Abstract: An implantable cardiac device is provided. The implantable cardiac device includes a sensing unit adapted to measure an intrathoracic or intracardiac impedance, pressure, and/or accelerometry input stream, which includes a patient's respiratory waveforms. Furthermore, the implantable cardiac device includes a quantizer-unit adapted to sample the input stream with an initial sampling frequency Fs, providing input samples of the input stream. The implantable cardiac device further includes a filter bank 50 suited to perform a streaming Wavelet transformation on the input samples on a sample-by-sample basis, using the initial sampling frequency Fs provided by the quantizer-unit, wherein the streaming Wavelet transformation is adapted to perform a source separation, extracting, and separating the respiratory waveforms of the input stream.

Abstract: Embodiments of the invention relate generally to graphene fibers and, more particularly, to graphene fibers comprising intercalated large-sized graphene oxide (LGGO)/graphene sheets and small-sized graphene oxide (SMGO)/graphene sheets having high thermal and electrical conductivities and high mechanical strength. In one embodiment, the invention provides a graphene fiber comprising: a plurality of intercalated graphene sheets including: a plurality of large-sized graphene sheets; and a plurality of small-sized graphene sheets, wherein at least one of the plurality of small-sized graphene sheets is disposed between at least two of the plurality of large-sized graphene sheets.

Abstract: The present disclosure describes techniques for converting and storing data in a unified format. One example method includes converting original data to a first data having a predetermined format; generating first metadata and a key value corresponding to the first data during the conversion of the original data; determining whether second metadata corresponding to the key value exists in a cache; determining whether the second metadata are different from the first metadata; in response to determining that the second metadata does not exist in the cache or to determining that the second metadata are different from the first metadata, storing the first data, the first metadata, and the key value to the cache; determining that a predetermined condition is satisfied; and in response determining that the predetermined condition is satisfied, storing the first data, the first metadata, and the key value to a non-relational database.

Abstract: A UV exposure dosimetry system includes at least one UV sensor that measures the UV irradiance intensity. The system can generate extrapolated UV intensity data based on measured UV intensity data to correct unreliable UV measurement due to inconsistent irradiation of UV light. The system integrates the extrapolated UV intensity data over time to calculate real-time UV dosage and vitamin D production by taking into account factors including UV sensor location, body surface area, clothing coverage, and sunscreen usage. Based on the measurement, the system can predict the time remaining to skin burn and the time remaining to reach daily goal of vitamin D production. The system is also adapted to measure sun exposure time based on the corrected UV intensity over a period of time. The UV dosimetry system supports multi-user control through an advanced and user friendly input and output interface.

Abstract: A UV exposure dosimetry system includes at least one UV sensor that accurately measures the UV irradiance intensity. The system can generate extrapolated UV intensity data based on measured UV intensity data to correct unreliable UV measurement due to inconsistent irradiation of UV light. The UV dosimetry system integrates the extrapolated UV intensity data over time to calculate the real-time UV dosage and the vitamin D production by taking into account factors comprising UV sensor location, body surface area, clothing coverage, and sunscreen usage. Based on the measurement, the system can predict the time remaining to skin burn and the time remaining to reach daily goal of vitamin D production. The UV dosimetry system supports multi-user control through an advanced and user friendly input and output interface.

Abstract: A spinal cord stimulation device having a stimulation unit for generation and delivery of stimulation pulses, a control unit for controlling the stimulation unit with respect to stimulation intensity and an autonomic nervous system (“ANS”) sensing unit that is configured to generate ANS indicating signals that represent an increased sympathetic tone or an increased parasympathetic tone, respectively. The control unit is configured to control the intensity of respective stimulation pulses depending on a respective ANS indicating signal as generated by said ANS sensing unit.

Abstract: An implantable pulse generator system includes a stimulation unit delivering vagal nerve stimulation pulses, an activity sensor determining an exertion level of the user and generating a signal representing metabolic demand, an autonomic tone sensor determining an autonomic status of the user and generating a signal representing autonomic status, and a control unit in communication with the foregoing components, and which is adapted to control the stimulation unit depending on both the signal representing metabolic demand and the signal representing autonomic status.

Abstract: A UV exposure dosimetry system includes at least one UV sensor that accurately measures the UV irradiance intensity. The UV dosimetry system integrates the measured UV irradiance intensity over time to calculate the real-time UV dosage and the vitamin D production by taking into account factors comprising UV sensor location, body surface area, clothing coverage, and sunscreen usage. Based on the measurement, the system can predict the time remaining to skin burn and the time remaining to reach daily goal of vitamin D production. The system can also estimate UV intensity for a time in the future at a geographic location based on the forecast UV index data, and predict UV dose and vitamin D generation for the user corresponding to user defined scenarios. The UV dosimetry system supports multi-user control through an advanced and user friendly input and output interface.

Abstract: An implantable pulse generator system includes a nerve stimulation unit providing vagal nerve stimulation (VNS) pulses; an autonomic tone sensor which determines the patient's autonomic status; and a control unit connected to the nerve stimulation unit and the autonomic tone sensor. The control unit controls the nerve stimulation unit to generate VNS with varying intensity, depending on the autonomic status (which is evaluated in a moving window). The control unit gradually increases VNS intensity when the autonomic status indicates a shift toward more sympathetic dominance, and it gradually decreases VNS intensity when the autonomic status indicates a shift toward more parasympathetic dominance, wherein the gradual increase and the gradual decrease of the VNS intensity follow two different paths.

