Patents by Inventor Jian Yu

Jian Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recovery and purification of polyhydroxyalkanoates
    Patent number: 7514525
    Abstract: The present invention relates to a method to recover, purify and isolate polyhydroxyalkanoate (PHA) biopolymers from PHA-containing cell mass, which includes: (a) solubilizing the non-PHA cell mass in an acidic solution, leaving a suspension of partially crystallized PHA granules; (b) adjusting the pH of the suspension to 7-11 and separating the PHA solids from the dissolved non-PHA cellular mass; (c) re-suspending the PHA solids in a bleaching solution for decolorization; and (d) drying the resulting PHA solids. About 95% or greater of original PHA in cell mass is recovered, and the purity of PHA solids is about 97% or above. The weight average molecular mass of the purified biopolyesters is about 500 kDa or greater.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: April 7, 2009
    Assignee: University of Hawaii
    Inventor: Jian Yu
  • System for extended high frame rate imaging with limited-diffraction beams
    Publication number: 20090066727
    Abstract: A system for producing a high frame rate image includes transmitting a single weighted spatial frequency signal of energy toward an object to be imaged; weighting multiple receive spatial frequency signals from the object, or by performing a spatial Fourier transform; reconstructing an image data set from the single transmitted spatial frequency signal and the multiple receive spatial frequency signals; and, reconstructing the high frame rate, high resolution and high contrast image from the image data set.
    Type: Application
    Filed: August 29, 2006
    Publication date: March 12, 2009
    Inventors: Jian-yu Lu, Jiqi Cheng
  • Tyrosine phosphorylation sites
    Publication number: 20090053831
    Abstract: The invention discloses 405 novel phosphorylation sites identified in carcinoma and/or leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.
    Type: Application
    Filed: April 30, 2008
    Publication date: February 26, 2009
    Inventors: Peter Hornbeck, Ailan Guo, Ting-Lei Gu, Klarisa Rikova, Albrecht Moritz, Charles Farnsworth, Matthew Stokes, Jian Yu, Erik Spek, Yu Li, Valerie Goss, Francesco Boccalatte
  • Method for focusing by using a pre-flash
    Patent number: 7493035
    Abstract: A method for focusing by using a pre-flash is provided. The method includes the following steps. First, the image sensor captures a first image of the object, wherein the average brightness of the first image is calculated to be Y0. Next, the image sensor captures a second image of the object with the aid of a first pre-flash having a first energy, wherein the average brightness of the second image is calculated to be Y1. Afterwards, the image sensor captures a third image of the object with the aid of a second pre-flash having a second energy, wherein the average brightness of the third image is calculated to be Y2. Then, the distance D to the object is calculated according to the brightness Y0 and the difference ?Y between Y1 and Y2. Finally, the image sensor adjusts the focus according to the distance D.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: February 17, 2009
    Assignee: Compal Electronics, Inc.
    Inventors: Lee-Ren Kuo, Jian-Yu Lin, Feng-Chi Chang
  • Alkylamine as an antimicrobial agent in ophthalmic compositions
    Patent number: 7488706
    Abstract: A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following formula, where R1 is a C13-17 alkyl, and R2 and R3 are each independently H or —CH3, and a non-ionic surfactant. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: February 10, 2009
    Assignee: Advanced Medical Optics, Inc.
    Inventor: Zhi-Jian Yu
  • HIGH FRAME RATE IMAGING SYSTEM
    Publication number: 20090036772
    Abstract: A system for producing an image using an imaging system includes a) transmitting at least one signal of energy toward an object to be imaged by using two transmitters having the same output amplitude but of an opposite sign, or by using one transmitter to perform the task; b) exciting at least one transducer element to produce limited-diffraction array beams or their square-wave approximations with two levels of quantitations for both sine and cosine functions, c) weighting the received signals spatially with limited-diffraction array beams, their square-wave approximations, or spatial Fourier transform, and d) digitizing and then transferring received signals through high-speed optical fibers to a system for image reconstructions.
    Type: Application
    Filed: January 26, 2007
    Publication date: February 5, 2009
    Applicant: THE UNIVERSITY OF TOLEDO
    Inventor: Jian-Yu Lu
  • POLYQUATERNIUM-1 SYNTHESIS METHODS
    Publication number: 20080262194
    Abstract: The present embodiments relate to a novel method of making quaternary ammonium polymers comprising the steps of: a) mixing 1,4-bis-dimethylamino-2-butene, triethanolamine, water and an acid; and b) introducing a 1,4-dihalo-2-butene to the mixture so as to initiate a reaction resulting in the quaternary ammonium polymer.
