Abstract: An surgical enclosure includes electronics including at least one visual indicator and at least a first casing component enclosing the electronics therein. The first casing component is formed from a substantially transparent material and includes a first portion and a second portion. The first portion is treated to define a first finish that reduces transparency of the first portion. The second portion defines a greater transparency relative to the first portion to enable visualization of the at least one visual indicator therethrough.

Abstract: Apparatus and methods for extraction and calculation of multi-person performance metrics in a three-dimensional space. An example apparatus includes a detector to identify a first subject in a first image captured by a first image capture device based on a first set of two-dimensional kinematic keypoints in the first image, the two-dimensional kinematic keypoints corresponding to a joint of the first subject, the first image capture device associated with a first view of the first subject, a multi-view associator to verify the first subject using the first image and a second image captured by a second image capture device, the second image capture device associated with a second view of the first subject, the second view different than the first view, and a keypoint generator to generate three-dimensional keypoints for the first subject using the first set of two-dimensional kinematic keypoints.

Abstract: The present invention is brace including a main body and a strap attached to the main body for adjusting the main body around a body part. The main body and the strap are a unitary body. The brace includes a first zone having a first specific elongation and a second zone having a second specific elongation.

Abstract: Medical devices, systems and methods for occluding a left atrial appendage of a heart. In one embodiment, a medical device system includes a pusher catheter with a medical device coupled adjacent a distal end of the pusher catheter. The medical device includes a primary hub and a secondary hub with a framework extending therebetween, the primary hub including grooves defined therein. The framework is moveable between constricted and expanded positions such that as the framework moves to the constricted position the grooves are configured to align portions of the framework as the secondary hub moves through the bore of the primary hub. In another embodiment, components of the framework may be configured to minimize resistance in the system as the medical device is delivered and moved between the constricted and expanded positions.

Abstract: A method including receiving events from different data sources for a service automatically executing in an enterprise system. A first event is enriched by providing the first event with first metadata that associates the first event with a first application used by the service. The first event is assigned to a time slice associated with the first application. A second event is enriched in a similar manner. A correlation graph of nodes and edges is built using the enriched events, with nodes representing the events and edges indicating relationships between the edges. A third event indicating a fault in the first application associated with the first node is received. The source of the error for the third event is identified using the second updated correlation graph and the time slice. The source of error is then mitigated.

Abstract: An enclosure configured to hermetically seal electronics of a surgical instrument therein includes a first casing component defining a first weld deck about a perimeter thereof, a second casing component defining a second weld deck about a perimeter thereof, and an energy director extending from the first weld deck and configured to facilitate ultrasonic welding of the first and second weld decks of the first and second casing components, respectively, with one another to establish a weld seam hermetically sealing the first and second casing components. The first weld deck lies in multiple planes.

Abstract: The present disclosure is in the field of genome engineering, particularly targeted genetic modification of a CISH gene.

Abstract: A volume interrogation system can use an accelerated beam of charged particles to interrogate objects using charged-particle attenuation and scattering tomography to screen items such as portable electronic devices, packages, baggage, industrial products, or food products for the presence of materials of interest inside. The exemplary systems and methods in this patent document can be employed in checkpoint applications to scan items. Such checkpoint applications can include border crossings, mass transit terminals (subways, buses, railways, ferries, etc.), and government and private-sector facilities.

Abstract: A dual disk spindle motor hard disk drive includes a first portion having a first spindle motor and a first disk media stack mounted thereon and housed in a first enclosure, and a second portion having a coaxial second spindle motor and a second disk media stack mounted thereon and housed in a second enclosure, where the second portion further includes both the first actuator and head sliders corresponding to the first disk stack as well as the second actuator and head sliders corresponding to the second disk stack. The first and second portions are coupled together such that the open sides of the enclosures mate, referred to herein as a clamshell configuration, and each separate spindle motor is configured to operate independently of the other. With independent control of multiple spindle motors, various control functions may be utilized to address power consumption and temperature control.

Abstract: A wearable device measures heart rate recovery of a user in a non-clinical setting. The wearable device comprises a heart rate detector configured to detect heart rate data of the user, an activity sensor configured to detect motion of the user, and a processor. The processor is configured to identify a start of an activity by the user using the motion detected by the activity sensor. Responsive to detecting the start of the activity, the processor monitors the motion detected by the activity sensor to identify an end of the activity. A regression analysis is performed on heart rate data detected by the heart rate detector during a period of time after the end of the activity, and the heart rate recovery of the user is determined using the regression analysis.

