Abstract: A window shield with a decorative layer bonded/fused with a functional layer. The functional layer comprises materials and/or constructions that can block heat, light, and/or noise from penetrating through the window shield.

Abstract: A method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described.

Abstract: A method for authenticating a user seeking access to first and second resources that have different authentication levels. The method includes receiving a primary token that is associated with a first authentication event of the user and authenticates the user to access the first resource, and receiving a first request to access the second resource. The method further includes receiving first credentials of the user. The method further includes, responsive to validating the first credentials, generating a second authentication event, associating the second authentication event with the primary token, and issuing a first secondary token that authenticates the user to access the second resource.

Abstract: The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. Also, the invention relates to the discovery of specific hT2R9 alleles and their disparate activity in functional assays with the same biter ligands. The invention further relates to the use of these T2R receptors in assays for identifying ligands that modulate the activation of these taste receptors by specific bitter ligands and related compounds. These comounds may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste. Also T2R ligands may be used as therapeutics to treat and modulate T2R associated gastrointestinal and metabolic functions as well as treat gastrointestinal and metabolic diseases such as eating disorders, food sensing, fod absorption, obesity, diabetes, Crohn's disease, celiac disease, et al.

Abstract: In this application are described chimeric, humanized, affinity matured, stability enhanced, and bispecific Anti-GD2 antibodies and fragments thereof. Also provided are methods of using individual antibodies or compositions thereof for the detection, prevention, and/or therapeutical treatment of GD2-related diseases, in particular, neuroblastoma.

Abstract: A multi-purpose reagent composition is used for simultaneously determining concentrations of at least two analytes in a water sample. The two analytes are selected from the group consisting of free chlorine, pH, anionic polymer, and phosphates. In one embodiment, the multi-purpose reagent composition is for simultaneously determining the concentration of free chlorine and pH and comprises a free chlorine sensitive dye and pH indicator. In another embodiment, the reagent composition is for simultaneously determining of free chlorine and anionic polymer and includes a free chlorine sensitive dye, a pH buffer, cationic dye, and organic co- solvent. Thus, the pairs of free chlorine and pH or free chlorine and anionic polymer are determined using a single reagent composition. The reagent composition can also be the main reagent for one analyte analysis when it is used alone and also function as an ancillary reagent when it is combined with a second reagent composition for the determination of another analyte.

Abstract: The present invention is directed to resins made from cashew nutshell liquid and vinyl hydrocarbons and processes for manufacturing the resins. These resins exhibit lower viscosity than the phenol-based homologs. They also exhibit good compatibility with a wide range of solvents, mineral and natural oils, epoxy curing agents, liquid epoxy resins, and polymers, which make them suitable additives as non-reactive diluents for solvent-free coating formulations; tackifiers for structural adhesive, pressure sensitive and hot-melt adhesives; stabilizers for lubricants, fuel and polymer formulations; plasticizers for thermoplastic polymers and processing aid for rubber compounding and stabilizers for respective rubber artifacts. These resins are also valuable precursors for the manufacture of epoxy resins and polyols for coating, adhesive and composite omulations exhibiting ameliorated performance in water repellency, anti-corrosion, and fast hardness development during cure.

Abstract: An electronic paper apparatus including a communication module and a control module is provided. The communication module receives an electrical signal and generates a power voltage according to the electric signal. The communication module wakes up a controller during a first period of a work period by using the power voltage. The control module is electrically connected to the communication module, and includes the controller and an electronic paper display. The control module establishes a communication connection with the communication module during a second period of the work period. The power circuit module generates a driving voltage according to the power voltage to drive the electronic paper display to display image information according to the driving voltage during a display period. The first period and the second period are two continuous time intervals forming the work period. Furthermore, a driving method of the electronic paper apparatus is also provided.

Abstract: A method using a multi-purpose reagent composition to simultaneously determine concentrations of at least two analytes in a water sample. In one embodiment, the multi-purpose reagent composition used is for simultaneously determining free chlorine concentration and pH and comprises a free chlorine sensitive dye and a pH indicator. In another embodiment, the reagent composition used is for simultaneously determining of free chlorine and anionic polymer and includes a free chlorine sensitive dye, a pH buffer, a cationic dye, and an organic co-solvent. Thus, the pairs of free chlorine and pH or free chlorine and anionic polymer are determined using a single reagent composition. The reagent composition can also be the main reagent for one analyte analysis when it is used alone and also function as an ancillary reagent when it is combined with a second reagent composition for the determination of another analyte.

