Abstract: The present invention relates to a mesenchymal stem cell having immunomodulatory activity and a preparation method therefor and, more specifically, to: a rapamycin-treated mesenchymal stem cell having immunomodulatory activity, which expresses any one or more cell surface factors selected from the group consisting of CCR1, CCR2, CCR3, CCR4, CCR7, CCR9 and CXCR4; a cell therapy composition comprising the mesenchymal stem cell, for preventing or treating immune disorders; and a preparation method for the mesenchymal stem cell having immunomodulatory activity. The rapamycin-treated mesenchymal stem cell having immunomodulatory activity, according to the present invention, has increased expression of IDO, TGF-? and IL-10 which are factors having immunomodulatory activity, has decreased expression of Phospho-mTOR, Rictor and Ractor which are signal transduction factors of mTOR, and has increased expression, in the cell, of autophagic inducer Beclin1, ATG5, ATG7, LC3I or LCII.

Abstract: A virtual machine system clones a parent virtual machine on a host by creating an open virtualization format (OVF) package of the parent virtual machine, creating a metainfo file of the OVF package, sending the metainfo file to a tracker, and cloning the parent virtual machine to other hosts by accessing the tracker to determine pieces of the OVF packages are located on the host and any of the other hosts, downloading the pieces of the OVF packages to the other hosts, assembling the OVF package on the other hosts, and deploying full clones of the parent virtual machine on the other hosts from the assembled OVF package.

Abstract: An example method is provided to process an input in a virtualized computing environment. The virtualized computing environment may include a physical machine running a host operating system and a virtualization software with one or more virtual machines. The example method may include detecting activation of at least one key input that causes a first message to be generated, the first message associated with the key input, comparing the first message with a set of stored messages, wherein any of the set of stored messages can be properly executed by targets in both the host operating system and the virtual machine but with different responses, and determining, based on the comparing, whether the first message is intended for a target in the host operating system or in the virtual machine.

Abstract: The daurinol compound according to the present invention exhibits excellent therapeutic effects on arthritis and inflammatory bowel diseases by having an excellent activity in inhibiting the generation of IL-17 and TNF-?, which are inflammatory cytokines causing inflammation, and can alleviate transplant rejection by inhibiting the proliferation of alloreactive T cells and increasing regulatory T cells; therefore, the daurinol compound according to the present invention can be used as a pharmaceutical composition capable of treating and preventing immune diseases. In addition, being a natural substance derived from the Mongolian medicinal plant Haplophyllum dauricum or Haplophyllum cappadocicum, the daurinol compound according to the present invention does not cause cytotoxicity and thus may be used as a composition for a functional health food capable of preventing and remedying immune diseases.

Abstract: An example method is provided to process an input in a virtualized computing environment. The virtualized computing environment may include a physical machine running a host operating system and a virtualization software with one or more virtual machines. The example method may include detecting activation of at least one key input that causes a first message to be generated, the first message associated with the key input, comparing the first message with a set of stored messages, wherein any of the set of stored messages can be properly executed by targets in both the host operating system and the virtual machine but with different responses, and determining, based on the comparing, whether the first message is intended for a target in the host operating system or in the virtual machine.

Abstract: Disclosed is a spray layer capable of germ eradication, finger prints prevention, and good touch feeling, comprising ingredients of following weight percentage (wt %): polyurethanes resin 20 wt %˜40 wt %, isocyanate curing agent 3 wt %˜10 wt %, touch feeling agent 6 wt %˜15 wt %, dissipation agent 1 wt %˜2 wt %, drier activation agent 0.1 wt %˜1 wt %, leveling agent 0.5 wt %˜2 wt %, diluting agent 10 wt %˜40 wt %, graffiti barrier agent 5 wt %˜15 wt %, germicide A 0.5 wt %˜1.5 wt %,germicide B 0.2 wt %˜1 wt %. Also disclosed are a method of spraying the spray layer, and an application of the spray layer.

Abstract: The present invention relates to a composition for preventing or treating an autoimmune disease comprising, as an active ingredient, PINK1 protein or polynucleotide encoding the same. The PINK1 protein according to the present invention inhibits the activity of Th17, promotes the activity of a regulatory T cell (Treg), and increases autophagy in Treg cells, thereby controlling excessive immune responses. Therefore, the PINK1 protein can be effectively used as a pharmaceutical composition or an immunosuppressant, which is capable of preventing or treating an autoimmune disease, such as arthritis, and the like, caused by dysregulation of various kinds of immune responses.

Abstract: The present invention relates to a composition comprising GRIM-19 protein as an active ingredient for preventing or treating obesity or lipid-related metabolic diseases. More particularly, the present invention relates to a composition for preventing or treating obesity or lipid-related metabolic diseases wherein the composition comprises GRIM-19 protein as an active ingredient for preventing or treating metabolic diseases caused by immune response disorders or interactions between genetic, metabolic, or environmental complex factors. The GRIM-19 protein according to the present invention exhibits excellent effectiveness not only in reducing lipocytes and total cholesterol content in the body, but also in suppressing the differentiation of cytotoxic Th17 cells that produce and secrete inflammatory cytokines. Also, GRIM-19 has been found to have excellent effectiveness in regulating a STAT3 mediated inflammatory response in an inflammatory environment related to obesity.

