Patents by Inventor Jia-Ning Xiang

Jia-Ning Xiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
    Patent number: 7423169
    Abstract: The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.
    Type: Grant
    Filed: August 21, 2006
    Date of Patent: September 9, 2008
    Assignee: Xenoport, Inc.
    Inventors: Stephen P. Raillard, Cindy X. Zhou, Fenmei Yao, Suresh Kumar Manthati, Jia-Ning Xiang, Mark A. Gallop
  • Levodopa dimethyl-substituted diester prodrugs compositions, and methods of use
    Publication number: 20080214663
    Abstract: Levodopa dimethyl-substituted diester prodrugs pharmaceutical, compositions comprising levodopa dimethyl-substituted diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided.
    Type: Application
    Filed: December 20, 2007
    Publication date: September 4, 2008
    Inventors: Jia-Ning Xiang, Cindy X. Zhou, Fenmei Yao, Mark Q. Nguyen
  • Catechol protected levodopa diester prodrugs, compositions, and methods of use
    Publication number: 20080171789
    Abstract: Catechol protected levodopa diester prodrugs pharmaceutical, compositions comprising catechol protected levodopa diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided.
    Type: Application
    Filed: December 20, 2007
    Publication date: July 17, 2008
    Inventors: Jia-Ning Xiang, Cindy X. Zhou, Fenmei Yao, Mark Q. Nguyen
  • Levodopa prodrugs, and compositions and uses thereof
    Publication number: 20080132570
    Abstract: Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.
    Type: Application
    Filed: January 10, 2008
    Publication date: June 5, 2008
    Applicant: XenoPort, Inc.
    Inventors: Jia-Ning Xiang, Mark A. Gallop, Cindy X. Zhou
  • Peptide deformylase inhibitors
    Patent number: 7375120
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: May 20, 2008
    Assignee: Smithkline Beecham Corporation
    Inventors: Siegfried B. Christensen, IV, Maxwell D. Cummings, Jinhwa Lee, Jia-ning Xiang
  • Levodopa prodrugs, and compositions and uses thereof
    Publication number: 20080103200
    Abstract: Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.
    Type: Application
    Filed: December 11, 2007
    Publication date: May 1, 2008
    Applicant: XenoPort, Inc.
    Inventors: Jia-Ning Xiang, Mark Gallop, Cindy Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth Cundy
  • Levodopa prodrugs, and compositions and uses thereof
    Patent number: 7342131
    Abstract: Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: March 11, 2008
    Assignee: XenoPort, Inc.
    Inventors: Jia-Ning Xiang, Mark A. Gallop, Cindy X. Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth C. Cundy, Nelson L. Jumbe
  • Methods for Synthesis of Acyloxyalkyl Derivatives of GABA Analogs
    Publication number: 20080058546
    Abstract: The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.
    Type: Application
    Filed: November 1, 2007
    Publication date: March 6, 2008
    Inventors: Stephen Raillard, Cindy Zhou, Fenmei Yao, Suresh Manthati, Jia-Ning Xiang, Mark Gallop
  • Acyloxyalkyl carbamate prodrugs of alpha-amino acids, methods of synthesis and use
    Publication number: 20080051458
    Abstract: Acyloxyalkyl carbamate prodrugs of ?-amino acids, pharmaceutical compositions thereof, methods of making acyloxyalkyl carbamate prodrugs of ?-amino acids and methods of using acyloxyalkyl carbamate prodrugs of ?-amino acids, and pharmaceutical compositions thereof to treat a disease are disclosed. Acyloxyalkyl carbamate prodrugs of ?-amino acids suitable for oral administration using sustained release dosage forms are also disclosed.
    Type: Application
    Filed: July 26, 2007
    Publication date: February 28, 2008
    Inventors: Xuedong Dai, Archana Gangakhedkar, Jia-Ning Xiang, Mark Gallop
  • Levodopa prodrugs, and compositions and uses thereof
    Patent number: 7323585
    Abstract: Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: January 29, 2008
    Assignee: XenoPort, Inc.
