Patents by Inventor John J. Baldwin

John J. Baldwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aralkylaminoethanol heterocyclic compounds
    Patent number: 4568679
    Abstract: Heterocyclic aminoethanols of the formulaHet--CHOH--CH.sub.2 --NH--aralkylwhere het is a 6-10 membered N heterocycle are disclosed. The compounds are useful as pharmaceuticals for reducing intraocular pressure, for use as .alpha.- and .beta.-and adrenergic blocking agents, as antihypertensive agents and for effecting bronchodilation.
    Type: Grant
    Filed: March 25, 1982
    Date of Patent: February 4, 1986
    Assignee: Merck & Co., Inc.
    Inventors: Joseph G. Atkinson, John J. Baldwin, David E. McClure
  • Amino-phenyl-thiadiazoledioxides as gastric secretion inhibitors
    Patent number: 4567191
    Abstract: Novel amino-phenyl-thiadiazoledioxides and related compounds and processes for preparing such compounds are disclosed. The compounds are useful for suppressing gastric acid secretions in mammals.
    Type: Grant
    Filed: June 7, 1983
    Date of Patent: January 28, 1986
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Adolph Pietruszkiewicz, William A. Bolhofer, William C. Lumma, Jr.
  • .beta.-Adrenergic 2-[4-(3-amino-2-hydroxypropoxy)phenyl]imidazoles
    Patent number: 4567276
    Abstract: Novel substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: June 13, 1983
    Date of Patent: January 28, 1986
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted-aminohydroxypropoxy-thiadiazoles, .beta.-blocking compositions and use
    Patent number: 4562184
    Abstract: Novel substituted-aminohydroxypropoxy-thiadiazoles and pharmaceutically acceptable salts thereof exhibit .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: April 2, 1984
    Date of Patent: December 31, 1985
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • 3-Cycloalkylamino-2-OR-propoxycyanopyridines, derivatives thereof, having anti-hypertensive activity
    Patent number: 4550117
    Abstract: 3-Cycloalkylamino-2-OR-propoxycyanopyridines having pharmacological activity are disclosed.
    Type: Grant
    Filed: January 26, 1984
    Date of Patent: October 29, 1985
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 4-Substituted amino-3-[3-alkylindoloamino-2-hydroxypropoxy] thiadiazoles, compositions and pharmaceutical use
    Patent number: 4539317
    Abstract: Novel 4-substituted amino-3-[3-alkylindoloamino-2-hydroxypropoxy] thiadiazole compounds and methods for their preparation are disclosed. These compounds and their salts exhibit pharmacological activity including antihypertensive and .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: April 9, 1984
    Date of Patent: September 3, 1985
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • Tertiary aminohydroxypropoxy substituted thiadiazoles, pharmaceutical compositions and use
    Patent number: 4539318
    Abstract: Novel tertiary aminohydroxypropoxy substituted thiadiazole compounds exhibit .alpha..sub.1 -adrenoceptor and serotonin antagonism and are also useful as antihypertensive agents.
    Type: Grant
    Filed: June 4, 1984
    Date of Patent: September 3, 1985
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • 4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and derivatives
    Patent number: 4505918
    Abstract: 4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and derivatives and acid addition salts thereof are selective central-adrenergic receptor agonists and thereby useful as antihypertensives.
    Type: Grant
    Filed: November 8, 1982
    Date of Patent: March 19, 1985
    Assignee: Merck & Co., Inc.
    Inventors: Joel R. Huff, Walfred S. Saari, John J. Baldwin
  • 2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and derivatives
    Patent number: 4506074
    Abstract: 2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and derivatives and acid addition salts thereof generally are selective .alpha..sub.2 -adrenergic receptor antagonists and .alpha..sub.1 -adrenergic receptor agonists and thereby useful as antidepressants and nasal decongestants.
    Type: Grant
    Filed: November 8, 1982
    Date of Patent: March 19, 1985
    Assignee: Merck & Co., Inc.
    Inventors: Joel R. Huff, Walfred S. Saari, John J. Baldwin
  • Amino substituted tetrahydrobenzindoles
    Patent number: 4501900
    Abstract: Aminosubstituted tetrahydrobenzindoles having antihypertensive activity are disclosed.
    Type: Grant
    Filed: March 4, 1981
    Date of Patent: February 26, 1985
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, James H. Jones, George F. Lundell
  • Aralkylaminoethanol heterocyclic compounds
    Patent number: 4486446
    Abstract: Heterocyclicaminoethanols of the formulaHet--CHOH--CH.sub.2 --NH--aralkylwhere Het is a pyrone ring are disclosed. The compounds are useful as pharmaceuticals.
    Type: Grant
    Filed: December 23, 1980
    Date of Patent: December 4, 1984
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, David E. McClure
  • Treating hypertension with aminoalkoxypyridines
    Patent number: 4474781
    Abstract: Substituted aminoalkoxypyridines of the formula ##STR1## where R.sub.1 is CN or CF.sub.3 and L is dialkylamino or six-membered N heterocycle are disclosed. The compounds are useful as antihypertensive agents.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: October 2, 1984
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • (Aralkylamino-2-OR-propoxy)heterocyclic compounds
    Patent number: 4472427
    Abstract: Compounds of the formula Het--O--CH.sub.2 --CHOR--CH.sub.2 --NHaralkyl where Het are ##STR1## disclosed. The compounds are useful as pharmaceuticals.
    Type: Grant
    Filed: August 30, 1982
    Date of Patent: September 18, 1984
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, David E. McClure
  • (3-Aralkylamino-2-or-propoxy)heterocyclic compounds
    Patent number: 4442094
    Abstract: Compounds of the formula Het--O--CH.sub.2 --CHOR--CH.sub.2 --NH-aralkyl where Het is a 10 membered N-containing ring are disclosed. The compounds are useful as pharmaceuticals.
    Type: Grant
    Filed: February 22, 1982
    Date of Patent: April 10, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Joseph G. Atkinson, John J. Baldwin, David E. McClure
  • 3-Amino-2-hydroxypropoxyaryl imidazole derivatives
    Patent number: 4440774
    Abstract: Novel substituted imidazoles of the formula ##STR1## and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: April 20, 1981
    Date of Patent: April 3, 1984
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 3-Cycloalkylamino-2-OR-propoxycyanopyridines
    Patent number: 4436740
    Abstract: 3-Cycloalkylamino-2-OR-propoxycyanopyridines having pharmacological activity are disclosed.
    Type: Grant
    Filed: July 26, 1982
    Date of Patent: March 13, 1984
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted derivatives of amino alkane diols as gastric secretion inhibitors
    Patent number: 4411899
    Abstract: There are disclosed substituted derivatives of amino alkane diols and related compounds as well as processes for the preparation of such compounds. These compounds are useful for the suppression of gastric acid secretions in mammals and compositions for such uses are also disclosed.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: October 25, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Imidazodiazines
    Patent number: 4408047
    Abstract: Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: November 19, 1981
    Date of Patent: October 4, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Preparation of epihalohydrin enantiomers
    Patent number: 4408063
    Abstract: Processes for preparing (S) or (R) epihalohydrin and an (S) substituted glycerol intermediate are disclosed.
    Type: Grant
    Filed: April 19, 1982
    Date of Patent: October 4, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, David E. McClure
  • Certain nicotinic acid esters and corresponding nicotinonitriles
    Patent number: 4393212
    Abstract: Novel substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts, certain intermediates and their preparation are disclosed. These pyridines have pharmaceutically useful properties such as .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: May 13, 1981
    Date of Patent: July 12, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello