Patents by Inventor James A. Nicholas

James A. Nicholas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200010868
    Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
    Type: Application
    Filed: July 2, 2019
    Publication date: January 9, 2020
    Inventors: Da Duan, Oscar Alvizo, Jovana Nazor, Harvinder Chagger Maniar, James Nicholas Riggins, Jonathan Vroom, Santhosh Sivaramakrishnan, Hao Yang, Anna Fryszkowska, Mark Huffman, Joshua Kolev, Iman Farasat, Agustina Rodriguez-Granillo, Deeptak Verma
  • Publication number: 20190366421
    Abstract: A rivet tape joining clip (302) comprising an elongate body provided with a plurality of projections (310) which extend from one side of the elongate body, wherein the projections are provided with laterally projecting lips. The invention further relates to different apparatuses and methods used for the joining of rivet tapes.
    Type: Application
    Filed: March 29, 2018
    Publication date: December 5, 2019
    Inventors: Adam James Nicholas, Joshua Allan Jackson, Nicholas Richard Clew
  • Patent number: 10487121
    Abstract: Disclosed are D-peptide compositions and methods for inhibiting HIV entry into host cells.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: November 26, 2019
    Assignees: Navigen, Inc., University of Utah Research Foundation
    Inventors: Brett D. Welch, James Nicholas Francis, Michael S. Kay
  • Publication number: 20190345458
    Abstract: The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 14, 2019
    Inventors: Nicholas J. Agard, Oscar Alvizo, Melissa Ann Mayo, Stefanie Ng Minor, James Nicholas Riggins, Jeffrey C. Moore
  • Patent number: 10463315
    Abstract: A technique for managing alarms includes acquiring a physiological parameter value and one or more alarm settings associated with the physiological parameter value. The technique also includes determining if the one or more alarm settings are associated with an adaptive alarm manager selecting an adaptive alarm condition from a plurality of adaptive alarm conditions when the one or more alarm settings are associated with the adaptive alarm manager; determining if the physiological parameter value meets the selected adaptive alarm condition; and generating an alarm in response when the physiological parameter value meets the selected adaptive alarm condition.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: November 5, 2019
    Assignee: Covidien LP
    Inventors: James Nicholas Watson, Paul S. Addison, Graeme A. Lyon
  • Patent number: 10448851
    Abstract: A PPG system for determining a stroke volume of a patient includes a PPG sensor configured to be secured to an anatomical portion of the patient. The PPG sensor is configured to sense a physiological characteristic of the patient. The PPG system may include a monitor operatively connected to the PPG sensor. The monitor receives a PPG signal from the PPG sensor. The monitor includes a pulse trending module determining a slope transit time of an upslope of a primary peak of the PPG signal. The pulse trending module determines a stroke volume of the patient as a function of the slope transit time.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: October 22, 2019
    Assignee: Covidien LP
    Inventors: Paul Stanley Addison, James Nicholas Watson
  • Patent number: 10408563
    Abstract: In an open chamber air gun, a round is gravity fed or magnetically fed into the open chamber and falls into the magnetic flux lines of a magnet disposed at the chamber. Due to the magnet, the round is pulled securely into the chamber and then remains momentarily held in place, blocking much of the air behind it and thus increasing the air pressure driving it. When the round moves down the barrel from the breech toward the muzzle, it quickly leaves the vicinity of the magnet and the magnetic drag ceases, after which the air pressure is free to drive the round to full velocity. High rates of fire and muzzle velocities are achieved with moderate air pressure and an action with no moving parts.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: September 10, 2019
    Inventor: James Nicholas Marshall
  • Patent number: 10407668
    Abstract: The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: September 10, 2019
    Assignee: Codexis, Inc.
    Inventors: Nicholas J. Agard, Oscar Alvizo, Melissa Ann Mayo, Stefanie Ng Minor, James Nicholas Riggins, Jeffrey C. Moore
  • Patent number: 10407357
    Abstract: A product made by a substantially zero carbon emission process for making amorphous poly alpha olefins including, converting alkanes to olefin monomers ethylene, propylene, and 1-butene or combinations thereof using renewable electric power in an oxidative-coupling of methane plant including the steps of passing alkanes through an ethylene plant while adding oxygen, passing the first polymerization grade ethylene through a 2-butene plant, passing a first of the two 2-butene streams and one of the polymerization grade ethylene through a propylene plant, and passing a second of the two 2-butene streams through a 1-butene plant. The next step in the process for making amorphous poly alpha olefins includes polymerizing at least one of the polymerization grade alkenes which includes applying a temperature of 130 degrees Fahrenheit to 175 degrees Fahrenheit to at least one of the polymerization grade alkenes and scrubbing at least one boiler stack gases.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: September 10, 2019
    Inventors: James Nicholas Fowler, Deborah Lawrence, Stephen Craig McHaney
  • Patent number: 10375956
    Abstract: The present invention relates to a compound of formula (I): wherein: R8 and R9, independently of each other, are hydrogen, fluorine or C1-C3alkyl; R10 is hydrogen or methyl (preferably hydrogen); and the other substituents are as defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are thought to be suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: August 13, 2019
    Assignee: Syngenta Limited
    Inventors: Ian Henry Aspinall, Stephane Andre Marie Jeanmart, James Nicholas Scutt, John Benjamin Taylor
  • Publication number: 20190241482
    Abstract: A product made by a substantially zero carbon emission process for making amorphous poly alpha olefins including, converting alkanes to olefin monomers ethylene, propylene, and 1-butene or combinations thereof using renewable electric power in an oxidative-coupling of methane plant including the steps of passing alkanes through an ethylene plant while adding oxygen, passing the first polymerization grade ethylene through a 2-butene plant, passing a first of the two 2-butene streams and one of the polymerization grade ethylene through a propylene plant, and passing a second of the two 2-butene streams through a 1-butene plant. The next step in the process for making amorphous poly alpha olefins includes polymerizing at least one of the polymerization grade alkenes which includes applying a temperature of 130 degrees Fahrenheit to 175 degrees Fahrenheit to at least one of the polymerization grade alkenes and scrubbing at least one boiler stack gases.