Abstract: The present invention relates to a composition for preventing or treating immune diseases through the suppression of B cell activity induced by metformin. More particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by suppression or reduction of B cell activity which is a cause of disease. The present invention can be valuable in the use thereof for various autoimmune diseases as an immunosuppressant which can prevent or treat immune diseases by suppressing or reducing B cell activity and Th17 cell activity, which are causes of disease, or by promoting or increasing regulatory T cell activity.

Abstract: The present invention relates to a composition comprising metformin as an active ingredient for preventing or treating inflammatory bowel disease. The metformin compound or the metformin-etanercept (product name: Enbrel) composite according to the present invention may have excellent effects of maintaining the thickness of the small intestine and length of the large intestine normal, inhibiting or decreasing the activity of IL-17 and TNF-a, and promoting or increasing the activity of IFNr, and therefore can be effectively used as a pharmaceutical composition for preventing or treating autoimmune diseases including inflammatory bowel disease.

Abstract: An apparatus for charging a user customized service includes: an image processor to receive image data of a user captured by an image capturer and to extract specific data from the image data; a user identifier to identify user identification data of the user based on the specific data; a service extractor to extract the user customized service to be offered to the user, based on the user identification data of the user; a service provider to receive information on the user customized service from a service storage unit and to provide the information to the user; and a service charger to calculate a service fee for the user customized service of the service provider by an exposure time ratio of the user customized service exposed to the user.

Abstract: Provided are a method and apparatus for reproducing at least one piece of content received via at least one interface. The method includes classifying the at least one piece of content respectively received via the at least one interface according to a reference attribute, allocating the classified at least one piece of content to a virtual channel, and selecting a channel from among set channels that include the virtual channel and an occupied basic channel.

Abstract: A blade-type fluid transmission device includes a rotor eccentrically located in the room of a stator and the outer periphery of the rotor is tangent to the inner periphery of the room. At least one blade is pivotably connected to stator and movably inserted in at least one slot of the rotor. The distal end of the at least one blade is in contact with the inner periphery of the room so as to form a space for receiving fluid between the outer periphery of the rotor and the inner periphery of the room. The contact between the at least one blade and the inner periphery of the room increases the efficiency for transmitting fluid which enters into the stator from an inlet and leaves from the stator from an outlet.

Abstract: A blade-type fluid transmission device includes a rotor eccentrically located in the room of a stator and the outer periphery of the rotor is tangent to the inner periphery of the room. At least one blade is pivotably connected to stator and movably inserted in at least one slot of the rotor. The distal end of the at least one blade is in contact with the inner periphery of the room so as to form a space for receiving fluid between the outer periphery of the rotor and the inner periphery of the room. The contact between the at least one blade and the inner periphery of the room increases the efficiency for transmitting fluid which enters into the stator from an inlet and leaves from the stator from an outlet.

Abstract: Provided are a method and apparatus for reproducing at least one piece of content received via at least one interface. The method includes classifying the at least one piece of content respectively received via the at least one interface according to a reference attribute, allocating the classified at least one piece of content to a virtual channel, and selecting a channel from among set channels that include the virtual channel and an occupied basic channel.

Abstract: Provided are systems and methods for electronic receipt management using a user terminal which includes an electronic wallet where payment information is stored, an electronic receipt application storing and managing an electronic receipt, an installation number generated to determine what number of application is installed when the electronic receipt application is installed, a dongle including a payment request relay unit requesting an installation number and payment information to the user terminal to transfer received installation number, payment information, and the amount of requested payment to a payment server, a payment unit making a payment using the payment information and the amount of requested payment received from the payment request relay unit and an electronic receipt issuing unit issuing an electronic receipt when the payment unit makes a payment and transferring the issued electronic receipt and the installation number received from the payment request relay unit to an electronic receipt se

Abstract: A blade-type fluid transmission device includes a rotor eccentrically located in the room of a stator and the outer periphery of the rotor is tangent to the inner periphery of the room. At least one blade is pivotably connected to stator and movably inserted in at least one slot of the rotor. The distal end of the at least one blade is in contact with the inner periphery of the room so as to form a space for receiving fluid between the outer periphery of the rotor and the inner periphery of the room. The contact between the at least one blade and the inner periphery of the room increases the efficiency for transmitting fluid which enters into the stator from an inlet and leaves from the stator from an outlet.

Abstract: The present invention provides a tumor cell-soluble TNF family member molecule complex containing a tumor cell and an isolated soluble TNF family member molecule, wherein the soluble TNF family member molecule is bound on a surface of the tumor cell such that it binds to a receptor of the TNF family member expressed on a surface of a cell other than the tumor cell, and stimulates the cell other than the tumor cell via the receptor, and a composition and a tumor vaccine, each containing the complex.

Abstract: A mobile flow rate measuring system and method, which can recognize a flow rate at a site, and acquire and utilize data on water level, flow velocity, and flow rate of a plurality of agricultural waterways, by acquiring water level information and site features stored in a remote server from a tag installed at the site by a mobile apparatus and comparing images continuously acquired from the agricultural waterways through an image photographing camera to calculate the surface velocity of the waterway.

Abstract: The invention provides novel arylbicyclo[3.1.0]hexylamines, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including but not limited to depression and anxiety.