Abstract: An embodiment of a semiconductor device comprises a SiC semiconductor body, a gate dielectric and a gate electrode. A first trench extends from a first surface of the SiC semiconductor body into the SiC semiconductor body. A junction material is in the first trench, wherein the junction material and the SiC semiconductor body form a diode.

Abstract: A computer-implemented method for generating a corresponding 3D mesh representing a 3D object includes transforming an initial three-dimensional mesh into a planar mesh, wherein each vertex or edge of the planar mesh is a transformation of a vertex or edge from the initial three-dimensional mesh; and sampling the planar mesh to generate a plurality of samples such that each sample comprises a three-dimensional coordinate representing a point in a three-dimensional space derived and/or taken directly from the initial three-dimensional mesh, and a coordinate representing a position of the sample relative to other samples; and generating the sampled matrix based on the plurality of samples; and representing the sampled matrix as a corresponding 3D mesh.

Abstract: In order to avoid chronic damage for people performing physical labor and to support the execution of activities, an exoskeleton is provided as a support device with a device for implementing rotational and translational human movements. The exoskeleton, which is coupled to at least one body part of a person, comprises at least one man-technology interface, a device for implementing rotational and translational human movements, and an actuating unit which, under certain circumstances, is supplemented by a sensor system and a controller.

Abstract: Example posture analysis systems and methods are described. In one implementation, a computing system identifies a deviation of a user's posture from a predetermined posture based on visual data associated with the user. The user is informed of the deviation via a graphical image displayed on a display device. The user is then provided with instructions for correcting the deviation via the graphical image displayed on the display device.

Abstract: The present disclosure is directed to reducing nocturnal voids by administering a dose of desmopressin over a minimum treatment period compared to before administration, and maintaining or improving the reduction of nocturnal voids over the minimum treatment period.

Abstract: Methods are provided for treatment of cutaneous T cell lymphoma with an effective dose of an anti-CD47 agent, optionally combined an additional anti-cancer agent.

Abstract: The invention is directed to a barrier layer for corrosion protection in electrochemical devices, e.g. carbon based gas diffusion layers (GDLs) in electrochemical devices, comprising electrically conductive ceramic material and a non-ionomeric polymer binder. The electrically conductive ceramic material has an electrical conductivity of >0.1 S/cm, preferably >1 S/cm in air atmosphere (as detected by the powder method) and is selected from the group of precious metal and/or base metal containing oxides, carbides, nitrides, borides and mixtures and combinations thereof. Membrane-electrode assemblies (MEAs), catalyst-coated membranes (CCMs), gas diffusion electrodes (GDEs) and gas diffusion layers (GDLs) comprising the barrier layer of the invention show improved corrosion resistance, preferably against carbon corrosion; particularly in start-up/shut-down cycles and fuel starvation situations of PEM fuel cells.

Abstract: A method of manufacturing a semiconductor device is proposed. A silicon carbide, SiC, semiconductor body is provided. Ions are introduced into the SiC semiconductor body through a first surface of the SiC semiconductor body by at least one ion implantation process. Thereafter, a SiC device layer is formed on the first surface of the SiC semiconductor body. Semiconductor device elements are formed in or over the SiC device layer.

Abstract: A method for improving the accuracy of a digital medical model of a part of a patient, the method includes obtaining a set of at least 2 medical images of the patient, where an element including a predefined geometry and/or predefined information was attached to the patient during the recording of the medical images; obtaining at least 2 tracking images taken with at least one camera having a known positional relationship relative to the medical imaging device, the tracking images depicting at least part of the element; determining any movement of the element between acquisition of the at least 2 tracking images; and generating the digital medical model from the acquired medical images, wherein the determined movement of the element is used to compensate for any movement of the patient between the acquisition of the medical images.

Abstract: A semiconductor device includes a contact metallization layer that includes aluminum and is arranged on a semiconductor substrate, an inorganic passivation structure arranged on the semiconductor substrate, an organic passivation layer comprising a first part that is arranged on the contact metallization layer, and a second part that is arranged on the inorganic passivation structure, a first layer structure including a first part that is in contact with the contact metallization layer, a second part that is contact with the inorganic passivation structure, and a third part that is disposed on the semiconductor substrate laterally between the inorganic passivation structure and the organic passivation layer.

Abstract: A method uses a flexible endoscope to inspect one or more hard-to-reach components of a gas turbine. The flexible endoscope has at least one image capture unit, which is configured to capture visual image information and associated 3D data, and which is located at a free end of the flexible endoscope. The method includes: introducing the flexible endoscope through an inspection opening; capturing the visual image information and the associated 3D data by the at least one image capture unit; comparing the captured 3D data to a 3D model of a component to be examined, and based on the comparison, ascertaining a relative pose of the at least one image capture unit in relation to the component; and texturing the 3D model with the visual image information captured by the at least one image capture unit, in accordance with the ascertained relative pose of the image capture unit.