Abstract: Disclosed is a load lock chamber which includes a chamber body including: at least one pair of cavities, defined in a layer structure of the chamber body to carry one or more wafer substrates; at least one internal conduit, defined between and coupled with the paired cavities, such that the paired cavities are communicated with each other and capable of conducting gas refilling and exhaustion; and a plurality of wafer supports for carrying the wafer substrates, the plurality of wafer supports being securely received in the paired cavities and able to calibrate with a machine arm frontend finger, wherein the wafer support includes grooves defined thereon for calibrating the machine arm frontend finger.

Abstract: A UV dosimetry system comprises a wearable unit and a mobile computing device. The wearable unit measures the UV irradiance intensity and wirelessly communicates with the mobile computing device. The UV dosimetry system supports multi-user control and can link one mobile computing device with multiple wearable units. The UV dosimetry system processes the measured UV irradiance intensity to calculate the UV index (UVI) and the sensor site specific UV dose. It can also calculate the total absorbed UV dose and vitamin D production by taking into account user specific factors. The UVI data measured by a plurality of UV meters such as the disclosed UV dosimetry system are crowd sourced to a remote server together with the location and time data of the measurement. The remote server excludes invalid UVI measurement and generates UVI maps showing time-varying distribution of UVI data at different locations.

Abstract: A nerve cuff stimulation electrode for cervical VNS is provided and configured to be arranged so as to at least partially surround or enclose one of the vagus nerves. The cuff stimulation electrode has at least two contacts configured to deliver electric stimulation pulses to a vagus nerve. The cuff stimulation electrode further has or may be attached or connected to a tilt sensor, a kinematic sensor, and/or a pulsation sensor configured to generate a signal representative of arterial and venous pressures. The implantable tilt sensor is configured to output a posture signal indicating a patient's posture, thus allowing discrimination between supine and semi-recumbent or erect postures.

Abstract: A spinal cord stimulation device having a stimulation unit for generation and delivery of stimulation pulses, a control unit for controlling the stimulation unit with respect to stimulation intensity and an autonomic nervous system (“ANS”) sensing unit that is configured to generate ANS indicating signals that represent an increased sympathetic tone or an increased parasympathetic tone, respectively. The control unit is configured to control the intensity of respective stimulation pulses depending on a respective ANS indicating signal as generated by said ANS sensing unit.

Abstract: A UV exposure dosimetry system includes at least one UV sensor that accurately measures the UV irradiance intensity. The system can generate extrapolated UV intensity data based on measured UV intensity data to correct unreliable UV measurement due to inconsistent irradiation of UV light. The UV dosimetry system integrates the extrapolated UV intensity data over time to calculate the real-time UV dosage and the vitamin D production by taking into account factors comprising UV sensor location, body surface area, clothing coverage, and sunscreen usage. Based on the measurement, the system can predict the time remaining to skin burn and the time remaining to reach daily goal of vitamin D production. The UV dosimetry system supports multi-user control through an advanced and user friendly input and output interface.

Abstract: A UV exposure dosimetry system includes at least one UV sensor that accurately measures the UV irradiance intensity. The UV dosimetry system integrates the measured UV irradiance intensity over time to calculate the real-time UV dosage and the vitamin D production by taking into account factors comprising UV sensor location, body surface area, clothing coverage, and sunscreen usage. Based on the measurement, the system can predict the time remaining to skin burn and the time remaining to reach daily goal of vitamin D production. The system can also provide feedback to the user of the device based on a composite metric assessing the degree of balance between the risk of UV exposure and the benefit of UV exposure. The UV dosimetry system supports multi-user control through an advanced and user friendly input and output interface.

Abstract: A device that monitors and evaluates electrogram signals representing electric activities of a heart chamber, and includes a signal input connected to a mapping catheter, and a signal processing and evaluation unit. The mapping catheter includes one or more electrode poles that pick up electric potentials and generate electrogram signals therefrom.

Abstract: A spinal cord stimulation device having a stimulation unit for generation and delivery of stimulation pulses, a control unit for controlling the stimulation unit with respect to stimulation intensity and an autonomic nervous system (“ANS”) sensing unit that is configured to generate ANS indicating signals that represent an increased sympathetic tone or an increased parasympathetic tone, respectively. The control unit is configured to control the intensity of respective stimulation pulses depending on a respective ANS indicating signal as generated by said ANS sensing unit.

Abstract: An implantable medical device includes an actuator and/or sensor portion to be fixed to bodily tissue by means of a fixation mechanism, to act on the tissue and/or to detect a signal from the tissue, wherein at least one detector element, preferably a plurality of detector elements, adapted for detecting the close proximity of bodily tissue, is arranged on the actuator and/or sensor portion of the device, and an output of the or each detector element being connected or connectable to a detection signal evaluation unit for deriving a fixation state verification from detection signals provided by the or each detector element.

Abstract: Supercapacitors have composite electrodes that include a porous carbonaceous material such as graphene onto which a metal oxide pseudocapacitor material is deposited in the form of nano-scale particles or a nano-scale film. The composite electrodes exhibit excellent specific capacitance, even at high scan rates.