Abstract: A relaxation mask includes: a main body that defines a pair of eye cavities; and a light diffuser. The light diffuser includes a first lens that is disposed within a first one of the eye cavities. A first ledge is disposed along a top edge of the first lens and extends outwardly therefrom. A first light emitting component is supported on the first ledge and is configured to fire downward into the first lens.

Abstract: This disclosure provides isolated antibodies, for example, monoclonal antibodies, that specifically bind to the C-C Motif Chemokine Receptor 8 (CCR8) expressed on the surface of a cell and mediate depletion of the CCR8-expressing cell by anti-body-dependent cellular cytotoxicity (ADCC). The disclosure provides methods for treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of an anti-CCR8 antibody as monotherapy or in combination with an anti-cancer agent such as an immune checkpoint inhibitor, for example, an anti-PD-1 or anti-PD-L1 antibody.

Abstract: Described herein are constructs used for liver-specific expression of a transgene.

Abstract: Laminable microporous polymer webs with good dimensional stability are disclosed herein. Methods of making and using laminable microporous polymer webs with good dimensional stability are also disclosed herein.

Abstract: An assembly has a chair with at least one arm. The arm has a cavity formed therein. The cavity has a bottom and a side wall. A cup is removably received in the cavity. The cup has a bottom surface and an outer wall. The cup is rotatable within the cavity. The cup has at least one projection extending upwardly from a bottom surface of the cup. This projection is adapted to support a phone thereagainst. The cup is movable between a first position in which the projection is exposed outwardly of the chair, a second position in which the projection is stowed in the cavity and a third position in which the cup is positioned beneath the cavity.

Abstract: A volume interrogation system can use an accelerated beam of charged particles to interrogate objects using charged-particle attenuation and scattering tomography to screen items such as portable electronic devices, packages, baggage, industrial products, or food products for the presence of materials of interest inside. The exemplary systems and methods in this patent document can be employed in checkpoint applications to scan items. Such checkpoint applications can include border crossings, mass transit terminals (subways, buses, railways, ferries, etc.), and government and private-sector facilities.

Abstract: A system including a data repository storing metrics describing operational behavior of software programs executing in an enterprise system. The system also includes an application programming interface (API) gateway configured to receive the metrics. The system also includes an ingestion layer configured to ingest the metrics to form the ingested metrics. The system also includes a tumbling window processor configured to process the ingested metrics and the events into heat maps, sort the heat maps into the time slices, and populate the time slices with the ingested metrics.

Abstract: Methods and apparatus are disclosed for distracting tissue. The devices and methods may include insertion of first and second elongated members into the space between two tissue layers, with an augmenting elongated member at least partially inserted therebetween to form a distraction device between the tissues to be distracted. At least one of the first and second elongated members may be formed of a flexible core member with a plurality of rigid veneer members spaced along the length of the core member. At least one of the elongated members may include a shaping member that automatically moves from a generally linear configuration to a generally less linear configuration. A deployment catheter may include a deformable distal end to allow augmentation of the tissue distraction device during implantation. An injection aid may be provided for introducing a filler material into an interior defined by a deployed tissue distraction device.

Abstract: A golf club head includes a club body and a resting face angle adjuster. The club body includes a crown opposite a sole, a toe end opposite a heel end, a back end opposite a face, and a hosel. The sole includes a sole surface. The resting face angle adjuster includes an adjustment member having a keel surface, and a recess formed in the sole such that a portion of the sole surface at least partially bounds the recess. The adjustment member is disposed in the recess and positionable between a first adjustment position and a second adjustment position. In the first adjustment position, the keel surface is at a first distance relative to the portion of the sole surface. In the second adjustment position, the keel surface is at a second distance relative to the portion of the sole surface not equal to the first distance in the direction.

Abstract: The present disclosure relates generally to tension-activated, expanding articles that include single slit patterns. In some embodiments, these articles are used as cushioning films and/or packaging materials. The present disclosure also relates to methods of making and using these tension-activated, expanding articles.