Abstract: Generating and validating a subscription key based on subscription parameters associated with a jurisdiction file stored in a NVRAM, the subscription key having characters based on a subscription start date, a subscription term, a key generation date, and a cyclical redundancy check value. Parameters are extracted from the subscription key including the subscription start date, the subscription term, the key generation date, and the cyclical redundancy check value and are stored in a memory of the gaming machine. The key is checked by generating a local cyclical redundancy check value based on a MAC address of the gaming machine and one or more of the extracted parameters, and is validated when the local cyclical redundancy check value matches the cyclical redundancy check value extracted from the subscription key. The jurisdiction file may be updated during a RAM clear function during installation of the gaming machine.

Abstract: Connections among two different entities are identified by processing a collection of documents to identify one or more documents that contain co-occurring mentions of each of the two different entities. This relationship may be graphically displayed in a user interface with an icon or the like for each of the two entities, along with a graphical link interconnecting the entities. The graphical link can be an active element of the user interface that responds to user interactions by providing access to evidence within the collection of documents that substantiates the connection between the two entities. In one aspect, a search input form field in a user interface may be used to explicitly request documents that substantiate a relationship between two entities. In another aspect, a user may ground entity mentions by explicitly selecting documents that mention an entity of interest.

Abstract: An end effector assembly includes a clevis having first and second spaced-apart arms, a ceiling, a floor, pivot and cam pins extending between the arms, and first and second jaw members. Each jaw member includes a proximal portion and a distal body extending distally from the clevis. The proximal portion of the first jaw member includes a first flag disposed between the first and second arms of the clevis, operably coupled to both the pivot pin and the cam pin, extending vertically at least partially through openings defined within the ceiling and floor. The proximal portion of the second jaw member includes second and third flags disposed between the first and second arms of the clevis in spaced-apart relative to one another and between the ceiling and the floor. The second and third flags are fixedly engaged to the clevis.

Abstract: A system, method, and computer-program product includes obtaining, via a graphical user interface: an input of a measured unit distribution derived from measurements, by a measuring device, of a plurality of instances of a physical unit; an input of characteristics of the measuring device used in the measurements of the plurality of instances of the physical unit; and an input of a type of distribution for fitting a set of measurement values of the physical unit to a target distribution; computing, via a unit distribution estimation algorithm, an estimated true unit distribution of the plurality of instances of the physical unit based on (a) the input of the measured unit distribution, (b) the input of the characteristics of the measuring device, and (c) the input of the type of distribution; and using quantitative characteristics of the estimated true unit distribution to mitigate binning classification error of the physical units.

Abstract: An adversarial reinforcement learning system is used to simulate a spatial environment. The system includes a simulation engine configured to simulate a spatial environment and various objects therein. The system further includes a first model configured to control objects in the simulation and a second model configured to control objects in the simulation. The first model generates a threat-mitigation input to control one or more objects in the simulation, and the second model generates a threat input to control one or more objects in the simulation. The system then executes a first portion of the simulation based at least in part of the threat mitigation input and the threat input.

Abstract: A robotic surgical instrument includes a housing, a shaft assembly extending distally from the housing, and an end effector assembly. The shaft assembly has a proximal segment coupled to the housing, a clevis supporting the end effector assembly, and at least one articulating link pivotably coupled to and interconnecting the proximal segment and the clevis such that the end effector assembly is configured to articulate relative to the proximal segment via the at least one articulating link in at least two directions.

Abstract: A robotic surgical instrument includes a housing, a support plate disposed within the housing, and a shaft having a proximal end portion coupled to the support plate within the housing, a proximal segment, a distal segment, and an articulating portion interconnecting the proximal and distal segments. An end effector assembly is coupled to the distal segment of the shaft. A plurality of actuation components extends through the support plate and at least a portion of the shaft to operably couple to at least one of the end effector assembly, the articulating portion, or the distal segment to enable selective actuation of the end effector assembly. A seal configuration establishes seals against an interior annular surface of the shaft, about each actuation component of the plurality of actuation components, and within the proximal end portion of the shaft to inhibit fluid communication from the shaft into the housing.

