Abstract: An object of the present invention is to provide a method for evaluating a differentiation status of cells using a culture supernatant of stem cells. Provided is “undifferentiation sugar chain marker” composed of the sugar chain structure “Fuc?1-2Gal?1-3GlcNAc” or “Fuc?1-2Gal?1-3GalNAc” and capable of sensitively determining the undifferentiated state of stem cells using a culture supernatant of stem cells. Also found is BC2LCN lectin or a modified product thereof capable of sensitively recognizing the “undifferentiation sugar chain marker” as excellent “probe for detecting the undifferentiation sugar chain marker” capable of determining the undifferentiation status of cells using a culture supernatant.

Abstract: The power supply apparatus includes a transformer, a switch connected to a primary side of the transformer, a first line connected to a secondary side of the transformer to output a voltage of a first polarity, a second line connected to the secondary side of the transformer to output a second polarity voltage whose polarity is opposite to the first polarity, a first diode connected to the first line in a direction, a first capacitor connected to the first line, a second diode connected to the second line in another direction opposite to the direction of the first diode, a second capacitor connected to the second line, a resistor connected to the first line on an output side of the first diode, and a controller controlling a frequency of the switch to control an output from the second line constant.

Abstract: The purpose of the present invention is to develop: a method for selectively separating a glycoprotein derived from the central nervous system from a body fluid or a central nervous system cell; and a method for searching for an index marker for central nervous system diseases, which utilizes the aforementioned method. A protein derived from the central nervous system, which occurs in a trace amount in a body fluid or a central nervous system cell, can be selectively enriched by a two-stage separation procedure comprising removing a glycoprotein having sialic acid at a non-reducing terminal thereof from the body fluid or the central nervous system cell and then separating a glycoprotein having N-acetylglucosamine at a non-reducing terminal thereof.

Abstract: The power supply apparatus includes a transformer having a primary side and a secondary side insulated from each other, a switch element for switching current flowing in the primary side of the transformer, a control part configured to control an operation of the switch element, and two feedback parts configured to detect an output voltage from the transformer so as to output, to the control part, a detection signal in accordance with the output voltage for feedback to the primary side of the transformer.

Abstract: The power supply apparatus includes a switch element for turning ON and OFF supply of electric power to a primary winding of a transformer; a determining unit connected to an auxiliary winding of the transformer, for determining an ON-time of the switch element; and a switching unit for switching the ON-time determined by the determining unit.

Abstract: An incidence angle of laser light with respect to a photosensitive member in a main-scanning direction is different depending on an exposure position. Hence, the spot shape of the laser light on the photosensitive member is different in the main-scanning direction. A filter coefficient is changed in the main-scanning direction, and image data is corrected with the filter coefficient.

Abstract: An image forming apparatus capable of stabilizing image density on a long-term basis by compensating for an error in prediction of toner particle charge amount, while reducing variation in image density on a short-term basis by the prediction. A CPU predicts an amount of electrostatic charge of toner particles in a developer container and sets an exposure condition and causes a toner image to be fixed on a recording medium and a pattern image for detecting image density, to be each formed on a photosensitive drum according to the set exposure condition, while performing gradation correction based on the gradation conversion table. The CPU updates the gradation conversion table such that a detected density of the pattern image becomes closer to a target density. The CPU sets the exposure condition based on a result of the prediction such that toner image density becomes constant.

Abstract: Provided are a method for accurately evaluating the differentiation status of stem cells by selectively staining only stem cells in an undifferentiated state, and a method for positively isolating only stem cells in an undifferentiated state. Specifically provided is a method for determining differentiation of a cell comprising a step of contacting a test cell with a probe comprising protein (A) or (B) below and a step of detecting the presence of binding of the probe to the test cell. The method for determining differentiation of a cell is capable of detecting the presence or absence of an undifferentiated stem cell in test cells by using a probe that specifically reacts with undifferentiated stem cells and detecting the presence of bonding to the test cell.

Abstract: Transmission information indicating transmittance of light of a printing medium used in image formation is acquired, a reduction ratio with respect to a maximum amount of mounted color materials used in the image formation is set based on the transmission information, and a fixing index indicating a fixing state of the color materials with respect to the printing medium is set based on the transmission information.

Abstract: An object of the present invention is to provide a method for introducing a target substance into undifferentiated cells, and a carrier therefor, whereby the target substance can be specifically introduced into the undifferentiated cells by contacting the undifferentiated cells with an rBC2LCN-target substance fusion product in which rBC2LCN lectin is fused to the target substance. Particularly, an rBC2LCN-toxin fusion product in which rBC2LCN lectin is fused to a toxin functioning in cells or its domain having the ability to kill cells functions as an agent for eliminating undifferentiated stem cells and can be administered into a medium after inducing the differentiation of the stem cells to reliably kill only the stem cells in an undifferentiated state.

Abstract: A measurement apparatus comprises a light source of line shape configured to move in a predetermined direction and illuminate a measurement target object, and a capturing unit configured to capture the measurement target object illuminated by the light source of line shape. The measurement apparatus controls the light source of line shape and the capturing unit, and estimates the reflection characteristics of the measurement target object from a plurality of images captured by the capturing unit.

