Abstract: A compound of formula (I) wherein R denotes another heterocyclic residue and wherein Ra, Rb, Rc, Rd and Re, are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.

Abstract: The invention relates to compounds of the formula I A-D-C(R1)2—B??(I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

Abstract: A lubricant-tight vane rotary vacuum pump, includes a pump stage (17) having a pump stage housing (10) with a gas inlet, compression chamber (11), and a gas outlet (51), a channel (50) connecting the compression chamber (11) with the gas outlet (51), and a groove (54) at least partially surrounding a mouth of the connecting channel (50) that opens into the gas outlet (51), so that lubricant, which is tossed out of the compression chamber, is collected in the groove (54) and re-entry of the lubricant back into the compression chamber (11) is prevented.

Abstract: The invention relates to a magnetic field sensor comprising a housing which includes a plug and encloses sensor electronics. According to the invention, the housing comprises a two-pieced housing composed of a housing top part, which has a single opening, and a housing base which closes the opening, and out of which the contact pins of the plug extend, and which carries the sensor electronics.

Abstract: The present invention pertains “to the use of a PKC inhibitor in the manufacture of a medicament in the treatment or prevention of diabetic complications, where in the PKC inhibitor is one of 3-(1.H.-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, 3-(1.H.-indol-3-yl)-4-[2-(piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, 3-[3-(4,7-Diaza-spiro [2.5]oct-7-yl)-isoquinolin-1-yl]-4-(7-methyl-1H-indol-3-yl)-pyrrole-2,5-dione or a pharmaceutically acceptable salt thereof.

Abstract: A lubricant-tight vane rotary vacuum pump includes at least one pump stage (17, 18) having a safety valve (3) for controlling gas flow to the pump stage, a lubricant pump, a lubricant reservoir (30) at least partially surrounding the pump stage housing (10, 40), and a hydraulic conduit (31) connecting the lubricant pump outlet (22) with the safety valve (3), with a pressurized lubricant flow through the hydraulic conduit (31) opening the safety valve (3), and a channel (32) branching from the hydraulic conduit (31) for delivering a pressurized lubricant into the lubricant reservoir (30).

Abstract: The invention relates to a linear sensor, comprising a sleeve (5), a pin (7) which comprises a permanent magnet (1) and is linearly displaceably supported in the sleeve (5), and a magnetic field sensor (3) which is fastened to the sleeve (5) and used to detect a displacement of the permanent magnet (1), characterized in that the pin (7) is guided by way of a substantially cylindrical guide (8) and has a magnet or pin holder (6).

Abstract: A compound of formula I wherein R, Ra and Rb are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.

Abstract: A linear sensor is described with a casing (5), with a pin (7) which contains a permanent magnet (1) and which is mounted in the casing (5) in a linearly displaceable manner against the force of a spring (6), and with a magnetic field sensor (3) attached to said casing (5) for detecting of a displacement of the permanent magnet (1). The invention provides that the pin (7) is controlled by a first cylindrical guide (8) and a second cylindrical guide (8).

Abstract: Method of performing condensation reactions, acylations or of preparing heterocycles comprising forming cyclic phosphonic anhydride of the formula (III) by a) reacting phosphonic acid derivatives of formula (I) with acetic anhydride at a temperature ranging between 30 and 150° C. while separating a mixture of ethanoic acid and acetic anhydride by means of distillation, b) then reactively distilling the oligomeric phosphonic acid anhydrides of formula (II) obtained in step a) and transforming the same into the corresponding cyclic trimeric phosphonic acid anhydrides of formula (III), wherein n represents a number between 0 and 300 while R represents allyl, aryl, or open-chain, cyclic, or branched C1 to C8 alkyl radicals, aryloxy, allyloxy, or alkoxy comprising open-chain, cyclic, or branched C1 to C8 alkyl radicals. Preferably the cyclic trimeric phosphonic acid anhydrides formed in step b) are immediately dissolved in an organic solvent that exhibits an inert behavior relative thereto.

Abstract: A compound of formula (I), wherein R, R1, R2, ring A, which ring contains one or two nitrogen atoms, and ring B are as defined in the Specification, pharmaceutical compositions containing these compounds, and uses for these compounds and compositions, in particular, in transplantation.

Abstract: The compounds are indolylmaleimide derivatives comprising either a substituted pyridyl or indolyl residue. The compounds have interesting pharmaceutical properties, e.g. in the treatment and/or prevention of T-cell mediated acute or chronic inflammatory diseases or disorders, autoimmune diseases, or acute or chronic transplant rejection.

Abstract: The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

Abstract: Indolylmaleimide derivatives comprising either a substituted phenyl, naphthyl, tetrahydronaphthyl, quinazolinyl, quinolyl, isoquinolyl or pyrimidinyl residue have interesting pharmaceutical properties, e.g. in the treatment and/or prevention of T-cell mediated acute or chronic inflammatory diseases or disorders, autoimmune diseases, graft rejection or cancer.

Abstract: The present invention relates to a fluid separation device (10) for separating fluid, oil and oil spray from a gas. This fluid separation device (10) comprises a base carrier (21) in which fluid separator elements (20) in the form of flow-through tubes with worm-like segments (23) arranged therein, are integrated. The worm-like segments (23) at the same time form spiral flow paths (25) for the gas. They have a maximal length of half a pitch of the worm-like segment (23) so that the base carrier (21) together with the associated fluid separator elements (20) may be formed as one piece. Several base carriers may be arranged one after the other in a manner such that individual fluid separator elements of various base carriers form a common flow path for the gas.

Abstract: A compound of formula (I) wherein R, R1, and R2, ring A and ring B are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.

Abstract: The invention relates to a locking mechanism for a wind turbine in which a rotor shaft of a drive train is rotatably mounted on a machine support of the wind turbine while the rotor shaft can be connected to a rotor. In order to be able to do maintenance work on the wind turbine, the locking mechanism comprises locking means, especially with a movable locking bolt, which makes it possible to establish a rotationally fixed positive connection between the rotor or the rotor shaft and the machine support. In order to do so, a rotational position of the rotor shaft can automatically be detected in a DESIRED position, and the locking means can be automatically engaged when said DESIRED position has been reached. The disclosed mechanism additionally comprises at least one decelerating device for affecting the drive train, thus allowing the rotational speed of the rotor and the rotor shaft to be reduced.

Abstract: The invention relates to a bearing arrangement, especially for a wind turbine, for transmitting radial and axial forces, two bearing partners being provided that are twistable relative to one another about an axis. The bearing partners each comprise a support area, between which a bearing block is arranged to be insertable in an actuating direction in order to generate a normal force that acts upon the support areas. The bearing block is connected in a rotationally fixed manner to one of the bearing partners. The aim of the invention is to design an improved bearing arrangement which overcomes the drawbacks of the prior art. In particular, the aim is to design a wear-resistant and maintenance-friendly bearing arrangement for an azimuth bearing of a windturbine. Furthermore, an optional aim of the invention is to make it possible to simultaneously use the bearing arrangement as an active brake.