    Type: Application
    Filed: April 17, 2007
    Publication date: October 23, 2008
    Applicant: Advanced Medical Optics, Inc.
    Inventor: Zhi Jian Yu
  • Apparatus for oral examination
    Publication number: 20080242941
    Abstract: The present invention relates to an accessory apparatus for use with conventional tongue depressors. The apparatus comprises a platform, a lens/guard piece wherein said lens/guard has a diameter larger than an average adult's open mouth, and a hinge unit for attachment of said lens/guard to said platform. The apparatus may further comprise a light source and a USB camera.
    Type: Application
    Filed: March 30, 2007
    Publication date: October 2, 2008
    Inventors: John Jungyoon Kim, James Jian Yu Chang
  • RECOVERY AND PURIFICATION OF POLYHYDROXYALKANOATES
    Publication number: 20080220505
    Abstract: The present invention relates to a method to recover, purify and isolate polyhydroxyalkanoate (PHA) biopolymers from PHA-containing cell mass, which includes: (a) solubilizing the non-PHA cell mass in an acidic solution, leaving a suspension of partially crystallized PHA granules; (b) adjusting the pH of the suspension to 7-11 and separating the PHA solids from the dissolved non-PHA cellular mass; (c) re-suspending the PHA solids in a bleaching solution for decolorization; and (d) drying the resulting PHA solids. About 95% or greater of original PHA in cell mass is recovered, and the purity of PHA solids is about 97% or above. The weight average molecular mass of the purified biopolyesters is about 500 kDa or greater.
    Type: Application
    Filed: March 9, 2007
    Publication date: September 11, 2008
    Inventor: Jian Yu
  • ALKYLAMINE AS AN ANTIMICROBIAL AGENT IN OPHTHALMIC COMPOSITIONS
    Publication number: 20080125494
    Abstract: A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following formula, where R1 is a C13-17 alkylamine, and R2 and R3 are each independently H or —CH3, and a non-ionic surfactant. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.
    Type: Application
    Filed: September 25, 2006
    Publication date: May 29, 2008
    Applicant: Advanced Medical Optics, Inc.
    Inventor: Zhi-Jian Yu
  • One-Transistor Random Access Memory Technology Compatible with Metal Gate Process
    Publication number: 20080073688
    Abstract: One-transistor RAM technology compatible with a metal gate process fabricates a metal gate electrode formed of the same metal material as a top electrode of a MIM capacitor embedded isolation structure. A gate dielectric layer is formed of the same high-k dielectric material as a capacitor dielectric of the MIM capacitor embedded isolation structure.
    Type: Application
    Filed: August 9, 2007
    Publication date: March 27, 2008
    Inventors: Kuo-Chi Tu, Kuo-Chyuan Tzeng, Chung-Yi Chen, Jian-Yu Shen, Chun-Yao Chen, Hsiang-Fan Lee
  • UV disinfection systems with tangential inlets and methods thereof
    Publication number: 20070045197
    Abstract: A disinfection system and method includes a reactor with a chamber and at least one radiation source. The chamber in the reactor has at least one inlet that is oriented to generate a vortex motion for a fluid introduced to the chamber. The radiation source is positioned to be offset from an axis which extends along a center of the chamber of the reactor. The radiation source at least partially directs radiation towards a circulating flow of the fluid in the chamber from the vortex motion in at least a gap between a wall of the chamber of the reactor and the at least one radiation source.
    Type: Application
    Filed: June 30, 2006
    Publication date: March 1, 2007
    Applicant: Rochester Institute of Technology
    Inventors: Ali Ogut, Jian Yu
  • Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
    Publication number: 20070036829
    Abstract: An ophthalmic composition is self-emulsifying. The composition includes oil globules having an average size of less than 1 micron dispersed in an aqueous phase. These globules include a surfactant component with one or two surfactants and a polar oil component. The surfactant component and the oil component are selected to self-emulsify when mixed without mechanical homogenization. The composition also includes a disinfectant suitable for ophthalmic use, and can optionally include a therapeutic agent suitable for ophthalmic treatment.
    Type: Application
    Filed: May 3, 2006
    Publication date: February 15, 2007
    Inventors: Zhi-Jian Yu, Stanley Huth
  • Microwave transmitter and the method for increasing envelope bandwidth
    Publication number: 20070018718
    Abstract: The microwave transmitter of the present invention can perform two-terminal dynamic modulation with respect to the voltage supply terminal and the RF input terminal of a RF power amplifier. The microwave transmitter of the present invention comprises a first modulator and a second modulator. The first modulator uses the baseband digital delta-sigma modulation technique to process the envelope signal and outputs this signal to the voltage supply terminal of the RF power amplifier as a supply voltage. The second modulator uses the baseband digital pre-distortion technique to process the IQ-modulated carrier and outputs this signal to the RF input terminal of the RF power amplifier as a RF input signal. Thereby, the RF power amplifier can highly efficiently reconstruct the power-amplified RF modulated carrier without distortion at the RF output terminal.