Abstract: The present invention is directed to resins made from cashew nutshell liquid and vinyl hydrocarbons and processes for manufacturing the resins. These resins exhibit lower viscosity than the phenol-based homologs. They also exhibit good compatibility with a wide range of solvents, mineral and natural oils, epoxy curing agents, liquid epoxy resins, and polymers, which make them suitable additives as non-reactive diluents for solvent-free coating formulations; tackifiers for structural adhesive, pressure sensitive and hot-melt adhesives; stabilizers for lubricants, fuel and polymer formulations; plasticizers for thermoplastic polymers and processing aid for rubber compounding and stabilizers for respective rubber artifacts. These resins are also valuable precursors for the manufacture of epoxy resins and polyols for coating, adhesive and composite formulations exhibiting ameliorated performance in water repellency, anti-corrosion, and fast hardness development during cure.

Abstract: The present invention discloses an application instance staging method and apparatus. The method comprising: obtaining a list of functional services bound to an application program; determining a buildpack corresponding to the bound functional service; and performing, by the determined buildpack, application instance staging of the application program. With the technical solution according to embodiments of the invention, an application program can be automatically extended during application instance staging, such that it can interact with the bound service.

Abstract: An application instance staging method comprises installing a runtime environment for an application program pushed to a cloud client; installing dependency of the application program; reading an environment variable of the application program to identify a functional service bound to the application program; modifying the application program based on the functional service bound to the application program; and packaging the modified application program, runtime environment, and dependency into an executable droplet.

Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 ?m thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.

Abstract: The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. Also the present invention relates to the use of hetero-oligomeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli.

Abstract: The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. Also, the invention relates to the discovery of specific hT2R9 alleles and their disparate activity in functional assays with the same biter ligands. The invention further relates to the use of these T2R receptors in assays for identifying ligands that modulate the activation of these taste receptors by specific bitter ligands and related compounds. These compounds may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste. Also T2R ligands may be used as therapeutics to treat and modulate T2R associated gastrointestinal and metabolic functions as well as treat gastrointestinal and metabolic diseases such as eating disorders, food sensing, food absorption, obesity, diabetes, Crohn's disease, celiac disease, et al.

Abstract: First and second nested virtual private networks share a common rekey service. A first key server generates first cryptographic keys and policies for use by gateways of the VPN to encrypt and decrypt data packets. The key server establishes a connection with a second key server to generate second cryptographic keys and policies independently of the first key server for use by encryption units of a second VPN that is nested with and operates independently of the first VPN. The first key server refreshes the first cryptographic keys in the first VPN gateways using a common rekey service, and cooperates with the second key server to refresh the second cryptographic keys in the second VPN encryption units using the common rekey service.

Abstract: A test substrate for detecting a LAL-reactive substance, wherein at least a portion of said test substrate has been pre-loaded with at least one LAL reagent and/or at least one LAL-reactive standard. Methods of use of the test substrate are disclosed. Methods of depositing test reagents on a test substrate are also disclosed.

Abstract: A microfluidic testing cartridge for testing LAL-reactive substances in fluid samples is provided. The cartridge may comprise at least two (2) testing modules, wherein each testing module includes at least one inlet port for receiving one of the fluid samples, and at least four (4) testing channels in fluid communication with the inlet port. Each of the testing channels may include a metering portion for metering an aliquot of the fluid sample, an analyzing portion, and a mixing portion, wherein a valve is positioned between the metering portion and the analyzing portion to selectively fluidly separate the metering portion from the analyzing portion. The cartridge is insertable into an optical reader which performs optical measurements of the fluid sample within each test ing channel during a testing process.

Abstract: The invention relates to compounds that specifically bind a T1R1/T1R3 or T1R2/T1R3 receptor or fragments or sub-units thereof. The present invention also relates to the use of hetero-oligomeric and chimeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli. Further, the invention relates to the constitutive of cell lines that stably or transiently co-express a combination of T1R1 and T1R3; or T1R2 and T1R3; under constitutive or inducible conditions. The use of these cells lines in cell-based assays to identify umami and sweet taste modulatory compounds is also provided, particularly high throughput screening assays that detect receptor activity by use of fluorometric imaging.

Abstract: A terminal platform is provided that can be stably supported by a bracket, and that avoids electrical contact between the bracket and a terminal fitting. Terminal fittings that form an L shape by wire connection portions and terminal main bodies are supported on a terminal platform. A platform main body of the terminal platform has (i) support-receiving portions that are supported by a support portion formed on a metal bracket, (ii) a terminal fixing portion that is positioned at a side opposite to the support-receiving portions and fixes the terminal main bodies, and (iii) a surface portion that is arranged to intersect the terminal fixing portion and the support-receiving portions, and that is along the wire connection portions. Additionally, a partition wall of the terminal platform extends to the surface portion and is arranged facing a tip end of the support portion, and separates the wire connection portions.