Patents by Inventor Hirofumi Nakano
Hirofumi Nakano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12133558Abstract: To provide an inhaler cartridge and an inhaler including a novel structure. Provided is a cartridge for an inhaler. The cartridge includes: a housing including an accommodation space capable of accommodating a liquid, an air flow passage, and a partition member partitioning the accommodation space and the air flow passage in a longitudinal direction; and a heater configured to be capable of heating the liquid and arranged in the air flow passage. The partition member includes an opening opened in a transverse direction to bring the accommodation space into communication with the air flow passage. The opening includes an upstream-side opening edge and a downstream-side opening edge. The partition member includes an upstream-side end and a downstream-side end. A distance between the upstream-side opening edge and the upstream-side end is smaller than a distance between the downstream-side opening edge and the downstream-side end.Type: GrantFiled: October 3, 2022Date of Patent: November 5, 2024Assignee: JAPAN TOBACCO INC.Inventors: Tomoichi Watanabe, Hirofumi Matsumoto, Takuma Nakano, Kei Oishi
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Publication number: 20240245094Abstract: According to the present invention, a liquid for atomization includes organic acid ions A, metal ions M, and a medium. The liquid for atomization is to be contained in an atomization device without coming into contact with metal.Type: ApplicationFiled: April 5, 2024Publication date: July 25, 2024Applicant: Japan Tobacco Inc.Inventors: Hirofumi MATSUMOTO, Takuma NAKANO, Hirofumi FUJIKURA, Mai SUGIURA
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Publication number: 20220291146Abstract: A window portion has a membrane that separates a space inside a container and a space outside the container, and a structure (glass structure) that is bonded to the membrane to support the membrane. The membrane and the structure are bonded by anodic bonding, and a chemical bonding layer is formed between them. The structure is composed of a grid having a plurality of openings, and an outer frame around the grid. A metal layer may be provided between the membrane and the structure.Type: ApplicationFiled: March 10, 2022Publication date: September 15, 2022Inventor: Hirofumi Nakano
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Patent number: 11393606Abstract: There is provided a radiation transmissive window having high radiation transmissivity. The radiation transmissive window includes: an outer frame having an opening; a radiation transmissive film closing off the opening; and a grid member that partitions the opening into a plurality of small opening portions. The grid member has a first portion, a second portion at a smaller distance to the center of the opening than the first portion, and a third portion at a smaller distance to the center of the opening than the second portion. The first portion is greater in width than the second portion. The second portion is greater in width than the third portion.Type: GrantFiled: March 24, 2021Date of Patent: July 19, 2022Assignee: JEOL Ltd.Inventor: Hirofumi Nakano
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Publication number: 20210304915Abstract: There is provided a radiation transmissive window having high radiation transmissivity. The radiation transmissive window includes: an outer frame having an opening; a radiation transmissive film closing off the opening; and a grid member that partitions the opening into a plurality of small opening portions. The grid member has a first portion, a second portion at a smaller distance to the center of the opening than the first portion, and a third portion at a smaller distance to the center of the opening than the second portion. The first portion is greater in width than the second portion. The second portion is greater in width than the third portion.Type: ApplicationFiled: March 24, 2021Publication date: September 30, 2021Inventor: Hirofumi Nakano
