Patents by Inventor John J. Baldwin

John J. Baldwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridyloxypropanolamines
    Patent number: 4210653
    Abstract: Pyridyloxypropanolamines, their preparation and use as antihypertensive agents is disclosed.
    Type: Grant
    Filed: June 27, 1978
    Date of Patent: July 1, 1980
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, David E. McClure
  • N-Aralkyl containing cyanopyridines
    Patent number: 4208416
    Abstract: N-Aralkylamino-OR-propoxycyanopyridines having pharmacological activity are disclosed.
    Type: Grant
    Filed: June 27, 1978
    Date of Patent: June 17, 1980
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 3-Amino-2-or-propoxy-tetrahydronaphthyl or indanyl-substituted imidazoles and use
    Patent number: 4199580
    Abstract: Novel 3-amino-2-OR-propoxy-tetrahydronaphthyl or indanyl substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: July 14, 1978
    Date of Patent: April 22, 1980
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 1,2,4-Triazoles
    Patent number: 4198513
    Abstract: Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agents. Compositions useful in the treatment of gout and hyperuricemia containing a substituted triazole as the active ingredient are also provided.
    Type: Grant
    Filed: April 7, 1978
    Date of Patent: April 15, 1980
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • 4-Substituted-2-arylimidazoles
    Patent number: 4179512
    Abstract: 4-Substituted-2-arylimidazoles, wherein the 4-substituent is sulfur containing, are disclosed. The compounds have pharmaceutical activity.
    Type: Grant
    Filed: May 26, 1978
    Date of Patent: December 18, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • Novel naphthyridines
    Patent number: 4176183
    Abstract: Novel naphthyridines having a 3-amino-2-OR-propoxy substituent are disclosed. The compounds have .beta.-adrenergic blocking and immediate onset antihypertensive activities.
    Type: Grant
    Filed: July 17, 1978
    Date of Patent: November 27, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • 2-Amino propanol isothiozol-3-ones
    Patent number: 4169835
    Abstract: Novel isothiazoles having a 3-amino-2-OR-propoxy or - propyl substituent are disclosed. The isothiazoles have pharmaceutical activity.
    Type: Grant
    Filed: March 6, 1978
    Date of Patent: October 2, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • Certain imidazo(1,2a)pyridine derivatives
    Patent number: 4166851
    Abstract: Novel imidazopyridines, -pyrazines, -pyrimidines and -pyridazines having a 3-amino-2-OR-propoxy substituent, are disclosed. The compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: May 16, 1977
    Date of Patent: September 4, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, William C. Lumma, Jr.
  • Substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, and use
    Patent number: 4156004
    Abstract: Novel cyano substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: May 22, 1979
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 1,2,4-Triazoles
    Patent number: 4156085
    Abstract: Triazoles substituted at the 3 and 5 positions having an optional substituent in the 1 position are provided. Methods of preparing the novel substituted triazoles are described. The substituted triazoles are useful as anti-gout and anti-hyperuricemic agents. Compositions useful in the treatment of gout and hyperuricemia containing a substituted triazole as the active ingredient are also provided.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: May 22, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • Substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their preparation and use
    Patent number: 4152437
    Abstract: Novel cyano substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: May 1, 1979
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, antihypertensive compositions and methods containing same
    Patent number: 4151284
    Abstract: Novel cyano substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: January 12, 1978
    Date of Patent: April 24, 1979
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Substituted (3-loweralkylamino-2-R.sub.1 0-propoxy)pyridines, their preparation and use
    Patent number: 4145425
    Abstract: Novel cyano substituted (3-loweralkylamino-2-R.sub.1 0-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: February 17, 1978
    Date of Patent: March 20, 1979
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Heterocycle substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines
    Patent number: 4144343
    Abstract: Heterocycle substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines have pharmaceutical properties such as anti-hypertensive activity of rapid onset.
    Type: Grant
    Filed: January 4, 1978
    Date of Patent: March 13, 1979
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • 3-Cyano-2-pyridinyloxymethyl-oxazolidine derivatives
    Patent number: 4139535
    Abstract: Novel 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines are vasodilators having anti-hypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: September 2, 1977
    Date of Patent: February 13, 1979
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 3-Amino-2-OR-propoxyaryl substituted imidazoles
    Patent number: 4134983
    Abstract: Novel 3-amino-2-OR-propoxyaryl substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: December 17, 1975
    Date of Patent: January 16, 1979
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • Trifluoromethylimidazoles and a method for their preparation
    Patent number: 4125530
    Abstract: 4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammonia. The 4(5)-trifluoromethylimidazoles are useful as anti-gout and anti-hyperuricemic agents.
    Type: Grant
    Filed: February 2, 1977
    Date of Patent: November 14, 1978
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Frederick C. Novello
  • Novel substituted pyridines, their preparation and pharmaceutical use
    Patent number: 4125618
    Abstract: Novel substituted (3-loweralkylamino-2-R,o-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines have pharmaceutical properties such as anti-hypertensive activity of rapid onset.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: November 14, 1978
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin
  • 3-Amino-2-oxy-propoxy-substituted isothiazoles
    Patent number: 4119718
    Abstract: Isothiazoles having a 3-amino-2-acycloxy-propoxy or a 3-amino-2-hydroxy-propoxy substituent and 2-(3-amino-2-hydroxypropyl) isothiazole-3-ones are disclosed. These compounds have .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: May 2, 1977
    Date of Patent: October 10, 1978
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • Substituted (3-loweralkylamino-2-r.sub.1 o-propoxy)pyridines, their preparation and use
    Patent number: 4119721
    Abstract: Novel cyano substituted (3-loweralkylamino-2-acyl-O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. The pyridines are vasodilators having antihypertensive activity of rapid onset and extended duration and reduced tendency to cause undesirable tachychardia; they are also .beta.-adrenergic blocking agents.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: October 10, 1978
    Assignee: Merck & Co., Inc.
    Inventor: John J. Baldwin