Abstract: A modified adenovirus, in particular Enadenotucirev (EnAd), armed with a bispecific T cell engager (BiTE™) comprising at least two binding domains, wherein at least one of the domains is specific for a surface antigen on a T-cell of interest. Also provided are a composition, such as a pharmaceutical formulation comprising the virus, use of the virus and virus formulations for treatment, such as in the treatment of cancer. The disclosure also extends to processes for preparing the virus.

Abstract: A fiber optic splitter terminal for a fiber optic distribution network includes a terminal enclosure forming an interior compartment. At least one fiber optic adapter panel is disposed in the terminal enclosure, with a first side facing a first sub-compartment and a second side facing a second sub-compartment, to separate the interior compartment into two distinct areas. A first fiber optic adapter is disposed in the fiber optic adapter panel, and a plurality of second fiber optic adapters are also disposed in the fiber optic adapter panel. One or more splitter modules are disposed at least partially in the first sub-compartment, each comprising a splitter enclosure and a splitter disposed in the splitter enclosure, the splitter having an input leg configured to be optically connected to the first fiber optic adapter and a plurality of output legs optically configured to be connected to the second fiber optic adapters.

Abstract: A nested insulated packaging assembly comprising an outer box and a thermal liner. The outer box includes an outer top side wall, an outer bottom side wall, and a plurality of outer lateral side walls. The thermal liner includes a terminal top end, a bend line, a top fold defined between the terminal top end and the bend line, and a back fold. The top fold is foldable relative to the back fold at the bend line. The back fold contacts one of the outer lateral side walls of the outer box. The thermal liner includes a thermal control material extending across the bend line.

Abstract: A system and method for controlling delivery of gas, including a gas pipeline network having at least one gas production plant, at least one gas receipt facility of a customer, a plurality of pipeline segments, and a plurality of control elements, one or more controllers, and one or more processors. The hydraulic feasibility of providing an increased flow rate of the gas to the gas receipt facility of the customer is determined using a linearized pressure drop model. A latent demand of the customer for the gas is estimated using a latent demand model. Based on the hydraulic feasibility and the latent demand, a new gas flow request rate from the customer is received. A network flow solution is calculated based on the new gas flow request rate. The network flow solution is associated with control element setpoints used by a controller to control one or more control elements.

Abstract: The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain miRNAs described herein and/or by therapeutically increasing the level of those miRNAs.

Abstract: A tooth cutting guide or tooth ridge lap guide for processing at least one prefabricated artificial tooth from a set of prefabricated artificial teeth using a subtractive processing method, the tooth cutting guide comprising a base body, at least one retainer for receiving and positioning the at least one prefabricated artificial tooth, which is formed in the base body, wherein an inner surface of each of the at least one retainer form fits to a first surface area of one of the at least one prefabricated artificial tooth from the set of prefabricated artificial teeth, and at least one through hole which is located in the at least one retainer, wherein the at least one through hole exposes at least a part of a basal surface or an occlusal surface of the one of the at least one prefabricated artificial tooth if inserted into the corresponding retainer.

Abstract: A shopping cart with sensor system is used by customers of a retail store to collect and scan items to be purchased. The shopping cart with sensor system includes a shopping cart and a shopping cart sensor system. Items to be purchased are placed in the shopping cart, where they are automatically scanned by the sensor system. The shopping cart sensor system includes a frame and a sensor coupled to the frame. The frame rotates with respect to the shopping cart so that the sensor can collect product information from items in the shopping cart. A first and a second light bar and a microcomputer are also coupled to the frame. The product information is used to ring up the items a customer wishes to purchase, so the customer does not have to visit a checkout station to have their items rung up.

Abstract: A sleeve for a garment, comprising: a front panel attached to a back panel along respective first and second side edges thereof, the back panel having upper and lower vents formed proximate an elbow portion thereof; and, upper and lower flaps formed on the back panel above and overlapping the upper and lower vents, respectively; wherein the upper and lower flaps are moveable between a closed position when the sleeve is straight through the elbow portion and an opened position when the sleeve is bent at the elbow portion to thereby allow increased airflow through the upper and lower vents when the garment is in use.

Abstract: A solar monitoring system for measuring solar radiation intensity comprising a tracking unit having two-axis movement comprising, an image capturing head mounted with first and second irradiation measuring units, and a controller. The first irradiation measuring unit comprises a direct normal irradiance (DNI) sensor and the second irradiation measuring unit includes a diffuse horizontal irradiance (DHI) sensor and a global horizontal irradiance (GHI) sensor. The controller receives inputs from the sensors or a software program configured to control orientation of the image capturing head so that the DNI sensor is always exposed to the sun, and the shading disc is always directly between the DHI sensor and the sun.

Abstract: A fiber optic terminal includes an enclosure defining an interior space having a plurality module holders and at least one module removably positioned in one of the plurality of module holders. Each removable module may include at least one input adapter and a plurality of output adapters. Each removable module may also include one or more splitters, cable storage components, pass-through components, or parking components. The fiber optic module may also include first and second arms extending from the front side of the body and a handle coupled to the first and second arms. The handle may be rotatable between a closed position and an open position, and may also be removable from the first and second arms when the handle is in the open position.