Abstract: Art automated laboratory system comprises a work area comprising a plurality of predefined workstations, wherein each of the plurality of predefined workstations occupies a footprint of a standardized microtiter plate. At least one movement device is configured to move tools above the work area and at least one transport tool is configured to be moved by the movement device in order to relocate laboratory items within the work area. At least one pipetting tool is configured to be moved by the movement device in order to pick up and release pipette tips. A holder for pipette tip carriers comprises at least one carrying apparatus defining a rectangular through-opening, and a support apparatus connected to the carrying apparatus. An electronic control apparatus is connected to the movement device and configured to control movements of the transport tool and at least one pipetting tool by the movement device.

Abstract: Methods are provided for targeting cells for depletion, including without limitation cancer cells, in a regimen comprising contacting the targeted cells with a combination of agents, including (i) an agent that blockades CD47 activity; and (ii) an antibody that specifically binds to EGFR. In some embodiments the cancer cells have a mutated form of one or more of KRAS, NRAS or BRAF. The level of depletion of the targeted cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used.

Abstract: A method for improving the accuracy of a digital medical model of a part of a patient, the method includes obtaining a set of at least 2 medical images of the patient, where an element including a predefined geometry and/or predefined information was attached to the patient during the recording of the medical images; obtaining at least 2 tracking images taken with at least one camera having a known positional relationship relative to the medical imaging device, the tracking images depicting at least part of the element; determining any movement of the element between acquisition of the at least 2 tracking images; and generating the digital medical model from the acquired medical images, wherein the determined movement of the element is used to compensate for any movement of the patient between the acquisition of the medical images.

Abstract: The invention provides genetically modified hematopoietic stem or progenitor cells (HSPCs) and methods of using the HSPCs in stem cell replacement therapy. The HSPCs are genetically modified to express a receptor conferring a selective advantage on the introduced cells relative to endogenous HSPCs or a control HSPCs without the modification. The presence of such a receptor provides resistance to an immunotherapy regime used for eliminating endogenous HSPCs.

Abstract: A mechanism is provided for storing data files in a file system. The file system provides a plurality of reference data files, where each reference data file in the plurality of data files represents a group of similar data files. The mechanism creates a new data file and associated the new data file with one reference data file in the plurality of data files thus defining an associated reference data file of the plurality of reference data files. The mechanism informs the file system about the association of the new data file with the associated reference data file. The mechanism compresses the new data file using the associated reference data file thereby forming a compressed data file. The mechanism stores the compressed data file together with information about the association of the new data file with the associated reference data file.

Abstract: A semiconductor device includes a semiconductor body comprising a first surface and an edge surface, a contact electrode formed on the first surface and comprising an outer edge side, and a passivation layer section conformally covering the outer edge side of the contact electrode. The passivation layer section is a multi-layer stack comprising a first layer, a second layer, and a third layer. Each of the first, second and third layers include outer edge sides facing the edge surface and opposite facing inner edge sides. The outer edge side of the contact electrode is disposed laterally between the inner edge sides and the outer edge sides of each layer.

Abstract: A semiconductor device includes a contact metallization layer arranged on a semiconductor substrate, an inorganic passivation structure arranged on the semiconductor substrate, and an organic passivation layer. The organic passivation layer is located between the contact metallization layer and the inorganic passivation structure, and located vertically closer to the semiconductor substrate than a part of the organic passivation layer located on top of the inorganic passivation structure.

Abstract: Methods are provided herein for determining and administering optimized dosing of therapeutic anti-D47 agents, in a schedule that provides safe escalation of dose while achieving a therapeutic level in a clinically effective period of time. The methods can comprise the steps of clearance, escalation, and maintenance. In one embodiment the dosing regimen administers an initial (i) sub-therapeutic dose of an anti-CD47 agent or (ii) a cytoreductive therapy to achieve a safe level of circulating tumor cells for subsequent treatment (clearance); escalating the dose of an anti-CD47 agent until a therapeutic dose is reached (escalation); and maintaining the therapeutic dose for a period of time sufficient to reduce tumor cells in the bone marrow of the patient (maintenance). In an alternative dosing regimen, a patient determined to have a safe level of circulating tumor cells at presentation is treated by the steps of escalation and maintenance without initial clearance.

Abstract: An embodiment of a semiconductor device includes a semiconductor body having a first main surface. The semiconductor body includes an active device area and an edge termination area at least partly surrounding the active device area. The semiconductor device further includes a contact electrode on the first main surface and electrically connected to the active device area. The semiconductor device further includes a passivation structure on the edge termination area and laterally extending into the active device area. The semiconductor device further includes an encapsulation structure on the passivation structure and covering a first edge of the passivation structure above the contact electrode.