Abstract: The invention relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.

Abstract: Provided are a method and apparatus for generating ultra-high-quality digital data. A method for generating digital data includes identifying information on a target disposed at a specific position, controlling a movement of a first device to photograph two-dimensional image data for a partial region of the identified target, determining whether the two-dimensional image data for the partial region of the target photographed through a camera mounted on the first device corresponds to an entire region of the target, and controlling a movement of a second device loaded with the target when the two-dimensional image data for the partial region of the photographed target does not correspond to the entire region of the target.

Abstract: Disclosed are an optical modulation device and a phase modulation method using the same. The optical modulation device includes a reflection plate, an insulating film over the reflection plate, dielectric patterns aligned on the insulating film in a first direction and extended in parallel in a second direction intersecting the first direction, and first and second graphene patterns provided between the dielectric patterns and alternately aligned in the first direction. The dielectric patterns and the first and second graphene patterns fully cover the top of the insulating film. Two dielectric patterns adjacent to each other in the first direction with one of the first graphene patterns interposed therebetween form one dielectric pattern pair. The dielectric pattern pair is provided in plural. The dielectric pattern pairs are isolated from each other in the first direction with one of the second graphene patterns interposed therebetween.

Abstract: The invention relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.

Abstract: Disclosed herein are a key generation apparatus and method based on machine learning. The key generation method includes generating, by first and second key generation apparatuses, first and second commit values, and uploading the first commit value and the second commit value to an external repository, training, by the first and second key generation apparatuses, a neural network so as to match weight values with each other, sharing, by the first and second key generation apparatuses, the first and second commit values with each other, comparing shared first and second commit values with uploaded commit values, and then verifying the commit values, and when verification of the commit values has succeeded, generating, by the first and second key generation apparatuses, hash values using the matched weight value, verifying whether the hash values are identical to each other, and generating a session secret key based on a result of verification.

Abstract: A method of providing a search index based on a Bloom filter in a distributed data sharing environment based a block chain includes generating, by a data generating device, Bloom filters used as the search index on the basis of a hash value calculated by applying a hash function to a keyword set for searching for data which is to be shared, generating, by a block providing server, a new block on the basis of the Bloom filters and the data received from the data generating device and performing proof of work (PoW) on the new block, for adding the new block to the block chain, and distributing, by a block distributing server, block chain data including the new block added to the block chain.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell comprising the CD19 CAR as described herein, in combination with one or more B-cell inhibitors, e.g., inhibitors of one or more of CD10, CD20, CD22, CD34, CD123, FLT-3, ROR1, CD79b, CD179b, or CD79a. The disclosure additionally features novel antigen binding domains and CAR molecules directed to CD20 and CD22, and uses, e.g., as monotherapies or in combination therapies. The invention also provides kits and compositions described herein.

Abstract: A moisture permeability measuring device includes a first body member including a seating part, a flexible bottom plate to be arranged on the seating part, a flexible top plate to be arranged on the bottom plate, a holder part to fix a lower edge portion of the bottom plate and an upper edge portion of the top plate, and a second body member to be arranged on the holder part and having a through-hole defined in a region overlapping the top plate, and an area of the seating part on a plane is smaller than an area of the bottom plate on the plane.

Abstract: Provided is a cellulose derivative composition for a secondary battery binder, a method of preparing a composition for a secondary battery electrode, including the same, and a secondary battery including the same. According to the inventive concept, the cellulose derivative composition for a secondary battery binder may include a compound represented by Formula 1 below.

Abstract: Provided is a composite electrode for an all-solid-state secondary battery including a first active material and a second active material, wherein the first active material and the second active material include different materials from each other, and the content of the first active material is 50 vol % to 98 vol % based on the total volume of the first active material and the second active material, the first active material has a volume change rate of 0 vol % to 30 vol % according to volume expansion/contraction during a charging/discharging process, and the second active material has a volume change rate of 35 vol % to 1000 vol % according to volume expansion/contraction during a charging/discharging process.

Abstract: Provided is a cellulose derivative composition for a secondary battery binder, a method of preparing a composition for a secondary battery electrode, including the same, and a secondary battery including the same. According to the inventive concept, the cellulose derivative composition for a secondary battery binder may include a compound represented by Formula 1 below.