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Patent number: 11119095Abstract: Provided is a method for measuring tyrosine phosphatase and tyrosine kinase activity, as a high-sensitivity measuring method, which is suitable for high throughput and which uses a compound represented by general formula (I) (in the formula, A represents a conjugated ring; L represents a linker or the like having a labeling substance at an end; R1 represents a hydrogen atom or the like; and R2 and R3 each represent a hydrogen atom, an alkyl group or the like).Type: GrantFiled: September 26, 2016Date of Patent: September 14, 2021Assignee: TOKYO INSTITUTE OF TECHNOLOGYInventors: Shinichi Sato, Hiroyuki Nakamura, Hirofumi Nakano
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Patent number: 10630522Abstract: To reduce a hardware circuit scale and a memory capacity in a communication system reducing a PAPR. A transmitter includes a transmission processing feedback type FIR filter configured to feed back data outputted from the last stage delay element of a plurality of delay elements included in an FIR filter to the first stage delay element and configured to set an initial value to a delay element in a predetermined position, of the delay elements, and performs transmission processing by using the transmission processing feedback type FIR filter. A receiver includes a reception processing feedback type FIR filter configured similarly to the transmission processing feedback type FIR filter and performs reception processing by using the reception processing feedback type FIR filter.Type: GrantFiled: January 14, 2019Date of Patent: April 21, 2020Assignee: RENESAS ELECTRONICS CORPORATIONInventors: Hirofumi Nakano, Yoshitaka Shibuya
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Publication number: 20190253297Abstract: To reduce a hardware circuit scale and a memory capacity in a communication system reducing a PAPR. A transmitter includes a transmission processing feedback type FIR filter configured to feed back data outputted from the last stage delay element of a plurality of delay elements included in an FIR filter to the first stage delay element and configured to set an initial value to a delay element in a predetermined position, of the delay elements, and performs transmission processing by using the transmission processing feedback type FIR filter. A receiver includes a reception processing feedback type FIR filter configured similarly to the transmission processing feedback type FIR filter and performs reception processing by using the reception processing feedback type FIR filter.Type: ApplicationFiled: January 14, 2019Publication date: August 15, 2019Inventors: Hirofumi NAKANO, Yoshitaka SHIBUYA
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Patent number: 10193126Abstract: A battery terminal includes a shaft portion and a flange portion. The battery terminal is made of a clad material in which at least a first metal layer and a second metal layer are bonded to each other. Each of the shaft portion and the flange portion includes the first metal layer on a first side in a shaft direction and the second metal layer on a second side in the shaft direction. The first metal layer in the shaft portion includes a protruding portion that further protrudes to the second side in the shaft direction with respect to a surface of the first metal layer on the second side in the shaft direction in the flange portion.Type: GrantFiled: October 23, 2015Date of Patent: January 29, 2019Assignees: HITACHI METALS, LTD., AOYAMA SEISAKUSHO IBARAKI PLANT CO., LTD.Inventors: Yoshimitsu Oda, Masaharu Yamamoto, Masaaki Ishio, Naonori Ishii, Hirofumi Nakano
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Publication number: 20180292396Abstract: Provided is a method for measuring tyrosine phosphatase and tyrosine kinase activity, as a high-sensitivity measuring method, which is suitable for high throughput and which uses a compound represented by general formula (I) (in the formula, A represents a conjugated ring; L represents a linker or the like having a labeling substance at an end; R1 represents a hydrogen atom or the like; and R2 and R3 each represent a hydrogen atom, an alkyl group or the like).Type: ApplicationFiled: September 26, 2016Publication date: October 11, 2018Applicant: TOKYO INSTITUTE OF TECHNOLOGYInventors: Shinichi SATO, Hiroyuki NAKAMURA, Hirofumi NAKANO