    Inventors: Jia-Ning Xiang, Mark A. Gallop, Cindy X. Zhou, Mark Nguyen, Xuedong Dai, Jianhua Li, Kenneth C. Cundy
  • Levodopa prodrug mesylate, compositions thereof, and uses thereof
    Publication number: 20070225366
    Abstract: (2R)-2-Phenylcarbonyloxypropyl(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided.
    Type: Application
    Filed: December 4, 2006
    Publication date: September 27, 2007
    Inventors: Jia-Ning Xiang, Xuedong Dai, Cindy Zhou, Jianhua Li, Mark Nguyen
  • Peptide Deformylase Inhibitors
    Publication number: 20070155792
    Abstract: PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: March 7, 2007
    Publication date: July 5, 2007
    Inventors: Kelly Aubart, Jia-Ning Xiang, Siegfried Christensen, Xiangmin Liao, Maxwell Cummings
  • Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
    Patent number: 7232924
    Abstract: The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: June 19, 2007
    Assignee: Xenoport, Inc.
    Inventors: Stephen P. Raillard, Cindy X. Zhou, Fenmei Yao, Suresh Kumar Manthati, Jia-Ning Xiang, Mark A. Gallop
  • Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
    Patent number: 7208611
    Abstract: Platinum containing compounds exhibiting cytostatic activity, methods of synthesizing platinum-containing compounds exhibiting cytostatic activity pharmaceutical compositions comprising platinum containing compounds, and methods of using such compounds and compositions for treating cancer are disclosed.
    Type: Grant
    Filed: February 23, 2006
    Date of Patent: April 24, 2007
    Assignee: XenoPort, Inc.
    Inventors: Qingzhi Gao, Mark A. Gallop, Jia-Ning Xiang
  • Prodrugs of GABA analogs, compositions and uses thereof
    Patent number: 7186855
    Abstract: The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: March 6, 2007
    Assignee: Xenoport, Inc.
    Inventors: Mark A. Gallop, Kenneth C. Cundy, Cindy X. Zhou, Fayang Gregory Qiu, Fenmei Yao, Jia-Ning Xiang, Ian R. Ollman
  • Prodrugs of GABA analogs, compositions and uses thereof
    Publication number: 20070010453
    Abstract: The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.
    Type: Application
    Filed: May 22, 2006
    Publication date: January 11, 2007
    Inventors: Mark Gallop, Kenneth Cundy, Cindy Zhou, Fayang Qiu, Fenmei Yao, Jia-Ning Xiang, Ian Ollmann
  • Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
    Publication number: 20060287250
    Abstract: The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.
    Type: Application
    Filed: August 21, 2006
    Publication date: December 21, 2006
    Inventors: Stephen Raillard, Cindy Zhou, Fenmei Yao, Suresh Manthati, Jia-Ning Xiang, Mark Gallop
  • Peptide deformylase inhibitors
    Publication number: 20060229341
    Abstract: Novel PDF inhibitors and novel methods for their use are provided.
    Type: Application
    Filed: April 16, 2003
    Publication date: October 12, 2006
    Inventors: Siegfried Christensen, Maxwell Cummings, Jinhwa Lee, Jia-ning Xiang
  • Prodrugs of GABA analogs, compositions and uses thereof
    Publication number: 20060229361
    Abstract: The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.
    Type: Application
    Filed: April 6, 2005
    Publication date: October 12, 2006
    Inventors: Mark Gallop, Kenneth Cundy, Cindy Zhou, Fenmei Yao, Jia-Ning Xiang, Ian Ollman, Fayang Qiu
  • Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
    Publication number: 20060205677
    Abstract: Platinum containing compounds exhibiting cytostatic activity, methods of synthesizing platinum-containing compounds exhibiting cytostatic activity pharmaceutical compositions comprising platinum containing compounds, and methods of using such compounds and compositions for treating cancer are disclosed.
    Type: Application
    Filed: February 23, 2006
    Publication date: September 14, 2006
    Inventors: Qingzhi Gao, Mark Gallop, Jia-Ning Xiang