Patents by Inventor John C. Sih

John C. Sih has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 13,14-Dihydro-inter-ox a-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.sub.1 compounds
    Patent number: 4292439
    Abstract: The present invention provides novel 13,14-dihydro-inter-oxa-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-o xo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 29, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-9-deoxy-9-methylene-19-oxo-PGF.sub.2 compounds
    Patent number: 4292438
    Abstract: The present invention provides novel 13,14-didehydro-9-deoxy-9-methylene-19-oxo-PGF.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 29, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-11-deoxy-19-oxo-PGF.sub.2 compounds
    Patent number: 4292442
    Abstract: The present invention provides novel 13,14-didehydro-11-deoxy-19-oxo-PGF.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 29, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-11-deo xy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.sub.2 compounds
    Patent number: 4292441
    Abstract: The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.s ub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 29, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE.sub.2 compounds
    Patent number: 4292443
    Abstract: The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 29, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-9-deoxy-9-methylene-19-oxo-PGF.sub.1 compounds
    Patent number: 4292440
    Abstract: The present invention provides novel 13,14-didehydro-9-deoxy-9-methylene-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 29, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Dihydro-inter-oxa-11-deoxy-9-deoxy-9-methylene-19-oxo-PFG.sub.1 compounds
    Patent number: 4291173
    Abstract: The present invention provides novel 13,14-dihydro-inter-oxa-11-deoxy-9-deoxy-9-methylene-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 22, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Dihydro-inter-oxa-11-deoxy-19-oxo-PGE.sub.1 compounds
    Patent number: 4291172
    Abstract: The present invention provides novel 13,14-dihydro-inter-oxa-11-deoxy-19-oxo-PGE.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 22, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Dihydro-11-deoxy-19-oxo-PGF.sub.1 compounds
    Patent number: 4289901
    Abstract: The present invention provides novel 13,14-dihydro-11-deoxy-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-11-deoxy-19-oxo-PGE.sub.2 compounds
    Patent number: 4289900
    Abstract: The present invention provides novel 13,14-didehydro-11-deoxy-19-oxo-PGE.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-19-oxo-PGE.sub.1 analogs
    Patent number: 4289899
    Abstract: The present invention provides novel 13,14-didehydro-19-oxo-PGE.sub.1 analogs, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 2,5-Inter-O-phenylene-3,4-dinor-PGF.sub.2 compounds
    Patent number: 4289893
    Abstract: The present invention provides 2,5-inter-o-phenylene-3,4-dinor-PGF.sub.2 compounds. These compounds are intermediates for preparing 2,5-inter-o-phenylene-3,4-dinor-prostacyclin analogs, which are useful for pharmacological purposes, e.g., as antithrombotic agents.
    Type: Grant
    Filed: July 3, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventors: Udo F. Axen, John C. Sih
  • 13,14-Dihydro-11-deoxy-19-oxo-PGE.sub.1 compounds
    Patent number: 4289902
    Abstract: The present invention provides novel 13,14-dihydro-11-deoxy-19-oxo-PGE.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-19-oxo-PGE.sub.2 compounds
    Patent number: 4289898
    Abstract: The present invention provides novel 13,14-didehydro-19-oxo-PGE.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-6a-carba-PGI.sub.2 sulfonylamides
    Patent number: 4289904
    Abstract: The present invention provides novel 19-hydroxy-6a-carba-PGI.sub.2 sulfonylamides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: September 15, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF.sub.2 compounds
    Patent number: 4288616
    Abstract: The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 8, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Oxo-PGF.sub.2 analogs
    Patent number: 4288618
    Abstract: The present invention provides novel 19-oxo-PGF.sub.2 analogs, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 8, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Esters of prostacyclin-type compounds
    Patent number: 4288606
    Abstract: Acyl-substituted phenyl esters of prostacyclin-type compounds, for example the 4-acetylphenyl ester of prostacyclin (PGI.sub.2) illustrated by the formula ##STR1## and including esters of the isomeric 6-hydroxy-PGI.sub.2 and 6-keto-PGF.sub.1.alpha. compounds, said esters having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.
    Type: Grant
    Filed: February 15, 1980
    Date of Patent: September 8, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 19-Hydroxy-19-methyl-6,7-didehydro-PGI.sub.1 compounds
    Patent number: 4288371
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-6,7-didehydro-PGI.sub.1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: September 8, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • 13,14-Didehydro-19-oxo-PGF.sub.1 compounds
    Patent number: 4288617
    Abstract: The present invention provides novel 13,14-didehydro-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: September 8, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih