Patents by Inventor Kazumichi Imai
Kazumichi Imai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060086612Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary disposed at the pitch of wells on the side of sample plate (within the area of the wells) into electrical contact with a common electrode, the capillaries and electrodes are made integral in construction. When a voltage is applied to the electrophoretic instrument via a common electrode portion, the voltage is applied to the electrodes for each capillary. This enables an inexpensive microtiter plate, etc. to be used and a multiple of capillaries to be simultaneously inserted, attached and detached.Type: ApplicationFiled: December 8, 2005Publication date: April 27, 2006Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
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Patent number: 7014746Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary disposed at the pitch of wells on the side of sample plate (within the area of the wells) into electrical contact with a common electrode, the capillaries and electrodes are made integral in construction. When a voltage is applied to the electrophoretic instrument via a common electrode portion, the voltage is applied to the electrodes for each capillary. This enables an inexpensive microtiter plate, etc. to be used and a multiple of capillaries to be simultaneously inserted, attached and detached.Type: GrantFiled: April 15, 2003Date of Patent: March 21, 2006Assignee: Hitachi, Ltd.Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
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Publication number: 20060006066Abstract: Analysis is performed efficiently in an electrophoresis apparatus while avoiding deterioration of samples. A plurality of sample plates are stored in frozen storage. When a particular sample plate is being analyzed, other sample plates are stored in a standby unit. In this way, a plurality of sample plates can be stored under cool conditions and analysis can be performed efficiently.Type: ApplicationFiled: July 7, 2005Publication date: January 12, 2006Inventors: Motohiro Yamazaki, Kazumichi Imai
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Publication number: 20040163962Abstract: A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are introduced by applying a high voltage from a high voltage power supply between the sample tray and a coupler in a state in which one-ends of the capillaries are inserted in the samples contained in the sample tray. The apparatus eliminates the necessity of individually inserting electrodes in a plurality of samples contained in the sample tray, thereby making easy works for analysis.Type: ApplicationFiled: February 26, 2004Publication date: August 26, 2004Applicants: Hitachi, Ltd., Naka Instruments Co., Ltd.Inventors: Kazumichi Imai, Osamu Uchida
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Publication number: 20040112749Abstract: An electrophoresis device capable of supplying a sample accurately without positioning error using a rotary autosampler. A projection (17) is mounted on the lower surface of a detachable carousel (13) on a rotation axis thereof. A projection bearing (18) is mounted on a rotation axis of a turntable (15). The respective central axes are automatically aligned so that no eccentricity is caused by rotation. A pressing means is provided in a heater unit at a position corresponding to the position of the capillary, thereby reducing irregularities in the heating of the capillary. A sample-loaded end of the capillary is passed through a tubular electrode and adapted to operate with the electrode in an integral manner.Type: ApplicationFiled: February 10, 2004Publication date: June 17, 2004Inventors: Takehiko Shibasaki, Kazumichi Imai, Satoru Kimura
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Patent number: 6740219Abstract: A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are introduced by applying a high voltage from a high voltage power supply between the sample tray and a coupler in a state in which one-ends of the capillaries are inserted in the samples contained in the sample tray. The apparatus eliminates the necessity of individually inserting electrodes in a plurality of samples contained in the sample tray, thereby making easy works for analysis.Type: GrantFiled: May 10, 2001Date of Patent: May 25, 2004Assignees: Hitachi, Ltd., Naka Instruments Co., Ltd.Inventors: Kazumichi Imai, Osamu Uchida
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Publication number: 20030178311Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries.Type: ApplicationFiled: April 15, 2003Publication date: September 25, 2003Applicant: Hitachi, Ltd.Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
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Patent number: 6581225Abstract: The present invention provides an air supply mattress control system for the release of air at a controlled pressure and temperature to a user. A mattress or support member is supplied with pressurized air and has a plurality of force activated nozzle valve assemblies positioned across the upper surface of the mattress. When the upper surface of the valves are forced downward, the valves can release air from a manifold within the mattress. The air can be conditioned and pressurized by a pump and an air conditioning unit. Operation controls can be conveniently positioned adjacent a bed frame for setting the operation conditions of the air mattress.Type: GrantFiled: June 27, 2000Date of Patent: June 24, 2003Inventor: Kazumichi Imai
