Abstract: Disclosed herein is a multiplex microarray having serially attached non-functionalized biomolecules attached to a polymer coating covering each electrode of an array of electrodes for assays and a method of making the multiplex microarray. The method comprises serially blocking the electrodes of the microarray with a blocking protein, electropolymerizing pyrrole or a functionalized pyrrole on the electrodes where the biomolecule is not present during polymerization, exposing the microarray to a biomolecular solution containing a non-functionalized biomolecule for attachment to the polymer coating, and then repeating the steps to form the multiplex microarray.

Abstract: Functionalized aryldiazonium salts and films formed by electrografting of functionalized aryldiazonium salts are provided. Methods for purifying functionalized aryldiazonium salts and for coating solid support systems with functionalized aryldiazonium salts are also provided. These coated solid support systems can be used, for example, in methods of oligonucleotide synthesis.

Abstract: Provided herein are methods and compositions for oligonucleotide synthesis utilizing universal linker phosphoramidites. Methods and reagents are described with DNA synthesis using controlled pore glass (CPG) solid supports, and on platinum coated electrodes for electrochemical DNA synthesis. The universal linkers can be used as spacers in single-column PCR primer synthesis to generate 2 strands with free 3?-hydroxy termini after cleavage. The methods and compositions utilize a solid support system for synthesis of oligonucleotides, wherein the support has platinum electrodes and a universal linker, optionally wherein the platinum electrode is coated with an amine. The methods and compositions further describe use of universal linker phosphoramidites and the platinum electrode is coated with a monosaccharide, or a disaccharide.

Abstract: An apparatus includes a semiconductor-based substrate with a functional structure that is formed in or on the semiconductor-based substrate. The apparatus includes a frame structure surrounding the functional structure and includes a coating that covers the functional structure and is delimited by the frame structure.

Abstract: A method to store the shapes of an electrical circuit design in a hierarchical set of arrays that inverts the layout size order by area includes defining a plurality of storage levels. Each level corresponds to a two-dimensional projection of the three-dimensional volume of the circuit layout. Accordingly, each level subsumes the entire physical space of the circuit layout. Each level may include a respective grid of slots. The slots may be rectangular. Each slot within any single level may be the same size and dimensions as every other slot in this level. Shapes are added to this storage technique based upon size, not based upon physical layer. Each slot can contain shapes from any physical layer as long as that shape fits entirely within the slot.

Abstract: A method of processing a semiconductor wafer includes: forming a first metal layer or metal layer stack on a backside of the semiconductor wafer; forming a plating preventative layer on the first metal layer or metal layer stack, the plating preventative layer being formed at least over a kerf region of the semiconductor wafer and such that part of the first metal layer or metal layer stack is uncovered by the plating preventative layer, wherein the kerf region defines an area for dividing the semiconductor wafer along the kerf region into individual semiconductor dies; and plating a second metal layer or metal layer stack on the part of the first metal layer or metal layer stack uncovered by the plating preventative layer, wherein the plating preventative layer prevents plating of the second metal layer or metal layer stack over the kerf region.

Abstract: A computer-implemented method for securing a user device is disclosed. A signed device authentication key is requested and received from a user application executing on the user device. The signed device authentication key is obtained via a software module installed on the user device and associated with a secure data processing provider. A device setup request is transmitted from the user device to the secure data processing system using the signed device authentication key. The device setup request comprises the signed device authentication key. The authenticity of the device setup request is verified at the secure data processing system based on the signed device authentication key.

Abstract: A method of processing a semiconductor wafer includes: forming a first metal layer or metal layer stack on a backside of the semiconductor wafer; forming a plating preventative layer on the first metal layer or metal layer stack, the plating preventative layer being formed at least over a kerf region of the semiconductor wafer and such that part of the first metal layer or metal layer stack is uncovered by the plating preventative layer, wherein the kerf region defines an area for dividing the semiconductor wafer along the kerf region into individual semiconductor dies; and plating a second metal layer or metal layer stack on the part of the first metal layer or metal layer stack uncovered by the plating preventative layer, wherein the plating preventative layer prevents plating of the second metal layer or metal layer stack over the kerf region.

