Patents by Inventor Hiroshi Ishihara

Hiroshi Ishihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7655442
    Abstract: The present invention provides a method for stabilizing a macrolide compound, and an efficient method for producing the compound. Specifically, it provides a method for stabilizing a macrolide compound, in which a 12-membered ring macrolide compound, such as a compound expressed by the formula (1) and a cyclodextrin are both present, and a method for producing a macrolide compound, in which a cyclodextrin is made to be present in a culture broth of actinomycetes having an ability of producing the macrolide compound.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: February 2, 2010
    Assignees: Eisai R&D Management Co., Ltd., Mercian Corporation
    Inventors: Hiroshi Ishihara, Susumu Takeda, Tomonari Yamada, Yoshiaki Asahi
  • Patent number: 7607963
    Abstract: A control apparatus for opening/closing a vehicle door includes a door opening/closing mechanism for operating the vehicle door, a driving source for driving the door opening/closing mechanism, a connecting/disconnecting apparatus interposed between the door opening/closing mechanism and the driving source, and a controlling apparatus for controlling the connecting/disconnecting apparatus. The controlling apparatus for opening/closing the vehicle door includes a door movement-detecting apparatus for detecting a movement of the vehicle door. The controlling apparatus switches the connecting/disconnecting apparatus from a connected state to a disconnected state when the driving source is stopped during in an opening/closing operation of the vehicle door.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: October 27, 2009
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Hiroshi Ishihara, Yasuyuki Kozawa, Junichi Matsunaga
  • Publication number: 20090182149
    Abstract: Salts of 2-[({4-[(2,2-dimethyl-1,3-dioxan-5-yl)methoxy]-3,5-dimethylpyridin-2-yl}methyl)sulfinyl]-1H-benzimidazole and their crystalline and amorphous forms.
    Type: Application
    Filed: October 13, 2006
    Publication date: July 16, 2009
    Inventors: Tetsuya Kawahara, Hitoshi Harada, Hiroki Terauchi, Nobuhisa Watanabe, Masato Ueda, Atsushi Kamada, Sachiko Kikuchi, Hiroshi Ishihara, Koichi Koyama
  • Publication number: 20090111986
    Abstract: Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one having a diffraction peak at a diffraction angle (2?±0.2°) of 9.7° and/or 21.9° in a powder X-ray diffraction are suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation. Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate and amorphous 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate are also suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation.
    Type: Application
    Filed: December 30, 2008
    Publication date: April 30, 2009
    Inventors: Hitoshi HARADA, Hiroshi Ishihara, Yoshiaki Sato, Hiroyuki Chiba, Yuki Komatsu, Susumu Inoue, Naoki Ozeki
  • Publication number: 20090096283
    Abstract: A braking system includes first pressure sensors 35, 35 which are provided to braking pipes 41, 41 which constitute first input-side pressure sensors for detecting a liquid pressure on a front-wheel-master-cylinder-25 side and a rear-wheel-master-cylinder-82 side, and second pressure sensors 36, 36 which are provided at positions closer to a stroke-simulator-28 side than second solenoid-operated valves 31, 31 of braking pipes 27,27 which constitute second input-side pressure sensors for detecting a liquid pressure on the stroke-simulator-28 side.
    Type: Application
    Filed: September 23, 2008
    Publication date: April 16, 2009
    Inventors: Yutaka NISHIKAWA, Kazuya TAKENOUCHI, Takehiko NANRI, Masaie KATO, Yoko UNO, Shinji TAKAYANAGI, Hiroshi ISHIHARA
  • Publication number: 20090054654
    Abstract: An acid addition salt of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one or a hydrate thereof, wherein the acid is selected from the group consisting of benzenesulfonic acid, p-toluenesulfonic acid, hydrochloric acid, hydrobromic acid, sulfuric acid, methanesulfonic acid, fumaric acid, tartaric acid, succinic acid and benzoic acid.
