Patents by Inventor Hitesh Batra

Hitesh Batra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF PRODUCING BERAPROST
    Publication number: 20140275573
    Abstract: An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
    Type: Application
    Filed: June 3, 2014
    Publication date: September 18, 2014
    Applicant: LUNG BIOTECHNOLOGY INC.
    Inventors: Vijay Sharma, Hitesh Batra, Sudersan Tuladhar
  • Method of producing beraprost
    Patent number: 8779170
    Abstract: An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: July 15, 2014
    Assignee: Lung Biotechnology Inc.
    Inventors: Vijay Sharma, Hitesh Batra, Sudersan Tuladhar
  • Process to prepare treprostinil
    Patent number: 8748657
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: June 10, 2014
    Assignee: United Therapeutics Corporation
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN®
    Publication number: 20130289304
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Application
    Filed: July 2, 2013
    Publication date: October 31, 2013
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN®
    Publication number: 20130267734
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Application
    Filed: June 5, 2013
    Publication date: October 10, 2013
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • Process to prepare treprostinil, the active ingredient in Remodulin®
    Patent number: 8497393
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: July 30, 2013
    Assignee: United Therapeutics Corporation
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • Treprostinil production
    Patent number: 8481782
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction. Also described are methods of preparing treprostinil comprising the alkyne addition reaction described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: July 9, 2013
    Assignee: United Therapeutics Corporation
    Inventors: Hitesh Batra, Raju Penmasta, Vijay Sharma, Sudersan M. Tuladhar, David A. Walsh
  • METHOD OF PRODUCING BERAPROST
    Publication number: 20120323025
    Abstract: An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 20, 2012
    Inventors: Vijay Sharma, Hitesh Batra, Sudersan Tuladhar
  • PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN®
    Publication number: 20120283470
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Application
    Filed: July 13, 2012
    Publication date: November 8, 2012
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • Process to prepare treprostinil, the active ingredient in remodulin
    Patent number: 8242305
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Grant
    Filed: December 15, 2008
    Date of Patent: August 14, 2012
    Assignee: United Therapeutics Corporation
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • TREPROSTINIL PRODUCTION
    Publication number: 20120197041
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Application
    Filed: March 30, 2012
    Publication date: August 2, 2012
    Inventors: Hitesh BATRA, Raju PENMASTA, Vijay SHARMA, Sudersan M. TULADHAR, David A. WALSH
  • TREPROSTINIL PRODUCTION
    Publication number: 20120190888
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Application
    Filed: March 30, 2012
    Publication date: July 26, 2012
    Inventors: Hitesh Batra, Raju Penmasta, Vijay Sharma, Sudersan M. Tuladhar, David A. Walsh
  • TREPROSTINIL PRODUCTION
    Publication number: 20110319641
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction. Also described are methods of preparing treprostinil comprising the alkyne addition reaction described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 29, 2011
    Inventors: Hitesh Batra, Raju Penmasta, Vijay Sharma, Sudersan M. Tuladhar, David A. Walsh
  • PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN
    Publication number: 20090163738
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Application
    Filed: December 15, 2008
    Publication date: June 25, 2009
    Inventors: Hitesh BATRA, Sudersan M. TULADHAR, Raju PENMASTA, David A. WALSH
  • Process for stereoselective synthesis of prostacyclin derivatives
    Patent number: 6700025
    Abstract: An improved method is described for making 9-deoxy-PGF1-type compounds. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: March 2, 2004
    Assignee: United Therapeutics Corporation
    Inventors: Robert M. Moriarty, Hitesh Batra
  • Process for stereoselective synthesis of prostacyclin derivatives
    Publication number: 20020099034
    Abstract: An improved method is described for making 9-deoxy-PGF1-type compounds. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
    Type: Application
    Filed: January 5, 2001
    Publication date: July 25, 2002
    Inventors: Robert M. Moriarty, Hitesh Batra