Abstract: The invention provides a method of ameliorating a blood-brain barrier disorder, as well as a method of treating a disease accompanied by a blood-brain barrier disorder and a method of treating a cerebral ischemic disease, by administering a prothymosin ?, or a protein or polypeptide possessing the same function as the prothymosin ?. The invention also provides polypeptides useful in the context of the aforesaid methods.

Abstract: The solar cell module comprises: a string including solar cell elements, each including a first main surface being rectangular in shape and an electrode extending along a longitudinal direction on the first main surface, and an interconnection connecting the solar cell elements adjacent to each other along the longitudinal direction; a light-transmitting member located to cover the string; and a sealing material located between the string and the light-transmitting member. Each of solar cell elements includes a silicon substrate with the first and second main surface, and a first and second side surfaces each connecting the first and second main surface, the second side surface being located on the back side of the first side surface. The first and second side surfaces are arranged along the longitudinal direction, where silicon is exposed on the first side surface and the second side surface is covered with an insulating layer.

Abstract: A digital camera of the present invention includes a receiving portion 155 that receives a control signal from a remote controller, and a microcomputer 110 having a live view mode controlling so that image data generated by a CMOS sensor 130 or image data obtained by subjecting the image data generated by the CMOS sensor 130 to predetermined processing is displayed on a liquid crystal monitor 150 as a moving image in real time, wherein when the receiving portion 155 receives the control signal from the remote controller, the microcomputer 110 controls so as to shift the digital camera to a live view mode. Due to this configuration, in a digital camera that includes a movable mirror and is capable of displaying a subject image in a live view through an electronic viewfinder, the operability thereof can be enhanced.

Abstract: A PTFE-based sliding material, wherein the porous sintered layer on the surface of backing metal is impregnated with baked PTFE, with one or both of the solid lubricant and wear-resistant additive together with fibrous PTFE forming an entangled fibrous PTFE structure, is used for a bearing of air-conditioner. Resistance of the bearing for local wear is required. Such wear resistance is to be enhanced. Carbides of an oligomer or polymer containing a hydrophilic group formed during baking are incorporated in the entangled structure of fibrous PTFE.

Abstract: A semiconductor substrate comprises a semiconductor region of one conductivity type and a layer of another conductivity type with first, second and side surfaces. Over surfaces on the first surface side, the side surface side and an outer peripheral portion on the second surface side of the semiconductor region, the layer is formed. An electrode of the one conductivity type is located on the second surface adjacent to the layer. The semiconductor substrate includes a trench located between the outer periphery of the second surface and an end of the electrode with a spacing from the electrode and configured to isolate the layer along the outer periphery of the second surface. When viewed from the second surface side, a shortest distance between the end of the electrode and the trench is smaller than a shortest distance between a junction of the layer of the side surface side and the trench.

Abstract: According to one embodiment, an electronic device includes a receiver, a transmitter, a management module, and an informing module. The receiver receives a purchase instruction from a user. The transmitter transmits the received purchase instruction to a server via a network. The management module manages a purchase history of the user. The informing module determines, upon receiving the purchase instruction from the user, whether the received purchase instruction satisfies a predetermined condition based on a purchase history of a predetermined period, and sends a message to the user if the purchase instruction satisfies the predetermined condition.

Abstract: An object of the present invention is to provide an immunoassay that enables the rapid and convenient quantitative measurement with high detection sensitivity of a target substance in a liquid phase without the need of immobilization and washing steps and enables the visualization of an antigen.

Abstract: The invention provides a method of treating chronic pain by administering an effective amount of a low-molecular weight compound that inhibits the enzyme activity of autotaxin to a subject in need thereof, thereby treating chronic pain in the subject. The chronic pain preferably is fibromyalgia, chronic fatigue syndrome, or hypersensitivity colitis.

Abstract: An interchangeable lens including a focus lens for collecting subject light, an imaging sensor operable to generate an image signal based on the subject light, a shutter device that is arranged between the interchangeable lens and the imaging sensor and includes a first curtain and a second curtain, a pulse counter operable to detect positions of the first curtain and the second curtain, and a body controller operable to start capturing of a signal from the imaging sensor based on the positions of the first curtain and the second curtain detected by the pulse counter are provided.

Abstract: Provided is a therapeutic or prophylactic agent for generalized pain syndrome, for which no cause and therapies have been established. A therapeutic or prophylactic agent for generalized pain syndrome containing an LPA1 antagonist or autotaxin-inhibiting substance as an active ingredient. The pharmaceutical is preferably administered to the central nervous system. The generalized pain syndrome is preferably fibromyalgia, chronic fatigue syndrome or hypersensitivity colitis.

Abstract: A camera body including a receiving unit that receives an operation by a user, an obtaining unit that obtains driving method information indicating a capability of controlling a focus lens from a mounted interchangeable lens, a body controller that controls the camera body and generates a control signal for controlling the interchangeable lens, and a sending unit that sends the control signal to the interchangeable lens. The body controller determines control of the interchangeable lens by referring to the driving method information to generate a control signal that instructs the interchangeable lens to perform the determined control. The receiving unit receives a selection of one driving method setting menu from a plurality of driving method setting menus, and makes a driving method setting menu, which uses a driving method other than the driving method indicated by the driving method information, unselectable.