    Type: Application
    Filed: June 19, 2006
    Publication date: January 25, 2007
    Applicants: National Sun Yat-sen University, Industrial Technology Research Institute
    Inventors: Tzyy-Sheng Horng, Yuan Chen, Je-Kuan Jau, Jian-Yu Li, Chang-Ming Lai
  • Energy efficient, UV water disinfection systems and methods thereof
    Publication number: 20070007217
    Abstract: A system and a method for disinfecting a fluid includes a vessel with at least one passage having at least an inlet and an outlet and one or more radiation sources. The one or more radiation sources are positioned about at least a portion of a perimeter of the passage in the vessel to direct radiation into a fluid in the passage of the vessel to at least partially disinfect the fluid.
    Type: Application
    Filed: June 29, 2006
    Publication date: January 11, 2007
    Applicant: Rochester Institute of Technology
    Inventors: Ali Ogut, Jian Yu, Wei Yang
  • Alkylamine as an antimicrobial agent in ophthalmic compositions
    Patent number: 7157412
    Abstract: A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following formula, where R1 is a C13-17 alkyl, and R2 and R3 are each independently H or —CH3, and a non-ionic surfactant. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: January 2, 2007
    Assignee: Advanced Medical Optics, Inc.
    Inventor: Zhi-Jian Yu
  • Production of biodegradable thermoplastic materials from organic wastes
    Patent number: 7141400
    Abstract: A system and method for converting organic wastes to biodegradable thermoplastic materials including polyhydroxyalkanoates is disclosed, which method includes treating the organic wastes with an acidogenic microbial population to form fermentative organic acids, and polymerization of the organic acids by PHA-producing microbial species to form PHAs. The system includes a first compartment for acidogenesis of organic wastes without oxygen, and a second compartment, for polymer synthesis by enriched cultures of species with oxygen such as R. eutropha, P. oleovorans, or mixtures thereof. The compartments are integrated with barriers that permit mass transfer of organic acids while maintaining different culture conditions in the compartments.
    Type: Grant
    Filed: January 15, 2003
    Date of Patent: November 28, 2006
    Assignee: University of Hawaii
    Inventor: Jian Yu
  • Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye
    Publication number: 20060251685
    Abstract: An ophthalmic composition includes oil globules dispersed in an aqueous phase. The globules include a surfactant component, a polar oil component that includes an Omega-3 fatty acid and a viscosity modifying agent. The surfactant to oil ratio produces an average size of globules of about 0.1 microns or less. The viscosity is at least as viscous as 0.25% 800K sodium hyaluronate. The composition can be used for treatment of dry eye. The compositions are stable and can have anti-microbial activity sufficient for use as contact lens disinfecting solutions.
    Type: Application
    Filed: May 3, 2006
    Publication date: November 9, 2006
    Inventors: Zhi-Jian Yu, Lauren Crawford
  • Borate-polyol mixtures as a buffering system
    Publication number: 20060229219
    Abstract: A buffering system having a pKa which may be selected based on the environment in which the solution is designed to be used. Solutions containing the buffering system according to the present invention include borate-polyol complexes as the primary buffering agents, and may include one or more of the following: an aqueous liquid medium; an antimicrobial component; a surfactant component; a viscosity-inducing component; and/or a tonicity component. The borate-polyol buffering system may be formulated to have a lower pKa than traditional systems.
    Type: Application
    Filed: April 11, 2005
    Publication date: October 12, 2006
    Inventors: Zhi-Jian Yu, Diane Croner
  • METHOD FOR FOCUSING BY USING A PRE-FLASH
    Publication number: 20060216012
    Abstract: A method for focusing by using a pre-flash is provided. The method includes the following steps. First, the image sensor captures a first image of the object, wherein the average brightness of the first image is calculated to be Y0. Next, the image sensor captures a second image of the object with the aid of a first pre-flash having a first energy, wherein the average brightness of the second image is calculated to be Y1. Afterwards, the image sensor captures a third image of the object with the aid of a second pre-flash having a second energy, wherein the average brightness of the third image is calculated to be Y2. Then, the distance D to the object is calculated according to the brightness Y0 and the difference ?Y between Y1 and Y2. Finally, the image sensor adjusts the focus according to the distance D.
    Type: Application
    Filed: October 28, 2005
    Publication date: September 28, 2006
    Inventors: Lee-Ren Kuo, Jian-Yu Lin, Feng-Chi Chang