Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.

Abstract: The present invention provides engineered T7 RNA polymerase variants and compositions thereof. These variants have been evolved for selective incorporation of the symmetrical capped GTP analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for using the variants provided herein. The present invention further provides for the use of the compositions provided herein.

Abstract: A method for a vehicle is provided. The method comprises: determining a weight and position of an item of cargo being transported by the vehicle; transmitting information comprising the weight and position to a cargo management system remote from the vehicle; receiving a weight distribution instruction from the cargo management system; and communicating the weight distribution instruction to an occupant of the vehicle.

Abstract: A movable bulkhead assembly configured to partition an interior of a motor vehicle is provided. The assembly comprises a segmented shutter and a track assembly configured to guide the movement of the segmented shutter. The track assembly comprises a first vertically extending track portion, the segmented shutter being movable along the first vertically extending track portion to deploy or retract the bulkhead.

Abstract: The present invention provides engineered transglutamirase enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, methods of producing these enzymes, and methods of using the engineered transglutaminase enzymes.

Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.

Abstract: The present invention provides engineered RNA polymerase variants and compositions comprising these variants. The present invention further provides engineered T7 RNA polymerase variants and compositions comprising these variants. These variants have been evolved for selective incorporation of the m7G(5?)ppp(5?)m7G cap analog over GTP at the initiation of in vitro transcription. The present invention also provides methods for selective capping of RNA transcripts.

Abstract: A method (500) for protection of a vehicle (100), the method comprising: receiving information from a sensor (502); comparing the information with known signatures indicative of a likely attack (504); determining whether a known signature indicative of a likely attack is present (506); and if a known signature indicative of a likely attack is present, placing at least one system of the vehicle into a heightened state of alert (508).

Abstract: A method and apparatus for protecting property, wherein the method comprises receiving information indicating an attack on the property, determining, from the received information, a type of attack upon the property indicated by the received information, and transmitting a data packet to a receiver, the data packet comprising metadata describing the determined type of attack.

Abstract: A reusable modular housing system has a gridded structure comprising reusable components with dimensions corresponding to a two-unit system. The structure has floor and ceiling grids with dimensions that correspond to multiples of a first unit of measurement. The vertical beams that connect the floor and ceiling grids are spaced apart at dimensions that also correspond to multiples of the first unit of measurement. The structure has a variety of other components that can be coupled to the floor and ceiling grids and the vertical beams, and those other components have dimensions that correspond to a multiple of a second unit of measurement. Dimensions of the structure can vary, but each of the component parts can be detachably coupled into the gridded structure, so as to fit within the grid's dimensions based on respective multiples of the first unit of measurement and the second unit of measurement.

Abstract: A controller of a material handling system performs a method of creating a multidrop pattern of articles for robotic placement in layers on a pallet. A pattern is presented on a user interface of any currently positioned representations of articles on a pallet. A control affordance for inputting drag'n'drop and numeric inputs is presented on the user interface for robotic control operations to perform a multidrop of the more than one article in an end effector of a robotic arm for placement of the more than one article. User inputs are received that indicate placement position of a first subset of the more than one article. User inputs are received that indicate placement position of a second subset, which is mutually exclusive of the first subset, of the more than one article. The user inputs are converted into a place sequence of robotic control operations to perform a multidrop of the articles by the robotic arm.

Abstract: The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclopentane-1,3-dione-2-yl, a cyclohexane-1,3, 5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, or a cycloheptane-1,3-dione-2-yl, or a derivative thereof (e.g. a fused such as fused bicyclic derivative, and/or a spirocyclic derivative), or an enol ketone tautomer derivative thereof, wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is —O—R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or —CH2CH2OCH3. These compounds are suitable for use as herbicides.

Abstract: The present invention relates to a compound of formula (I) wherein: R1 is C1-C3alkoxy, C1-C2alkoxy-C1-C3alkoxy, C1-C2fluoroalkoxy, ethyl, n-propyl, n-butyl, cyclopropyl or ethynyl; R2 is hydrogen, ethyl, n-propyl, cyclopropyl, vinyl, ethynyl, C1-C3alkoxy, C1-C3fluoroalkyl, C1-C2fluoroalkoxy, C1-C2alkoxy-C1-C3alkoxy-, or C1fluoroalkoxy-C1-C3alkoxy-; provided that when R1 is ethyl, n-propyl, n-butyl, cyclopropyl or ethynyl, then R2 is hydrogen, ethyl, n-propyl, cyclopropyl, vinyl or ethynyl; and Y is O, S, S(O), S(O)2, N(C1-C2alkyl), N(C1-C2alkoxy), C(O), CR8R9 or —CR10R11CR12R13—; and G, R3, R4, R5 and R6 are as defined herein; wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are suitable for use as herbicides.

Abstract: Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides: wherein R1, R2, R3, R4, R5, R6, Q1, Q2, J, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound, N-oxide, salt or composition.

Abstract: A controller of a material handling system performs a method of creating a multidrop pattern of articles for robotic placement in layers on a pallet. A pattern is presented on a user interface of any currently positioned representations of articles on a pallet. A control affordance for inputting drag'n'drop and numeric inputs is presented on the user interface for robotic control operations to perform a multidrop of the more than one article in an end effector of a robotic arm for placement of the more than one article. User inputs are received that indicate placement position of a first subset of the more than one article. User inputs are received that indicate placement position of a second subset, which is mutually exclusive of the first subset, of the more than one article. The user inputs are converted into a place sequence of robotic control operations to perform a multidrop of the articles by the robotic arm.

Abstract: The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclohexane-1,3,5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, a cycloheptane-1,3-dione-2-yl, in which each cyclic dione is bridged by alkanediyl, or a derivative thereof (e.g. an enol ketone tautomer derivative thereof), wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is —O—R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or —CH2CH2OCH3. These compounds are suitable for use as herbicides.

Abstract: A PPG system for determining a stroke volume of a patient includes a PPG sensor configured to be secured to an anatomical portion of the patient. The PPG sensor is configured to sense a physiological characteristic of the patient. The PPG system may include a monitor operatively connected to the PPG sensor. The monitor receives a PPG signal from the PPG sensor. The monitor includes a pulse trending module determining a slope transit time of an upslope of a primary peak of the PPG signal. The pulse trending module determines a stroke volume of the patient as a function of the slope transit time.

Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.

Abstract: A rivet tape joining clip (302) comprising an elongate body provided with a plurality of projections (310) which extend from one side of the elongate body, wherein the projections are provided with laterally projecting lips. The invention further relates to different apparatuses and methods used for the joining of rivet tapes.