Patents by Inventor Kazumichi Imai

Kazumichi Imai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060086612
    Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary disposed at the pitch of wells on the side of sample plate (within the area of the wells) into electrical contact with a common electrode, the capillaries and electrodes are made integral in construction. When a voltage is applied to the electrophoretic instrument via a common electrode portion, the voltage is applied to the electrodes for each capillary. This enables an inexpensive microtiter plate, etc. to be used and a multiple of capillaries to be simultaneously inserted, attached and detached.
    Type: Application
    Filed: December 8, 2005
    Publication date: April 27, 2006
    Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
  • Patent number: 7014746
    Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary disposed at the pitch of wells on the side of sample plate (within the area of the wells) into electrical contact with a common electrode, the capillaries and electrodes are made integral in construction. When a voltage is applied to the electrophoretic instrument via a common electrode portion, the voltage is applied to the electrodes for each capillary. This enables an inexpensive microtiter plate, etc. to be used and a multiple of capillaries to be simultaneously inserted, attached and detached.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: March 21, 2006
    Assignee: Hitachi, Ltd.
    Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
  • Publication number: 20060006066
    Abstract: Analysis is performed efficiently in an electrophoresis apparatus while avoiding deterioration of samples. A plurality of sample plates are stored in frozen storage. When a particular sample plate is being analyzed, other sample plates are stored in a standby unit. In this way, a plurality of sample plates can be stored under cool conditions and analysis can be performed efficiently.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 12, 2006
    Inventors: Motohiro Yamazaki, Kazumichi Imai
  • Publication number: 20040163962
    Abstract: A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are introduced by applying a high voltage from a high voltage power supply between the sample tray and a coupler in a state in which one-ends of the capillaries are inserted in the samples contained in the sample tray. The apparatus eliminates the necessity of individually inserting electrodes in a plurality of samples contained in the sample tray, thereby making easy works for analysis.
    Type: Application
    Filed: February 26, 2004
    Publication date: August 26, 2004
    Applicants: Hitachi, Ltd., Naka Instruments Co., Ltd.
    Inventors: Kazumichi Imai, Osamu Uchida
  • Publication number: 20040112749
    Abstract: An electrophoresis device capable of supplying a sample accurately without positioning error using a rotary autosampler. A projection (17) is mounted on the lower surface of a detachable carousel (13) on a rotation axis thereof. A projection bearing (18) is mounted on a rotation axis of a turntable (15). The respective central axes are automatically aligned so that no eccentricity is caused by rotation. A pressing means is provided in a heater unit at a position corresponding to the position of the capillary, thereby reducing irregularities in the heating of the capillary. A sample-loaded end of the capillary is passed through a tubular electrode and adapted to operate with the electrode in an integral manner.
    Type: Application
    Filed: February 10, 2004
    Publication date: June 17, 2004
    Inventors: Takehiko Shibasaki, Kazumichi Imai, Satoru Kimura
  • Patent number: 6740219
    Abstract: A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are introduced by applying a high voltage from a high voltage power supply between the sample tray and a coupler in a state in which one-ends of the capillaries are inserted in the samples contained in the sample tray. The apparatus eliminates the necessity of individually inserting electrodes in a plurality of samples contained in the sample tray, thereby making easy works for analysis.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: May 25, 2004
    Assignees: Hitachi, Ltd., Naka Instruments Co., Ltd.
    Inventors: Kazumichi Imai, Osamu Uchida
  • Publication number: 20030178311
    Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries.
    Type: Application
    Filed: April 15, 2003
    Publication date: September 25, 2003
    Applicant: Hitachi, Ltd.
    Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
  • Patent number: 6581225
    Abstract: The present invention provides an air supply mattress control system for the release of air at a controlled pressure and temperature to a user. A mattress or support member is supplied with pressurized air and has a plurality of force activated nozzle valve assemblies positioned across the upper surface of the mattress. When the upper surface of the valves are forced downward, the valves can release air from a manifold within the mattress. The air can be conditioned and pressurized by a pump and an air conditioning unit. Operation controls can be conveniently positioned adjacent a bed frame for setting the operation conditions of the air mattress.
