Abstract: An endpoint agent is enhanced with a kernel-level event tracing facility, an event manager having telemetry filters, a persistence manager, and a detection engine. The endpoint agent receives an instruction from a controller system to enable a selection of filters, including a custom-built telemetry filter for the kernel-level event tracing facility which feeds events to the event manager as they are occurring. The event manager determines which enabled telemetry filters are applicable to the events, apply them to identify events of interest, and provide those events to the detection engine which, in turn, applies detection filters to the events of interest to detect possible threats to the endpoint. The telemetry filters are evaluated in memory as the events are occurring. To increase the speed of processing, expression trees representing the telemetry filters can be compiled into machine code just in time of execution. The machine code executes extremely fast natively.

Abstract: A method by a cloud orchestrator to provide subscription-based throttling of virtual applications in a cloud. The method includes determining that a physical resource in the cloud is being overutilized, identifying a virtual application running in the cloud that utilizes the physical resource, determining that the virtual application is to be throttled based on a determination that the virtual application is subscribed to a throttling subscription registry, where the throttling subscription registry specifies a throttling mechanism by which to throttle the virtual application, and executing the throttling mechanism to throttle the virtual application in response to a determination that the virtual application is to be throttled.

Abstract: A plurality of first sensory cues are generated capable of being perceived by a user. Each first sensory cue of the plurality of first sensory cues is dependent on a position of at least one body member of a performer relative to a performance element of a performance object with which an event is performed. The plurality of first sensory cues being effective for stimulating a first processing center of a brain of the user. A plurality of visual sensory cues are generated capable of being displayed to the user on a video display device. The visual sensory cues providing a virtual visual indication to the user of the position of the at least one body member. The visual sensory cues being effective for stimulating the visual processing center of the brain of the user.

Abstract: New aluminum alloys are disclosed. The new aluminum alloys may include from 0.70 to 1.4 wt. % Si, from 0.70 to 1.3 wt. % Mg, wherein (wt. % Mg)/(wt. % Si) is not greater than 1.40, from 0.70 - 3.0 wt. % Zn, from 0.55 to 1.3 wt. % Cu, wherein the total amount of Si+Mg+Zn+Cu is not greater than 4.25 wt. %, from 0.01 to 0.30 wt. % Fe, up to 0.70 wt. % Mn, up to 0.15 wt. % Cr, up to 0.20 wt. % Zr, up to 0.20 wt. % V, and up to 0.25 wt. % Ti, the balance being aluminum, optional incidental elements and impurities. The new aluminum alloys may realize an improved combination of properties, such as an improved combination of strength, formability and/or corrosion resistance.

Abstract: A plurality of first sensory cues are generated capable of being perceived by a user. Each first sensory cue of the plurality of first sensory cues is dependent on a position of at least one body member of a performer relative to a performance element of a performance object with which an event is performed. The plurality of first sensory cues being effective for stimulating a first processing center of a brain of the user. A plurality of visual sensory cues are generated capable of being displayed to the user on a video display device. The visual sensory cues providing a virtual visual indication to the user of the position of the at least one body member. The visual sensory cues being effective for stimulating the visual processing center of the brain of the user.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: In one example, a battery includes a negative terminal, a positive terminal, an electrolyte contained between the negative terminal and the positive terminal, and a hydrogel layer positioned between and physically separating the negative terminal and the positive terminal.

Abstract: A method for energy generation includes receiving, at a carbon negative energy generation system, input including calcium oxide and water and reacting, within a reaction chamber of the carbon negative energy generation system, the calcium oxide and water to release energy and generate calcium hydroxide. The method further includes directing, by the carbon negative energy generation system, the released energy to facilitate propulsion or onboard electricity generation and dispensing, by the carbon negative energy generation system, the calcium hydroxide into the ocean to sequester atmospheric CO2.

Abstract: A side view mirror assembly includes a base frame configured to couple to a bracket that is connected to a vehicle static structure. The base frame interfacing with the bracket through a guide that is at least partially received within a pocket when the base frame is coupled to the bracket. A mirror housing assembly is adjustably supported by the base frame.

