24, 1987
    Date of Patent: November 29, 1988
    Assignees: Fujitsu Limited, Fujitsu Vlsi Limited
    Inventors: Toshimi Kawahara, Michio Sono, Hiroaki Hayashi
  • Patent number: 4767801
    Abstract: Molding material composed of casting sand coated with a thermosetting resin and hydrous magnesium silicate clay mineral which may be impregnated with an acid and/or coated with a thermosetting resin, and a shell mold produced from the molding material. This material and mold minimize generation of smoke and irritating gases at the time of mold making and casting.
    Type: Grant
    Filed: March 23, 1987
    Date of Patent: August 30, 1988
    Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho
    Inventors: Takatoshi Suzuki, Yasuo Takada, Yuji Sakakibara, Masahiro Sugiura, Hiroaki Hayashi, Osami Kamigaito
  • Patent number: 4691756
    Abstract: Molding material composed of casting sand coated with a thermosetting resin and hydrous magnesium silicate clay mineral which may be impregnated with an acid and/or coated with a thermosetting resin, and a shell mold produced from the molding material. This material and mold minimize generation of smoke and irritating gases at the time of mold making and casting.
    Type: Grant
    Filed: August 14, 1986
    Date of Patent: September 8, 1987
    Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho
    Inventors: Takatoshi Suzuki, Yasuo Takada, Yuji Sakakibara, Masahiro Sugiura, Hiroaki Hayashi, Osami Kamigaito
  • Patent number: 4600437
    Abstract: Inorganic material comprises a mixture of water glass and metakaolin obtained by heat treating a kaolin group clay mineral at 600.degree. to 900.degree. C. This inorganic material, when solidified by drying, exhibits excellent water resistance, and when solidified by heating to a temperature of 80.degree. to 500.degree. C., exhibits excellent water and hot water resistances. The inorganic material may further contain a hydrous magnesium silicate type clay mineral. Such material, when solidified by drying, exhibits further excellent water resistance and when solidified by heating to a temperature of 80.degree. to 500.degree. C., exhibits excellent resistances to water, hot water and boiling water.
    Type: Grant
    Filed: March 26, 1985
    Date of Patent: July 15, 1986
    Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho
    Inventors: Masahiro Sugiura, Yoshiaki Fukushima, Hiroaki Hayashi, Mitsumasa Horii, Takako Kurimoto, Kazuhiro Fukumoto
  • Patent number: 4552806
    Abstract: Heat-insulating cellular glass having a surface on which an adhesive layer and a coating layer are formed. The adhesive layer comprises a solidified mixture of water glass, and a porous substance containing polyvalent ions of metals, such as Ca, Mg, Ba and Al, and the coating layer comprises a laminate of flakes of a laminar mineral. This cellular glass is widely used as a heat-insulating material having an improved thermal shock resistance.
    Type: Grant
    Filed: July 12, 1983
    Date of Patent: November 12, 1985
    Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho
    Inventors: Hiroaki Hayashi, Toshio Kandori, Yoshiaki Fukushima
  • Patent number: 4541503
    Abstract: A four-wheel drive automobile has a driving system which includes a transversely oriented engine unit, a transmission having input and output shafts which extend transversely of the car body, an inter-axle differential gear mechanism, front and rear inter-wheel differential gear mechanisms, and a differential gear lock mechanism. The inter-axle differential gear mechanism, the front inter-wheel differential gear mechanism and the differential gear lock mechanism are arranged coaxially with one another. The differential gear lock mechanism is provided in a part of said inter-axle differential gear mechanism which is positioned at a side of the front differential gear mechanism so that the front differential gear mechanism is located between inter-axle differential gear mechanism and the differential gear lock mechanism.
    Type: Grant
    Filed: September 27, 1983
    Date of Patent: September 17, 1985
    Assignee: Mazda Motor Corporation
    Inventors: Hitoshi Akutagawa, Masayoshi Shigemasa, Hiroaki Hayashi
  • Patent number: 4271310
    Abstract: Cholinesterase activity is determined by means of the choline and/or acid obtained by the action of cholinesterase on a compound of the formula: ##STR1## [wherein A represents a hydrogen atom or a C.sub.1-5 alkyl or alkoxy group and B represents a group of the formula --R-COO-- (in which --R-- represents an alkenyl group with 2 to 6 carbon atoms); or A represents a hydroxy group in either or both o-positions of the benzene ring or a C.sub.1-5 alkyl group and B represents a group of the formula --COO--; X represents a stabilizing anion and n represents the charge on the anion]. The method of the invention ensures a high resistance to saturation, good stability of the compounds used as substrates, a conveniently low reaction rate and a high degree of accuracy.Certain of the compounds of formula I as defined above are novel compounds which are claimed per se.Examples of the method of the present invention are given and the preparation of the novel compounds is described and exemplified.
    Type: Grant
    Filed: April 12, 1979
    Date of Patent: June 2, 1981
    Assignee: Kyowa Hakko Kogyo Kabushiki Kaisha
    Inventors: Katsuyuki Watanabe, Tadatoshi Hayashi, Hiroaki Hayashi, deceased, by Atsuko Hayashi, heir, by Yuko Hayashi, heir, Toshio Tatano, Yoshiaki Shmizu
  • Patent number: 4215234
    Abstract: A natural circulation type evaporative cooling electric power cable line having a circulation system for the cooling medium wherein a cooling medium passage within the electric power cable line has an inlet and an outlet respectively connected with a cooling unit positioned at a level higher than the cooling medium passages inlet of the cable by means of a feeding pipe and a return pipe with a liquefiable gas cooling medium sealed therein. At least a riser portion of the return pipe leading to the cooling unit is installed below the level of the cooling medium return passage outlet of the cable, and the return pipe is provided with a device for boosting circulation force without positive displacement mechanism (such as a pump or the like), so as to make the cooling medium circulate even in a low load current region by exceeding the current allowable without cooling for that cable.
    Type: Grant
    Filed: July 21, 1978
    Date of Patent: July 29, 1980
    Assignees: The Tokyo Electric Power Company, Sumitomo Electric Industries, Ltd.
    Inventors: Hiroaki Hayashi, Kiyoshi Fukuda, Hiroshi Kubo, Noriyasu Yoshikawa, Hiroshi Takada
  • Patent number: 4141792
    Abstract: Phospholipid content in a sample is quantitatively determined by enzymatically converting the phospholipids into choline and then determining the amount of the choline.
    Type: Grant
    Filed: August 17, 1977
    Date of Patent: February 27, 1979
    Inventors: Hiroaki Hayashi, Katsuyuki Watanabe, Toshio Tatano
  • Patent number: 4021255
    Abstract: A beta-alumina polycrystal article permeable to sodium and potassium ions made by sintering .beta.-alumina and tantalum. The article evidences high corrosion resistance against sodium, potassium and their ions, and is especially useful as a solid electrolyte for a sodium-sulfur battery because of its excellent durability.
    Type: Grant
    Filed: February 14, 1975
    Date of Patent: May 3, 1977
    Assignee: Kabushiki Kaisha Toyota Chuo Kenkyusho
    Inventors: Takewo Chiku, Kiyoshi Ninomiya, Takashi Yoshida, Takeshi Kogiso, Hiroaki Hayashi, Noboru Matsui