Patents by Inventor John J. Baldwin

John J. Baldwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain quaternary ammonium-3-cyanopyridines
    Patent number: 4119630
    Abstract: Novel cyano substituted (3-loweralkylamino-2-acyl-O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: October 10, 1978
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Anti-hyperuricemia composition
    Patent number: 4111944
    Abstract: Compositions useful in the treatment of gout and hyperuricemia and containing a substituted 1,2,4-triazole as the active ingredient are provided, the triazoles being substituted at the 5 position with a pyridyl radical and at the 3 position with a phenyl or a pyridyl radical. Methods of preparing these substituted triazoles are described. Certain of the compounds are novel.
    Type: Grant
    Filed: June 21, 1977
    Date of Patent: September 5, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Frederick C. Novello, John J. Baldwin
  • 4-Substituted-2-arylimidazoles
    Patent number: 4110456
    Abstract: 4-Substituted-2-arylimidazoles, wherein the 4-substituent is sulfur containing, are disclosed. The compounds have pharmaceutical activity.
    Type: Grant
    Filed: March 1, 1977
    Date of Patent: August 29, 1978
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 1,3,5-Trisubstituted-1,2,4-triazole compounds
    Patent number: 4104393
    Abstract: Compounds useful in the treatment of asthma, the symptoms of allergy and in some instances in gout and hyperuricemia are described. The novel compounds are 1-substituted-1,2,4-triazoles being additionally substituted at the 3- and 5-positions with a pyridyl radical. Methods of preparing these tri-substituted triazoles are described.
    Type: Grant
    Filed: September 2, 1977
    Date of Patent: August 1, 1978
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 1,2,4-Triazoles
    Patent number: 4102889
    Abstract: Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agents. Compositions useful in the treatment of gout and hyperuricemia containing a substituted triazole as the active ingredient are also provided.
    Type: Grant
    Filed: November 9, 1976
    Date of Patent: July 25, 1978
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • Certain 3-cyanopyridine intermediates
    Patent number: 4096151
    Abstract: Novel 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines are vasodilators having anti-hypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: August 11, 1976
    Date of Patent: June 20, 1978
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their preparation and use
    Patent number: 4092419
    Abstract: Novel cyano substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: May 30, 1978
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their preparation and use
    Patent number: 4091104
    Abstract: Novel cyano substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: May 23, 1978
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Di-and tri-substituted 1,2,4-triazoles
    Patent number: 4071518
    Abstract: Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agents. Compositions useful in the treatment of gout and hyperuricemia containing a substituted triazole as the active ingredient are also provided.
    Type: Grant
    Filed: September 13, 1976
    Date of Patent: January 31, 1978
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines
    Patent number: 4060601
    Abstract: Novel substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines have pharmaceutical properties such as anti-hypertensive activity of rapid onset.
    Type: Grant
    Filed: June 15, 1976
    Date of Patent: November 29, 1977
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted imidazole compounds and therapeutic compositions therewith
    Patent number: 4058614
    Abstract: Substituted imidazole compounds which are useful as anti-hypertensive agents or as xanthine oxidase inhibitors.
    Type: Grant
    Filed: February 18, 1976
    Date of Patent: November 15, 1977
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Esterified-2(3-lower-alkyl-amino-propoxy)-3-cyano-pyridines and derivatives
    Patent number: 4053605
    Abstract: Novel cyano substituted (3-loweralkylamino-2-acyl-O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: June 15, 1976
    Date of Patent: October 11, 1977
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 1,3,5-Trisubstituted-1,2,4-triazole compounds
    Patent number: 4048183
    Abstract: Compounds useful in the treatment of asthma, the symptoms of allergy and in some instances in gout and hyperuricemia are described. The novel compounds are 1-substituted-1,2,4-triazoles being additionally substituted at the 3- and 5-positions with a pyridyl radical. Methods of preparing these tri-substituted triazoles are described.
    Type: Grant
    Filed: April 2, 1976
    Date of Patent: September 13, 1977
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 2-Pyrazinyl-trifluoromethylimidazoles and a method for their preparation
    Patent number: 4032522
    Abstract: 4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammonia. The 4(5)-trifluoromethylimidazoles are useful as anti-gout and anti-hyperuricemic agents.
    Type: Grant
    Filed: September 5, 1975
    Date of Patent: June 28, 1977
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 1,2,4-Triazoles
    Patent number: 4011218
    Abstract: Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agents. Compositions useful in the treatment of gout and hyperuricemia containing a substituted triazole as the active ingredient are also provided.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: March 8, 1977
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 2-(3-Tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines
    Patent number: 4000282
    Abstract: Novel 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines, their pharmaceutically their preparation are disclosed. These pyridines are vasodilators having anti-hypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: December 16, 1974
    Date of Patent: December 28, 1976
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators
    Patent number: 3984558
    Abstract: Compounds useful in the treatment of asthma, the symptoms of allergy and in some instances in gout and hyperuricemia are described. The novel compounds are 1-substituted-1,2,4-triazoles being additionally substituted at the 3- and 5-positions with a pyridyl radical. Methods of preparing these tri-substituted triazoles are described.
    Type: Grant
    Filed: November 29, 1974
    Date of Patent: October 5, 1976
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 1,3,5-Trisubstituted-1,2,4-triazole compounds
    Patent number: 3978054
    Abstract: Compounds useful in the treatment of asthma, the symptoms of allergy and in some instances in gout and hyperuricemia are described. The novel compounds are 1-substituted-1,2,4-triazoles being additionally substituted at the 3- and 5-positions with a pyridyl radical. Methods of preparing these tri-substituted triazoles are described.
    Type: Grant
    Filed: July 28, 1975
    Date of Patent: August 31, 1976
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • Pyridyl containing 1-benzenesulfonyl triazoles
    Patent number: 3963731
    Abstract: Compositions useful in the treatment of gout and hyperuricemia and containing a substituted 1,2,4-triazole as the active ingredient are provided, the triazoles being substituted at the 5 position with a pyridyl radical and at the 3 position with a phenyl or a pyridyl radical. Methods of preparing these substituted triazoles are described. Certain of the compounds are novel.
    Type: Grant
    Filed: February 6, 1975
    Date of Patent: June 15, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Frederick C. Novello, John J. Baldwin
  • Anti-hyperuricemia composition
    Patent number: 3947577
    Abstract: Compositions useful in the treatment of gout and hyperuricemia and containing a substituted 1,2,4-triazole as the active ingredient are provided, the triazoles being substituted at the 5 position with a pyridyl radical and at the 3 position with a phenyl or a pyridyl radical. Methods of preparing these substituted triazoles are described. Certain of the compounds are novel.
    Type: Grant
    Filed: January 8, 1975
    Date of Patent: March 30, 1976
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello