Abstract: Methods are disclosed for the production of anti-self antibodies and antibody fragments, being antibodies or fragments of a particular species of mammal which bind self antigens of that species. Methods comprise providing a library of replicable genetic display packages (rgdps), such as filamentous phage, each rgdp displaying at its surface member of a specific binding pair which is an antibody or antibody fragment, and each rgdp containing nucleic acid sequence derived from a species of mammal. The nucleic acid sequence in each rgdp encodes a polypeptide chain which is a component part of the sbp member displayed at the surface of that rgdp. Anti-self antibody fragments are selected by binding with a self antigen from said species of mammal. The displayed antibody fragments may be scFv, Fd, Fab or any other fragment which has the capability of binding antigen. Nucleic acid libraries used may be derived from rearranged V-gene sequences of unimmunised mammal.

Abstract: A method of consolidating genealogy records includes partitioning the records using at least one index file to form one or more partitions, sorting the records in a partition based on a data element in the records, comparing records within a sort range, based on the comparison, identifying same person records, consolidating information in the same person records, receiving a request from a user to view at least a portion of the consolidated information for a particular group of same person records, and sending a file that includes the portion to the user.

Abstract: A method, system, and program for allowing callers to adjust in position within a hold queue are provided. An advancement token earned by a caller while waiting in a hold queue is detected. The advancement token is stored for redemption in a future call by the caller according to an authenticated identifier for the caller, wherein future redemption of the advancement token will cause adjustment of a waiting position. In particular, a caller in the call hold queue may earn advancement tokens by answering questions posed by other callers in the call hold queue, where the questions are answered in a manner such that the other callers do not need additional aid from a representative. In addition, a caller may redeem advancement tokens earned in a previous hold queue while waiting in current hold queue, where the redeemable advancement tokens are accessible across multiple call centers according to the caller identification.

Abstract: A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. Antibody sbp members may be thus obtained, with the different chains thereof expressed, one fused to the capsid component and the other in free form for association with the fusion partner polypeptide. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.

Abstract: A method, system, and program for origin device initiated callee identification are provided. At an origin device, a voice utterance of a callee is detected from a destination device. A callee identity associated with the voice utterance is identified at the origin device, such that the callee identity is transmittable as an authenticated identity of the callee for a call. A caller may select whether to continue a call dependent upon whether the callee identity is preferable. In addition, an intermediary device may receive the callee identity and specify services available during the call according to the callee identity.

Abstract: A method, system, and program for estimating hold queue wait times are provided. Call times are individually estimated for multiple calls within a call center. In particular, call times may be estimated according to representative profiles, caller profiles, and current caller activity of the multiple calls within the call center. The identity of each caller may be authenticated and a caller profile accessed from a central server according to authenticated caller identities. The central server may be accessible to multiple call centers, where each call centers accesses and updates caller profiles according to a single caller identifier for each caller. In addition, call times estimates and factors utilized to calculate call time estimates may be output to a caller, preferably according to an output interface specified by the caller in the caller profile.

Abstract: A method, system, and program for time based regulation of access to callees are provided. An authenticated identity of a caller placing a call is preferably detected. Then, a communication link from the caller to a callee is only attempted if the authenticated identity of the caller is allowed access to the callee according to a schedule associated with an identity of the callee.

Abstract: A method, system, and program for intermediary device initiated callee identification are provided. A trusted telephone network detects a call receipt connection from a destination device. The trusted telephone network then brokers a connection between the destination device and an external server enabled to perform a callee identity authentication service. A voice utterance for a callee is received at the external server from the destination device. The server authenticates a callee identity associated with the voice utterance and transfer the authenticated callee identity to the trusted telephone network. The trusted telephone network then specifies services available for the call according to a callee profile for the authenticated caller identity.

Abstract: A method, system, and program for billing a caller for use of an origin device are provided. Usage, of at least one measurable element of a telephony device by an identified individual, is tracked, where the identified individual is distinct from an owner of the origin telephony device. A tariff for the tracked usage is transferred to an intermediary device. The intermediary device charges the tariff according to a billing plan for the identified individual, such that the owner is compensated for use of at least one measurable element of the owner's telephony device. Measurable elements may include the time the telephony device is in the identified individual's possession, the battery usage, and usage of the address book.

Abstract: This invention provides for novel human antibodies that specifically bind to c-erbB-2. The antibodies may be used alone or as components of chimeric molecules that specifically target and deliver effector molecules to cells overexpressing c-erbB-2.