Abstract: The present invention provides a non-human mammal deficient in the expression of prothymosin ? gene in the striatum and a screening method for a prophylactic/therapeutic drug for Huntington's disease and the like, which uses the animal.

Abstract: A camera body includes a housing, an imaging element and a body mount. The body mount is fixed to the housing, and has a portion to which an adapter can be mounted. The body mount is disposed at a position away from the light receiving face of the imaging element by the amount of a flange back. A lens back of an interchangeable lens unit is longer than the flange back. The flange back is shorter than the length obtained by subtracting the adapter length, which is the length of the adapter in the optical axis direction, from the lens back.

Abstract: A digital camera of the present invention includes a receiving portion 155 that receives a control signal from a remote controller, and a microcomputer 110 having a live view mode controlling so that image data generated by a CMOS sensor 130 or image data obtained by subjecting the image data generated by the CMOS sensor 130 to predetermined processing is displayed on a liquid crystal monitor 150 as a moving image in real time, wherein when the receiving portion 155 receives the control signal from the remote controller, the microcomputer 110 controls so as to shift the digital camera to a live view mode. Due to this configuration, in a digital camera that includes a movable mirror and is capable of displaying a subject image in a live view through an electronic viewfinder, the operability thereof can be enhanced.

Abstract: A digital camera of the present invention includes a receiving portion 155 that receives a control signal from a remote controller, and a microcomputer 110 having a live view mode controlling so that image data generated by a CMOS sensor 130 or image data obtained by subjecting the image data generated by the CMOS sensor 130 to predetermined processing is displayed on a liquid crystal monitor 150 as a moving image in real time, wherein when the receiving portion 155 receives the control signal from the remote controller, the microcomputer 110 controls so as to shift the digital camera to a live view mode. Due to this configuration, in a digital camera that includes a movable mirror and is capable of displaying a subject image in a live view through an electronic viewfinder, the operability thereof can be enhanced.

Abstract: A camera body including a receiving unit that receives an operation by a user, an obtaining unit that obtains driving method information indicating a capability of controlling a focus lens from a mounted interchangeable lens, a body controller that controls the camera body and generates a control signal for controlling the interchangeable lens, and a sending unit that sends the control signal to the interchangeable lens. The body controller determines control of the interchangeable lens by referring to the driving method information to generate a control signal that instructs the interchangeable lens to perform the determined control. The receiving unit receives a selection of one driving method setting menu from a plurality of driving method setting menus, and makes a driving method setting menu, which uses a driving method other than the driving method indicated by the driving method information, unselectable.

Abstract: A transgenic animal other than human in which neuropsychiatric disorder condition is developed by the deletion of an HB-EGF gene is obtained. The present invention relates to a transgenic animal other than human in which an HB-EGF gene is deficient and neuropsychiatric disorder condition is developed, and a production method thereof, and a method for screening a therapeutic agent for neuropsychiatric disorder. As a transgenic animal in accordance with the present invention, a transgenic animal in which an HB-EGF gene is specifically deficient in the spiny neurons (striatum, and hippocampus) can be obtained by crossbreeding a transgenic animal that contains a genotype of Gng7(+/cre), and a transgenic animal that contains a genotype of Hb-egf(flox/flox).

Abstract: The present invention identifies a compound which binds to the PAH1 domain of mSin3B that specifically binds to neural restrictive silencer factor NRSF, and uses the compound as a prophylactic and/or a therapeutic for diseases associated with abnormal expression of neural restrictive silencer factor NRSF/REST or abnormal expression of genes targeted by NRSF/REST, such as Huntington's disease, medulloblastoma and neuropathic pain. The present invention provides a pharmaceutical composition comprising a substance capable of binding to the PAH1 domain of mSin3B, e.g.

Abstract: The present invention relates to solubility improving preparation for enhancing the oral absorption of a poorly soluble drug, which is comprising (A) and (B); (A) a granulated substance which comprises (i) a poorly soluble drug having an acidic group in the molecule, (ii) an alkaline agent, (iii) a surfactant, and this granulated substance dose not substantially contain a disintegrator, (B) a disintegrator existing only in the external of the granulated substance.

Abstract: An interchangeable lens includes a drive unit that drives a focus lens back and forth along an optical axis, a storage unit that stores driving method information indicating a driving method for autofocus control which is supported by the interchangeable lens, a sending unit that sends the driving method information to the camera body, and a lens controller that controls an operation of the interchangeable lens. A camera body determines control on the interchangeable lens by referring to the driving method information obtained from the interchangeable lens to generate a control signal. The lens controller of the interchangeable lens controls the drive unit according to the driving method instructed by the control signal received from the camera body, when autofocus control is performed.