Abstract: A one-way valve is provided. The valve provides a housing with a through hole having an upstream portion and a downstream portion. The upstream portion has a reduced diameter compared to the downstream portion. The housing contains a valve seat. A valve member, or poppet, moves within the through hole from a valve closed position and a valve open position. A low pressure facing side of the poppet engages an elastic member of a compression member that biases the poppet in the valve closed position. A high pressure facing side of the poppet engages a resilient metal seal in the form of an annular disc, which may have a generally wavy or undulating shape. The outer ends of the resilient metal seal are curved to releasably engages the valve seat.

Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user.

Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user.

Abstract: A one-way valve is provided. The valve provides a housing with a through hole having an upstream portion and a downstream portion. The upstream portion has a reduced diameter compared to the downstream portion. The housing contains a valve seat. A valve member, or poppet, moves within the through hole from a valve closed position and a valve open position. A low pressure facing side of the poppet engages an elastic member of a compression member that biases the poppet in the valve closed position. A high pressure facing side of the poppet engages a resilient metal seal in the form of an annular disc, which may have a generally wavy or undulating shape. The outer ends of the resilient metal seal are curved to releasably engages the valve seat.

Abstract: Fluid delivery devices, systems and methods. The fluid delivery devices may be used to delivery fluid (e.g., insulin) to a user. The devices may have one or more inlets, and may be configured for use with an injection device, such as a syringe, and/or with a pump.

Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user.

Abstract: Compositions and methods for inducing pluripotent stem cells into retinal ganglion cells for administration to a subject for treating progressive optic neuropathies, thereby alleviating symptoms of such disorders including glaucoma.

Abstract: A one-way valve is provided. The one-way valve may be, for example, a check valve, a relief valve, or the like, which may be in the form of a poppet valve. The valve provides a housing with a through hole. The through hole has an upstream portion and a downstream portion. The upstream portion has a reduced diameter compared to the downstream portion. The housing contains a valve seat, which typically has a taper. A poppet, or valve member, moves within the through hole from a valve closed position and a valve open position. The poppet has a high pressure facing side and a low pressure facing side opposite the high pressure facing side. The low pressure facing side of the poppet engages an elastic member of a compression member that biases the poppet in the valve closed position. The high pressure facing side of the poppet engages a resilient metal seal in the form of an annular disc. The annular disc has a generally wavy or undulating shape.

Abstract: An adversarial reinforcement learning system is used to simulate a spatial environment. The system includes a simulation engine configured to simulate a spatial environment and various objects therein. The system further includes a first model configured to control objects in the simulation and a second model configured to control objects in the simulation. The first model generates a threat-mitigation input to control one or more objects in the simulation, and the second model generates a threat input to control one or more objects in the simulation. The system then executes a first portion of the simulation based at least in part of the threat mitigation input and the threat input.

Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user.

Abstract: An adversarial reinforcement learning system is used to simulate a security checkpoint. The system includes a simulation engine configured to simulate a security checkpoint and various threat objects and threat-mitigation objects therein. The system further includes an attack model configured to control threat objects in the simulation and a defense model configured to control threat-mitigation objects in the simulation. A first portion of the simulation is executed by the simulation engine in order to generate an outcome of the first portion of the simulation. The defense model then generates a threat-mitigation input to control threat-mitigation objects in a subsequent portion of the simulation, and the attack model then generates a threat input to control threat objects in the subsequent portion of the simulation, wherein the inputs are based in part on the outcome of the first portion of the simulation.

Abstract: A turbine nozzle includes an airfoil shape. The airfoil shape may have a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table I. The Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances in inches by multiplying the Cartesian coordinate values of X, Y and Z by a height of the airfoil in inches. The X and Y values, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z. The airfoil profile sections at Z distances may be joined smoothly with one another to form a complete airfoil shape.

Abstract: Generating and validating a subscription key based on subscription parameters associated with a jurisdiction file stored in a NVRAM, the subscription key having characters based on a subscription start date, a subscription term, a key generation date, and a cyclical redundancy check value. Parameters are extracted from the subscription key including the subscription start date, the subscription term, the key generation date, and the cyclical redundancy check value and are stored in a memory of the gaming machine. The key is checked by generating a local cyclical redundancy check value based on a MAC address of the gaming machine and one or more of the extracted parameters, and is validated when the local cyclical redundancy check value matches the cyclical redundancy check value extracted from the subscription key. The jurisdiction file may be updated during a RAM clear function during installation of the gaming machine.