Patents by Inventor Karl J. Guegler

Karl J. Guegler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human ankyrin family protein
    Patent number: 5989863
    Abstract: The invention provides a human ankyrin family protein (ANFP) and polynucleotides which identify and encode ANFP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of ANFP.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Karl J. Guegler, Neil C. Corley, Henry Yue
  • Human ion transport-like protein
    Patent number: 5989861
    Abstract: The invention provides a human ion transport-like protein (HITLP) and polynucleotides which identify and encode HITLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HITLP.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • ATP synthase subunit homolog
    Patent number: 5989822
    Abstract: The invention provides a human ATP synthase subunit homolog (ASYNT) and polynucleotides which identify and encode ASYNT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of ASYNT.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Antibodies which specifically bind to human tumor-associated Kazal inhibitor-like polypeptide
    Patent number: 5986064
    Abstract: The present invention provides a human tumor-associated Kazal inhibitor (HuKI) and polynucleotides which identify and encode HuKI. The invention also provides expression vectors, host cells, antibodies and antagonists. The invention also provides methods for the prevention and treatment of diseases associated with expression of HuKI, as well as diagnostic assays.
    Type: Grant
    Filed: December 3, 1998
    Date of Patent: November 16, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Purvi Shah
  • Human aflatoxin B1 aldehyde reductase
    Patent number: 5981244
    Abstract: The invention provides a human aflatoxin B1 aldehyde reductase (AFB1-hAR) and polynucleotides which identify and encode AFB1-hAR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of AFB1-hAR.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: November 9, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Purvi Shah, Karl J. Guegler, Neil C. Corley
  • NADH dehydrogenase PDSW subunit
    Patent number: 5976804
    Abstract: The invention provides a human NADH dehydrogenase subunit (HND-1) and polynucleotides which identify and encode HND-1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HND-1.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: November 2, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler
  • Human importin alpha homolog
    Patent number: 5965394
    Abstract: The invention provides a human importin alpha homolog (IMPAH) and polynucleotides which identify and encode IMPAH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of IMPAH.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • Serine/threonine protein kinase
    Patent number: 5965365
    Abstract: The present invention provides a human growth factor receptor binding protein (HSTPK) and polynucleotides which encode HSTPK. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for producing HSTPK and for treating disorders associated with expression of HSTPK.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal
  • Protein kinase molecules
    Patent number: 5962232
    Abstract: The invention provides human protein kinase molecules (HPKM) and polynucleotides which identify and encode HPKM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKM.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Preeti Lal, Ingrid E. Akerblom, Purvi Shah, Neil C. Corley, Karl J. Guegler
  • Human DP1 homolog
    Patent number: 5958725
    Abstract: The invention provides a human DPl homolog (DPlh)) and polynucleotides which identify and encode DPlh. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of DPlh.
    Type: Grant
    Filed: May 29, 1997
    Date of Patent: September 28, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Purvi Shah, Joanne R. Petithory, Neil C. Corley
  • Human galactosyltransferases
    Patent number: 5955282
    Abstract: The invention provides human galactosyltransferases (HUGA) and polynucleotides which identify and encode HUGA. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HUGA.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: September 21, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Purvi Shah, Chandra Patterson
  • Human chemokine receptor-like protein
    Patent number: 5955303
    Abstract: The present invention provides a human chemokine receptor-like, protein (NHCR) and polynucleotides which identify and encode NHCR. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of NHCR.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: September 21, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Janice Au-Young, Karl J. Guegler, Muzong Cheng
  • Human growth-related CDC10 homolog
    Patent number: 5952214
    Abstract: The invention provides a human growth-related CDC10 homolog (GR-SEP) and polynucleotides which identify and encode GR-SEP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of GR-SEP.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: September 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Matthew R. Kaser, Preete Mathur
  • Human zygin-1
    Patent number: 5948619
    Abstract: The invention provides a human zygin-1 (ZY-1H) and polynucleotides which identify and encode ZY-1H. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ZY-1H.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: September 7, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Neil C. Corley, Karl J. Guegler, Purvi Shah
  • Ras protein
    Patent number: 5945306
    Abstract: The invention provides two human Ras proteins, referred to collectively as "RAPR" and individually as "RAPR-1" and "RAPR-2", and polynucleotides which identify and encode RAPR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of RAPR.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: August 31, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Karl J. Guegler, Y. Tom Tang, Neil C. Corley
  • Human regulatory molecules
    Patent number: 5932442
    Abstract: The invention provides human regulatory molecules and polynucleotides (collectively designated HRM) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, preventing, and treating disorders associated with expression of human regulatory molecules.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: August 3, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Olga Bandman, Purvi Shah, Janice Au-Young, Henry Yue, Karl J. Guegler, Neil C. Corley
  • Nek1-related protein kinase
    Patent number: 5928874
    Abstract: The invention provides a human Nek1-related protein kinase (NRPK) and polynucleotides which identify and encode NRPK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NRPK.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: July 27, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Neil C. Corley, Karl J. Guegler, Mariah Baughn
  • Human aflatoxin B1 aldehyde reductase
    Patent number: 5919685
    Abstract: The invention provides a human aflatoxin B1 aldehyde reductase (AFB1-hAR) and polynucleotides which identify and encode AFB1-hAR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of AFB1-hAR.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: July 6, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Purvi Shah, Karl J. Guegler, Neil C. Corley
  • Polynucleotides encoding cytokine inducible regulatory protein
    Patent number: 5919661
    Abstract: The invention provides a human cytokine inducible regulatory protein (CIRP-1) and polynucleotides which identify and encode CIRP-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of CIRP-1.
    Type: Grant
    Filed: August 25, 1997
    Date of Patent: July 6, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • NADH dehydrogenase subunits
    Patent number: 5919686
    Abstract: The invention provides two human NADH dehydrogenase subunits (HNDS) and polynucleotides which identify and encode HNDS. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HNDS.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: July 6, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Karl J. Guegler, Purvi Shah