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Publication number: 20170145005Abstract: [Problem] To provide a novel PIM-3 inhibitor and a novel cancer therapeutic drug, in particular, a therapeutic drug for pancreatic cancer. [Solution] A PIM-3 kinase inhibitor comprising a compound represented by general formula (I) or a pharmacologically acceptable salt, hydrate or solvate thereof.Type: ApplicationFiled: February 13, 2015Publication date: May 25, 2017Applicant: THE UNIVERSITY OF TOKYOInventors: Tetsuo NAGANO, Hirofumi NAKANO, Tsukasa HASEGAWA, Nae SAITO, Hirotatsu KOJIMA, Takayoshi OKABE, Naofumi MUKAIDA
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Publication number: 20160368895Abstract: [Problem] The present invention addresses the problem of providing a compound that is useful for preventing or treating diseases associated with malfunctioning of PGI2 receptors, in particular, pulmonary hypertension. [Solution] A positive allosteric regulator of a PGI2 receptor which comprises a compound represented by formula (1) or a pharmaceutically acceptable salt, hydrate or solvate thereof. (1) (In the formula, R1 is a branched chain or cyclic alkyl or alkenyl having 3 to 10 carbon atoms which may be substituted, R2 is a hydrogen atom or an alkyl having 1 to 6 carbon atoms which may be substituted, R3 is 1 to 4 substituents which are the same or different independently selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl having 1 to 6 carbon atoms which may be substituted, and an alkoxy having 1 to 6 carbon atoms which may be substituted, and A is an aryl which may be substituted or a heteroaryl which may be substituted.Type: ApplicationFiled: November 27, 2014Publication date: December 22, 2016Applicants: THE UNIVERSITY OF TOKYO, NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITYInventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Toshifumi SUZUKI, Kenjiro HANAOKA, Manabu SHIMONISHI, Shinichiro EGASHIRA, Hirofumi NAKANO, Kazuo KUMAGAI, Hiroyuki MIYACHI, Kenji MATSUNO, Minoru WAKI
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Patent number: 9453278Abstract: A deposition device that deposits material particles includes an ionization section that ionizes the material particles utilizing a photoelectric effect in a reaction chamber to which the material particles are supplied, and an electrode section that guides the ionized material particles to a given area utilizing a Coulomb force.Type: GrantFiled: May 21, 2013Date of Patent: September 27, 2016Assignee: Labotec LimitedInventor: Hirofumi Nakano
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Patent number: 9437865Abstract: To provide an active material having high capacity and excellent cycle characteristics. An active material has a layered crystal structure and is expressed by a compositional formula (1) LiyNiaCobMncMdOx (1), where the element M is at least one kind of element selected from the group consisting of Al, Si, Zr, Ti, Fe, Mg, Nb, Ba, and V; 1.9?(a+b+c+d+y)?2.1; 1.05?y?1.35; 0<a?0.3; 0<b?0.25; 0.3?c?0.7; 0?d?0.1; and 1.9?x?2.1, and wherein 0.69?Ni?/Ni??0.85, where Ni? is the Ni composition amount at a center portion of the active material primary particle, and Ni? is the Ni composition amount in the vicinity of a surface (in a width of 30 nm from the surface).Type: GrantFiled: March 26, 2013Date of Patent: September 6, 2016Assignee: TDK CORPORATIONInventors: Hideaki Seki, Tomohiko Kato, Hirofumi Nakano, Atsushi Sano
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Publication number: 20160118641Abstract: A battery terminal includes a shaft portion and a flange portion. The battery terminal is made of a clad material in which at least a first metal layer and a second metal layer are bonded to each other. Each of the shaft portion and the flange portion includes the first metal layer on a first side in a shaft direction and the second metal layer on a second side in the shaft direction. The first metal layer in the shaft portion includes a protruding portion that further protrudes to the second side in the shaft direction with respect to a surface of the first metal layer on the second side in the shaft direction in the flange portion.Type: ApplicationFiled: October 23, 2015Publication date: April 28, 2016Applicants: NEOMAX MATERIALS CO., LTD., HITACHI METALS, LTD., AOYAMA SEISAKUSHO IBARAKI PLANT CO,. LTD.Inventors: Yoshimitsu Oda, Masaharu Yamamoto, Masaaki Ishio, Naonori Ishii, Hirofumi Nakano
