Abstract: The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

Abstract: An affordable tension device for maintaining tension on a wire rope of a cable-based lifting system is provided. The tension device has an elongated casting weight adapted to govern the casting weight as it rides along a predetermined wire rope for maintaining tension thereon. The tension device provides a clevis with a sheave for operatively associating with the tension wire rope.

Abstract: A system and method for annealing a target substrate such as a semiconductor using industrial microwave heating and parallel plate reaction. Using a uniform microwave field, with the target substrate located between parallel plates controls application of eddy currents to the target substrate. The system may include a uniform microwave field generator, support elements, two plates held in parallel to each other, and a turntable device configured to rotate the two plates and the target substrate within the uniform microwave field. The rotating of the plates and target substrate in the uniform microwave field creates a periodic change in polarity of the microwaves applied to the target substrate. The eddy currents in the uniform microwave field react by flowing perpendicular to the plates, and not parallel to the surface as in traditional microwave reactions of metals. This redirection of the eddy currents provides even heating of the target substrate.

Abstract: A magnetic resonance apparatus which includes: a body portion (102) having a cavity (106) with a first and second ends and at least one opening situated at one of the first and second ends. The cavity may define a longitudinal axis (LA) extending between the first and second ends. At least one main magnet may generate a main magnetic field having a substantially homogenous magnetic field within the cavity. A center shim (CS) which may be formed from a ring having opposed edges (131) and which may extend along a length of the longitudinal axis of the cavity. One or more discrete shims (DSs) may be situated between the CS and at least one of the first and second ends.

Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.

Abstract: The disclosure relates to methods of using obeticholic acid or pharmaceutically acceptable salt or amino acid conjugate thereof for slowing down or reversing the progression of compensated cirrhosis.

Abstract: The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

Abstract: Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.

Abstract: A hybrid transaxle permits location of a traction motor in a more favorable location, decreasing the risk of occupant injury in a vehicle collision. Axis transfer gearing moves the generator off the engine axis, which permits placing the traction motor further forward without interference with the generator. The gearing is confined to two gear planes, reducing the transaxle width.

Abstract: A vaporizer cartridge system includes a vaporizer assembly containing a heating element, a mouthpiece that is selectively attachable with the vaporizer assembly, a battery assembly that is selectively attachable with the vaporizer assembly, and a cartridge configured to store liquid in a reservoir, the cartridge being selectively attachable with the vaporizer assembly such that liquid stored within the reservoir is in fluid communication with the vaporizer assembly. The vaporizer cartridge system is configured such that when the cartridge and the mouthpiece are attached to the vaporizer assembly, the cartridge fits within the mouthpiece.

Abstract: The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

Abstract: The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

Abstract: The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions.

Abstract: A portable structure including a base, a first wall panel and a second wall panel. The base includes a first post and a second post. The first wall panel includes a first outer corner extrusion and a second outer corner extrusion, the first outer corner extrusion adapted to partially enclose the first post and the second outer corner extrusion adapted to partially enclose the second post. The second wall panel includes a first inner corner extrusion adapted to fully enclose the first post when used in combination with the first outer corner extrusion.

Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. A system may include assembly cells each including an assembly track and assembly carriages that ride thereon and which engage components of partially-assembled cartridges. A transfer apparatus may transfer partially-assembled cartridges between the assembly cells. In another example system, cartridges may be assembled on platforms on a rotary track. The platforms may include assembly grippers with sequentially-opening clamps configured to receive the components of the partially-assembled cartridges. Related methods are also provided.

Abstract: Systems and methods allow a user to interact with an augmented reality device. In one implementation, a wearable device for providing a virtual menu to a user includes a display; at least one sensor configured to provide an output indicative of a viewing direction the user; and at least one processing device. The at least one processing device is configured to cause a virtual menu to be shown on the display; monitor a viewing direction of the user based on the output of the at least one sensor; determine, based on the monitored viewing direction, whether the user is looking in a direction of a selectable element of the virtual menu; determine an amount of time that the user looks in the direction of the selectable element; and cause at least one action associated with the selectable element if the amount of time exceeds a predetermined dwell time threshold.

Abstract: Systems and methods of threading a metal substrate on a rolling mill include receiving a coil of the metal substrate. The method also includes uncoiling the metal substrate from the coil while the coil and guiding the metal substrate to a work stand of the rolling mill with a threading system.

Abstract: The present disclosure provides embodiments of a virtual draft framework that can be used to provide a controlled randomized virtual draft process by using virtual profile groups to selectively control the amount of randomness during the virtual draft process. The virtual draft can include of a predetermined number of rounds. In each round one or more virtual players can be drafted to a virtual team. Each draft round can provide a player with the opportunity to select a virtual characters that will be used within the game application.