Abstract: An electrosurgical system includes an electrosurgical generator, a power source configured to deliver power to at least one load connected to the generator, a master configured to generate an initial pulse, and a plurality of slaves connected in series to the master. The initial pulse cooperates with a first floating power supply configured to create an electrical connection between at least one first load and the power source. A first slave is configured to generate a subsequent pulse based on the initial pulse. The subsequent pulse cooperates with a second floating power supply configured to create an electrical connection between at least one second load and the power source. The subsequent pulse is configured to cause an ensuing slave to generate an additional pulse. The additional pulse cooperates with a corresponding floating power supply configured to create an electrical connection between at least one additional load and the power source.

Abstract: An electrosurgical generator may reduce unintended tissue damage by improving regulation of output power. The electrosurgical generator may control the power during a cycle, and react to a change in power if arcing occurs. Voltage sources, especially, demonstrate the tendency to have large, uncontrolled power excursions during normal electrosurgical use. The magnitude of the power excursions may be dependent on various factors. An exemplary electrosurgical generator control scheme reduces or minimizes the thermal spread by accurately supplying the specified power within a few cycles. Additionally, fast and accurate regulation provided by the constant voltage mode reduces or minimizes unintentional tissue charring. Thus, reduced thermal spread and charring should result in better surgical outcomes by reducing scarring and decreasing healing times.

Abstract: A positioning system comprising a mounting assembly arranged to move a positioning device via a magnetic coupling interaction between the mounting assembly and the positioning device. The positioning device is configured to limit the spread of flux away from the device.

Abstract: An electrode assembly for use with an electrosurgical instrument includes a pair of opposing jaw members and an electrode positioned on each jaw member. One or both of the electrodes includes a tissue contacting surface that has an outer periphery and defines a side surface depending therefrom. The tissue contacting surface and the side surface include a conjoining edge formed at a first predetermined angle that defines a first linear transition zone dimensioned to reduce arcing between the opposing jaw members during activation of the electrosurgical instrument.

Abstract: In accordance with one aspect of the present disclosure, a current sensor configured to measure an AC current of a first conductor includes an outer coil having a first portion and a second portion. Each of the first and second portions are disposed about the first conductor passing through a center of the outer coil. The current sensor further includes an inner conductor disposed within the first and second portions of the outer coil and connected to each of the first and second portions of the outer coil.

Abstract: A system for minimizing neuromuscular stimulation includes a converter, an inverter, and a controller. The converter is configured to output a dc waveform and includes at least one first switching element operated at a first duty cycle. The inverter is coupled to the converter and includes at least one second switching element operated at a second duty cycle. The inverter is configured to invert the DC waveform to generate an electrosurgical pulse waveform. The controller is coupled to the converter and the inverter, and is configured to control the first duty cycle to adjust a magnitude of the electrosurgical pulse waveform and the second duty cycle to adjust at least one property of the electrosurgical pulse waveform to minimize neuromuscular stimulation.

Abstract: An electrosurgical generator is presented including a radio frequency (RF) amplifier coupled to an electrical energy source and configured to generate electrosurgical energy, the RF amplifier including an inverter configured to convert a direct current (DC) to an alternating current (AC), and a plurality of sensors configured to sense voltage and current of the generated electrosurgical energy. The electrosurgical generator further includes a controller coupled to the RF amplifier and the plurality of sensors. The electrosurgical may be further configured to determine a power level based on the sensed voltage and the sensed current, determine an efficiency of the electrosurgical generator, and insert a predetermined integer number of off cycles when the efficiency of the electrosurgical generator reaches a threshold power efficiency.

Abstract: An electrosurgical generator is disclosed. The electrosurgical generator includes: a power supply configured to output DC power; an inverter coupled to the power supply, the inverter including a plurality of switching elements; and a controller coupled to the inverter and configured to signal the inverter to simultaneously generate based on the DC power a radio frequency heating waveform and an electroporation waveform.

