Patents by Inventor Howard S. An

Howard S. An has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Three-dimensional (3D) printing method
    Patent number: 10434708
    Abstract: In a 3D printing method, a sinterable material is applied and heated to a temperature ranging from about 50° C. to about 400° C. A coalescent agent is selectively applied on a portion of the sinterable material, and a modifying agent is selectively applied on the portion and/or on another portion of the sinterable material. The modifying agent consists of an inorganic salt, a surfactant, a co-solvent, a humectant, a biocide, and water. The sinterable material is exposed to radiation, whereby the coalescent agent at least partially cures the portion of the sinterable material in contact with the coalescent agent, and the modifying agent i) reduces curing of the portion of the sinterable material in contact with both the coalescent agent and the modifying agent ii) prevents curing of the other portion of the sinterable material in contact with the modifying agent, or iii) both i and ii.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: October 8, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Howard S. Tom, Hou T. Ng, Lihua Zhao, Sivapackia Ganapathiappan, Krzysztof Nauka, Yan Zhao
  • DISPENSER APPARATUS AND METHOD FOR DISPENSING DENTAL X-RAY BARRIER ENVELOPES
    Publication number: 20190300271
    Abstract: A system for dispensing X-ray barrier envelopes comprises an elongated flexible substrate having a front side and a rear side, and a plurality of X-ray barrier envelopes removably disposed on the substrate and arranged along the front side of the substrate. The substrate with the X-ray barrier envelopes is configured to be wound around a spool so that the envelopes can be dispensed by sequentially removing each envelope from the end of the spooled substrate. As the envelopes are removed from the substrate, the substrate can be trimmed or torn off so that an envelope is always disposed at the end of the substrate.
    Type: Application
    Filed: March 28, 2019
    Publication date: October 3, 2019
    Inventors: Frederick DESANTI, Michael DESANTI, Howard S. GLAZER
  • Macrocyclic immunomodulators
    Patent number: 10392405
    Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: August 27, 2019
    Assignee: ChemoCentryx, Inc.
    Inventors: Viengkham Malathong, Jeffrey McMahon, Darren J. McMurtrie, Sreenivas Punna, Howard S. Roth, Rajinder Singh, Penglie Zhang
  • Transdermally powered electric pump in reservoir inflator for inflatable medical implants
    Patent number: 10383715
    Abstract: A wirelessly controlled inflatable medical implant system includes an external control module and an implantable module. The external control module may transmit wireless power and control signals, which are received by circuitry on a flexible printed circuit board in the implantable module. In response to the received signals, circuitry in the flexible printed circuit board may cause a motor and pump combination to transfer fluid from a reservoir in the implantable device, through tubing, and into inflatable medical implant located in the penis. The flexible printed circuit board, motor, and pump may be placed within the fluid reservoir, which provides a heat sink that prevents overheating of the implant.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: August 20, 2019
    Assignee: MHN BIOTECH LLC
    Inventors: Howard S. Newman, Marcel I. Horowitz
  • Electrochromic multi-layer devices with current modulating structure
    Patent number: 10372006
    Abstract: A multi-layer device comprising a first substrate, a first electrically conductive layer on a surface thereof, and a first current modulating layer, the first electrically conductive layer having a sheet resistance to the flow of electrical current through the first electrically conductive layer that varies as a function of position.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: August 6, 2019
    Assignee: KINESTRAL TECHNOLOGIES, INC.
    Inventors: Howard S. Bergh, Jonathan Ziebarth, Nicolas Timmerman
  • LASER CUTTING STRENGTHENED GLASS
    Publication number: 20190219882
    Abstract: Methods for cutting strengthened glass are disclosed. The methods can include using a laser. The strengthened glass can include chemically strengthened, heat strengthened, and heat tempered glass. Strengthened glass with edges showing indicia of a laser cutting process are also disclosed. The strengthened glass can include an electrochromic film.
    Type: Application
    Filed: March 25, 2019
    Publication date: July 18, 2019
    Inventors: Howard S. Bergh, Nicolas Timmerman
  • High-Efficiency Transdermal Patches
    Publication number: 20190209486
    Abstract: In one embodiment, a drug is administered to a subject using a transdermal patch that includes a substrate and a layer of pressure-sensitive adhesive provided on the substrate, the pressure-sensitive adhesive comprising a blend of an adhesive compound and a carrier-drug compound, the carrier-drug compound comprising a drug transport compound and a drug that is to be delivered to the skin of the subject, wherein the drug transport compound transports the drug through the pressure-sensitive adhesive to the skin.