    Type: Grant
    Filed: June 27, 2000
    Date of Patent: June 24, 2003
    Inventor: Kazumichi Imai
  • Patent number: 6572752
    Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary disposed at the pitch of wells on the side of sample plate (within the area of the wells) into electrical contact with a common electrode, the capillaries and electrodes are made integral in construction. When a voltage is applied to the electrophoretic instrument via a common electrode portion, the voltage is applied to the electrodes for each capillary. This enables an inexpensive microtiter plate, etc. to be used and a multiple of capillaries to be simultaneously inserted, attached and detached.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: June 3, 2003
    Assignee: Hitachi, Ltd.
    Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
  • Patent number: 6325908
    Abstract: A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are introduced by applying a high voltage from a high voltage power supply between the sample tray and a coupler in a state in which one-ends of the capillaries are inserted in the samples contained in the sample tray. The apparatus eliminates the necessity of individually inserting electrodes in a plurality of samples contained in the sample tray, thereby making easy works for analysis.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: December 4, 2001
    Assignees: Hitachi, Ltd., NAKA Instruments Co., Ltd.
    Inventors: Kazumichi Imai, Osamu Uchida
  • Patent number: 6191425
    Abstract: A plurality of samples are separated into sample components by means of electrophoresis in a plurality of capillaries. Light is radiated onto the separated sample components. Fluorescence emitted from the sample components is measured by a detector unit. In the detector unit, the fluorescence from the sample components is collected by a lens, filtered by a filter set to select light of predetermined wavelengths, split into four bundle of rays by right-angle prisms, and focussed on four linear array sensors so as to be detected.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: February 20, 2001
    Assignee: Hatachi, Ltd.
    Inventor: Kazumichi Imai
  • Patent number: 5938908
    Abstract: A capillary electrophoresis system comprising a plurality of capillaries filled with a migration medium in which samples to which fluorephore labels are added migrate, a light source providing an excitation light exciting the fluorephore labels, a photo detector detecting a fluorescence radiated from the fluorephore labels, and light focusing means placed between the plurality of capillaries to which the excitation light is irradiated. The parts of the plurality of capillaries to which the excitation light is irradiated and the light focusing means are arranged in a plane shape. The excitation light is irradiated through the plurality of capillaries and the light focusing means, the capillaries and light focusing means alternatively placed in the parts where an excitation light is irradiated. The light focusing means consisting of cylindrical rod lenses.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: August 17, 1999
    Assignees: Hitachi, Ltd., Hitachi Software Engineering Co., Ltd.
    Inventors: Takashi Anazawa, Hideki Kambara, Satoshi Takahashi, Kazumichi Imai, Hisanori Nasu
  • Patent number: 5746977
    Abstract: An automatic analyzer in which a suitable transmission destination remote from a body of the automatic analyzer is selected in accordance with the contents of to be transmitted and the contents are transmitted to the transmission destination; a suitable operation control instruction is received from a suitable person on duty; and a suitable process is carried out to make it possible to improve analysis efficiency.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: May 5, 1998
    Assignee: Hitachi, Ltd.
    Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
  • Patent number: 5695718
    Abstract: An automatic analyzer in which a suitable transmission destination remote from a body of the automatic analyzer is selected in accordance with the contents of to be transmitted and the contents are transmitted to the transmission destination; a suitable operation control instruction is received from a suitable person on duty; and a suitable process is carried out to make it possible to improve analysis efficiency.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: December 9, 1997
    Assignee: Hitachi, Ltd.
    Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
  • Patent number: 5543292
    Abstract: A process for detecting the existence of at least one sequence of oligonucleotide in a nucleic acid sample includes at least one performance of a step of mixing the sample witha labeled common polynucleotide, anda polynucleotide probe comprising a sequence complementary to at least a part of the sequence of oligonucleotide and a sequence complementary to at least a part of the labeled common polynucleotide. The existence of a sequence of oligonucleotide which is an analyte existing in a nucleic acid sample can be detected by the use of a common reagent and an unattached polynucleotide having a base sequence specific for the analyte to be measured.
