Abstract: Provided are methods, compositions and kits for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host.

Abstract: Systems and methods for improved radiation treatment planning can employ hierarchical constrained optimization with relaxed constraints also referred to herein after as expedited hierarchical constrained optimization (ECHO). The systems and methods described herein employ a combination of constrained optimization and a correction loop involving unconstrained optimization to enhance the speed and efficiency of the radiation treatment planning process and improve the accuracy and quality of resulting radiation treatment plans. The use of a hierarchical constrained optimization approach leads to less complex and faster to solve optimization problems. The correction loop allows for compensating for optimization error associated with the sequence of constrained optimizations by incorporating such error in an unconstrained optimization. Hard and soft dose volume constraints can be efficiently incorporated.

Abstract: A cuvette for collecting a blood sample, the cuvette comprising: a main body; a collection aperture formed within the main body; an ingress aperture, allowing communication between a first end of the collection aperture and an exterior of the cuvette; and a retention chamber formed within the main body and adjacent a second end of the collection chamber, which is generally opposite the first end thereof, wherein: the collection chamber has a first depth, which is the same or substantially the same across the collection chamber, from the first end to the second end thereof; and the retention chamber has a second, greater depth.

Abstract: Systems and methods for multi-modal, multi-resolution deep learning neural networks for segmentation, outcomes prediction and longitudinal response monitoring to immunotherapy and radiotherapy are detailed herein. A structure-specific Generational Adversarial Network (SSGAN) is used to synthesize realistic and structure-preserving images not produced using state-of-the art GANs and simultaneously incorporate constraints to produce synthetic images. A deeply supervised, Multi-modality, Multi-Resolution Residual Networks (DeepMMRRN) for tumor and organs-at-risk (OAR) segmentation may be used for tumor and OAR segmentation. The DeepMMRRN may combine multiple modalities for tumor and OAR segmentation. Accurate segmentation is may be realized by maximizing network capacity by simultaneously using features at multiple scales and resolutions and feature selection through deep supervision. DeepMMRRN Radiomics may be used for predicting and longitudinal monitoring response to immunotherapy.

Abstract: A modular bidet attachment. The modular bidet attachment includes mounting discs that mount to a bidet chassis via a snap fit mechanism. The mounting discs include openings that are less than half the length of the diameter of the mounting discs. The mounting discs are configured to rotate after being mounted to the chassis.

Abstract: Described herein is a method of preparing an aminoalkyl-substituted disiloxane. The method includes forming a mixture including a di- or polyamine containing at least one primary amine group and a silane; reacting the mixture in a first reaction; adding a hydrolysis agent to the mixture; and reacting the mixture in a second reaction to form the aminoalkyl-substituted disiloxane. Also described herein is an aminoalkyl-substituted disiloxane prepared according to the method.

Abstract: Methods and apparatus for customers key protection for cloud native deployments. Compute resources for a compute platform comprising platform hardware including one or more processors are allocated to one or more customers that use the compute resources to execute applications and/or services used to perform customer workloads. The compute platform includes a per-part device key that is used to generate hardware protected key used by the applications and services. Mechanisms are provided to ensure hardware protected keys can only be accessed by associated customers and/or customer applications and services, while preventing other customers and/or applications and services from accessing the hardware protected keys. The hardware protected keys include keys employing various forms of RSA and ECC Wrapped Private Keys (WPKs) including RSA WPKs, RSA Chinese Remainder Theorem CRT WPK and ECC WPKs.

Abstract: A coiled tubing heating head tool system includes a tool connected at a connector to a terminal end of coiled tubing, the tool having a tubular extending from the connector to a heating head having a heater, a fluid passage extending from a discharge port in the tubular through the connector into the coiled tubing, and a one-way valve in the fluid passage between the discharge port and the connector, and a power cable electrically coupled to the heater and extending through the tubular, the connector, and the coiled tubing, to an electrical power source.

Abstract: An apparatus operating as a certificate authority (CA) is described. The apparatus can perform operations including receiving, from a plurality of requesting devices, a request to join a group. The request can include identification information for the group and attestation evidence for the plurality of requesting devices. Responsive to receiving the request, the apparatus can provide a group certificate for the group to the plurality of requesting devices.

