Abstract: Provided are a method for preparing chiral nitro derivatives using organic chiral catalyst compounds and water as an eco-friendly solvent, and the like. The catalyst is an organic catalyst based on (R,R)-1,2-diphenylethylenediamine (DPEN), and can prepare nitro derivatives having enantioselectivity and diastereoselectivity in excellent yield through a hydrophobic hydration effect. In particular, the preparation method of the present disclosure can stabilize a transition state through an interfacial reaction between the catalyst and water. In addition, indole derivatives can be synthesized using the chiral nitro derivatives prepared according to the present disclosure to be usefully used for the prevention or treatment of brain-nervous system diseases including depression and muscular diseases including cachexia.

Abstract: Proposed is an all-solid-state battery including a self-standing sheet layer positioned on a negative electrode current collector. The all-solid-state battery may include the negative electrode current collector, the self-standing sheet layer positioned on the negative electrode current collector, a solid electrolyte layer positioned on the sheet layer, a positive electrode active material layer positioned on the solid electrolyte layer, and a positive electrode current collector positioned on the positive electrode active material layer. The sheet layer contains carbon nanotubes.

Abstract: A display device including: a power supply configured to supply a first power, a second power, and a third power to a first power line, a second power line, and a third power line, respectively, wherein each of the first power, the second power and the third power varies in voltage level during one frame period; and pixels connected to at least one of scan lines and data lines, and connected to a common control line, the first power line, the second power line, and the third power line, wherein the pixels simultaneously emit light when the second power is changed to a low level, and a number of times the second power is changed to the low level during the one frame period changes in response to an image refresh rate.

Abstract: Discussed is a display device for improving both transmittance and efficiency of light that is transmitted through a light-emitting unit and a transmissive unit due to a phase difference of ? at an interface between an organic layer and an optical compensation layer of the display device.

Abstract: The present invention provides a method for preventing or treating liver cancer in a subject comprising administrating at least one selected from the group consisting of an Ssu72 peptide, a polynucleotide encoding the Ssu72 peptide and an expression vector containing the polynucleotide to the subject.

Abstract: A coil component includes a body having one surface, and one end surface and the other end surface, respectively connected to the one surface and opposing each other, a support substrate embedded in the body, and a coil portion disposed on the support substrate and including first and second lead-out patterns respectively exposed from surfaces of the body. The first lead-out pattern is exposed from the one surface of the body and the one end surface of the body. The second lead-out pattern is exposed from the one surface of the body and the other end surface of the body. The body includes an anchor portion disposed in each of the first and second lead-out patterns.

Abstract: Provided are a method for preparing chiral maleimide derivatives using (R,R)-1,2-diphenylethylenediamine (DPEN)-based organic chiral catalyst compounds and water as an eco-friendly solvent, and the like. It is possible to prepare chiral maleimide derivatives having high enantioselectivity even with a small amount of catalyst in an excellent yield within a short time. In particular, the preparation method of the present disclosure can stabilize a transition state through an interfacial reaction between the catalyst and water. In addition, spironolactone derivatives are synthesized using chiral maleimide derivatives prepared according to the present disclosure to be usefully used for the treatment of edema control, heart failure, liver cirrhosis, electrolyte abnormalities, hypertension, etc.

Abstract: Provided is a duct docking device for a ventilation seat of a vehicle. The duct docking device enables air to be easily blown to a seatback and a seat cushion with a passenger in a seat using only one blower by enabling a seatback duct mounted at the seatback and a seat cushion duct mounted at the seat cushion to be hermetically docked through a connector duct, etc. at an unfolded position of the seatback in which a passenger can sit, and by enabling the seatback duct mounted at the seatback and the seat cushion duct mounted at the seat cushion to be separated from each other at a folded position of the seatback in consideration of that there is no passenger in the seat.

Abstract: An air conditioner for a vehicle including an air-conditioning case divided into a plurality of air passageways by a separation wall. A heating heat exchanger is disposed inside the air-conditioning case and exchanges heat with air to heat the interior of the vehicle. A perforated member is disposed at a downstream side of the heating heat exchanger and has a plurality of perforated holes through which the air passing the heating heat exchanger passes, and a partition wall is disposed between the heating heat exchanger and the perforated member to divide the air passageway of the air-conditioning case into a plurality of air passageways, wherein the partition wall is formed integrally with the perforated member.

Abstract: A grain-oriented electrical steel sheet according to an embodiment of the present invention includes: a groove on a line formed on one surface of an electrical steel sheet in a direction crossing a rolling direction; and a thermal shock portion on a line formed on one surface of the electrical steel sheet in the direction crossing the rolling direction, wherein a distance between the groove and the thermal shock portion is 1 mm or less.

Abstract: A grain-oriented electrical steel sheet according to an embodiment of the present invention includes: a groove on a line formed on one surface of an electrical steel sheet in a direction crossing a rolling direction; and a thermal shock portion on a line formed on one surface of the electrical steel sheet in the direction crossing the rolling direction, wherein a distance between the groove and the thermal shock portion is 1 mm or less.