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Publication number: 20150344404Abstract: The present invention to provide a novel pyruvate dehydrogenase kinase inhibitors. A pyruvate dehydrogenase kinase inhibitor comprising a compound represented by the general formula (I) as an active ingredient (wherein, ring A represents a 6-membered aromatic hydrocarbon ring optionally substituted with 2-4 substituents, R1 and R4, which are the same or different, represent a hydrogen atom, a hydroxyl group, an optionally substituted C1-6 alkyl group, R2 and R3, which are the same or different, represent a hydrogen atom, a carboxyl group, an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group, or a group represented by —C (?R9)—R10), a pharmaceutical composition for treatment or prophylaxis of diseases or disorders that pyruvate dehydrogenase kinase relates to its development or aggravation, and a cosmetic composition, and the like.Type: ApplicationFiled: December 26, 2013Publication date: December 3, 2015Inventors: Satoshi OMURA, Hirofumi NAKANO, Kenzaburo YAMAJI, Tsuyoshi YAMAMOTO, Hiroshi KIDO, Kazuhiko YAMANE, Toshiaki SUNAZUKA, Tomoyasu HIROSE
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Publication number: 20150335610Abstract: The purpose of the present invention is to provide a therapeutic agent or preventive agent for exacerbation of influenza, specifically to provide a novel pyruvate dehydrogenase kinase 4 (PDK4) inhibitor. The present invention relates to a PDK4 inhibitor, medical composition or cosmetic composition containing as the active ingredient a compound represented by any one of the following general formulas (I) through (III) and a pharmaceutically acceptable ester derivative thereof, or a pharmaceutically acceptable salt of the same.Type: ApplicationFiled: October 17, 2013Publication date: November 26, 2015Applicants: THE UNIVERSITY OF TOKUSHIMA, THE KITASATO INSTITUTEInventors: Satoshi OMURA, Hirofumi NAKANO, Kenzaburo YAMAJI, Tsuyoshi YAMAMOTO, Hiroshi KIDO, Junji CHIDA, Kazuhiko YAMANE
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Patent number: 9156827Abstract: An anticancer agent comprising a compound represented by the formula (I) [R1 represents hydrogen atom, hydroxyl group, a C1-6 alkoxy group and the like; R2 and R3 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; R4 represents hydrogen atom, a C1-6 alkyl group, a C1-6 alkylsulfonyl group and the like; R5 represents hydrogen atom or a substituent; represents a single bond or a double bond; R6 and R7 represents hydrogen atom, a C1-6 alkyl group and the like; R8 represents hydrogen atom, a C1-6 alkyl group and the like; A represents —O—, —S—, or —CH2—; D represents —C? or —N?; X represents methylene group, —O—, or —CO—; Q represents —N? or —C(R8)?; and Y represents a heterocyclic group or amino group], which shows a superior inhibitory activity against pim-1 kinase.Type: GrantFiled: April 28, 2011Date of Patent: October 13, 2015Assignees: THE UNIVERSITY OF TOKYO, RIKENInventors: Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Nae Saito, Hirofumi Nakano, Masanao Abe, Akiko Tanaka, Teruki Honma, Shigeyuki Yokoyama, Keiko Tsuganezawa, Hitomi Yuki
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Patent number: 9111649Abstract: There is provided a semiconductor device which is simple in configuration and resistant to tampering. A user input unit receives an authentication code input by a user. A CPU determines whether a user's access is legal based on the input authentication code and activates an enable signal if the user's access is legal. A normal row decoder decodes the row address specified by the CPU and selects a normal memory cell of any row based on the result of decode. A redundancy row decoder prohibits the selection by the normal row decoder when the specified row address agrees with the row address of a predetermined normal memory cell only if the enable signal is activated and selects a redundant memory cell of any row.Type: GrantFiled: May 11, 2011Date of Patent: August 18, 2015Assignee: RENESAS ELECTRONICS CORPORATIONInventors: Yoshifumi Kawamura, Hirofumi Nakano, Hiroyuki Kawai
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Publication number: 20150118410Abstract: A deposition device that deposits material particles includes an ionization section that ionizes the material particles utilizing a photoelectric effect in a reaction chamber to which the material particles are supplied, and an electrode section that guides the ionized material particles to a given area utilizing a Coulomb force.Type: ApplicationFiled: May 21, 2013Publication date: April 30, 2015Inventor: Hirofumi Nakano