Abstract: The invention is that of a system and method of generating an individual compliance score based on one or more background checks that is useful in determining the compliance levels of service providers based on selected criteria. The individual compliance scores are the result of a matrix comparison of a background check score against industry standards to provide greater weight to areas of specific interest depending on the industry. An application program interface may be installed on a user system to allow individual compliance scores and corresponding unique identifiers to be visible to users of the system. Access and security controls are provided, with users being in network communication with the system. The methods enabled by the system allow for rapid real-time service provider qualification without the need for time consuming background audits. A system of the present invention may be presented as a feature of an existing mobile application.

Abstract: A hydraulic control system for blowout preventers systems, frack valves and chokes, and related wellhead and control equipment used in oil and gas well drilling operations. The hydraulic control system can include one or more hydraulic control valves or pressure regulators including an internal, linear slider and pairs of seal rings. Lapped and polished surfaces of the seal rings and sliders can form a dynamic metal-to-metal seal within the hydraulic control valves or pressure regulators.

Abstract: A method of filtering a URL against a blacklist includes receiving at least a portion of a Uniform Resource Locator (URL), and determining which of a plurality of XOR filters is applicable to the received at least a portion of a URL, where each of the plurality of XOR filters represents a different portion of a URL blacklist. At least a portion of a URL is forwarded to the applicable one of the plurality of XOR filters, and the at least a portion of the URL is processed in the applicable one of the plurality of XOR filters to produce an output indicating whether the URL is likely on the blacklist.

Abstract: A transformer monitoring device has one or more voltage sensors and/or one or more current sensors integral with a housing for detecting a voltage of a power cable of a transformer. The transformer monitoring device can be configured to monitor voltage levels, and cause alerts to be issued if voltage levels drop and/or spike beyond operator-established tolerance(s).

Abstract: Provided are methods, compositions and kits for depleting host nucleic acid in a biological sample, said sample having been previously obtained from an animal host.

Abstract: Improved inspection techniques are described herein for checking for the presence of and identifying surface defects on a honeycomb body. The improved inspection utilizes measurement of travel of an outer surface of the honeycomb body to collect images of the outer surface. The images are combined into a composite image showing the outer surface of the honeycomb body. The composite image is analyzed to identify surface defects.

Abstract: A thermoplastic film which exhibits elastic-like behavior along at least one axis when stretched or elongated and then released. The thermoplastic film comprises a plurality of raised rib-like elements extending in a direction perpendicular to a main surface of the thermoplastic film. The thermoplastic film further includes a plurality of web areas positioned about the plurality of raised rib-like elements. The plurality of raised rib-like elements and plurality of web areas are arranged in a complex pattern. The complex pattern provides visual and tactile cues as the films are stretched or elongated. The complex pattern can cause the thermoplastic film to have a complex stretch profile.

Abstract: According to examples, a lens configuration for a head-mounted display (HMD) device may include a base platform made from glass or plastic, an antenna layer deposited onto the base platform, an optical polymer film deposited onto the antenna layer, and a lens layer deposited onto the optical polymer film through a 3D printing technique. The antenna layer may include a transparent antenna embedded into or deposited onto a transparent layer. The lens layer may be 3D printed as multiple partial layers to have a shape that matches a prescription for the lens layer.

Abstract: In some embodiments, the present disclosure relates to a system. The system includes a substrate and a fluid capture material formed on one or more surfaces of the substrate. The fluid capture material includes a sorbent material that binds one or more fluids, the one or more fluids comprising water, carbon dioxide, sulfur oxides, or a combination thereof. The fluid capture material also includes one or more binder materials, wherein the binder material is at least partially cross-linked.

Abstract: The present disclosure provides an automated method of producing genetically modified immune cells, including chimeric antigen receptor T (CAR T) cells, utilizing a fully-enclosed cell engineering system.

Abstract: A surgical handpiece system for performing measurement functions and surgical operations. The system includes a handpiece assembly. The handpiece has a handpiece housing and a drive cannula rotatably coupled to the handpiece housing. The drive cannula extends along an axis and is configured to receive torque from a motor. A surgical attachment module has an attachment housing removably coupleable to the handpiece housing. The surgical attachment module has a drive shaft rotatably coupled to the surgical attachment housing and configured to receive torque from the drive cannula to operate an end effector. A measurement module has a measurement housing removably coupleable to the handpiece housing. The measurement module is configured to perform measurement functions associated with operation of the handpiece assembly.