Abstract: Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.

Abstract: The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

Abstract: A system and/or method may be provided to authenticate a user. An example method of authenticating a user includes receiving, by a merchant application, a user request to complete a transaction using a payment service provider. The method also includes in response to receiving the user request to complete the transaction, retrieving, by the merchant application, a browser cookie stored on a user device and associated with one or more user interactions with a browser included in the user device and the payment service provider. The method further includes in response to receiving the user request to complete the transaction, launching, by the merchant application, an instance of the browser that reads the browser cookie and authenticates the user based on the browser cookie.

Abstract: A magnetic resonance apparatus which may include: a body portion having a cavity with a first and second ends and at least one opening situated at one of the first and second ends. The cavity may define a longitudinal axis (LA) extending between the first and second ends. At least one main magnet may generate a main magnetic field having a substantially homogenous magnetic field within the cavity. A center shim (CS) which may be formed from a ring having opposed edges and which may extend along a length of the longitudinal axis of the cavity. One or more discrete shims (DSs) may be situated between the CS and at least one of the first and second ends.

Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.

Abstract: A method, computer program product, and apparatus are provided for controlling components of a detection device. The device may detect turbidity of liquid with sensors such as a density sensor and/or nephelometric sensor. A light modulation pattern may reduce or eliminate interference in sensor readings. Readings may be performed during off cycles of an illumination light to reduce interference but to provide improved visibility of a tube. Dark and light sensor readings may be performed with an emitter respectively off or on to account for ambient light in subsequent readings. Readings from the density sensor and/or nephelometric sensor may be used to calculate McFarland values. The device may be zeroed based on an emitter level that results in a sensor reading satisfying a predetermined criterion.

Abstract: Using a first key, an encrypted file fingerprint is decrypted, the decrypting resulting in a decrypted file fingerprint. Using a hash function on a script file, a script file fingerprint is computed, the script file intended to be executed by an interpreter. Responsive to the script file fingerprint matching the decrypted file fingerprint, the script file is executed.

Abstract: A method for purifying a viral vector from a solution including the viral vector and host cell proteins (HCP) is provided. The method includes circulating the solution across an ultrafiltration/diafiltration membrane using tangential flow filtration (TFF) mode with continuous addition of diafiltration buffer. The method further includes filtering the solution across the ultrafiltration/diafiltration membrane to provide a permeate and a retentate. The retentate is collected such that a purified viral vector solution is obtained and retained in the retentate. A volume of the retentate is kept constant by the continuous addition of diafiltration buffer and the HCP is filtered out via the permeate.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. A system may include assembly cells each including an assembly track and assembly carriages that ride thereon and which engage components of partially-assembled cartridges. A transfer apparatus may transfer partially-assembled cartridges between the assembly cells. In another example system, cartridges may be assembled on platforms on a rotary track. The platforms may include assembly grippers with sequentially-opening clamps configured to receive the components of the partially-assembled cartridges. Related methods are also provided.

Abstract: In a power steering system employing an end of travel system including valve actuating rings disposed about a Pitman arm shaft, a device is provided for setting the positions of the rings on the shaft. The device includes a fixed member positioned about, and fixed against movement along, a longitudinal axis perpendicular to the shaft's rotational axis and a movable member that moves along the longitudinal axis relative to the fixed member. The movable member defines a pin at one end configured for engagement with the circumferential ends of the actuating rings. A positioning force applied to one of the members causes the movable member to move between set and reset positions in which the pin engages corresponding ends of the actuating rings during rotation of the shaft and a running position in which the pin remains disengaged from the ends of the actuating ring during rotation of the shaft.

Abstract: An example extraction device may include a generally tubular shaft including a distal end configured to be inserted into a patient and a proximal end configured to be retained exteriorly of the patient; a basket extending from the distal end of the shaft, the basket including a plurality of flexible, distally extending legs, the legs including respective distal ends that are biased generally radially outward to at least partially define a basket distal opening; a handle disposed at the proximal end of the shaft; an actuator disposed on the handle; and/or a closure line operatively coupled to the actuator, the closure line extending distally through the shaft, through a closure line guide disposed on the distal end of the shaft, and generally circumferentially about the basket distal opening, the closure line being slidably coupled to each leg near its respective leg distal end.

Abstract: Systems and methods of threading a metal substrate on a rolling mill include receiving a coil of the metal substrate. The method also includes uncoiling the metal substrate from the coil while the coil and guiding the metal substrate to a work stand of the rolling mill with a threading system.

Abstract: Provided is a seal clamp assembly for sealing a female and male member together. The seal clamp assembly includes a seal configured to be positioned over the female and male members, the seal having a first end, a second end opposite the first end, a first edge, and a second edge opposite the first edge, and a retainer configured to be positioned over the seal, the retainer having a first end, a second end opposite the first end, a first edge, and a second edge opposite the first edge, wherein the retainer has a serpentine configuration along its length.

Abstract: A grommet includes a body portion defining a first aperture and a second aperture. A hollow channel extends between the first aperture and the second aperture. The channel is defined by an interior surface of the body portion. One or more engagement structures are defined by the interior surface of the grommet body portion, and are configured to engage one or more corresponding engagement structures provided about an exterior surface of a mounting structure engaged about and elongated member that is positioned within the hollow channel of the grommet.

Abstract: Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.