    Type: Grant
    Filed: June 14, 1993
    Date of Patent: August 6, 1996
    Assignee: Hitachi, Ltd.
    Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
  • Patent number: 5519635
    Abstract: In order to provide an apparatus for chemical analysis capable of eliminating time consuming changing connections of flow paths and analytical elements, and of operating for analysis without any special knowledge, the apparatus for chemical analysis comprises a main body of analytical apparatus provided with sampling device for sucking sample, liquid controller for transferring the sucked sample and reagents, and detector for measuring the sample, and analytical unit provided with a liquid connector and a signal connector for connecting to the main body of analytical apparatus, and memory storing at least analytical method, and analysis of the sample is performed by attaching and fixing the analytical unit to said main body of analytical apparatus, transferring at least analytical method stored in the memory to the main body of analytical apparatus, and analyzing the sample in accordance the said analytical method.
    Type: Grant
    Filed: September 6, 1994
    Date of Patent: May 21, 1996
    Assignee: Hitachi Ltd.
    Inventors: Ryo Miyake, Masaharu Ishii, Hideo Enoki, Isao Yamazaki, Kazumichi Imai, Tadafumi Kuroishi, Yu-ming Hsueh
  • Patent number: 5470534
    Abstract: In a first measurement stage, reaction solutions of samples are optically measured by a biochemical analyzer, and the measurement result of the analysis item which is an index of the disease status regarding the samples is compared with the check index. This check index is stored in memory beforehand. When the measurement result corresponds to the check index, the sample processing goes to a second measurement stage for measuring a specific item. In the second measurement stage, the sample is measured by an immuno-assay apparatus or a nucleic acid analyzer, and the measurement result is outputted.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: November 28, 1995
    Assignee: Hitachi, Ltd.
    Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
  • Patent number: 5365559
    Abstract: A particle counting apparatus for counting a total particle counting value contained in a liquid sample comprising, a flow cell in which the liquid sample flows, a light source for irradiating a light beam to the sample liquid in the flow cell, a detector for detecting pulse-wise signal scattered from the particles by the irradiating of the light beam, and a computer for obtaining the total particle counting value contained in the liquid sample as a counting value measured when the top end of the liquid sample is irradiated with the light beam and the plural particles in the top end does not overlapped in the light beam, multiplied by a coefficient.
    Type: Grant
    Filed: January 26, 1993
    Date of Patent: November 15, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Yu-Ming Hsueh, Kazumichi Imai, Masataka Koga
  • Patent number: 5211829
    Abstract: The present invention is applied to an analyzer according to which a sample to be analyzed is moved through a capillary tube in liquid chromatography or capillary-zone electrophoretic method. The capillary tube has a separation zone and a detection zone. The capillary tube in the detection zone has a section in which it can vibrate and both ends of this section are fixed.Analytes of the sample introduced into the analyzer are separated from each other in the separation zone. When each of the separated analytes is led to the area irradiated with beam in the detection zone, the capillary tube in the detection zone vibrates. This vibration phenomenon is brought about by tension fluctuation of the capillary tube caused by intermittent irradiation of the detection zone with an excitation beam and absorption of the excitation beam by the analyte. Concentration of analytes in the sample can be measured by detecting amplitude of the vibration.
    Type: Grant
    Filed: March 4, 1991
    Date of Patent: May 18, 1993
    Assignee: Hitachi, Ltd.
    Inventors: Kazumichi Imai, Masataka Koga, Takehiko Kitamori, Tsuguo Sawada, Jiaqi Wu
  • Patent number: D430304
    Type: Grant
    Filed: February 3, 1999
    Date of Patent: August 29, 2000
    Assignee: Hitachi, Ltd.
    Inventors: Mitsuru Oonuma, Seiji Kamimura, Atsushi Ninomiya, Isamu Takekoshi, Kazumichi Imai