Abstract: Systems and methods for quality of experience measurement and wireless network recommendation and/or switching are disclosed. In some embodiments, a method comprises connecting to a cellular data network, measuring a signal strength value of a Wi-Fi data network within range of the digital device, calculating an overall Wi-Fi score based on the measured signal strength value of the Wi-Fi data network, measuring a signal strength value of the cellular data network, calculating an available bandwidth of the cellular data network, calculating an overall cellular data network score based on the measured signal strength value of the cellular data network and the calculated available bandwidth of the cellular data network, comparing the overall Wi-Fi score and the overall cellular data network score, and switching from the cellular data network to the Wi-Fi data network based on the comparison of the first bandwidth score to the bandwidth threshold value.

Abstract: A method for delivering therapeutic radiation to a target includes positioning a multi-aperture collimator on the skin within a trajectory of orthovoltage x-rays directed at the target, thus generating an array of minibeams, each of width between 0.1 mm to 0.6 mm. The skin is irradiated with the array. An effective beam of therapeutic radiation, which may be a solid beam, is delivered to the target at a predetermined tissue depth by merging adjacent orthovoltage x-ray minibeams sufficiently to form the effective beam. The effective beam may be formed proximal to the target. The depth at which the effective, preferably, solid, beam is formed is controlled by varying one or more of the spacing of the minibeams in the array, the minibeam width, the distance from the x-ray source to the collimator, and the x-ray source spot size. Planar minibeams can be arc-scanned while continuously modulating beam shape and intensity.

Abstract: A control system for providing a closed loop, real time control of a charged particle pencil beam is disclosed. The system includes a first detector apparatus, a second detector apparatus, a first orthogonal magnetic deflector apparatus, a second orthogonal magnetic deflector apparatus, and a controller. The controller compares the measured position and beam angle of the beam with a model position and beam angle of a model beam to determine an offset error and a beam angle error. The first orthogonal magnetic deflector apparatus includes a pair of electromagnets to correct a first component of the offset and beam angle errors. The second orthogonal magnetic deflector apparatus includes a pair of electromagnets to correct a second component of the offset and beam angle errors. The beam can be iteratively adjusted during patient therapy or short pauses in patient therapy.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: A method for delivering therapeutic radiation to a target includes positioning a multi-aperture collimator on the skin within a trajectory of orthovoltage x-rays directed at the target, thus generating an array of minibeams, each of width between 0.1 mm to 0.6 mm. The skin is irradiated with the array. An effective beam of therapeutic radiation, which may be a solid beam, is delivered to the target at a predetermined tissue depth by merging adjacent orthovoltage x-ray minibeams sufficiently to form the effective beam. The effective beam may be formed proximal to the target. The depth at which the effective, preferably, solid, beam is formed is controlled by varying one or more of the spacing of the minibeams in the array, the minibeam width, the distance from the x-ray source to the collimator, and the x-ray source spot size. Planar minibeams can be arc-scanned while continuously modulating beam shape and intensity.

Abstract: This disclosure includes devices, systems, and methods for identifying and tracking products to be obtained and/or tasks to be performed for a structure (e.g., for repair and/or remodeling of the structure). For example, some embodiments of the present portable computing devices comprise: a processor; an input device; a display and memory storing instructions executable by the processor to: present via the display an input interface having a plurality of input portions each associated with a different portion of a structure; receive via the input device user selections of products that are available form a supplier, at least some of the selected products each associated with a different portion of the structure; and generate an output of information associated with the selected products, the output including for each of the selected products a unique identifier corresponding to a product record of the supplier.

Abstract: A method for treating and/or diagnosing pain and the source or type of pain, shock, and/or inflammatory conditions in a subject. A method of using a therapeutically effective amount of a DNA or RNA aptamer that shows high affinity for OLAMs to at least partially treat pain, shock, and/or inflammatory conditions in a subject. The DNA or RNA aptamer that shows high affinity for OLAMs may be coupled to a plasma protein binding compound or a pharmacologically active agent. A method of treating and or diagnosing pain, shock, and/or inflammatory conditions in a subject may include inactivating or preventing at least one linoleic acid metabolite to treat certain conditions (e.g., pain, shock, and/or inflammation) using a DNA or RNA aptamer that shows high affinity for OLAMs.

Abstract: An assembly for preventing an overdose of a charged particle beam during therapy to a patient includes a pixelated detector apparatus and a controller. The controller includes, for each pixel: a current integrator circuit that converts the local measured current into a total local detected charge integrated from a start time, the integrator circuit outputting an integrator voltage that corresponds to the total local detected charge; and a discriminator circuit that compares the integrator voltage with a reference voltage, the reference voltage corresponding to a maximum acceptable dose for the patient. A logic circuit generates an overdose fault signal if, at any of the pixels, the integrator voltage is higher than the reference voltage.

Abstract: A liquid level transducer (10) for mounting to a cryogenic tank includes a mounting head assembly (14) for connection to the tank (12) and an elongate sensing probe assembly (16) extending from the mounting head assembly (14) and into the tank. The mounting head assembly (14) has a lower mounting member (40) connected to the sensing probe assembly (16). The mounting head assembly also includes a tank mounting member (42) with a central bore (74) and a transverse wall (87) located within the bore. An upper connecting section (60) of the member (40) is threaded into the bore (74). A seal (147) is positioned between the transverse wall (87) and the upper connecting section (60). The upper connecting section (60) has a corrugated feature that receives and deforms the seal to interlock the components together and increase the sealing surface area therebetween.

Abstract: A slide fastener reinforcing strap for securing across an opening formed between first and second tapes of a slide fastener is provided. The slide fastener reinforcing strap extends from a first end to a second end along a centerline. The slide fastener reinforcing strap includes a first protrusion between the first and second ends. The first protrusion extends in a first direction which is perpendicular to the centreline.

Abstract: Various embodiments herein relate to electrochromic windows that are bird friendly, as well as methods and apparatus for forming such windows. Bird friendly windows include one or more elements that make the window visible to birds so that the birds recognize that they cannot fly through the window. Bird friendly windows can be used to minimize avian-window collisions, and therefore minimize avian deaths resulting from such collisions. In various embodiments, a window may be patterned such that the pattern is visible to birds. In these or other cases, the window may be made hazy, where the haze is visible to birds. The pattern and/or haze may be visible at wavelengths that fall in UV, and minimally noticeable (if at all) in wavelengths within the spectrum visible by humans.

Abstract: Disclosed herein is a remote operating vehicle (ROV) for use in a subterranean mining process, such as to extract material from beneath a rock layer. The ROV may be provided as a number of components each including their own umbilical cord. Each of the components may be lowered through a borehole and assembled together to form the ROV underground. Also disclosed herein is a device and method for in-line monitoring of a mining material to determine the presence of a material of interest in the mining material. The device includes conductive plates that are spaced apart. The device detects the presence of a material of interest as it passes through the spacing between the conductive plates.

Abstract: A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously.

Abstract: A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously.

Abstract: A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously.

Abstract: A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously.

Abstract: A liquid level gauge for determining the level or volume of liquid within a tank includes a mounting head adapted for connection to the tank, a gauge assembly connected to one side of the mounting head, and an elongate sensing probe assembly extending into the tank. The gauge assembly includes a rotatable gauge plate with a scale located thereon and a rotatable indicator that moves across the scale in response to a change in liquid level. The gauge plate is weighted for rotation toward a gravitational force vector for orientation with an upper surface of the liquid in the tank independent of tank tilt. The sensing probe includes a float rod with an integral coil spring hinge to facilitate installation of the gauge within the tank. A counterweight is adjustable along the float rod to fine-tune float weight or buoyancy for a particular gauge configuration and liquid type.

Abstract: A radiofrequency filter utilizing a common mode choke both as a traditional common mode choke as well as the inductance in a low pass filter. Filter topology as well as component selection is optimized for wide band operation. Common mode chokes allow differential currents to pass with little attenuation while common mode currents are effectively presented with an inductance in the common current path. This inductance is used in a low pass filter configuration to present an even higher attenuation to common mode currents. The use of multiple chokes and/or differing core materials contributes to wider band operation without pronounced resonances. The capacitance used in the low pass filter is connected in a way as to reduce its effect on the data signals while still being effective in filtering.

Abstract: Methods of modulating the properties of a cell culture expressing a protein of interest are provided. In various embodiments the methods relate to the addition of cell cycle inhibitors to growing cell cultures.

Abstract: Systems and methods for network curation are disclosed. In some embodiments, a method comprises scanning, by a mobile device, an area to identify a network device for accessing a network, receiving, by the mobile device, a network identifier associated with the network device, providing a curation indicator request to a curation server, the curation indicator request comprising the network identifier, receiving a curation indicator from the curation server, the curation indicator being retrieved, based on the network identifier, from a database of a plurality of curation indicators, the curation indicator associated with a likelihood of intent to publicly share the network by the network device, comparing the curation indicator to an access setting, the access setting indicating acceptability of network access based on the likelihood of intent to publicly share the network by the network device, and accessing the network via the network device based on the comparison.