Abstract: A method to store the shapes of an electrical circuit design in a hierarchical set of arrays that inverts the layout size order by area includes defining a plurality of storage levels. Each level corresponds to a two-dimensional projection of the three-dimensional volume of the circuit layout. Accordingly, each level subsumes the entire physical space of the circuit layout. Each level may include a respective grid of slots. The slots may be rectangular. Each slot within any single level may be the same size and dimensions as every other slot in this level. Shapes are added to this storage technique based upon size, not based upon physical layer. Each slot can contain shapes from any physical layer as long as that shape fits entirely within the slot.

Abstract: An apparatus includes a semiconductor-based substrate with a functional structure that is formed in or on the semiconductor-based substrate. The apparatus includes a frame structure surrounding the functional structure and includes a coating that covers the functional structure and is delimited by the frame structure.

Abstract: An apparatus includes a semiconductor-based substrate with a functional structure that is formed in or on the semiconductor-based substrate. The apparatus includes a frame structure surrounding the functional structure and includes a coating that covers the functional structure and is delimited by the frame structure.

Abstract: Transport vessel filling systems, methods and apparatus are described. Some embodiments include liquid fill nozzle assemblies. Some liquid fill nozzle assemblies are in fluid communication with a sprayfill standpipe. Some liquid fill nozzle assemblies include a plurality of liquid fill nozzle assemblies configured to extend to on one or both lateral sides of a vessel.

Abstract: A computer-implemented method for securing a user device is disclosed. A signed device authentication key is requested and received from a user application executing on the user device. The signed device authentication key is obtained via a software module installed on the user device and associated with a secure data processing provider. A device setup request is transmitted from the user device to the secure data processing system using the signed device authentication key. The device setup request comprises the signed device authentication key. The authenticity of the device setup request is verified at the secure data processing system based on the signed device authentication key.

Abstract: A vehicle seat restraint system includes a control system and a second-row restraint system. The control system receives a first-row seat value and a second-row seat value from seat sensors. The control system generates relative position data for a first-row seat and a second-row seat based upon the first-row seat value and the second-row seat value. The control system selects a load limiter setting value using a multidimensional load limiter model based upon body impact values as a function of load limiter setting values and the relative position data, a selected load limiter setting value outside a value avoidance zone for the body impact values. The second-row restraint system is configured by the control system with the selected load limiter setting value. The control system may also determine an occupant weight value and select the load limiter setting value using the occupant weight value.

Abstract: Disclosed herein is a multiplex microarray having serially attached non-functionalized biomolecules attached to a polymer coating covering each electrode of an array of electrodes for assays and a method of making the multiplex microarray. The method comprises serially blocking the electrodes of the microarray with a blocking protein, electropolymerizing pyrrole or a functionalized pyrrole on the electrodes where the biomolecule is not present during polymerization, exposing the microarray to a biomolecular solution containing a non-functionalized biomolecule for attachment to the polymer coating, and then repeating the steps to form the multiplex microarray.

Abstract: An apparatus includes a semiconductor-based substrate with a functional structure that is formed in or on the semiconductor-based substrate. The apparatus includes a frame structure surrounding the functional structure and includes a coating that covers the functional structure and is delimited by the frame structure.

Abstract: A method of characterizing the structure of a void sensitized liquid energetic material, which method comprises defining the material in terms distribution function, the distribution function representing the fraction of liquid energetic material that occurs at a given point within the void sensitized liquid energetic material.

Abstract: An explosive composition comprising a liquid energetic material and sensitizing voids, wherein the sensitizing voids are present in the liquid energetic material with a non-random distribution, wherein the liquid energetic material comprises (a) regions in which the sensitizing voids are sufficiently concentrated to render those regions detonable and (b) regions in which the sensitizing voids are not so concentrated and wherein the explosive composition does not contain ammonium nitrate prill.