Abstract: A subterranean coring assembly can include a body having at least one wall that forms a cavity, wherein the cavity has a top end and a bottom end. The subterranean coring assembly can also include a first flow regulating device movably disposed within the cavity, where the first flow regulating device is configured to move from a first default position to a first position within the cavity based on first flow characteristics of fluid that flows into the top end of the cavity toward the bottom end of the cavity.

Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from Dengue virus that are immunogenic and elicit a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against Dengue virus subtypes following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, immunogenic compositions, vaccines, subviral particles (SVPs), and virus-like particles (VLPs) comprising Dengue virus proteins or encoding polynucleotides. Methods of generating an immune response in a subject by administering the immunogens, vaccines, SVPs, VLPs, or immunogenic compositions thereof are provided. In particular, the immunogens comprise a Dengue virus protein, or an antibody binding portion thereof.

Abstract: A system and method for monitoring one or more environmental conditions at a construction Site. Some embodiments include a system and method for sending a notification to a client device based on a trigger condition. The system may include a computer server including a web server and a database; a Coordinator and Aggregator Gateway (CAG) deployed at the construction site and In communication with the web server and a global position system (GPS) network; and one or more Wireless Sensor Nodes (WSNs) deployed at the construction site and in communication with the CAG, each of the WSNs including one or more sensors configured to measure an environmental condition of the construction site.

Abstract: Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 or LRP6 binding moiety.

Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from H3 influenza virus that are immunogenic and are capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against H3 vims following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, vaccines, virus-like particles (VLPs) and compositions comprising the immunogens and vaccines. Methods of generating an immune response in a subject by administering the immunogens, vaccines, VLPs, or compositions thereof are provided. In particular, the immunogens comprise the hemagglutinin (HA) protein of H3 influenza vims strains.

Abstract: Provided herein are methods for generating a non-naturally occurring, broadly reactive, pan-epitopic antigen derived from a pathogen, such as a virus, bacterium, and the like, that is immunogenic and is capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against the pathogen following introduction into a subject. Also provided is a non-naturally occurring immunogen generated using the methods, and vaccines and compositions comprising the immunogen. Methods of generating an immune response in a subject by administering the immunogen, vaccine, or composition are provided. In particular, the immunogen comprises the hemagglutinin (HA) or neuraminidase (NA) protein of influenza virus strains.

Abstract: The present disclosure provides for a system and method for remote image projection. The system may comprise a compact optical system to provide remote projections of images. The system may comprise an image correction subsystem, an image motion and positioning subsystem, an image relay and deflection subsystem, a source image, a warped image, a remotely projected image. The method may comprise processing the source image with a dewarping algorithm. The image correction subsystem may comprise a source image, a dewarping algorithm. When the system comprises an intermediate image plane, the warped image may be configured to project on the target projection surface upon arrival to the intermediate image plane. The image relay and deflection subsystem may comprise passive mechanical relay optics to refine the remotely projected image and direct the remotely projected image to the target projection surface.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for a lighting controller for sea lice detection. In some implementations, fish are contained within an elliptical tank filled with water. An imaging station located on the elliptical tank is used to capture an image of a fish from which image analysis can be performed to detect sea lice or other skin features, including lesions, on the fish. Pairs of imaging assemblies coordinate pulsing light of at least a first and a second color and capturing images of the fish while the fish is illuminated by at least the first and the second color. By using the captured images with different color light, computers can detect features on the body of a fish including sea lice, skin lesions, shortened operculum or other physical deformities and skin features. Detection results can aid in mitigation techniques or be stored for analytics.

Abstract: Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 or LRP6 binding moiety.

Abstract: A system includes a first body of a fluid-handling component and a second body of a fluid-handling component. The system also includes a fastener configured to couple the first body to the second body, and an annular sleeve configured to surround a portion of the fastener that is positioned at an interface between the first body and the second body when the first body and the second body are coupled to one another.

Abstract: A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R1 is independently selected from the group consisting of H, or halo; each R2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R2 together form —CH?CH— and form part of a polymer backbone; each R3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R4 is aryl; and each R5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.