Abstract: The present invention relates to a composition for antioxidation, anti-inflammation, or osteoclast differentiation inhibition and a composition for arthritis treatment, each of the compositions containing a fraction of a complex extract of Cynanchum wilfordii, Phlomis umbrosa, and Angelica gigas as an active ingredient. The compositions of the present invention can be effectively used for osteoclast differentiation inhibition, antioxidation, or anti-inflammation, and arthritis treatment.

Abstract: The present invention relates to a microstructure including a biocompatible polymer or an adhesive and to a method for manufacturing the same. The present inventors optimized the aspect ratio according to the type of each microstructure, thereby ensuring the optimal tip angle and the diameter range for skin penetration. Especially, the B-type to D-type microstructures of the present invention minimize the penetration resistance due to skin elasticity at the time of skin attachment, thereby increasing the penetration rate of the structures (60% or higher) and the absorption rate of useful ingredients into the skin. In addition, the D-type microstructure of the present invention maximizes the mechanical strength of the structure by applying a triple structure, and thus can easily penetrate the skin. When the plurality of microstructures are arranged in a hexagonal arrangement type, a uniform pressure can be transmitted to the whole microstructures on the skin.

Abstract: The present invention relates to a hyaluronic acid microstructure having excellent solubility characteristics. More specifically, the present invention relates to a biodegradable microstructure comprising crosslinked hyaluronic acid and having excellent solubility characteristics during skin penetration. When the microstructure of the present invention is penetrated into the skin, the solubility characteristics in the skin are excellent, the dissolution rate in the skin can be easily controlled according to the content ratio of the crosslinked hyaluronic acid, and, while effective ingredients provided on the microstructure can be stably delivered into the skin, the release rate of the provided effective ingredients can be easily controlled, and thus the present invention can be used as a transdermal delivery system for pharmacologically active materials or skin improvement materials.

Abstract: A grain-oriented electrical steel sheet according to an embodiment of the present invention includes: a groove on a line formed on one surface of an electrical steel sheet in a direction crossing a rolling direction; and a thermal shock portion on a line formed on one surface of the electrical steel sheet in the direction crossing the rolling direction, wherein a distance between the groove and the thermal shock portion is 1 mm or less.

Abstract: The present invention relates to a composition for antioxidation, anti-inflammation, or osteoclast differentiation inhibition and a composition for arthritis treatment, each of the compositions containing a fraction of a complex extract of Cynanchum wilfordii, Phlomis umbrosa, and Angelica gigas as an active ingredient. The compositions of the present invention can be effectively used for osteoclast differentiation inhibition, antioxidation, or anti-inflammation, and arthritis treatment.

Abstract: The present invention relates to an exhaust reduction composition containing silicon carbide particles, alumina particles, and neodymium particles. When the exhaust reduction composition according to the present invention is mixed with the cooling water of an internal combustion engine, there is an advantage of enabling the discharge of exhaust material to be reduced.

Abstract: The present invention provides microstructures using crosslinked hyaluronic acid hydrogels and the method for preparing the same. The present invention for preparing microstructures using crosslinked hyaluronic acid hydrogels allows the preparation of microstructures with a uniform shape and minimum deformation. Furthermore, the microstructures made using crosslinked hyaluronic acid hydrogels in the present invention can improve skin aging, e.g. wrinkles, replenish moisture, easily absorb body fluids due to its outstanding swelling performance, provide a longer duration in the body due to its resistance against a hyaluronic acid hydrolyzing enzyme, enabling the safe delivery of effective components in the body.

Abstract: The present invention relates to a hyaluronic acid microstructure having excellent solubility characteristics. More specifically, the present invention relates to a biodegradable microstructure comprising crosslinked hyaluronic acid and having excellent solubility characteristics during skin penetration. When the microstructure of the present invention is penetrated into the skin, the solubility characteristics in the skin are excellent, the dissolution rate in the skin can be easily controlled according to the content ratio of the crosslinked hyaluronic acid, and, while effective ingredients provided on the microstructure can be stably delivered into the skin, the release rate of the provided effective ingredients can be easily controlled, and thus the present invention can be used as a transdermal delivery system for pharmacologically active materials or skin improvement materials.

Abstract: The present invention relates to a microstructure including a biocompatible polymer or an adhesive and to a method for manufacturing the same. The present inventors optimized the aspect ratio according to the type of each microstructure, thereby ensuring the optimal tip angle and the diameter range for skin penetration. Especially, the B-type to D-type microstructures of the present invention minimize the penetration resistance due to skin elasticity at the time of skin attachment, thereby increasing the penetration rate of the structures (60% or higher) and the absorption rate of useful ingredients into the skin. In addition, the D-type microstructure of the present invention maximizes the mechanical strength of the structure by applying a triple structure, and thus can easily penetrate the skin. When the plurality of microstructures are arranged in a hexagonal arrangement type, a uniform pressure can be transmitted to the whole microstructures on the skin.