Patents by Inventor Hiroshi Ishihara

Hiroshi Ishihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11071713
    Abstract: The present invention provides a novel liposome composition containing eribulin or its pharmacologically permissible salt, and its method of manufacture.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: July 27, 2021
    Assignee: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Hiroshi Kikuchi, Kenji Hyodo, Hiroshi Ishihara
  • Patent number: 10985839
    Abstract: In the mobile communications of the fifth generation or the like, a radio relay apparatus capable of stably over a wide area realize a three-dimensional network, in which a propagation delay is low, a simultaneous connection with a large number of terminal apparatuses in a wide-range and high-speed communication can be performed, and a system capacity per unit area is large, in radio communications with terminal apparatuses including devices for the IoT, and there is no influence on radio wave frequency resources, is provided.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: April 20, 2021
    Assignee: SoftBank Corp.
    Inventors: Shinichi Tanaka, Hiroshi Ishihara
  • Publication number: 20210083769
    Abstract: In the mobile communications of the fifth generation or the like, a radio relay apparatus capable of stably over a wide area realize a three-dimensional network, in which a propagation delay is low, a simultaneous connection with a large number of terminal apparatuses in a wide-range and high-speed communication can be performed, and a system capacity per unit area is large, in radio communications with terminal apparatuses including devices for the IoT, and there is no influence on radio wave frequency resources, is provided.
    Type: Application
    Filed: June 12, 2018
    Publication date: March 18, 2021
    Applicant: SoftBank Corp.
    Inventors: Shinichi Tanaka, Hiroshi Ishihara
  • Publication number: 20210023004
    Abstract: The present invention provides a novel liposome composition containing eribulin or its pharmacologically permissible salt, and its method of manufacture.
    Type: Application
    Filed: October 9, 2020
    Publication date: January 28, 2021
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Hiroshi KIKUCHI, Kenji HYODO, Hiroshi ISHIHARA
  • Patent number: 10765633
    Abstract: A formulation comprising liposomes, wherein the liposomes comprise, based on the liposome, 0.7 to 3.0 mol % of eritoran or a pharmaceutically acceptable salt thereof and 0.5 to 3.0 mol % of a PEGylated phospholipid.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: September 8, 2020
    Assignee: EISAI R&D MANAGEMENT CO., LTD
    Inventors: Hiroshi Ishihara, Katsura Hata, Hiroki Muto, Geoff Hird
  • Publication number: 20200188300
    Abstract: A formulation comprising liposomes, wherein the liposomes comprise, based on the liposome, 0.7 to 3.0 mol % of eritoran or a pharmaceutically acceptable salt thereof and 0.5 to 3.0 mol % of a PEGylated phospholipid.
    Type: Application
    Filed: December 13, 2019
    Publication date: June 18, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Hiroshi Ishihara, Katsura Hata, Hiroki Muto, Geoff Hird
  • Patent number: 9968583
    Abstract: The present invention provides a method of manufacture of a liposome composition including a step in which: a liposome dispersion liquid containing a liposome, and further containing cyclodextrin in the liposome internal phase is provided and a step in which an active compound is introduced into said liposome internal phase, and the liposome composition.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: May 15, 2018
    Assignee: EISAI R & D MANAGEMENT CO., LTD.
    Inventors: Hiroshi Kikuchi, Kenji Hyodo, Hiroshi Ishihara
  • Patent number: 8849702
    Abstract: An information processing apparatus includes a receiving unit configured to receive a utilization request for one of plural services provided by a computer; a service attribute information storage unit configured to store service attribute information of each of the services, the service attribute information including information indicating a type of the service and information indicating an evaluation of a content of the service; and a service recommending unit configured to search the service attribute information storage unit for the service attribute information corresponding to the type of the requested service, and determine a utilization-recommended service based on the evaluation information in the service attribute information retrieved from the service attribute information storage unit.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: September 30, 2014
    Assignee: Ricoh Company, Ltd.
    Inventors: Hiroshi Ishihara, Keiichi Suzuki, Michihiko Tsuda
  • Publication number: 20140044777
    Abstract: The present invention provides a novel liposome composition containing eribulin or its pharmacologically permissible salt, and its method of manufacture.
    Type: Application
    Filed: October 23, 2013
    Publication date: February 13, 2014
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Hiroshi KIKUCHI, Kenji HYODO, Hiroshi ISHIHARA
  • Patent number: 8297715
    Abstract: A braking system includes first pressure sensors 35, 35 which are provided to braking pipes 41, 41 which constitute first input-side pressure sensors for detecting a liquid pressure on a front-wheel-master-cylinder-25 side and a rear-wheel-master-cylinder-82 side, and second pressure sensors 36, 36 which are provided at positions closer to a stroke-simulator-28 side than second solenoid-operated valves 31, 31 of braking pipes 27,27 which constitute second input-side pressure sensors for detecting a liquid pressure on the stroke-simulator-28 side.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: October 30, 2012
    Assignee: Honda Motor Co., Ltd.
    Inventors: Yutaka Nishikawa, Kazuya Takenouchi, Takehiko Nanri, Masaie Kato, Yoko Uno, Shinji Takayanagi, Hiroshi Ishihara
  • Publication number: 20120128757
    Abstract: The present invention provides a method of manufacture of a liposome composition including a step in which: a liposome dispersion liquid containing a liposome, and further containing cyclodextrin in the liposome internal phase is provided and a step in which an active compound is introduced into said liposome internal phase, and the liposome composition.
