Patents by Inventor Kai Tian

Kai Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOUCH DETECTING STRUCTURE, TOUCH DISPLAY DEVICE AND TOUCH DETECTING AND MANUFACTURING METHODS
    Publication number: 20150108434
    Abstract: The invention discloses a touch detecting structure, an organic light emitting touch display device, a method of detecting a touch on a device and a method of manufacturing a device. The touch detecting structure includes: a first signal transmission line arranged on a first substrate of an organic light emitting touch display device; an insulating layer arranged on the first signal transmission line and having a via hole and a protrusion; a second signal transmission line located on the insulating layer and passing the top of the protrusion; a signal transmission terminal arranged on the lateral surface of the protrusion and having one end connected with the first signal transmission line through the via hole and the other end located on the top of the protrusion, and insulated from the second signal transmission line; and a cathode film arranged on a second substrate.
    Type: Application
    Filed: March 21, 2014
    Publication date: April 23, 2015
    Applicants: Tianma Micro-Electronics Co., Ltd., Shanghai Tianma Micro-Electronics Co., Ltd.
    Inventors: Kai TIAN, Yujun Li
  • NANOPORE-FACILITATED SINGLE MOLECULE DETECTION OF NUCLEIC ACID
    Publication number: 20130220809
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Application
    Filed: July 14, 2011
    Publication date: August 29, 2013
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Inhibitors of tace
    Patent number: 7919520
    Abstract: The present invention relates to compounds that inhibit TACE, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: April 5, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Upul Bandarage, Jon Come, Emanuele Perola, Govinda Rao Bhisetti, Jeffrey O. Saunders, Shi Kai Tian, Tiansheng Wang
  • Diaminotriazoles useful as inhibitors of protein kinases
    Patent number: 7902239
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: March 8, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Albert C. Pierce, Michael Arnost, Robert J. Davies, Cornelia J. Forster, Vincent Galullo, Ronald Grey, Jr., Mark Ledeboer, Shi-Kai Tian, Jinwang Xu, Hayley Binch, Brian Ledford, David Messersmith, Suganthi Nanthakumar, Andrew Jayaraj, Greg Henkel, Francesco G. Salituro, Jian Wang
  • INHIBITORS OF TACE
    Publication number: 20090176782
    Abstract: The present invention relates to compounds that inhibit TACE, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Application
    Filed: November 12, 2008
    Publication date: July 9, 2009
    Inventors: Upul Bandarage, Jon Come, Emanuele Perola, Govinda Rao Bhisetti, Jeffrey O. Saunders, Shi Kai Tian, Tiansheng Wang
  • Inhibitors of TACE
    Patent number: 7485664
    Abstract: The present invention relates to compounds that inhibit TACE, compositions thereof, and methods of using those compounds and compositions for treating diseases.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: February 3, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Upul Bandarage, Jon H. Come, Emanuele Perola, Govinda Rao Bhisetti, Jeffrey O. Saunders, Tiansheng Wang, Shi-Kai Tian
  • DIAMINOTRIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES
    Publication number: 20080014189
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: July 9, 2007
    Publication date: January 17, 2008
    Inventors: Albert Pierce, Michael Arnost, Robert Davies, Cornelia Forster, Vincent Galullo, Ronald Gray, Mark Ledeboer, Shi-Kai Tian, Jinwang Xu, Hayley Binch, Brian Ledford, David Messersmith, Suganthi Nanthakumar, Andrew Jayaraj, Greg Henkel, Francesco Salituro, Jian Wang
  • Diaminotriazoles useful as inhibitors of protein kinases
    Patent number: 7279469
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: October 9, 2007
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Albert C. Pierce, Michael Amost, Robert J. Davies, Cornelia J. Forster, Vincent Galullo, Ronald Grey, Jr., Mark Ledeboer, Shi-Kai Tian, Jinwang Xu, Hayley Binch, Brian Ledford, David Messersmith, Suganthi Nanthakumar, Andrew Jayaraj, Greg Henkel, Francesco G. Salituro, Jian Wang
  • Catalytic asymmetric cyanosilylation of ketones, aldehydes, thioketones, thioaldehydes, imines and hydrazones
    Patent number: 7078547
    Abstract: One aspect of the present invention relates to a method for the catalytic asymmetric cyanosilylation of ketones, aldehydes, thioketones, thioaldehydes, imines and hydrazones. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a substrate selected from the group consisting of ketones, aldehydes, thioketones, thioaldehydes, imines and hydrazones; and a silyl cyanide, e.g., trimethylsilyl cyanide. In preferred embodiments, the substrate is a ketone or aldehyde. A preferred embodiment of the present invention relates to practicing the method in a halocarbon solvent, e.g., chloroform. Another preferred embodiment of the present invention relates to practicing the method in an ester solvent, e.g., ethyl acetate. In certain embodiments, the methods of the present invention produce a silyl cyanohydrin with an enantiomeric excess greater than about 80%.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: July 18, 2006
    Assignee: Brandeis University
    Inventors: Li Deng, Shi-Kai Tian
  • Diaminotriazoles useful as inhibitors of protein kinases
    Publication number: 20040214817
    Abstract: The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 17, 2003
    Publication date: October 28, 2004
    Inventors: Albert C. Pierce, Michael Amost, Robert J. Davies, Cornelia J. Forster, Vincent Galullo, Ronald Grey, Mark Ledeboer, Shi-Kai Tian, Jinwang Xu, Hayley Binch, Brian Ledford, David Messersmith, Suganthi Nanthakumar, Andrew Jayaraj, Greg Henkel, Francesco G. Salituro, Jian Wang
  • Catalytic asymmetric cyanosilylation of ketones, aldehydes, thioketones, thioaldehydes, imines and hydrazones
    Publication number: 20030236226
    Abstract: One aspect of the present invention relates to a method for the catalytic asymmetric cyanosilylation of ketones, aldehydes, thioketones, thioaldehydes, imines and hydrazones. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a substrate selected from the group consisting of ketones, aldehydes, thioketones, thioaldehydes, imines and hydrazones; and a silyl cyanide, e.g., trimethylsilyl cyanide. In preferred embodiments, the substrate is a ketone or aldehyde. A preferred embodiment of the present invention relates to practicing the method in a halocarbon solvent, e.g., chloroform. Another preferred embodiment of the present invention relates to practicing the method in an ester solvent, e.g., ethyl acetate. In certain embodiments, the methods of the present invention produce a silyl cyanohydrin with an enantiomeric excess greater than about 80%.
    Type: Application
    Filed: February 5, 2003
    Publication date: December 25, 2003
    Inventors: Li Deng, Shi-Kai Tian