Abstract: A method includes receiving at a management component of an FPGA a persona change request and issuing a request by the management component to a reconfigurable PR slot of the FPGA to change a first persona of a first circuit device of the FPGA to a second persona of a second circuit device of the FPGA. The management component, the reconfigurable PR slot, and the first and second circuit devices are configured in the FPGA core. The method includes switching by the reconfigurable PR slot the first persona to the second persona. The method includes issuing a request by the management component, a host re-enumeration of the reconfigurable PR slot, triggering by the host a re-enumeration component a re-enumeration of the reconfigurable PR slot, and exposing by the reconfigurable PR slot the second persona such that the host is reconfigured to recognize the second circuit device.

Abstract: A safety device is configured to be attached to components in an electrical substation to provide a physical and visual barrier between de-energized components and energized components in the electrical substation. The safety may include a safety barrier board formed from an electrically insulating material and configured to be attached to fastening devices that attach the safety barrier board to components in the substation. Each fastening device may be an inverted-J-hook configured to be attached to a surface of the safety barrier board or a coupling link attached to a variable length fastening component and an attachment hook.

Abstract: Methods for fabricating semiconductor devices incorporating an activated p-(Al,In)GaN layer include exposing a p-(Al,In)GaN layer to a gaseous composition of H2 and/or NH3 under conditions that would otherwise passivate the p-(Al,In)GaN layer. The methods do not include subjecting the p-(Al,In)GaN layer to a separate activation step in a low hydrogen or hydrogen-free environment. The methods can be used to fabricate buried activated n/p-(Al,In)GaN tunnel junctions, which can be incorporated into electronic devices.

Abstract: A fiber optic module for use in a fiber optic terminal. The fiber optic module includes a body having a front end, a first body section including a first group of adapters on the front end and a first fiber routing arm having a first fiber retaining element at a free end of the first routing arm, and a second body section in stacked alignment with the first body section, wherein the second body section includes a second group of adapters on the front end and a second fiber routing arm having a second fiber retaining element at a free end of the second routing arm. The first body section and the second body section define an internal volume containing an optical splitter. The fiber optic module may also include a handle coupleable to the first body section.

Abstract: Systems and methods for autonomous vehicle testing are provided. In one example embodiment, a computer-implemented method includes presenting, by a computing system, a visual representation of a simulated environment via a user interface on a display device. The simulated environment includes a simulated object and a simulated autonomous vehicle. The method includes initiating, by the computing system, a simulation run associated with the simulated environment. The method includes, during the simulation run, obtaining, by the computing system, data indicative of a user input associated with a motion of the simulated object within the simulated environment. The method includes, in response to the user input and during the simulation run, controlling, by the computing system, the motion of the simulated object within the simulated environment based at least in part on the data indicative of the user input. The method also includes controlling the simulated autonomous vehicle within the simulated environment.

Abstract: Unmanned aerial vehicles (UAVs) may facilitate insurance-related tasks. UAVs may actively be dispatched to an insured asset and the area surrounding an insured asset, such as with the policyholder or insured's permission and collect data related to the insured asset, such as images, video, audio, weather conditions, thermal signatures, wood and soil samples, etc., and transmit this data to a computing device. The computing device may be associated with and/or utilized by an insurance provider to perform insurance-related tasks, such as processing the data to determine an amount of risk associated with the insured asset. If the amount of risk has increased, the computing device may provide a recommendation to a mobile device of the policyholder on how to reduce the risk such that corrective action may be taken. Insurance discounts may be provided based upon following recommendations that mitigate risk.

Abstract: Systems and methods are directed to compensating for time delays. In one example, a system includes one or more processors and memory including instructions that, when executed by the one or more processors, cause the one or more processors to perform operations. The operations include obtaining first pose data indicative of a pose of a vehicle; obtaining first control data indicative of a first vehicle control command that has yet to affect control of the vehicle; determining, based at least partially on the first pose data and the first control data, predicted pose data indicative of an estimate of a pose of the vehicle that will result after the vehicle control command affects control of the vehicle; and generating, based at least partially on the predicted pose data, second control data indicative of a second vehicle control command to be applied subsequent to the first vehicle control command.

Abstract: An insulation packaging assembly includes: a box including a top side wall, an bottom side wall, and a plurality of lateral side walls; a first insulation liner contacting a one of the lateral side walls of the box, the first insulation liner including a left fold, a center fold, and a right fold; and a second insulation liner contacting a second of the lateral side walls of the box, the second insulation liner including a top fold, a back fold, and a bottom fold, the top fold of the second insulation liner positioned between the left fold and the right fold of the first insulation liner.

Abstract: A method for constructing a dictionary to represent data from a training data set comprising: modeling the data as a linear combination of columns; modeling outliers in the data set via deterministic outlier vectors; formatting the training data set in matrix form for processing; defining an underlying structure in the data set; quantifying a similarity across the data; building a Laplacian matrix; using group-Lasso regularizers to succinctly represent the data; choosing scalar parameters for controlling the number of dictionary columns used to represent the data and the number of elements of the training data set identified as outliers; using BCD and PG methods on the vector-matrix-formatted data set to estimate a dictionary, corresponding expansion coefficients, and the outlier vectors; and using a length of the outlier vectors to identify outliers in the data.

Abstract: Systems and methods are directed to monitoring the status of a vehicle controller or other autonomy system during operation of an autonomous vehicle. In one example, a system includes one or more processors; and memory storing instructions that, when executed by the one or more processors, cause the one or more processors to perform operations. The operations include obtaining a message from a vehicle controller. The operations further include, based at least partly on the message, determining whether a failure mode exists. The operations further include providing, in response to determining the failure mode exists, one or more commands to implement a safety measure response for the autonomous vehicle.