Abstract: Devices, systems, and methods for promoting hand sanitization which may be mounted above or near a door handle. Hand sanitization devices include a sanitizer agent cartridge disposed inside a housing body and fluidically coupled to an actuating pump. The pump is configured to dispense the sanitizer when an actuation mechanism is pushed or pulled. The cartridge is also coupled to a pump sheath disposed below the pump so as to protect the internal components of the devices from unintentional splashing by the sanitizer agent. The hand sanitization devices may also record when the door is opened, when the sanitizer is dispensed, if the cartridge is empty, and when a user is approaching the door. The hand sanitization devices also have a user interface system configured to encourage the approaching user to sanitize their hands.

Abstract: A controller for an electrosurgical device and related methods and devices are disclosed. The controller has a processing component to: (a) derive a power factor of power applied to the electrosurgical device; and (b) responsive to the deriving a power factor, assign a circuit status to a circuit comprising the electrosurgical device. IF (PF?0) and ((Vrms/Irms)?T), THEN the circuit status is “open”. IF (PF?0) and ((Vrms/Irms)<T), THEN the circuit status is “short”. PF is the power factor. Vrms is the root mean square of a voltage associated with the power applied to the at electrosurgical device. Irms is the root mean square of a current associated with the power applied to the electrosurgical device. T is a threshold value.

Abstract: The present invention is directed to devices, methods and kits for cell-specific sorting of cells from a mixed population, e.g., from a tumor sample. Aspects of the invention combine aligned, electrospun microfibers with drug-or protein-releasing nanospheres to isolate cancer cells from tumor biopsies.

Abstract: A method of improving efficiency of an electrosurgical generator is presented, the method including controlling an output of an electrosurgical generator by converting a direct current (DC) to an alternating current (AC) using an inverter, and sensing a current and a voltage at an output of the inverter. The method further includes the steps of determining a power level based on the sensed voltage and the sensed current, determining an efficiency of the electrosurgical generator, and inserting a predetermined integer number of off cycles when the efficiency of the electrosurgical generator reaches a threshold power efficiency.

Abstract: The present disclosure relates to an electrode assembly for use with an electrosurgical instrument. The electrode assembly includes a pair of opposing jaw members and an electrode positioned on each jaw member. One or both of the electrodes includes a tissue contacting surface that has an outer periphery and defines a side surface depending therefrom. The tissue contacting surface and the side surface include a conjoining edge formed at a first predetermined angle that defines a first linear transition zone dimensioned to reduce arcing between the opposing jaw members during activation of the electrosurgical instrument.

Abstract: A method of operating a resource management node includes, for each of a plurality of resources available in a plurality of distributed computing systems, determining a productive spend metric based on utilization of the resource and cost associated with making the resource available in the distributed computing system. Relocation of workload of selected ones of the resources between the plurality of distributed computing systems is controlled based on the productive spend metrics determined for the selected ones of the resources. Related computer program products and resource management nodes are disclosed.

Abstract: Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.

Abstract: Apparati and methods for dispensing sanitizer fluid via handles on doors and equipment, and data and recording events pertaining to hand sanitization, are disclosed.

Abstract: The present disclosure is directed to an electrosurgical generator including a tank configured to output energy and an H-bridge configured to drive the tank. The generator also includes a choke. The choke impedes a common mode current generated by the H-bridge and provides a leakage inductance for the tank.

Abstract: A generator for use with an electrosurgical device is provided. The generator has a gain stage electrically disposed between a first voltage rail and a second voltage rail, wherein the gain stage includes an input and an output. A voltage source operably coupled to the gain stage input and configured to provide an input signal thereto responsive to a drive control signal is also provided. The generator also has one or more sensors configured to sense an operational parameter of the amplifier and to provide a sensor signal corresponding thereto and a controller adapted to receive the sensor signal(s) and in response thereto provide a drive control signal to the voltage source.

Abstract: A mass spectrometer is disclosed comprising a Time of Flight mass analyzer comprising an ion detector comprising an Analog to Digital Converter. Signals from the Analog to Digital Converter are digitized and the arrival time and intensity of ions are determined. The arrival time T0 and intensity S0 of each ion arrival event is converted into two separate intensities S(n),S(n+i) which are stored in neighboring time bins T(n), T(n+1).

Abstract: Apparatus and methods for dispensing sanitizer fluid via handles on doors and equipment, and data and recording events pertaining to hand sanitization, are disclosed.