Abstract: A method for forming a plurality of precision holes in a substrate by drilling, including affixing a sacrificial cover layer to a surface of the substrate, positioning a laser beam in a predetermined location relative to the substrate and corresponding to a desired location of one of the plurality of precision holes, forming a through hole in the sacrificial cover layer by repeatedly pulsing a laser beam at the predetermined location, and pulsing the laser beam into the through hole formed in the sacrificial cover layer. A work piece having precision holes including a substrate having the precision holes formed therein, wherein a longitudinal axis of each precision hole extends in a thickness direction of the substrate, and a sacrificial cover layer detachably affixed to a surface of the substrate, such that the sacrificial cover layer reduces irregularities of the precision holes.

Abstract: An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.

Abstract: A kit of components for a medical infusion includes a syringe having a syringe body with a liquid chamber having a volumetric capacity in a range of 5 ml to 30 ml, large bore tubing having an inner diameter greater than 3 mm and less than or equal to 6 mm and a length in a range of 4 feet to 10 feet, a valve with an axially extending valve body with opposing first and second ends, and a package holding the syringe pre-attached to the valve body and the large bore tubing in a sterile condition to thereby provide components in a ready-to-use configuration for insertion of the syringe and valve into an infusion device. The valve body includes an inlet tube residing between the first and second ends of the valve body and an exit port on the first end of the valve body.

Abstract: A method of giving a charitable gift includes making a selection of one or more items from a computing device, the selection being associated with an online platform; receiving a printed receipt, the printed receipt having an identification code associated therewith; transferring the printed receipt to an individual; and providing the individual with the selection of one or more items from a brick and mortar store; the identification code is associated with the selection of one or more items.

Abstract: An augmented reality optical system comprises a waveguide structure that includes a waveguide layer supported by a substrate. An input grating and an output grating reside within the waveguide layer and are laterally spaced apart. Input light from a display is made incident upon the input grating. The input light is coupled into the waveguide layer and travels therein as multiple guided modes to the output grating. The input and output gratings provide phase matching so that the guided modes are coupled out of the waveguide layer by the output grating continuously along the output grating to form output light. Meantime, light from a scene is transmitted perpendicularly through the output grating so that the output light and the light from the scene are combined by the eye of a user to form an augmented reality image.

Abstract: A loop flushing valve includes a valve body, a fluid passage plug, and a poppet. The valve body includes an internal shoulder and a bore. The fluid passage plug is disposed in the bore and includes a fluid passage in fluid communication with the bore and a system fluid passage. The poppet is captured between the internal shoulder and the fluid passage plug and extends through the valve body.

Abstract: Disclosed herein are methods for gene inactivation or rescue by cutting genomic DNA at regions of putative exon splicing enhancers with CRISPR-type enzymes.

Abstract: A nozzle for attachment to a hair dryer includes a body and an airflow guiding member. The body has an internal surface which defines an airflow duct which extends from an air inlet end for receiving an airflow to a slot-shaped air outlet end of the body. The internal surface has opposing first surface sections which taper inwardly towards the air outlet end, and opposing second surface sections which taper outwardly towards the air outlet end. The airflow guiding member guides a first portion of a received airflow towards one of the second surface sections, and a second portion of the received airflow towards the other of the second surface sections.

Abstract: A glass wafer having a first major surface, a second major surface that is parallel to and opposite of the first major surface, a thickness between the first major surface and the second major surface, and an annular edge portion that extends from an outermost diameter of the glass wafer toward the geometrical center of the glass wafer. The glass wafer has a diameter from greater than or equal to 175 mm to less than or equal to 325 mm and a thickness of less than 0.350 mm. A width of the edge portion is less than 10 mm.

Abstract: A magnetizable glass ceramic composition including: a continuous first glass phase including SiO2, B2O3, P2O5, and R2O; a discontinuous second glass phase including at least one of SiO2, B2O3, P2O5, R2O, or mixtures thereof; and a discrete magnetizable crystalline phase dispersed in the discontinuous second glass phase, where R2O is selected from at least one of K2O, Li2O, Na2O, or mixtures thereof. Also disclosed are a method of making and a method of using the magnetizable glass ceramic composition.

Abstract: Disclosed are various embodiments for high diffraction efficiency phase gratings. An organized set of nanoparticles are embedded within a polymer composite. The polymer composite is then etched to generate one or more trenches in the polymer composite that correspond to the organized set of nanoparticles.

Abstract: An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.

Abstract: A filter device has a single hub and a plurality of filter struts extending in a first longitudinal direction. A plurality of wire loops extend in a second longitudinal direction opposite the filter struts. The filter struts and wire loops each engage the vessel wall of a body lumen when deployed. The wire loops limit the filter device from becoming tilted and embedded in the vessel wall. A retrieval device includes a sheath and a snaring mechanism. The snaring mechanism engages a hook member of the filter and the sheath envelopes the wire loops and filter struts. The sheath will cause the wire loops to bend and fold over the filter struts during retrieval such that the wire loops and filter struts extend in the same longitudinal direction after being enveloped by the sheath.

Abstract: A retrieval system for a medical device includes an access sheath, a clot catch with an attached mesh, and a filter catch having an attached retrieval member. The filter catch is translatable within clot catch, and the clot catch is translatable within the access sheath. The mesh is expandable into engagement with a body vessel during retrieval of the medical device. The mesh captures emboli that are dislodged during retrieval of the device. The device is captured by the clot catch during retrieval, and the clot catch is subsequently captured by the access sheath. The system can further include an inner sheath translatable within the clot catch, with the inner sheath capturing the medical device and the clot catch capturing the inner sheath.

Abstract: According to one embodiment, a method for producing a coated glass article may include applying an anti-reflective coating onto a glass substrate. The glass substrate may include a first major surface, and a second major surface opposite the first major surface. The anti-reflective coating may be applied to the first major surface of the glass substrate. A substrate thickness may be measured between the first major surface and the second major surface. The glass substrate may have an aspect ratio of at least about 100:1. The coated glass article may have a reflectance of less than 2% for all wavelengths from 450 nanometers to 700 nanometers. The anti-reflective coating may include one or more layers. The cumulative layer stress of the anti-reflective coating may have an absolute value less than or equal to about 167,000 MPa nm.

Abstract: A diffuser includes an air inlet for receiving an airflow from a hair dryer, an external grille having a plurality of air outlets for emitting at least part of the airflow from the diffuser, and an internal grille located between the air inlet and the external grille.

Abstract: A system, method, and computer program product provides recommendations with a mobile device recommendation system to a user of a mobile device. The recommendation system collects data set A comprising ambient sensor data from sensors of a plurality of mobile devices of a selected population located remote from the mobile device of the user. A data set B is also collected over the network wherein data set B comprises social media data transmitted from and/or related to a plurality of venues and/or events located within a selected geographic area. A data set C comprising data received from the user of the mobile device and/or the mobile device of the user is also collected. The data sets A, B, and C are analyzed and a recommendation is provided of at least one of the venues and/or events within the selected geographic area based upon the analyzed data.

Abstract: A magnetizable glass ceramic composition including: a continuous first glass phase including SiO2, B2O3, P2O5, and R2O; a discontinuous second glass phase including at least one of SiO2, B2O3, P2O5, R2O, or mixtures thereof; and a discrete magnetizable crystalline phase dispersed in the discontinuous second glass phase, where R2O is selected from at least one of K2O, Li2O, Na2O, or mixtures thereof. Also disclosed are a method of making and a method of using the magnetizable glass ceramic composition.