Patents by Inventor Karl Guegler

Karl Guegler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 7029894
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: April 18, 2006
    Assignee: Applera Corporation
    Inventors: Karl Guegler, Ellen M. Beasley, Valentina Di Francesco
  • Human cathepsin
    Publication number: 20060063249
    Abstract: The invention provides a new human cathepsin (LCAP) and polynucleotides which identify and encode LCAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of LCAP.
    Type: Application
    Filed: September 12, 2003
    Publication date: March 23, 2006
    Applicant: Incyte Corporation
    Inventors: Olga Bandman, Karl Guegler, Neil Corley, Purvi Shah
  • Human protease molecules
    Publication number: 20050282214
    Abstract: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
    Type: Application
    Filed: July 19, 2005
    Publication date: December 22, 2005
    Inventors: Olga Bandman, Jennifer Hillman, Henry Yue, Karl Guegler, Neil Corley, Y. Tang, Purvi Shah
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6942983
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: July 8, 2004
    Date of Patent: September 13, 2005
    Assignee: Applera Corporation
    Inventors: Jiayin Li, Karl Guegler, Ellen M. Beasley, Karen A. Ketchum, Valentina Di Francesco
  • Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
    Publication number: 20050186613
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
    Type: Application
    Filed: March 21, 2005
    Publication date: August 25, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Gennady Merkulov, Karl Guegler, Rhonda Brandon, Karen Ketchum, Valentina Francesco, Ellen Beasley
  • Human protease molecules
    Publication number: 20050181404
    Abstract: The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUPM.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 18, 2005
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer Hillman, Henry Yue, Karl Guegler, Neil Corley, Y. Tang, Purvi Shah
  • Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
    Publication number: 20050165219
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
    Type: Application
    Filed: January 12, 2005
    Publication date: July 28, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Gennady Merkulov, Karl Guegler, Marion Webster, Karen Ketchum, Valentina Di Francesco, Ellen Beasley
  • Signal peptide-containing molecules
    Publication number: 20050155089
    Abstract: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
    Type: Application
    Filed: April 7, 2004
    Publication date: July 14, 2005
    Applicant: Incyte Corporation
    Inventors: Preeti Lal, Y. Tang, Gina Gorgone, Neil Corley, Karl Guegler, Mariah Baughn, Ingrid Akerblom, Janice Au-Young, Henry Yue, Chandra Patterson, Roopa Reddy, Jennifer Hillman, Olga Bandman
  • Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
    Publication number: 20050154197
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
    Type: Application
    Filed: November 23, 2004
    Publication date: July 14, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Gennady Merkulov, Karl Guegler, Rhonda Brandon, Valentina Di Francesco, Ellen Beasley
  • Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
    Publication number: 20050148013
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
    Type: Application
    Filed: February 22, 2005
    Publication date: July 7, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Karl Guegler, Karen Ketchum, Valentina Di Francesco, Ellen Beasley
  • Protein-transport-associated molecules
    Publication number: 20050130204
    Abstract: The invention provides human protein transport molecules (PTAM) and polynucleotides which identify and encode PTAM. The Invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of PTAM.
    Type: Application
    Filed: November 15, 2004
    Publication date: June 16, 2005
    Inventors: Y. Tang, Preeti Lal, Olga Bandman, Henry Yue, Neil Corley, Karl Guegler, Gina Gorgone, Mariah Baughn, Chandra Patterson
  • Isolated human transporter proteins, nucleic acid molecules encoding human, transporter proteins, and uses thereof
    Publication number: 20050112681
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
    Type: Application
    Filed: December 29, 2004
    Publication date: May 26, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Ming-Hui Wei, Kabir Chaturvedi, Karl Guegler, Marion Webster, Karen Ketchum, Valentina Di Francesco, Ellen Beasley
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Publication number: 20050106622
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Application
    Filed: December 29, 2004
    Publication date: May 19, 2005
    Applicant: APPLERA CORPORATION
    Inventors: Ming-Hui Wei, Karl Guegler, Karen Ketchum, Gennady Merkulov, Trevor Woodage, Valentina Di Francesco, Ellen Beasley
  • Neurotransmission associated proteins
    Publication number: 20050106672
    Abstract: The invention provides human neurotransmission associated proteins (NTAP) and polynucleotides which identify and encode NTAP. The invention also provides expression vectors, host cells, antibodies, antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NTAP.
    Type: Application
    Filed: November 29, 2004
    Publication date: May 19, 2005
    Inventors: Preeti Lal, Y. Tang, Henry Yue, Neil Corley, Karl Guegler, Gina Gorgone, Mariah Baughn, Chandra Patterson
  • Human regulatory proteins
    Publication number: 20050084936
    Abstract: The invention provides human regulatory proteins collectively designated HRGP, and polynucleotides which identify and encode these molecules. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, treating, and preventing disorders associated with expression of human regulatory proteins.
    Type: Application
    Filed: October 18, 2004
    Publication date: April 21, 2005
    Inventors: Preeti Lal, Olga Bandman, Jennifer Hillman, Janice Au-Young, Y. Tang, Henry Yue, Purvi Shah, Karl Guegler, Neil Corley
  • Human receptor molecules
    Publication number: 20050079575
    Abstract: The invention provides human receptor molecules (REC) and polynucleotides which identify and encode REC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of REC.
    Type: Application
    Filed: June 21, 2004
    Publication date: April 14, 2005
    Inventors: Jennifer Hillman, Olga Bandman, Y. Tang, Henry Yue, Preeti Lal, Neil Corley, Karl Guegler, Chandra Patterson
  • Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
    Patent number: 6875597
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: April 5, 2005
    Assignee: Applera Corporation
    Inventors: Karl Guegler, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
  • Oxidoreductase molecules
    Publication number: 20050053987
    Abstract: The invention provides human oxidoreductase molecules (OXRE) and polynucleotides which identify and encode OXRE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of OXRE.
    Type: Application
    Filed: July 20, 2004
    Publication date: March 10, 2005
    Inventors: Preeti Lal, Karl Guegler, Gina Gorgone, Neil Corley, Mariah Baughn, Y. Tang, Jennifer Hillman, Olga Bandman, Yalda Azimzai, Janice Au-Young, Henry Yue, Dyung Lu, Junming Yang
  • Human epidermal proteins HEP1-1 to HEP1-6
    Publication number: 20050048612
    Abstract: The invention provides human epidermal proteins (HEP1) and polynucleotides which identify and encode HEP1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HEP1.
    Type: Application
    Filed: July 6, 2004
    Publication date: March 3, 2005
    Inventors: Y. Tang, Preeti Lal, Neil Corley, Karl Guegler, Chandra Patterson, Mariah Baughn, Henry Yue
  • Human SCAD family molecules
    Publication number: 20050032098
    Abstract: The invention provides human SCAD family molecules (HSFM) and polynucleotides which identify and encode HSFM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSFM.
    Type: Application
    Filed: June 21, 2004
    Publication date: February 10, 2005
    Inventors: Preeti Lal, Karl Guegler, Gina Gorgone, Neil Corley, Mariah Baughn, Henry Yue