    Type: Application
    Filed: April 27, 2007
    Publication date: February 26, 2009
    Inventors: Satoshi Nagato, Kohshi Ueno, Hiroshi Ishihara, Yukiko Sugaya, Koichi Ito
  • Patent number: 7465980
    Abstract: A ferroelectric memory device includes a gate electrode formed on a semiconductor body via a ferroelectric film, first and second diffusion regions being formed in the semiconductor body at respective sides of a channel region, wherein the ferroelectric film comprises a first region located in the vicinity of the first diffusion region, a second region located in the vicinity of the second diffusion region, and a third region located between the first and second regions, wherein the first, second and third regions carry respective, mutually independent polarizations.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: December 16, 2008
    Assignees: Fujitsu Limited, Tokyo Institute of Technology
    Inventors: Yoshihiro Arimoto, Hiroshi Ishihara, Tetsuro Tamura, Hiromasa Hoko, Koji Aizawa, Yoshiaki Tabuchi, Masaomi Yamaguchi, Yasuo Nara, Kazuhiro Takahashi, Satoshi Hasegawa
  • Publication number: 20080214564
    Abstract: The present invention provides the compound of formula (I) in a solid form which, as a bulk medicament for pharmaceutical manufacture, is uniform, has a high purity, and is easy to work with. The invention further provides a process for preparing this compound, and pharmaceutical compositions containing the same. A solid form of (8E,12E,14E)-7-{(4-cycloheptylpiperazin-1-yl)carbonyl}oxy-3,6,16,21-tetrahydroxy-6,10,12,16,20-pentamethyl-18,19-epoxytricosa-8,12,14-trien-11-olide which has uniform specifications and is easy to work with was developed.
    Type: Application
    Filed: January 28, 2008
    Publication date: September 4, 2008
    Applicants: Eisai R&D Management Co., Ltd., MERCIAN CORPORATION
    Inventors: Hiroshi ISHIHARA, Manabu Sasho, Keizo Sato, Takashi Kamahara, Masashi Yoshida
  • Patent number: 7396928
    Abstract: Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one having a diffraction peak at a diffraction angle (2?±0.2°) of 12.8°, 18.1° and/or 23.5° in a powder X-ray diffraction are excellent in stability against light, therefore are suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: July 8, 2008
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Hitoshi Harada, Hiroshi Ishihara, Yoshiaki Sato, Hiroyuki Chiba, Teiji Takigawa
  • Patent number: 7369277
    Abstract: A drawing instruction processor refers to a bit map line table that shows whether the bit arrays in the row unit are the same in the order of concentrations. The drawing instruction processor decides whether dither patterns to be used for the adjacent specified drawing ranges are the same, by referring to the BLT, and links the drawing ranges to which the same pattern can be applied. Based on this, the drawing processor carries out a batch writing using a dither pattern prepared in advance into the specified range in the page memory. The dither pattern to be used for the drawing is prepared by linking a plurality of the same basic patterns to have a length corresponding to the length of the word length. As a result of such an arrangement, it is possible to achieve a high-speed processing.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: May 6, 2008
    Assignee: Ricoh Company, Ltd.
    Inventor: Hiroshi Ishihara
  • Publication number: 20080104723
    Abstract: To comprehensively modify genome, it is intended to develop a transposition system of the copy and paste type which has an improved efficiency. This object has been achieved by the finding that an LTR retrotransposon is partly usable in a transposition system. Namely, a technique of efficiently transferring a foreign gene into a cell by using a transposon. More specifically speaking, a complete IPA element and a functional promoter sequence are found out. It is clarified that, without a combination of them, a retrotransposon cannot exert its function.
    Type: Application
    Filed: November 19, 2004
    Publication date: May 1, 2008
    Applicants: Osaka Industrial Promojtion Organization c/o Mydom, National Institute of Radiological Sciences
    Inventors: Junji Takeda, Hyoji Horie, Kosuke Yusa, Hiroshi Ishihara
  • Patent number: 7341291
    Abstract: A door handle device for vehicle rotatably supported by a vehicle door includes a handle portion extended in a first radial direction relative to a rotational axis and positioned outside the vehicle door, a lever portion extended in a second radial direction relative to the rotational axis and positioned in the vehicle door, the lever portion being connected to a connection member for transmitting operational force of door lock release to a door lock mechanism, and a counterweight provided at the handle portion.
    Type: Grant
    Filed: March 16, 2005
    Date of Patent: March 11, 2008
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Kouji Ooe, Hiroshi Ishihara, Yoshikatsu Furuya, Takayuki Miyahara
  • Patent number: 7330196
    Abstract: An image processing apparatus includes an overlay detector and a memory. The image processing apparatus and method sequentially process graphic rendering instructions for image data. The graphic rendering instructions include first and second graphic rendering instructions. The first graphic rendering instruction is input immediately preceding said second graphic rendering instruction. The first graphic rendering instruction contains first rendering data representing a first original image to render a first output image. The second graphic rendering instruction contains second rendering data representing a second original image to render a second output image. The first original image is overlaid by the second original image.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: February 12, 2008
    Assignee: Ricoh Company Ltd.
