Patents by Inventor Karl J. Guegler

Karl J. Guegler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ATP synthase subunit homolog
    Patent number: 6036954
    Abstract: The invention provides a human ATP synthase subunit homolog (ASYNT) and polynucleotides which identify and encode ASYNT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of ASYNT.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: March 14, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Human cathepsin
    Patent number: 6033893
    Abstract: The invention provides a new human cathepsin (LCAP) and polynucleotides which identify and encode LCAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of LCAP.
    Type: Grant
    Filed: June 26, 1997
    Date of Patent: March 7, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • Nek1-related protein kinase
    Patent number: 6030801
    Abstract: The invention provides a human Nek 1-related protein kinase (NRPK) and polynucleotides which identify and encode NRPK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NRPK.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: February 29, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Neil C. Corley, Karl J. Guegler, Mariah Baughn
  • Cyclophilin-type peptidyl-prolyl cis/trans isomerase
    Patent number: 6030825
    Abstract: The invention provides a human cyclophilin-type peptidyl-prolyl cis/trans isomerase (CPCI) and polynucleotides which identify and encode CPCI. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of CPCI.
    Type: Grant
    Filed: August 19, 1998
    Date of Patent: February 29, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Human RNA binding proteins
    Patent number: 6020164
    Abstract: The invention provides human RNA binding proteins (RNABP) and polynucleotides which identify and encode RNABP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of RNABP.
    Type: Grant
    Filed: October 21, 1998
    Date of Patent: February 1, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Dyung Aina M. Lu, Mariah R. Baughn
  • Cytikine signal regulators
    Patent number: 6020165
    Abstract: The invention provides human cytokine signal regulators (CKSR) and polynucleotides which identify and encode CKSR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CKSR.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: February 1, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Kinesin-like motor protein
    Patent number: 6013454
    Abstract: The invention provides a human kinesin-like motor protein (KLIMP) and polynucleotides which identify and encode KLIMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KLIMP.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: January 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Protein kinase homologs
    Patent number: 6013455
    Abstract: The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: January 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Yang, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone, Yalda Azimzai, Dyung Aina M. Lu
  • RAB protein
    Patent number: 6010859
    Abstract: The present invention provides a human novel RAB protein (SRAB) and polynucleotides which identify and encode SRAB. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of SRAB.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: January 4, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler
  • Polynucleotide encoding a novel purinergic P.sub.2U receptor
    Patent number: 6008039
    Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel purinergic P.sub.U2 receptor (PNR) expressed in human placenta. The present invention also provides for antisense molecules to the nucleotide sequences which encode PNR, expression vectors for the production of purified PNR, antibodies capable of binding specifically to PNR, hybridization probes or oligonucleotides for the detection of PNR-encoding nucleotide sequences, genetically engineered host cells for the expression of PNR, and diagnostic tests based on PNR-encoding nucleic acid molecules or antibodies produced against the polypeptide PNR.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: December 28, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Roger Coleman, Janice Au-Young, Susan G. Stuart, Karl J. Guegler
  • Cell cycle related proteins
    Patent number: 6008337
    Abstract: The invention provides human cell cycle related proteins (CCRP) and polynucleotides which identify and encode CCRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of CCRP.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: December 28, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Henry Yue, Preeti Lal
  • Human S1-5 ECMP-like protein
    Patent number: 6004753
    Abstract: The invention provides a human S1-5 ECMP-like protein (SELP) and polynucleotides which identify and encode SELP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of SELP.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: December 21, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Karl J. Guegler, Purvi Shah
  • Growth-associated protease inhibitor heavy chain precursor
    Patent number: 6001596
    Abstract: The invention provides a human growth-associated protease inhibitor heavy chain precursor (GAPIP) and polynucleotides which identify and encode GAPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GAPIP.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: December 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Chandra Patterson
  • Human growth-associated methyltransfeases
    Patent number: 6001607
    Abstract: The invention provides a human growth-associated methyltransferase (GAMT) and polynucleotides which identify and encode GAMT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GAMT.
    Type: Grant
    Filed: April 13, 1998
    Date of Patent: December 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Henry Yue, Karl J. Guegler, Purvi Shah
  • Human lysophosphatidic acid acyltransferase
    Patent number: 6001620
    Abstract: The invention provides a human lysophosphatidic acid acyltranferase (HLPAAT) and polynucleotides which identify and encode HLPAAT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HLPAAT.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: December 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley
  • Human testin
    Patent number: 6001594
    Abstract: The invention provides a human testin (HTES) and polynucleotides which identify and encode HTES. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HTES.
    Type: Grant
    Filed: December 31, 1997
    Date of Patent: December 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley
  • Polynucleotide encoding human G-protein coupled receptor
    Patent number: 5994097
    Abstract: The invention provides a human G-protein coupled receptor (GRecH) and polynucleotides which identify and encode GRecH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRecH.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: November 30, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Purvi Shah, Neil C. Corley
  • Human isomerase homologs
    Patent number: 5989860
    Abstract: The invention provides human isomerase homologs (HIH) and polynucleotides which identify and encode HIH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HIH.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • Vesicle trafficking proteins
    Patent number: 5989859
    Abstract: The invention provides three human vesicle trafficking proteins (VTP) and polynucleotides which identify and encode VTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of VTP.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Karl J. Guegler, Purvi Shah, Neil C. Corley
  • Human ena/VASP-like protein splice variant
    Patent number: 5990087
    Abstract: The invention provides a human ena/VASP-like protein splice variant (EVL1) and polynucleotides which identify and encode EVL1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of EVL1.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: November 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley