Patents by Inventor Kazuya Yamano

Kazuya Yamano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110027271
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: June 16, 2010
    Publication date: February 3, 2011
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yutaka KANDA, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7858091
    Abstract: Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: December 28, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Kazuya Yamano, Susumu Sekine, Mitsuo Satoh, Toshio Ota, Akiko Furuya, Kenji Shibata, Yuki Kobayashi, Miho Takebayashi, Yusuke Nakamura, Sumio Sugano
  • Patent number: 7846725
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, wherein the expression of GDP-mannose 4,6-dehydrogenase is inhibited by RNA interference.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: December 7, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7741442
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: June 22, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7737325
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-modulated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: June 15, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20100143388
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: November 30, 2009
    Publication date: June 10, 2010
    Applicant: KYOWA HAKKO KIRIN CO., LTD
    Inventors: YUTAKA KANDA, MITSUO SATOH, KAZUYASU NAKAMURA, KAZUHISA UCHIDA, TOYOHIDE SHINKAWA, NAOKO YAMANE, EMI HOSAKA, KAZUYA YAMANO, MOTOO YAMASAKI, NOBUO HANAI
  • Patent number: 7691810
    Abstract: The present invention provides a process for producing an antithrombin III composition comprising an antithrombin III molecule having complex type N-glycoside-linked sugar chains, wherein the complex type N-glycoside-linked sugar chains have a structure in which fucose is not bound to N-acetylglucosamine in the reducing end in the sugar chains.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: April 6, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Tsuyoshi Yamada, Mitsuo Satoh, Yutaka Kanda, Kazuya Yamano
  • Publication number: 20090261649
    Abstract: The present invention provides a brake booster in which an excellent pedal feeling can be provided even though a brake fluid pressure control unit is disposed between the brake booster and a wheel cylinder. The brake booster according to the present invention performs different methods for controlling a booster based on whether the fluid pressure control unit is in operation, and controls a displacement amount of an assist member so that a change in a master cylinder pressure is within a predetermined range even when the fluid pressure control unit is in operation.
    Type: Application
    Filed: March 23, 2009
    Publication date: October 22, 2009
    Inventors: Motohiro Higuma, Kazuya Yamano, Takanobu Saito, Satoru Kuragaki
  • Publication number: 20090228994
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: March 24, 2009
    Publication date: September 10, 2009
    Applicant: KYOWA HAKKO KOGYO., LTD.
    Inventors: Yutaka KANDA, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20090191199
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: January 9, 2009
    Publication date: July 30, 2009
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yutaka KANDA, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20090191592
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: January 9, 2009
    Publication date: July 30, 2009
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yutaka KANDA, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7558662
    Abstract: In vehicular driving control apparatus and method, a steering assistance force provided for steerable road wheels of the vehicle in a direction at which a sideslip angle is decreased when a vehicular sideslip angle which is a difference between a forwarding direction of the vehicle and a steering direction of a steering wheel of the vehicle is detected and a vehicular oversteer state is detected, and thereafter, each of road wheels of the vehicle is controlled to decrease the sideslip angle when the steering assistance force is provided in a direction at which the vehicular sideslip angle is decreased and when the sideslip angle is equal to or larger than a predetermined value.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: July 7, 2009
    Assignee: Hitachi, Ltd.
    Inventors: Naoshi Yamaguchi, Mitsuo Sasaki, Kazuya Yamano, Toru Takahashi, Motohiro Higuma
  • Publication number: 20080261301
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: April 1, 2008
    Publication date: October 23, 2008
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Publication number: 20080241960
    Abstract: Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.
    Type: Application
    Filed: January 11, 2008
    Publication date: October 2, 2008
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Kazuya Yamano, Susumu Sekine, Mitsuo Satoh, Toshio Ota, Akiko Furuya, Kenji Shibata, Yuki Kobayashi, Miho Takebayashi, Yusuke Nakamura, Sumio Sugano
  • Publication number: 20080227196
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Application
    Filed: March 14, 2008
    Publication date: September 18, 2008
    Inventors: Yutaka Kanda, Mitsuo Satch, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7425446
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: September 16, 2008
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7393683
    Abstract: The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: July 1, 2008
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Yutaka Kanda, Mitsuo Satoh, Kazuyasu Nakamura, Kazuhisa Uchida, Toyohide Shinkawa, Naoko Yamane, Emi Hosaka, Kazuya Yamano, Motoo Yamasaki, Nobuo Hanai
  • Patent number: 7332301
    Abstract: Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: February 19, 2008
    Assignee: Kyowa Haakko Kogyo Co. Ltd.
    Inventors: Kazuya Yamano, Susumu Sekine, Mitsuo Satoh, Toshio Ota, Akiko Furuya, Kenji Shibata, Yuki Kobayashi, Miho Takebayashi, Yusuke Nakamura, Sumio Sugano
  • Publication number: 20070074926
    Abstract: A power assist mechanism is provided that assists operation of a steering mechanism when receiving a pressurized hydraulic fluid. A hydraulic pump feeds the power assist mechanism with the pressurized hydraulic fluid when driven. An electric motor drives the hydraulic pump. A battery unit is provided for energizing the electric motor. A control unit is provided for controlling the electric power from the battery unit to the electric motor. The battery unit comprises a plurality of lead-acid batteries that are connected in series. Each lead-acid battery comprises a spirally wound positive plate, a spirally wound negative plate, a spirally wound insulating plate that is spirally wound and sandwiched between the positive and negative plates, a battery case that puts therein the spirally wound positive, negative and insulating plates and an electrolyte that is provided in the battery case.
    Type: Application
    Filed: July 17, 2006
    Publication date: April 5, 2007
    Inventors: Toru Takahashi, Toshimitsu Sakaki, Tadaharu Yokota, Kazuya Yamano, Kyoko Honbo, Masanori Sakai
  • Publication number: 20070032937
    Abstract: In vehicular driving control apparatus and method, a steering assistance force provided for steerable road wheels of the vehicle in a direction at which a sideslip angle is decreased when a vehicular sideslip angle which is a difference between a forwarding direction of the vehicle and a steering direction of a steering wheel of the vehicle is detected and a vehicular oversteer state is detected, and thereafter, each of road wheels of the vehicle is controlled to decrease the sideslip angle when the steering assistance force is provided in a direction at which the vehicular sideslip angle is decreased and when the sideslip angle is equal to or larger than a predetermined value.
    Type: Application
    Filed: July 19, 2006
    Publication date: February 8, 2007
    Inventors: Naoshi Yamaguchi, Mitsuo Sasaki, Kazuya Yamano, Toru Takahashi, Motohiro Higuma