    Type: Application
    Filed: March 15, 2019
    Publication date: July 11, 2019
    Inventors: Howard S. Rosing, Yadong Wang
  • Eye alignment monitor and method
    Patent number: 10314482
    Abstract: An eye alignment monitor and method are described for the detection of variability of the relative alignment of the two eyes with each other, thereby detecting deficits of binocular function, for use as a screening device for these abnormalities especially in infants and young children. Each embodiment includes means for tracking of the positions of a subject's two eyes simultaneously, and furthermore includes repetitive calculation of the relative positions of the two eyes with respect to each other. The embodiments do not require fixation by either eye on a specific point. Typically, a movie on a video display is used for viewing by the subject. Variability of relative alignment of the two eyes with each other is typically determined by variability of the relative positions of images of the pupils of the eyes with respect to each other over time.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: June 11, 2019
    Assignee: The Johns Hopkins University
    Inventors: David L. Guyton, Kristina Irsch, Howard S. Ying, Boris I. Gramatikov, Robert Geary, Jing Tian, Kurt Simons
  • METAL-CONNECTED PARTICLE ARTICLES
    Publication number: 20190160534
    Abstract: Apparatus and methods for making metal-connected particle articles. A metal containing fluid is selectively applied to a layer of particles. The metal in the fluid is used to form metal connections between particles, The metal connections are formed at temperatures below the sintering temperature of the particles in the layer of particles.
    Type: Application
    Filed: February 1, 2019
    Publication date: May 30, 2019
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Kristopher J. Erickson, Krzysztof Nauka, Thomas Anthony, Lihua Zhao, Howard S. Tom
  • METAL-CONNECTED PARTICLE ARTICLES
    Publication number: 20190160532
    Abstract: Apparatus and methods for making metal-connected particle articles. A metal containing fluid is selectively applied to a layer of particles. The metal in the fluid is used to form metal connections between particles. The metal connections are formed at temperatures below the sintering temperature of the particles in the layer of particles.
    Type: Application
    Filed: January 31, 2019
    Publication date: May 30, 2019
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Kristopher J. Erickson, Krzysztof Nauka, Thomas Anthony, Lihua Zhao, Howard S. Tom
  • METAL-CONNECTED PARTICLE ARTICLES
    Publication number: 20190160533
    Abstract: Apparatus and methods for making metal-connected particle articles. A metal containing fluid is selectively applied to a layer of particles. The metal in the fluid is used to form metal connections between particles. The metal connections are formed at temperatures below the sintering temperature of the particles in the layer of particles.
    Type: Application
    Filed: February 1, 2019
    Publication date: May 30, 2019
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Kristopher J. Erickson, Krzysztof Nauka, Thomas Anthony, Lihua Zhao, Howard S. Tom
  • GENERATING THREE-DIMENSIONAL OBJECTS
    Publication number: 20190152132
    Abstract: In one example, an apparatus for generating a three-dimensional object includes an energy source to apply energy to a layer of build material to cause a first portion of the layer to coalesce and solidify, an agent distributor to selectively deliver a cooling agent onto a second portion of the layer, and a controller to control the energy source to apply energy to the layer to cause the first portion to coalesce and solidify in a first pattern and to control the agent distributor to selectively deliver the cooling agent onto the second portion of the layer in a second pattern independent of the first pattern.
    Type: Application
    Filed: January 21, 2019
    Publication date: May 23, 2019
    Inventors: Krzysztof Nauka, Esteve Comas, Alejandro Manuel De Pena, Howard S. Tom, Hou T. Ng
  • ADDITIVE MANUFACTURING INCLUDING SELECTIVE HEATING
    Publication number: 20190152134
    Abstract: To additively manufacture a 3D object, a layer of material is deposited onto a receiving surface. Droplets are selective deposited onto first portions of the layer with at least some droplets including at least a first color agent. A gas discharge illuminant selectively induces a first amount of heating in the first portions of the layer substantially greater than a second amount of heating in second portions of the layer omitting the first color agent.
    Type: Application
    Filed: July 19, 2016
    Publication date: May 23, 2019
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Krzysztof Nauka, Howard S. Tom, Kristopher Li
  • ELECTROCHROMIC MULTI-LAYER DEVICES WITH COMPOSITE ELECTRICALLY CONDUCTIVE LAYERS
    Publication number: 20190137840
    Abstract: A multi-layer device comprising a first substrate and a first electrically conductive layer on a surface thereof, the first electrically conductive layer having a sheet resistance to the flow of electrical current through the first electrically conductive layer that varies as a function of position.