Abstract: A method, system, and program providing identification usage fraud protection are provided. A context for a use of an identification via a communication line is detected at a fraud protection service. The context for use of the identification is analyzed in view of multiple previous uses of the identification. A level of suspicion of fraudulent use of the identification is specified according to the analysis of the context. Depending on the level of suspicion, further use of the identification may require additional authentication or may be barred. The identification may include a user name, an account number, a password, or other identifier that may be utilized to represent an individual in accessing products and services.

Abstract: A method for detecting unreliable response conditions in a plurality of back-end transaction processing systems also can include the steps of: reading a list of references to a plurality of subscribing e-commerce systems; generating and dispatching placebo transactions to each e-commerce system in the list; receiving responses to the dispatched placebo transactions; computing transaction latency data based upon when each placebo transaction is dispatched to a subscribing e-commerce system, and when a corresponding response is received; and, notifying individual subscribing e-commerce systems when computed transaction latency data for the individual subscribing e-commerce systems indicates an unreliable response condition in an associated back-end transaction processing system.

Abstract: This invention provides methods of identifying ligands that are internalized into a cell. The methods typically involve i) contacting the cell with a reporter non-covalently coupled to a ligand; ii) dissociating the reporter from the ligand and removing dissociated reporter from the surface of the cell; and iii) detecting the reporter within said cell (if any is present) where the presence of the reporter within said cell indicates that the ligand binds to an internalizing receptor and is internalized.

Abstract: A method, system, and program for promoting use of experts to callers waiting within a hold queue are provided. First, use of experts by callers waiting in a hold queue is promoted by offering callers an incentive to speak to an expert while waiting to speak with an official representative. The caller continues to progress in the hold queue while speaking with an expert. In addition, the caller may receive an additional adjustment in the hold queue, a financial incentive, and a rewards points incentive, for interacting with an expert while holding. Second, use of experts by callers waiting in a hold queue is promoted by authenticating the identity of third party experts, in order to verify that an expert has the skills needed to help a caller and to provide the caller with the identity of the expert for accountability.

Abstract: A system, system, and program for identifying a call made or received on behalf of another are provided. In particular, a call request for a call is detected. A context for the call is requested from a context inference service, wherein the context indicates whether an on behalf of action is invoked for the call by the caller or callee. An on behalf of action may be requested by a caller or callee, automatically authorized by the on behalf of party, or inferred from other call context.

Abstract: A universal reusable template for cutting ends of cylindrical objects such as pipes, in preparation for joining the cylindrical objects to other cylindrical bodies. The template is formed as a flat flexible bendable sheet with magnetic properties allowing the sheet to be temporarily secured on a metal pipe. The front face of the sheet has reference indicia corresponding to contour lines of a desired cut to be made in the end of the cylindrical body. The cut lines represent most conventional types and sizes of lateral-type cuts, eccentric cuts and saddle-type cuts, with pipe diameters ranging from about 3? to about 24?.

Abstract: A method, system, and program for identifying a context for a call are provided. Multiple context clues for a call are detected from a line number, a line subscriber profile, a caller profile, and other parameters associated with the call. A context for the call is identified from the context clues, such that at least one party to the call is enabled to receive the context of the call. Context for the call preferably includes at least one of who is placing a call, who is receiving a call, identities of devices utilized for the call, locations of those devices, the path of line number numbers accessed for a call, a billing plan for the call, and a subject matter of the call.

Abstract: A method, system, and program for managing caller profiles across multiple hold queues according to authenticated caller identifiers are provided. An identity of a caller of a call received at an on hold system is authenticated. The call is then placed in a hold queue. A caller profile associated with the identity of the caller is retrieved, such that services available to the caller while on hold are specified according to the caller profile. In particular, the caller profile is preferably retrieved from at least one caller profile server according to the caller identifier, where the at least one caller profile server is accessible to multiple on hold systems. Further, the identity of a caller may be authenticated by authenticating a voice sample received from the caller, such that a single identity for the caller may be authenticated at multiple call centers.

Abstract: A method, computer program product, and program for originating a billed transaction at an origin telephony device are provided. A request to originate a billed transaction is received from an origin device. The identity of a callee answering a call originated by the origin device is authenticated. Responsive to receiving an acceptance of the call by the callee, an account accessed by the authenticated identity of said callee is billed to complete said billed transaction, such that the origin device is enabled to initiate the billed transaction charged to the callee. In particular, a service associated with the billed transaction may only available for a particular callee or selection of callees. In addition, the callee may elect which account to charge for the billed transaction. Further, the identity of the caller originating the call at the origin device is forwarded to the callee.

Abstract: A method, system, and program for time based regulation of use of a telephone line are provided. An identity of a first caller requesting use of a telephone line is detected. Use of the telephone line by the caller is allowed only if a schedule for the telephone line indicates that the identity is currently allowed for the telephone line.