    Type: Application
    Filed: April 15, 2019
    Publication date: August 8, 2019
    Inventors: JAMES NICHOLAS FOWLER, DEBORAH LAWRENCE, STEPHEN CRAIG MCHANEY
  • Patent number: 10363859
    Abstract: A vehicle loadspace cover is provided that is securable to a portion of a vehicle. The loadspace cover comprises a cargo fixing point configured to secure an item of cargo to the loadspace cover.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: July 30, 2019
    Assignee: Ford Global Technologies, LLC
    Inventors: James Nicholas Murray, James Neugebauer, Bruce Southey, Richard Craven, Andrew John Murray, Ian Brazier
  • Patent number: 10293742
    Abstract: A lamp assembly for a vehicle is disclosed. The assembly includes a reflector having a proximal end and a distal end. The reflector has a surface having a plurality of reflective faces spread over an arc therebetween, the arc being generally concave. The reflector forms part of a recess, the recess having spaced-apart parallel walls. A light emitting diode (LED) light source is disposed near the proximal end of the reflector and remote from the distal end of the reflector and the light source is oriented to emit light onto the reflective faces. A lens is positioned in front of the reflector. The lens is arranged to receive light from the reflector. In use, light is output from the lens with a substantially uniform luminance over a viewing angle of at least 45 degrees in a plane.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: May 21, 2019
    Assignee: SMR Patents S.à.r.l.
    Inventors: Garry Gordon Leslie Fimeri, Simon Belcher, James Nicholas Dickson
  • Patent number: 10286816
    Abstract: A vehicle loadspace floor comprising a first deployable portion and a second deployable portion, the first and second deployable portions cooperating to form a rearward-facing seat extending through the opening of a loadspace of the vehicle when deployed from the loadspace floor.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: May 14, 2019
    Assignee: Ford Global Technologies, LLC
    Inventors: James Nicholas Murray, James Neugebauer, Richard Craven, Bruce Southey
  • Patent number: 10265005
    Abstract: According to embodiments, techniques for using continuous wavelet transforms and spectral transforms to determine oxygen saturation from photoplethysmographic (PPG) signals are disclosed. According to embodiments, a first and a second PPG signals may be received. A spectral transform of the first and the second PPG signals may be performed to produce a first and a second spectral transformed signals. A frequency region associated with a pulse rate of the PPG signals may be identified from the first and the second spectral transformed signals. According to embodiments, a continuous wavelet transform of the first and the second PPG signals may be performed at a scale corresponding to the identified frequency region to produce a first and a second wavelet transformed signals. The oxygen saturation may be determined based at least in part upon the wavelet transformed signals.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: April 23, 2019
    Assignee: NELLCOR PURITAN BENNETT IRELAND
    Inventors: James Nicholas Watson, Paul Stanley Addison
  • Patent number: 10232765
    Abstract: A lamp assembly for illuminating a ground area adjacent a vehicle is disclosed. The assembly includes a housing; an outer lens covering the housing; a plurality of light emitting diode (LED) light sources arranged in the housing; and a reflector mounted in the housing. The light emitted from the plurality of LED light sources is captured by the reflector which reflects light towards the lens, the lens directing light generally downward towards the ground area. The light output from the lamp assembly appears to be emitted from a single light source.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: March 19, 2019
    Assignee: SMR Patents S.à.r.l.
    Inventors: Garry Gordon Leslie Fimeri, Simon Belcher, James Nicholas Dickson
  • Publication number: 20190081474
    Abstract: Bus mounted surge protection devices are provided that are configured to be positioned in a panelboard alongside one or more similarly sized circuit breaker devices. The bus mounted surge protection device is configured to be received by a same provisional bus as the one or more circuit breaker devices and the bus mounted surge protection device is configured to protect all of the one or more circuit breaker devices in the panelboard.
    Type: Application
    Filed: August 28, 2018
    Publication date: March 14, 2019
    Inventors: Paul Anthony Colbaugh, Thomas Perry Colcombe, Daniel Lee Ellis, Richard Alan Orman, Daniel Joseph Resnik, Scott Anthony Seale, James Nicholas Skoczlas, David John States, Thomas Mark Young
  • Publication number: 20190023748
    Abstract: Disclosed are D-peptide compositions and methods for inhibiting HIV entry into host cells.
    Type: Application
    Filed: January 6, 2017
    Publication date: January 24, 2019
    Inventors: Brett D. WELCH, James Nicholas FRANCIS, Michael S. KAY
  • Patent number: D842257
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: March 5, 2019
    Assignee: Eaton Intelligent Power Limited
    Inventors: Paul Anthony Colbaugh, James Nicholas Skoczlas
  • Patent number: D864126
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: October 22, 2019
    Assignee: Eaton Intelligent Power Limited
    Inventors: Paul Anthony Colbaugh, James Nicholas Skoczlas