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Patent number: 6572752Abstract: The troublesomeness during the setting of a plurality of capillaries is eliminated by composing pairs of electrodes, which are electrically connected to the common electrode, and capillaries. By bringing electrodes installed in the vicinity of each capillary disposed at the pitch of wells on the side of sample plate (within the area of the wells) into electrical contact with a common electrode, the capillaries and electrodes are made integral in construction. When a voltage is applied to the electrophoretic instrument via a common electrode portion, the voltage is applied to the electrodes for each capillary. This enables an inexpensive microtiter plate, etc. to be used and a multiple of capillaries to be simultaneously inserted, attached and detached.Type: GrantFiled: September 27, 2000Date of Patent: June 3, 2003Assignee: Hitachi, Ltd.Inventors: Muneo Maeshima, Kazumichi Imai, Masaya Kojima, Satoshi Takahashi, Hiromi Yamashita
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Patent number: 6325908Abstract: A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are introduced by applying a high voltage from a high voltage power supply between the sample tray and a coupler in a state in which one-ends of the capillaries are inserted in the samples contained in the sample tray. The apparatus eliminates the necessity of individually inserting electrodes in a plurality of samples contained in the sample tray, thereby making easy works for analysis.Type: GrantFiled: August 11, 1998Date of Patent: December 4, 2001Assignees: Hitachi, Ltd., NAKA Instruments Co., Ltd.Inventors: Kazumichi Imai, Osamu Uchida
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Patent number: 6191425Abstract: A plurality of samples are separated into sample components by means of electrophoresis in a plurality of capillaries. Light is radiated onto the separated sample components. Fluorescence emitted from the sample components is measured by a detector unit. In the detector unit, the fluorescence from the sample components is collected by a lens, filtered by a filter set to select light of predetermined wavelengths, split into four bundle of rays by right-angle prisms, and focussed on four linear array sensors so as to be detected.Type: GrantFiled: February 13, 1998Date of Patent: February 20, 2001Assignee: Hatachi, Ltd.Inventor: Kazumichi Imai
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Patent number: 5938908Abstract: A capillary electrophoresis system comprising a plurality of capillaries filled with a migration medium in which samples to which fluorephore labels are added migrate, a light source providing an excitation light exciting the fluorephore labels, a photo detector detecting a fluorescence radiated from the fluorephore labels, and light focusing means placed between the plurality of capillaries to which the excitation light is irradiated. The parts of the plurality of capillaries to which the excitation light is irradiated and the light focusing means are arranged in a plane shape. The excitation light is irradiated through the plurality of capillaries and the light focusing means, the capillaries and light focusing means alternatively placed in the parts where an excitation light is irradiated. The light focusing means consisting of cylindrical rod lenses.Type: GrantFiled: April 22, 1997Date of Patent: August 17, 1999Assignees: Hitachi, Ltd., Hitachi Software Engineering Co., Ltd.Inventors: Takashi Anazawa, Hideki Kambara, Satoshi Takahashi, Kazumichi Imai, Hisanori Nasu
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Patent number: 5746977Abstract: An automatic analyzer in which a suitable transmission destination remote from a body of the automatic analyzer is selected in accordance with the contents of to be transmitted and the contents are transmitted to the transmission destination; a suitable operation control instruction is received from a suitable person on duty; and a suitable process is carried out to make it possible to improve analysis efficiency.Type: GrantFiled: September 13, 1996Date of Patent: May 5, 1998Assignee: Hitachi, Ltd.Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
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Patent number: 5695718Abstract: An automatic analyzer in which a suitable transmission destination remote from a body of the automatic analyzer is selected in accordance with the contents of to be transmitted and the contents are transmitted to the transmission destination; a suitable operation control instruction is received from a suitable person on duty; and a suitable process is carried out to make it possible to improve analysis efficiency.Type: GrantFiled: March 16, 1995Date of Patent: December 9, 1997Assignee: Hitachi, Ltd.Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