    Type: Application
    Filed: June 18, 2018
    Publication date: May 9, 2019
    Inventors: Howard S. Bergh, Jonathan Ziebarth, Nicolas Timmerman
  • IMMUNOMODULATOR COMPOUNDS
    Publication number: 20190135745
    Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein Z, L, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: July 27, 2018
    Publication date: May 9, 2019
    Inventors: Christopher LANGE, Viengkham MALATHONG, Venkat Reddy MALI, Jeffrey McMAHON, Darren J. McMURTRIE, Sreenivas PUNNA, Howard S. ROTH, Rajinder SINGH, Yu WANG, Ju YANG, Penglie ZHANG
  • Modifying design layer of integrated circuit (IC) using nested and non-nested fill objects
    Patent number: 10254642
    Abstract: Various embodiments include approaches for modifying a design layer of an integrated circuit (IC). In some cases, an approach includes: identifying at least one empty region in a design layer used to form the IC; determining whether the at least one empty region requires a fill object; placing at least one fill object in the at least one empty region and tagging the at least one fill object in response to determining the at least one empty region requires a fill object; performing a simplified optical proximity correction (OPC) on the tagged at least one fill object and a complete OPC on the design layer; and generating a modified design layer including a corrected version of the design layer and modified fill objects after the performing of the simplified OPC on the tagged at least one fill object and the complete OPC on the design layer.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: April 9, 2019
    Assignee: International Business Machines Corporation
    Inventors: Veeresh V. Deshpande, Howard S. Landis, Arun Sankar Mampazhy, Neelima Mandloi
  • PELVIC ANCHOR FOR PENILE PROSTHETIC IMPLANTS
    Publication number: 20190099272
    Abstract: Embodiments of the present disclosure include a system for anchoring implantable medical devices to bones. It includes an implantable medical device such as an inflatable penile prosthesis, a sliding edge clamp for anchoring at least partially around a bone, and a prosthesis receptacle coupled to the sliding edge clamp and extending outwardly and positioned to receive the prosthesis.
    Type: Application
    Filed: September 27, 2018
    Publication date: April 4, 2019
    Applicant: MHN BIOTECH LLC
    Inventors: Howard S. NEWMAN, Arthur L. BURNETT, Marcel I. HOROWITZ
  • PROCASPASE 3 ACTIVATION BY COMBINATION THERAPY
    Publication number: 20190099418
    Abstract: The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 4, 2019
    Applicants: The Board of Trustees of the University of Illinois, Vanquish Oncology, Inc.
    Inventors: Paul J. HERGENROTHER, Rachel C. BOTHAM, Timothy M. FAN, Mark J. GILBERT, Michael K. HANDLEY, Howard S. ROTH, Theodore M. TARASOW
  • FUSING AGENT INCLUDING A METAL BIS(DITHIOLENE) COMPLEX
    Publication number: 20190092799
    Abstract: An example of a fusing agent includes a metal bis(dithiolene) complex, a thiol surfactant, a polar aprotic solvent, and a balance of water. In an example of a method of making the fusing agent, the metal bis(dithiolene) complex is exposed to an aqueous solution including a reducing agent and a thiol surfactant to form a reduced metal bis(dithiolene) complex and to dissolve the reduced metal bis(dithiolene) complex in the aqueous solution. The aqueous solution is incorporated into a vehicle including a water soluble organic solvent and an additive selected from the group consisting of an emulsifier, a surface tension reduction agent, a wetting agent, a scale inhibitor, an anti-deceleration agent, a chelating agent, an antimicrobial agent, and a combination thereof. The fusing agent may be utilized in a three-dimensional printing method and/or incorporated into a three-dimensional printing system.
    Type: Application
    Filed: February 6, 2017
    Publication date: March 28, 2019
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Paul OLUBUMMO, Lihua ZHAO, Aja HARTMAN, Howard S. TOM, Kristopher J. ERICKSON
  • Laser cutting strengthened glass
    Patent number: 10241376
    Abstract: Methods for cutting strengthened glass are disclosed. The methods can include using a laser. The strengthened glass can include chemically strengthened, heat strengthened, and heat tempered glass. Strengthened glass with edges showing indicia of a laser cutting process are also disclosed. The strengthened glass can include an electrochromic film.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: March 26, 2019
    Assignee: Kinestral Technologies, Inc.
    Inventors: Howard S. Bergh, Nicolas Timmerman