    Inventor: Hiroshi Ishihara
  • Publication number: 20070228432
    Abstract: The invention relates to a semiconductor element used for a nonvolatile semiconductor storage device or the like, a semiconductor storage device using the same, a data writing method thereof, a data reading method thereof and a manufacturing method of those, and has an object to provide a semiconductor element in which scaling and integration of cells are possible, storage characteristics of data are excellent, and reduction in power consumption is possible, a semiconductor storage device using the same, a data writing method thereof, a data reading method thereof, and a manufacturing method of those.
    Type: Application
    Filed: January 9, 2007
    Publication date: October 4, 2007
    Applicant: FUJITSU LIMITED
    Inventors: Hiroshi Ishihara, Kenji Maruyama, Tetsuro Tamura, Hiromasa Hoko
  • Publication number: 20070219179
    Abstract: The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. This compound has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor, and is useful as an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage.
    Type: Application
    Filed: May 11, 2005
    Publication date: September 20, 2007
    Inventors: Yuichi Suzuki, Koichi Ito, Atsushi Sasaki, Koshi Ueno, Miyuki Sakai, Hiroshi Ishihara, Atsuhiko Kubota
  • Publication number: 20070155696
    Abstract: The present invention provides a method for stabilizing a macrolide compound, and an efficient method for producing the compound. Specifically, it provides a method for stabilizing a macrolide compound, in which a 12-membered ring macrolide compound, such as a compound expressed by the formula (1) and a cyclodextrin are both present, and a method for producing a macrolide compound, in which a cyclodextrin is made to be present in a culture broth of actinomycetes having an ability of producing the macrolide compound.
    Type: Application
    Filed: January 28, 2005
    Publication date: July 5, 2007
    Inventors: Hiroshi Ishihara, Susumu Takeda, Tomonari Yamada, Yoshiaki Asahi
  • Publication number: 20070126246
    Abstract: A vehicle door opening/closing device includes a door handle provided at the exterior of a vehicle door and by which the vehicle door is opened and closed, control device executing a vehicle door opening process for the vehicle door on the basis of a user's door handle operation to open the vehicle door, input device provided at the door handle and inputting the user's door handle operation to open the vehicle door, wherein on the basis of the user's door handle operation to open the vehicle door, the control device executes the vehicle door opening process for one of vehicle doors, to which the door handle is not provided.
    Type: Application
    Filed: November 16, 2006
    Publication date: June 7, 2007
    Applicant: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Shintaro Suzuki, Hiroshi Ishihara
  • Publication number: 20070085239
    Abstract: Disclosed is a method of molding a resin coated bearing. When a molten resin is injected toward a substantially central portion of a disk space of forming dies from a sprue formed on an upper die, the molten resin is filled into a cavity through a film gate after the molten resin is led to the disk space from a pin gate, so that any weld is absent on a resin member, which covers an outer race, thus enabling uniformizing a coating member in resin strength and suppressing generation of crack on the coating member even at the time of high loading. Also, since the film gate formed on a whole peripheral edge of the disk space is formed from a lower die and an upper die, there is an advantage that after working suffices to take out a resin coated bearing from the both dies and to cut a runner in the disk space.
    Type: Application
    Filed: October 13, 2006
    Publication date: April 19, 2007
    Applicants: Daido Metal Company Ltd., Sunhill Inc.
    Inventors: Takumi Nomura, Hiroshi Naito, Yoshichika Ito, Hiroshi Ishihara, Shuichi Matsumoto, Terumitsu Tanio
  • Publication number: 20070078151
    Abstract: Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one having a diffraction peak at a diffraction angle (2?±0.2°) of 9.7° and/or 21.9° in a powder X-ray diffraction are suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation. Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate and amorphous 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate are also suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation.
    Type: Application
    Filed: March 20, 2006
    Publication date: April 5, 2007
    Applicant: Eisai Co., Ltd.
    Inventors: Hitoshi Harada, Hiroshi Ishihara, Yoshiaki Sato, Hiroyuki Chiba, Yuki Komatsu, Susumu Inoue, Naoki Ozeki
  • Publication number: 20060283089
    Abstract: A control apparatus for opening/closing a vehicle door includes a door opening/closing mechanism for operating the vehicle door, a driving source for driving the door opening/closing mechanism, a connecting/disconnecting apparatus interposed between the door opening/closing mechanism and the driving source, and a controlling apparatus for controlling the connecting/disconnecting apparatus. The controlling apparatus for opening/closing the vehicle door includes a door movement-detecting apparatus for detecting a movement of the vehicle door. The controlling apparatus switches the connecting/disconnecting apparatus from a connected state to a disconnected state when the driving source is stopped during in an opening/closing operation of the vehicle door.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Applicant: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Hiroshi Ishihara, Yasuyuki Kozawa, Junichi Matsunaga