Patents by Inventor Karl J. Guegler

Karl J. Guegler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calcium binding protein
    Patent number: 6365371
    Abstract: The invention provides a human calcium binding protein (hCBP) and polynucleotides which identify and encode hCBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of hCBP.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: April 2, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Y. Tom Tang, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone
  • Human extracellular matrix proteins
    Publication number: 20020038006
    Abstract: The invention provides two human extracellular matrix proteins (ECMP) and polynucleotides which identify and encode ECMP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ECMP.
    Type: Application
    Filed: April 16, 2001
    Publication date: March 28, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Neil C. Corley, Karl J. Guegler
  • Cell surface glycoproteins
    Patent number: 6358923
    Abstract: The invention provides human cell surface glycoproteins (CSGP) and polynucleotides which identify and encode CSGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CSGP.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: March 19, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Henry Yue, Neil C. Corley, Karl J. Guegler, Gina A. Gorgone, Mariah R. Baughn
  • Antibody to human testin and methods of making and using
    Patent number: 6358711
    Abstract: The invention provides a human testin (HTES) and polynucleotides which identify and encode HTES. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HTES.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: March 19, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • GPCR diagnostic for brain cancer
    Publication number: 20020025555
    Abstract: The invention provides a cDNA which encodes chemokine receptor-like protein. It also provides for the use of the cDNA, protein, and antibodies in the diagnosis, prognosis, treatment and evaluation of therapies for infection, inflammation and cancer, particularly meningioma of the brain. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
    Type: Application
    Filed: May 3, 2001
    Publication date: February 28, 2002
    Inventors: Janice Au-Young, Karl J. Guegler, Muzong Cheng
  • SH3-containing proteins
    Patent number: 6326158
    Abstract: The invention provides a human SH3-containing protein (HS3C) and polynucleotides which identify and encode HS3C. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HS3C.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: December 4, 2001
    Assignee: Incyte Genomics Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal
  • Human extracellular matrix proteins
    Patent number: 6303765
    Abstract: The invention provides two human extracellular matrix proteins (ECMP) and polynucleotides which identify and encode ECMP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ECMP.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: October 16, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Neil C. Corley, Karl J. Guegler
  • Human membrane-spanning proteins
    Publication number: 20010025098
    Abstract: The invention provides a human membrane spanning proteins (MSPs) and polynucleotides which identify and encode MSPs. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of MSPs.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 27, 2001
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Olga Bandman, Preeti Lal, Jennifer L. Hillman, Henry Yue, Neil C. Corley, Karl J. Guegler, Matthew R. Kaser, Mariah R. Baughn, Purvi Shah
  • Nucleic acids encoding human ubiquitin-conjugating enzyme homologs
    Patent number: 6277568
    Abstract: The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: August 21, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Mariah Baughn, Yalda Azimzai
  • Serine dehydratase homolog
    Patent number: 6277619
    Abstract: The invention provides a human serine dehydratase homolog (SDHH) and polynucleotides which identify and encode SDHH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of SDHH.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: August 21, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Extracellular adhesive proteins
    Publication number: 20010010913
    Abstract: The invention provides human extracellular adhesive proteins (EXADH) and polynucleotides which identify and encode EXADH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of EXADH.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 2, 2001
    Applicant: Incyte Pharmaceuticals, Inc
    Inventors: Jennifer L. Hillman, Henry Yue, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Human goose-type lysozyme
    Patent number: 6268164
    Abstract: The invention provides a human goose-type lysozyme (GOLY) and polynucleotides which identify and encode GOLY. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GOLY.
    Type: Grant
    Filed: February 23, 2000
    Date of Patent: July 31, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson
  • Protein kinase homologs
    Patent number: 6264947
    Abstract: The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: July 24, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone, Yalda Azimzai, Dyung Aina M. Lu
  • Prostate associated Ets protein
    Patent number: 6265565
    Abstract: The invention provides a human prostate associated Ets protein (PRAEP) and polynucleotides which identify and encode PRAEP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PRAEP.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: July 24, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal, Neil C. Corley
  • Kinesin-like motor protein
    Patent number: 6248594
    Abstract: The invention provides a human kinesin-like motor protein (KLIMP) and polynucleotides which identify and encode KLIMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KLIMP.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: June 19, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Human GTPase-associated proteins
    Patent number: 6242214
    Abstract: The invention provides human GTPase-associated proteins (GPAP) and polynucleotides which identify and encode GPAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GPAP.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: June 5, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson
  • Human protein kinases
    Patent number: 6232077
    Abstract: The present invention provides novel human protein kinases (HPK) and polynucleotides which identify and encode HPK. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPK. The invention also provides for pharmaceutical compositions comprising HPK or antagonists of HPK, and antibodies which specifically bind HPK. Additionally, the invention provides antisense molecules to HPK for treatment or prevention of diseases associated with abnormal expression of HPK.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: May 15, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Janice Au-Young, Karl J. Guegler, Phillip R. Hawkins
  • Human proteinase molecules
    Patent number: 6232454
    Abstract: The invention provides human proteinase molecules (HPRM) and polynucleotides which identify and encode HPRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPRM.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: May 15, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Growth-associated protease inhibitor heavy chain precursor
    Patent number: 6228991
    Abstract: The invention provides a human growth-associated protease inhibitor heavy chain precursor (GAPIP) and polynucleotides which identify and encode GAPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GAPIP.
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: May 8, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Chandra Patterson
  • Human protein kinase C inhibitor
    Patent number: 6218113
    Abstract: The invention provides a human protein kinase C inhibitor (HPKCI) and polynucleotides which identify and encode HPKCI. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKCI.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: April 17, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Henry Yue, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley