Abstract: Systems and methods for aggregating data. The system is configured to receive metadata from an interactive graphical user interface (GUI) of a user device, aggregate field values from the data stored on one or more databases based on the received metadata and generate filter instructions based on the received metadata. The system is further configured to transmit the aggregated field values and the filter instructions to the user device, receive a user-customized filter set and subscription request for a synthetic symbol associated with the user-customized filter set from the user device, and create the synthetic symbol responsive to the subscription request. Moreover, the system aggregates one or more data values from the data stored on the databases associated with the created synthetic symbol and generates instructions to display the data values on the interactive GUI in accordance with the user-customized filter set associated with the created synthetic symbol.

Abstract: A tiltenator of a media separator module (integrated within a valuable media depository) adaptively controls pressure maintained against a bunch of media as individual items from the bunch are fed through the media separator module.

Abstract: A method for delivering media to a playback device including outputting first test media to be viewed by a first user. The method further includes receiving a first user input related to a first perception of the first test media by the first user and indicating a first personalized quality of experience of the first user with respect to the first test media. The method further includes generating a first personalized sensitivity profile including one or more viewing characteristics of the first user based on the first user input, and determining, based at least in part on the first personalized sensitivity profile, a first media parameter. The first media parameter is determined in order to increase an efficiency of media delivery to the first playback device over a network while preserving the first personalized quality of experience of the first user.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: Method and apparatus for preparing at least one metal chloride from metal oxide containing material comprising calcining the metal oxide containing material under temperature conditions sufficient to obtain a calcined product comprising at least one metal oxide; and selectively chlorinating the calcined product to form at least one metal chloride.

Abstract: A method includes obtaining a help file including steps for a task and generating a knowledge graph including instructions corresponding to the steps. The method further includes extracting, from a user input of a user, an intent to complete the task. Responsive to extracting the intent to complete the task, obtaining the knowledge graph is obtained. Using the knowledge graph, an instruction of the knowledge graph is presented to perform an action in a workflow to complete the task.

Abstract: The disclosure provides compositions comprising novel adenosine base editors (e.g., ABE8) that have increased efficiency and methods of using these adenosine deaminase variants for editing a target sequence.

Abstract: A novel maize variety designated X18N926 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X18N926 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18N926 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X18N926, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18N926 are provided. Methods for producing maize varieties derived from maize variety X18N926 and methods of using maize variety X18N926 are disclosed.

Abstract: Systems and methods for generating a data aggregator interactive graphical user interface. An interactive graphical user interface (GUI) includes a selectable symbol region, a query region and a data results region. The selectable symbol region displays predefined symbols. The query region displays user input fields for generating queries. The system receives user input associated with the user input fields of the query region to form a filter set. The data results region is automatically updated responsive to the user input, to display one or more data values from among one or more databases associated with the filter set. The system receives a subscription request to save the filter set as a user-customized query. A custom symbol is created responsive to the subscription request that is associated with the filter set. The the selectable symbol region is updated to display the custom symbol together with the predefined symbols.

Abstract: Systems and methods are provided for vector-quantized image modeling using vision transformers and improved codebook handling. In particular, the present disclosure provides a Vector-quantized Image Modeling (VIM) approach that involves pretraining a machine learning model (e.g., Transformer model) to predict rasterized image tokens autoregressively. The discrete image tokens can be encoded from a learned Vision-Transformer-based VQGAN (example implementations of which can be referred to as ViT-VQGAN). The present disclosure proposes multiple improvements over vanilla VQGAN from architecture to codebook learning, yielding better efficiency and reconstruction fidelity. The improved ViT-VQGAN further improves vector-quantized image modeling tasks, including unconditional image generation, conditioned image generation (e.g., class-conditioned image generation), and unsupervised representation learning.

Abstract: In various embodiments, a carrying bag is disclosed which includes a one or more security panel assemblies comprising a first flexible material layer and a polymeric fiber matrix, such as a polymer fiber-based cut-resistant fabric, matrix or mesh. Various carrying straps are disclosed which include a first flexible fabric or webbing; and a second flexible fabric or webbing comprising a polymeric fiber matrix. Additional polymeric fibers, filaments, cables, threads or yarns may be included in the security panel assemblies and straps, such as cut-resistant monofilament and multifilament fibers comprised of a polyethylene such as ultra high molecular weight polyethylene (UHMAWPE), high-modulus polyethylene (HMPE), or High Performance Polyethylene (HPPE), for example.