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Patent number: 5543292Abstract: A process for detecting the existence of at least one sequence of oligonucleotide in a nucleic acid sample includes at least one performance of a step of mixing the sample witha labeled common polynucleotide, anda polynucleotide probe comprising a sequence complementary to at least a part of the sequence of oligonucleotide and a sequence complementary to at least a part of the labeled common polynucleotide. The existence of a sequence of oligonucleotide which is an analyte existing in a nucleic acid sample can be detected by the use of a common reagent and an unattached polynucleotide having a base sequence specific for the analyte to be measured.Type: GrantFiled: June 14, 1993Date of Patent: August 6, 1996Assignee: Hitachi, Ltd.Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
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Patent number: 5519635Abstract: In order to provide an apparatus for chemical analysis capable of eliminating time consuming changing connections of flow paths and analytical elements, and of operating for analysis without any special knowledge, the apparatus for chemical analysis comprises a main body of analytical apparatus provided with sampling device for sucking sample, liquid controller for transferring the sucked sample and reagents, and detector for measuring the sample, and analytical unit provided with a liquid connector and a signal connector for connecting to the main body of analytical apparatus, and memory storing at least analytical method, and analysis of the sample is performed by attaching and fixing the analytical unit to said main body of analytical apparatus, transferring at least analytical method stored in the memory to the main body of analytical apparatus, and analyzing the sample in accordance the said analytical method.Type: GrantFiled: September 6, 1994Date of Patent: May 21, 1996Assignee: Hitachi Ltd.Inventors: Ryo Miyake, Masaharu Ishii, Hideo Enoki, Isao Yamazaki, Kazumichi Imai, Tadafumi Kuroishi, Yu-ming Hsueh
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Patent number: 5470534Abstract: In a first measurement stage, reaction solutions of samples are optically measured by a biochemical analyzer, and the measurement result of the analysis item which is an index of the disease status regarding the samples is compared with the check index. This check index is stored in memory beforehand. When the measurement result corresponds to the check index, the sample processing goes to a second measurement stage for measuring a specific item. In the second measurement stage, the sample is measured by an immuno-assay apparatus or a nucleic acid analyzer, and the measurement result is outputted.Type: GrantFiled: May 2, 1994Date of Patent: November 28, 1995Assignee: Hitachi, Ltd.Inventors: Kyoko Imai, Kazumichi Imai, Yasushi Nomura
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Patent number: 5365559Abstract: A particle counting apparatus for counting a total particle counting value contained in a liquid sample comprising, a flow cell in which the liquid sample flows, a light source for irradiating a light beam to the sample liquid in the flow cell, a detector for detecting pulse-wise signal scattered from the particles by the irradiating of the light beam, and a computer for obtaining the total particle counting value contained in the liquid sample as a counting value measured when the top end of the liquid sample is irradiated with the light beam and the plural particles in the top end does not overlapped in the light beam, multiplied by a coefficient.Type: GrantFiled: January 26, 1993Date of Patent: November 15, 1994Assignee: Hitachi, Ltd.Inventors: Yu-Ming Hsueh, Kazumichi Imai, Masataka Koga
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Patent number: 5211829Abstract: The present invention is applied to an analyzer according to which a sample to be analyzed is moved through a capillary tube in liquid chromatography or capillary-zone electrophoretic method. The capillary tube has a separation zone and a detection zone. The capillary tube in the detection zone has a section in which it can vibrate and both ends of this section are fixed.Analytes of the sample introduced into the analyzer are separated from each other in the separation zone. When each of the separated analytes is led to the area irradiated with beam in the detection zone, the capillary tube in the detection zone vibrates. This vibration phenomenon is brought about by tension fluctuation of the capillary tube caused by intermittent irradiation of the detection zone with an excitation beam and absorption of the excitation beam by the analyte. Concentration of analytes in the sample can be measured by detecting amplitude of the vibration.Type: GrantFiled: March 4, 1991Date of Patent: May 18, 1993Assignee: Hitachi, Ltd.Inventors: Kazumichi Imai, Masataka Koga, Takehiko Kitamori, Tsuguo Sawada, Jiaqi Wu
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Patent number: D430304Type: GrantFiled: February 3, 1999Date of Patent: August 29, 2000Assignee: Hitachi, Ltd.Inventors: Mitsuru Oonuma, Seiji Kamimura, Atsushi Ninomiya, Isamu Takekoshi, Kazumichi Imai