Abstract: A device for controlling an image forming apparatus includes an acquisition unit configured to acquire image data, and pixel piece insertion/extraction information indicating whether a pixel piece needs to be inserted into or extracted from each pixel of the image data, a generation unit configured to generate an exposure signal according to a pixel value indicating a pixel of interest in the image data and to pixel piece insertion/extraction information on the pixel of interest, and a control unit configured to control exposure by the apparatus according to the exposure signal. The generation unit causes the pixel of interest to be formed by a plurality of pixel pieces arranged in a direction in which the apparatus scans, presets at least one of the pixel pieces as an adjustment blank pixel piece, and deletes the piece when the width of the pixel of interest in the scanning direction is reduced.

Abstract: An object of the present invention is to provide a method for evaluating a differentiation status of cells using a culture supernatant of stem cells. Provided is “undifferentiation sugar chain marker” composed of the sugar chain structure “Fuc?1-2Gal?1-3GlcNAc” or “Fuc?1-2Gal?1-3GalNAc” and capable of sensitively determining the undifferentiated state of stem cells using a culture supernatant of stem cells. Also found is BC2LCN lectin or a modified product thereof capable of sensitively recognizing the “undifferentiation sugar chain marker” as excellent “probe for detecting the undifferentiation sugar chain marker” capable of determining the undifferentiation status of cells using a culture supernatant.

Abstract: This invention is to provide a technique of always obtaining a stable output image in image formation using toner. A supplier (1217) supplies toner in a decided toner supply amount. A developing device (1206) agitates the supplied toner and supplies the agitated toner to an electrostatic latent image formed on a photosensitive drum (1203), thereby developing a toner image on the photosensitive drum (1203). A correction amount calculation unit (1106) estimates the toner charge amount by calculating a function model that approximates the variation characteristic of the toner charge amount using the toner consumption necessary for printing a print target image, the toner supply amount necessary for printing the print target image, and the toner agitation time. At least one of an image processing condition and a process condition is controlled using the estimated toner charge amount.

Abstract: An image forming apparatus capable of making image quality more stable than in the prior art. An electrostatic latent image is formed on the surface of a photosensitive member based on an image signal. A developing device develops the electrostatic latent image on the photosensitive member by toner to thereby form a patch image. An optical sensor detects the density of the patch image. A toner charge amount is calculated from the density detected by the optical sensor, and a change in the toner charge amount is predicted based on a plurality of results of the calculation of the toner charge amount. The image forming apparatus generates a ?LUT for use in correcting the relationship between the image signal and the density based on the predicted change in the toner charge amount.

Abstract: Provided are a method for accurately evaluating the differentiation status of stem cells by selectively staining only stem cells in an undifferentiated state, and a method for positively isolating only stem cells in an undifferentiated state. Specifically provided is a method for determining differentiation of a cell comprising a step of contacting a test cell with a probe comprising protein (A) or (B) below and a step of detecting the presence of binding of the probe to the test cell. The method for determining differentiation of a cell is capable of detecting the presence or absence of an undifferentiated stem cell in test cells by using a probe that specifically reacts with undifferentiated stem cells and detecting the presence of bonding to the test cell.

Abstract: A measurement apparatus comprises a light source of line shape configured to move in a predetermined direction and illuminate a measurement target object, and a capturing unit configured to capture the measurement target object illuminated by the light source of line shape. The measurement apparatus controls the light source of line shape and the capturing unit, and estimates the reflection characteristics of the measurement target object from a plurality of images captured by the capturing unit.

Abstract: The purpose of the present invention is to develop: a method for selectively separating a glycoprotein derived from the central nervous system from a body fluid or a central nervous system cell; and a method for searching for an index marker for central nervous system diseases, which utilizes the aforementioned method. A protein derived from the central nervous system, which occurs in a trace amount in a body fluid or a central nervous system cell, can be selectively enriched by a two-stage separation procedure comprising removing a glycoprotein having sialic acid at a non-reducing terminal thereof from the body fluid or the central nervous system cell and then separating a glycoprotein having N-acetylglucosamine at a non-reducing terminal thereof.

Abstract: The power supply apparatus includes a transformer having a primary side and a secondary side insulated from each other, a switch element for switching current flowing in the primary side of the transformer, a control part configured to control an operation of the switch element, and two feedback parts configured to detect an output voltage from the transformer so as to output, to the control part, a detection signal in accordance with the output voltage for feedback to the primary side of the transformer.

Abstract: A device for controlling an image forming apparatus includes an acquisition unit configured to acquire image data, and pixel piece insertion/extraction information indicating whether a pixel piece needs to be inserted into or extracted from each pixel of the image data, a generation unit configured to generate an exposure signal according to a pixel value indicating a pixel of interest in the image data and to pixel piece insertion/extraction information on the pixel of interest, and a control unit configured to control exposure by the apparatus according to the exposure signal. The generation unit causes the pixel of interest to be formed by a plurality of pixel pieces arranged in a direction in which the apparatus scans, presets at least one of the pixel pieces as an adjustment blank pixel piece, and deletes the piece when the width of the pixel of interest in the scanning direction is reduced.