Abstract: A method comprises: by a controller to communicate with devices of a network, storing classifiers assigned to groups of the devices to identify device commonality for each group; associating, to the classifiers, historical probabilities of success with which an automated response executed by one or more of the devices remediates a device alarm event; when a device of the devices reports the device alarm event, identifying each classifier to which the device belongs, each historical probability for each classifier, and a rule with classifier thresholds for the automated response; determining to execute the automated response on the device by evaluating the rule using each historical probability and the classifier thresholds; after the automated response is executed, performing a service test supported across the devices, and monitoring test results from the service test; and after the service test, updating each historical probability using the test results.

Abstract: Systems and methods for aggregating data. The system is configured to receive metadata from an interactive graphical user interface (GUI) of a user device, aggregate field values from the data stored on one or more databases based on the received metadata and generate filter instructions based on the received metadata. The system is further configured to transmit the aggregated field values and the filter instructions to the user device, receive a user-customized filter set and subscription request for a synthetic symbol associated with the user-customized filter set from the user device, and create the synthetic symbol responsive to the subscription request. Moreover, the system aggregates one or more data values from the data stored on the databases associated with the created synthetic symbol and generates instructions to display the data values on the interactive GUI in accordance with the user-customized filter set associated with the created synthetic symbol.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: This disclosure provides a wearable point-of-care (POC) device for assessing immune activity in a subject in need thereof, the device comprising: a microneedle patch capable of making conformal contact with a skin of the subject, the microneedle patch comprising a plurality of microneedles: a lateral flow test strip comprising a plurality of channels, each of the channels in the plurality of channels comprising control and capture antibodies for an analyte in a plurality of analytes, wherein the control and capture antibodies are deposited along a length of the channel such that upon exposure to the analyte a number of visible spots in the channel is correlated with a concentration of the analyte; and a means for pumping an interstitial fluid from the plurality of microneedles and through each of the channels in the plurality of channels when the device is on the skin of the subject.

Abstract: Methodologies to detect off-target mutations induced by the deaminase activity of Base Editing technology.

Abstract: An apparatus and methods for characterizing and communicating carbon dioxide presence in a subterranean formation traversed by a wellbore including collecting fluid from the wellbore at a wellhead, analyzing the fluid for the presence, concentration, or both of the carbon dioxide using an instrument connected to a line collecting the fluid from the wellhead, and communicating the instrument analysis information within 24 hours of analyzing the fluid. Some embodiments may control the introduction of carbon dioxide into the formation. An apparatus and methods for monitoring the presence of carbon dioxide in a fluid produced from a wellbore including continuously collecting and conditioning a sample line from a wellbore, analyzing the sample line with an instrument at the wellsite, recording information from the analyzing continuously over time, and controlling the collecting, conditioning, analyzing, and recording with a process control device.

Abstract: In some examples, a method includes bonding a multilayered filter medium comprised of at least one layer of filter membrane and at least one support layer web material by bonding along a perimeter of the filter web while concurrently slitting the multilayered filter medium. Further, some examples include a filter element comprising a multilayered filter medium with at least one first layer of a filter membrane or a meltblown material, and at least one support layer web material as a second layer, wherein the at least one first layer and the at least one second layer are bonded and sealed to each other along a perimeter thereof.

Abstract: An image of a sample collection device is captured. The image of the sample collection device is analyzed to determine whether the sample collection device includes a sufficient amount of fluid sample. The image of the sample collection device is validated based on a result of the image analysis.

Abstract: Described herein are pharmaceutical compositions comprising one or more fumarate esters and methods for treating multiple sclerosis subjects with the compositions where the incidence of gastrointestinal side effects is reduced compared to treatments comprising dimethyl fumarate (e.g., TECFIDERA®). In particular, described herein are oral pharmaceutical compositions comprising monomethyl fumarate in a liquid vehicle that have reduced gastrointestinal side effects.