    Type: Application
    Filed: March 30, 2010
    Publication date: May 24, 2012
    Applicant: EISAI R&D MANAGEMENT CO., LTD
    Inventors: Hiroshi Kikuchi, Kenji Hyodo, Hiroshi Ishihara
  • Publication number: 20120058178
    Abstract: The present invention provides a novel liposome composition containing eribulin or its pharmacologically permissible salt, and its method of manufacture.
    Type: Application
    Filed: March 30, 2010
    Publication date: March 8, 2012
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Hiroshi Kikuchi, Kenji Hyodo, Hiroshi Ishihara
  • Publication number: 20110295695
    Abstract: An information processing apparatus includes a receiving unit configured to receive a utilization request for one of plural services provided by a computer; a service attribute information storage unit configured to store service attribute information of each of the services, the service attribute information including information indicating a type of the service and information indicating an evaluation of a content of the service; and a service recommending unit configured to search the service attribute information storage unit for the service attribute information corresponding to the type of the requested service, and determine a utilization-recommended service based on the evaluation information in the service attribute information retrieved from the service attribute information storage unit.
    Type: Application
    Filed: January 25, 2010
    Publication date: December 1, 2011
    Inventors: Hiroshi Ishihara, Keiichi Suzuki, Michihiko Tsuda
  • Publication number: 20110061418
    Abstract: A heat pump type hot-water heater includes a hot-water tank, a heat pump cycle for heating hot water, a partition plate which divides an interior of the hot-water tank into an upper space and a lower space, a hot-water supply heat exchanger which exchanges heat of water with heat of hot water in the hot-water tank to produce high temperature hot water, a hot water supply pump which sends hot water in the hot-water tank to the hot-water supply heat exchanger, a heating terminal which heats a room, and a heating pump which sends hot water in the hot-water tank to the heating terminal.
    Type: Application
    Filed: February 12, 2010
    Publication date: March 17, 2011
    Applicant: Panasonic Corporation
    Inventors: Hiroshi Ishihara, Toshihiro Horiuchi, Toshikatsu Fukunaga, Yoshitaka Suita
  • Patent number: 7895748
    Abstract: Disclosed is a method of molding a resin coated bearing. When a molten resin is injected toward a substantially central portion of a disk space of forming dies from a sprue formed on an upper die, the molten resin is filled into a cavity through a film gate after the molten resin is led to the disk space from a pin gate, so that any weld is absent on a resin member, which covers an outer race, thus enabling uniformizing a coating member in resin strength and suppressing generation of crack on the coating member even at the time of high loading. Also, since the film gate formed on a whole peripheral edge of the disk space is formed from a lower die and an upper die, there is an advantage that after working suffices to take out a resin coated bearing from the both dies and to cut a runner in the disk space.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: March 1, 2011
    Assignees: Daido Metal Company Ltd., Sunhill Inc.
    Inventors: Takumi Nomura, Hiroshi Naito, Yoshichika Ito, Hiroshi Ishihara, Shuichi Matsumoto, Terumitsu Tanio
  • Patent number: 7790887
    Abstract: The present invention provides the compound of formula (I) in a solid form which, as a bulk medicament for pharmaceutical manufacture, is uniform, has a high purity, and is easy to work with. The invention further provides a process for preparing this compound, and pharmaceutical compositions containing the same. A solid form of (8E,12E,14E)-7-{(4-cycloheptylpiperazin-1-yl)carbonyl}oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide which has uniform specifications and is easy to work with was developed.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: September 7, 2010
    Assignees: Eisai R&D Management Co., Ltd., Mercian Corporation
    Inventors: Hiroshi Ishihara, Manabu Sasho, Keizo Sato, Takashi Kamahara, Masashi Yoshida
  • Patent number: 7767812
    Abstract: Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one having a diffraction peak at a diffraction angle (2?±0.2°) of 9.7° and/or 21.9° in a powder X-ray diffraction are suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation. Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate and amorphous 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate are also suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: August 3, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Hitoshi Harada, Hiroshi Ishihara, Yoshiaki Sato, Hiroyuki Chiba, Yuki Komatsu, Susumu Inoue, Naoki Ozeki
  • Publication number: 20100179321
    Abstract: The present invention provides a salt of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one and a crystal thereof.
    Type: Application
    Filed: September 6, 2007
    Publication date: July 15, 2010
    Inventors: Hiroshi Ishihara, Yoshiaki Sato
  • Patent number: 7727843
    Abstract: The invention relates to a semiconductor element used for a nonvolatile semiconductor storage device or the like, a semiconductor storage device using the same, a data writing method thereof, a data reading method thereof and a manufacturing method of those, and has an object to provide a semiconductor element in which scaling and integration of cells are possible, storage characteristics of data are excellent, and reduction in power consumption is possible, a semiconductor storage device using the same, a data writing method thereof, a data reading method thereof, and a manufacturing method of those.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: June 1, 2010
    Assignee: Fujitsu Microelectronics Limited
    Inventors: Hiroshi Ishihara, Kenji Maruyama, Tetsuro Tamura, Hiromasa Hoko
  • Patent number: 7718807
    Abstract: An acid addition salt of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one or a hydrate thereof, wherein the acid is selected from the group consisting of benzenesulfonic acid, p-toluenesulfonic acid, hydrochloric acid, hydrobromic acid, sulfuric acid, methanesulfonic acid, fumaric acid, tartaric acid, succinic acid and benzoic acid.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: May 18, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Satoshi Nagato, Kohshi Ueno, Hiroshi Ishihara, Yukiko Sugaya, Koichi Ito