Abstract: Provided is a method for manufacturing a solid secondary battery, wherein the method includes forming a composite electrolyte film, and forming a positive electrode and a negative electrode respectively on both surfaces of the composite electrolyte film. The forming of a composite electrolyte film includes preparing inorganic ion conductor powder coated with an ion resistance layer, removing the ion resistance layer to expose the surface of the inorganic ion conductor powder, mixing the inorganic ion conductor powder with an organic ion conductor and a solvent to prepare a composite electrolyte solution, and removing the solvent from the composite electrolyte solution.

Abstract: Provided is a method of preparing a coating composition for a separator of a secondary battery, and particularly a method including dispersing a first monomer and a surfactant in a solvent to form micelles, adding a first initiator to the solvent and performing first polymerization reaction to form a precursor solution including an emulsion-type binder, and adding a second monomer and a second initiator to the precursor solution and performing second polymerization reaction to form an aqueous binder solution including a solution-type binder, wherein the emulsion-type binder has a core shape, the solution-type binder has a shell shape wrapping the emulsion-type binder, and the emulsion-type binder and the solution-type binder are chemically bonded.

Abstract: The present invention relates to a catalyst-supporting organic-inorganic hybrid composite particle, and more particularly, to a technique of adjusting a desired pot life and curing speed by preparing a catalyst-supporting organic-inorganic hybrid composite particle by adding a catalyst for polyurethane reaction to a catalyst-supporting particle prepared by stirring an alkoxy silane-functionalized polyurethane precursor and the tetraethyl orthosilicate for a certain period of time and mixing them, and adjusting an initiation rate for polyurethane polymerization through the prepared catalyst-supporting organic-inorganic hybrid composite particle.

Abstract: Provided is a method of manufacturing a secondary battery separator including dissolving a polymer binder in water to prepare an aqueous binder solution, dispersing particles in the aqueous binder solution to prepare an aqueous slurry, and preparing a separator substrate, and applying the aqueous slurry on an upper surface and a lower surface of the separator substrate to form an aqueous slurry coating layer, wherein the separator substrate includes a hydrophobic material, the polymer binder is water-soluble, and the aqueous slurry has a viscosity of about 100 cP to about 6000 cP.

Abstract: A refrigerator includes a main body having a storage compartment formed therein, and a cooling module forming a machine compartment in which a compressor is disposed and detachably mounted to the main body. The cooling module includes a module body forming the machine compartment, a condenser of an L shape disposed on one side of the compressor and including a first part corresponding to a portion of a rear surface of the machine compartment and a second part corresponding to one side of the machine compartment. The condenser is vertically mounted on a base plate disposed below the module body. A module cover is provided to cover the rear of the machine compartment, and a suction flow path includes first and second suction flow paths.

Abstract: Provided is a substrate treating composition. The substrate treating composition includes a first monomer, a second monomer and an acid. The first monomer is represented by Formula 1 and the second monomer is represented by Formula 7. The molecular weight of the solid content of the substrate treating composition including the first monomer, the second monomer and the acid is from about 1,000 g/mol to about 50,000 g/mol.

Abstract: A method for providing contents includes receiving a selection request to view specific contents, from an electronic device; providing a plurality of items corresponding to a plurality of episodes included in the specific contents, in response to the selection request; and performing one of a first process and a second process, related to a provision of the specific episode, according to a product type of the specific episode, in response to a selection of one of the plurality of items through the electronic device.

Abstract: Disclosed are a method for preparing induced pluripotent stem cells from endocardium-derived adult stem cells isolated from peripheral blood and a method for differentiating induced pluripotent stem cells into cardiovascular cells. The endocardium-derived adult stem cells are primary culture cells for preparing induced pluripotent stem cells, can be readily isolated and cultured only with a small amount of peripheral blood, have a high proliferation property so as to be storable without generic variation, and can rapidly ensure a cell number so as to be usable in cell therapy. The endocardium-derived adult stem cells have sternness, thereby having high preparation efficiency, and are derived from the endocardium so as to have the epigenetic memory of cardiovascular cells, thereby having an advantage of being able to be differentiated, after preparing induced pluripotent stem cells, into cardiovascular cells such as endothelial cells, smooth muscle cells and cardiomyocytes with a high efficiency.

Abstract: An air cleaner includes a first air cleaner having an output part, a second air cleaner configured to be electrically connectable to the first air cleaner, a power adapter detachably provided to supply power to the second air cleaner, a first input terminal provided in the second air cleaner and configured to be electrically connected to the output part, a second input terminal provided in the second air cleaner and configured to be electrically connected to the power adapter; and a switch configured to electrically connect the first input terminal to the output part or to electrically connect the second input terminal to the power adapter.